§ 520.1195 Ivermectin liquid.

Specifications.(a) (1) Each milliliter (mL) contains 10 milligrams (mg) ivermectin.

(2) Each mL of micellar solution contains 0.8 mg ivermectin.

Sponsors.(b) See sponsor numbers in § 510.600(c) of this chapter.

(1) Nos. 058005 and 058198 for use of product described in paragraph (a)(1) of this section as in paragraphs (e)(1)(i), (e)(1)(ii)(A), and (e)(1)(iii) of this section.

(2) No. 058829 for use of product described in paragraph (a)(1) of this section as in paragraphs (e)(1)(i), (e)(1)(ii)(B), and (e)(1)(iii) of this section.

(3) Nos. 000010 and 058829 for use of product described in paragraph (a)(2) of this section as in paragraph (e)(2) of this section.

Related tolerances.(c) See § 556.344 of this chapter.

Special considerations.(d) See § 500.25 of this chapter.

Conditions of useHorsesAmount.(e) —(1) —(i) 200 micrograms (mcg) per kilogram (/kg) of body weight as a single dose by stomach tube or as an oral drench.

Indications for use.(ii) For treatment and control of:

Strongylus vulgarisS. edentatusS. equinusTriodontophorusT. brevicaudaT. serratusCraterostomum acuticaudatumCoronocyclusC. coronatusC. labiatusC. labratusCyathostomumC. catinatumC. pateratumCylicocyclusC. insigneC. leptostomumC. nassatusC. brevicapsulatusCylicodontophorusCylicostephanusC. calicatusC. goldiC. longibursatusC. minutusPetrovinema poculatumOxyuris equiParascaris equorumTrichostrongylus axeiHabronema muscaeGasterophilusG. intestinalisG. nasalisDictyocaulus arnfieldiStrongyloides westeriHabronemaDraschiaOnchocerca(A) Large Strongyles (adults): (also early forms in blood vessels), (also tissue stages), , spp. Including and , and ; Small Strongyles (adults, including those resistant to some benzimidazole class compounds): spp. Including , , and , spp. Including and , spp. Including , , , and , spp., spp. Including , , , and , and ; Small Strongyles (fourth-stage larvae); Pinworms (adults and fourth stage larvae): ; Ascarids (adults and third- and fourth-stage larvae): ; Hairworms (adults): ; Large mouth Stomach Worms (adults): ; Bots (oral and gastric stages): spp. Including and ; Lungworms (adults and fourth-stage larvae): ; Intestinal Threadworms (adults), ; Summer Sores caused by and spp. Cutaneous third-stage larvae; Dermatitis caused by neck threadworm microfilariae, sp.

Strongylus equinusS. vulgarisS. endentatusTriodontophorusCyathostomumCylicocyclusCylicodontophorusCylicostephanusOxyuris equiParascaris equorumTrichostongylus axeiHabronema muscaeGastrophilusDictyocaulus arnfieldiStrongyloides westeriHabronemaDraschiaOnchocerca(B) Large Strongyles ( (adult), (adult and arterial larval stages), (adult and migrating tissue stages), spp. (adult)); Small Strongyles including those resistant to some benzimidazole class compounds ( spp. (adult and fourth-stage larvae), spp., spp., spp.); Pinworms ( (adult and fourth-stage larvae)); Ascarids ( (adult and third- and fourth-stage larvae)); Hairworms ( ( adult)); Large mouth Stomach Worms ( (adult)); Stomach Bots ( spp. (oral and gastric stages)); Lungworms ( (adult and fourth-stage larvae)); intestinal threadworms ( (adult)); Summer Sores caused by and spp. Cutaneous third-stage larvae; and Dermatitis caused by neck threadworm microfilariae ( spp.).

Limitations.(iii) Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

SheepAmount.(2) —(i) 200 mcg/kg (3 mL/26 pounds) of body weight as a single dose oral drench.

Indications for use.Haemonchus contortus, H. placeiOstertagia circumcincta, Trichostrongylus axei, T. colubriformis, Cooperia oncophoraC. curticei, Oesophagostomum columbianum, O. venulosumNematodirus battus, N. spathiger, S. papillosusChabertia ovinaTrichuris ovisD. filariaOestrus ovis.(ii) For treatment and control of the adult and fourth-stage larvae of gastrointestinal roundworms ( (adults only), (adults only), (adults only), (adults only), (adult only), (adults only)); lungworms (); and all larval stages of the nasal bot

Limitations.(iii) For use in sheep only. Do not use in other animal species as severe adverse reactions, including fatalities in dogs, may result. Do not treat sheep within 11 days of slaughter.

[67 FR 50597, Aug. 5, 2002, as amended at 69 FR 57173, Sept. 24, 2004; 71 FR 13542, Mar. 16, 2006; 71 FR 38072, July 5, 2006; 72 FR 9456, Feb. 21, 2008; 78 FR 17596, Mar. 22, 2013; 79 FR 10964, Feb. 27, 2014; 84 FR 39183, Aug. 9, 2019; 86 FR 14818, Mar. 19, 2021; 88 FR 27698, May 3, 2023; 88 FR 84700, Dec. 6, 2023]