21 CFR § 522.2474Chapter I

§ 522.2474 Tolazoline.

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Verbatim text below is from the Electronic Code of Federal Regulations (eCFR), a public-domain U.S. government work. Always verify the current version with the eCFR before relying on it for any legal matter.

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Specifications.(a) Each milliliter of solution contains tolazoline hydrochloride equivalent to 100 milligrams (mg) of base activity.

Sponsor.(b) See No. 059399 in § 510.600(c) of this chapter.

Conditions of use in horsesAmount.(c) —(1) Administer slowly by intravenous injection 4 mg per kilogram of body weight or 1.8 mg per pound (4 milliliters (mL) per 100 kilograms or 4 mL per 220 pounds).

Indications for use.(2) For use in horses when it is desirable to reverse the effects of sedation and analgesia caused by xylazine.

Limitations.(3) Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[79 FR 16197, Mar. 25, 2014, as amended at 79 FR 74020, Dec. 15, 2014; 80 FR 13230, Mar. 13, 2015]

eCFR data current as of: June 10, 2026

This is legal information, not legal advice. Laws vary by jurisdiction and change frequently. Always verify current law with official sources and consult a licensed attorney in your jurisdiction for advice on your specific situation.