21 CFR § 522.1222Chapter I

§ 522.1222 Ketamine.

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Verbatim text below is from the Electronic Code of Federal Regulations (eCFR), a public-domain U.S. government work. Always verify the current version with the eCFR before relying on it for any legal matter.

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Specifications.(a) Each milliliter contains ketamine hydrochloride equivalent to 100 milligrams (mg) ketamine base activity.

Sponsors.(b) See Nos. 00010, 017033, 054771, 058198, 059399, and 069043 in § 510.600(c) of this chapter.

Special considerations.(c) Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Conditions of useCatsAmount.(d) —(1) —(i) 5 to 15 mg/pound body weight intramuscularly, depending on the effect desired.

Indications for use.(ii) For restraint or as the sole anesthetic agent in diagnostic or minor, brief surgical procedures that do not require skeletal muscle relaxation.

Subhuman primatesAmount.(2) —(i) 3 to 15 mg/kilogram body weight intramuscularly, depending upon the species, general condition, and age of the subject.

Indications for use.(ii) For restraint.

[67 FR 17283, Apr. 10, 2002, as amended at 73 FR 8192, Feb. 13, 2008. Redesignated at 79 FR 16191, Mar. 25, 2014, as amended at 80 FR 13229, Mar. 13, 2015; 83 FR 48946, Sept. 28, 2018; 86 FR 14820, Mar. 19, 2021; 88 FR 27699, May 3, 2023; 88 FR 55564, Aug. 16, 2023]

eCFR data current as of: June 10, 2026

This is legal information, not legal advice. Laws vary by jurisdiction and change frequently. Always verify current law with official sources and consult a licensed attorney in your jurisdiction for advice on your specific situation.