Significant New Use Rules on Certain Chemical Substances (25-3.5e)

Issuing agencies

Abstract

EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.

Full Text

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<title>Federal Register, Volume 91 Issue 213 (Thursday, November 5, 2026)</title>
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[Federal Register Volume 91, Number 213 (Thursday, November 5, 2026)]
[Rules and Regulations]
[Pages 69704-69720]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2026-22576]


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ENVIRONMENTAL PROTECTION AGENCY

40 CFR Part 721

[EPA-HQ-OPPT-2025-2169; FRL-13126-03-OCSPP]
RIN 2070-AB27


Significant New Use Rules on Certain Chemical Substances (25-
3.5e)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Final rule.

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SUMMARY: EPA is issuing significant new use rules (SNURs) under the 
Toxic Substances Control Act (TSCA) for certain chemical substances 
that were the subject of premanufacture notices (PMNs) and are also 
subject to an Order issued by EPA pursuant to TSCA. The SNURs require 
persons to notify EPA at least 90 days before commencing the 
manufacture (defined by statute to include import) or processing of any 
of these chemical substances for an activity that is designated as a 
significant new use in the SNUR. The required notification initiates 
EPA's evaluation of the conditions of that use for that chemical 
substance. In addition, the manufacture or processing for the 
significant new use may not commence until EPA has conducted a review 
of the required notification; made an appropriate determination 
regarding that notification; and taken such actions as required by that 
determination.

DATES: This rule is effective on January 4, 2027. For purposes of 
judicial review, this rule shall be promulgated at 1 p.m. (EST) on 
November 19, 2026.

ADDRESSES: The docket for this action, identified under docket 
identification (ID) number EPA-HQ-OPPT-2025-2169, is available online 
at <a href="https://www.regulations.gov">https://www.regulations.gov</a> or in person at the Office of Pollution 
Prevention and Toxics Docket (OPPT Docket) in the Environmental 
Protection Agency Docket Center (EPA/DC). Please review the visitor 
instructions and additional information about the docket available at 
<a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>.

FOR FURTHER INFORMATION CONTACT: 
    For technical information: Joseph Said, New Chemicals Division 
(7405M), Office of Pollution Prevention and Toxics, Environmental 
Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-
0001; telephone number: (202) 566-0848; email address: 
<a href="/cdn-cgi/l/email-protection#9ae9fbf3feb4f0f5e9ffeaf2daffeafbb4fdf5ec"><span class="__cf_email__" data-cfemail="01726068652f6b6e72647169416471602f666e77">[email&#160;protected]</span></a>.
    For general information on SNURs: Iliriana Mushkolaj, New Chemicals 
Division (7405M), Office of Pollution Prevention and Toxics, 
Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, 
DC 20460-0001; telephone number: (202) 564-6877; email address: 
<a href="/cdn-cgi/l/email-protection#503d2523383b3f3c313a7e393c392239313e31103520317e373f26"><span class="__cf_email__" data-cfemail="85e8f0f6edeeeae9e4efabece9ecf7ece4ebe4c5e0f5e4abe2eaf3">[email&#160;protected]</span></a>.
    For general information on TSCA: The TSCA Assistance Information 
Service Hotline, Goodwill of the Finger Lakes, 422 South Clinton Ave., 
Rochester, NY 14620; telephone number: (202) 554-1404; email address: 
<a href="/cdn-cgi/l/email-protection#26727565670b6e49524a4f48436643564708414950"><span class="__cf_email__" data-cfemail="92c6c1d1d3bfdafde6fefbfcf7d2f7e2f3bcf5fde4">[email&#160;protected]</span></a>.

SUPPLEMENTARY INFORMATION:

I. Executive Summary

A. What is the Agency's authority for taking this action?

    TSCA section 5(a)(2) (15 U.S.C. 2604(a)(2)) authorizes EPA to 
determine that a use of a chemical substance is a ``significant new 
use.'' EPA must make this determination by rule after considering all 
relevant factors, including the factors in TSCA section 5(a)(2).

B. What action is the Agency taking?

    EPA is finalizing SNURs under TSCA section 5(a)(2) for the chemical 
substances identified in this document. These chemical substances were 
the subject of PMNs and are also subject to an Order issued by EPA 
pursuant to TSCA section 5(e)(1)(A), as required by the determinations 
made under TSCA section 5(a)(3)(B). The SNURs identify as significant 
new uses any manufacturing, processing, use, distribution in commerce, 
or disposal that does not conform to the restrictions imposed by the 
underlying TSCA Orders, consistent with TSCA section 5(f)(4). The SNURs 
require persons who intend to manufacture or process any of these 
chemical substances for an activity that is designated as a significant 
new use in the SNURs to notify EPA at least 90 days before commencing 
that activity.
    Previously, EPA proposed SNURs for these chemical substances in the 
Federal Register of June 5, 2026 (91 FR 34480 (FRL-13126-01-OCSPP)). 
The docket includes information considered by the Agency in developing 
the proposed and final rules, including public comments and EPA's 
responses to the comments received as discussed in Unit II.D.

C. Does this action apply to me?

1. General Applicability
    This action applies to you if you manufacture, process, or use the 
chemical substances identified in this document. The following list of 
North American Industrial Classification System (NAICS) codes is not 
intended to be exhaustive, but rather provides a guide to help readers 
determine whether this document applies to them. Potentially affected 
entities may include:
    <bullet> Manufacturers or processors of one or more subject 
chemical substances (NAICS codes 325 and 324110), e.g., chemical 
manufacturing and petroleum refineries.
2. Applicability to Importers and Exporters
    This action may also apply to certain entities through pre-existing 
import certification and export notification requirements under TSCA 
(<a href="https://www.epa.gov/tsca-import-export-requirements">https://www.epa.gov/tsca-import-export-requirements</a>).
    Chemical importers are subject to TSCA section 13 (15 U.S.C. 2612), 
the requirements in 19 CFR 12.118 through 12.127, 19 CFR 127.28, and 40 
CFR part 707, subpart B. Importers of chemical substances in bulk form, 
as part of a mixture, or as part of an article (if required by rule) 
must certify that the shipment of the chemical substance complies with 
all applicable rules and orders under TSCA, including regulations 
issued under TSCA sections 5, 6, 7 and Title IV.
    Pursuant to 40 CFR 721.20, any persons who export or intend to 
export a chemical substance identified in this document are subject to 
the export notification provisions of TSCA section 12(b) (15 U.S.C. 
2611(b)) and must comply with the export notification requirements in 
40 CFR part 707, subpart D.

D. What are the incremental economic impacts of this action?

    EPA has evaluated the potential costs of establishing SNUN 
reporting requirements for potential manufacturers and processors of 
the chemical substances identified in this

[[Page 69705]]

document. This analysis, which is available in the docket, is briefly 
summarized here.
1. Estimated Costs for SNUN Submissions
    A SNUR requires that any person who intends to engage in such 
activity in the future must first notify EPA by submitting a SNUN. If a 
SNUN is submitted, costs are an estimated $45,000 per SNUN submission 
for large business submitters and $14,500 for small business 
submitters. These estimates include the cost to prepare and submit the 
SNUN (including registration for EPA's Central Data Exchange (CDX)), 
and the payment of a user fee. Businesses that submit a SNUN would be 
subject to either a $37,000 user fee required by 40 CFR 
700.45(c)(2)(ii) and (d), or, if they are a small business as defined 
at 13 CFR 121.201, a reduced user fee of $6,480 (40 CFR 
700.45(c)(1)(ii) and (d)). These estimates reflect the costs and fees 
as they are known at the time of this rulemaking.
2. Estimated Costs for Export Notifications
    EPA has also evaluated the potential costs associated with the pre-
existing export notification requirements under TSCA section 12(b) and 
the implementing regulations at 40 CFR part 707, subpart D. For persons 
exporting a substance that is the subject of a SNUR, a one-time notice 
to EPA must be provided for the first export or intended export to a 
particular country. The total costs of export notification will vary by 
chemical, depending on the number of required notifications (i.e., the 
number of countries to which the chemical is exported). While EPA is 
unable to make any estimate of the likely number of export 
notifications for the chemical substances covered by these SNURs, as 
stated in the accompanying economic analysis, the estimated cost of the 
export notification requirement on a per unit basis is approximately 
$106.

II. Background

A. General Information About SNURs

    Unit II. of the proposed rule provides general information about 
SNURs, and additional information about EPA's new chemical program is 
available at <a href="https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca">https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca</a>.

B. Applicability of the Significant New Use Designation

    To establish a significant new use, EPA must determine that the use 
is not ongoing. As discussed in Unit II.E. of the proposed rule, EPA 
concluded that the proposed significant new uses were not ongoing. If 
EPA subsequently determines that such a use was ongoing as of the date 
of publication of the proposed rule and did not cease prior to issuance 
of the final rule, EPA will not designate that use as a significant new 
use in the final rule. EPA has no information to suggest that any of 
the significant new uses identified in this rule meet this criterion.
    As discussed in the Federal Register of April 24, 1990 (55 FR 17376 
(FRL-3658-5)), EPA believes that the intent of TSCA section 5(a)(1)(B) 
is best served by designating a use as a significant new use as of the 
date of publication of the proposed rule rather than as of the 
effective date of the final rule. The objective of EPA's approach is to 
ensure that a person cannot impede finalization of a SNUR by initiating 
a significant new use after publication of the proposed rule but before 
the effective date of the final rule. Uses arising after the 
publication of the proposed rule are distinguished from uses that are 
identified in the final rule as having been ongoing on the date of 
publication of the proposed rule. The former would be new uses, the 
latter ongoing uses, except that uses that are identified as ongoing as 
of the publication of the proposed rule would not be considered ongoing 
uses if they have ceased by the date of issuance of a final rule.
    In the unlikely event that before a final rule becomes effective a 
person begins commercial manufacturing (including importing) or 
processing of the chemical substances for a use that is designated as a 
significant new use in that final rule, such a person would have to 
cease any such activity upon the effective date of the final rule. To 
resume their activities, these persons would have to first comply with 
all applicable SNUR notification requirements and wait until all TSCA 
prerequisites for the commencement of manufacture or processing have 
been satisfied.
    Issuance of a SNUR for a chemical substance does not signify that 
the chemical substance is listed on the TSCA Chemical Substance 
Inventory (TSCA Inventory). Guidance on how to determine if a chemical 
substance is on the TSCA Inventory is available on the internet at 
<a href="https://www.epa.gov/tsca-inventory">https://www.epa.gov/tsca-inventory</a>.

C. Important Information About SNUN Submissions

1. SNUN Submissions
    SNUNs must be submitted on EPA Form No. 7710-25, generated using e-
PMN software, and submitted to the Agency in accordance with the 
procedures set forth in 40 CFR 720.40 and 721.25. E-PMN software is 
available electronically at <a href="https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca">https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca</a>.
2. Development and Submission of Information
    EPA recognizes that TSCA section 5 does not require development of 
any particular new information (e.g., generating test data) before 
submission of a SNUN. There is an exception: If a person is required to 
submit information for a chemical substance pursuant to a rule, order 
or consent agreement under TSCA section 4, then TSCA section 5(b)(1)(A) 
requires such information to be submitted to EPA at the time of 
submission of the SNUN.
    In the absence of a rule, TSCA order, or consent agreement under 
TSCA section 4 covering the chemical substance, persons are required 
only to submit information in their possession or control and to 
describe any other information known to or reasonably ascertainable by 
them (see 40 CFR 720.50). However, upon review of PMNs and SNUNs, the 
Agency has the authority to require appropriate testing. To assist with 
EPA's analysis of the SNUN, submitters are encouraged, but not 
required, to provide the potentially useful information as identified 
for the chemical substance in Unit III.C. of the proposed rule.
    EPA strongly encourages persons, before performing any testing, to 
consult with the Agency pertaining to protocol selection. Furthermore, 
pursuant to TSCA section 4(h), which pertains to reduction of testing 
in vertebrate animals, EPA encourages consultation with the Agency on 
the use of alternative test methods and strategies (also called New 
Approach Methodologies, or NAMs), if available, to generate the 
recommended test data. EPA encourages dialog with Agency 
representatives to help determine how best the submitter can meet both 
the data needs and the objective of TSCA section 4(h). For more 
information on alternative test methods and strategies to reduce 
vertebrate animal testing, visit <a href="https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/alternative-test-methods-and-strategies-reduce">https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/alternative-test-methods-and-strategies-reduce</a>.
    The potentially useful information described in Unit III. of the 
proposed rule may not be the only means of providing information to 
evaluate the chemical substance associated with the significant new 
uses. However, submitting a SNUN without any test data may increase the 
likelihood that

[[Page 69706]]

EPA will take action under TSCA sections 5(e) or 5(f). EPA recommends 
that potential SNUN submitters contact EPA early enough so that they 
will be able to conduct the appropriate tests.
    SNUN submitters should be aware that EPA will be better able to 
evaluate SNUNs which provide detailed information about human exposure 
and environmental release that may result from the significant new use 
of the chemical substances.

D. Public Comments on Proposed Rule and EPA Responses

    EPA received public comments on the proposed SNURs and prepared a 
Response to Comment document that provides the Agency responses. The 
comments and the Response to Comment document are available in the 
docket. As described in the Response to Comment document, EPA is 
finalizing these SNURs or has already finalized a SNUR in a separate 
action as proposed.

III. Chemical Substances Subject to These SNURs

A. What is the designated cutoff date for ongoing uses?

    EPA designates the date of publication of the proposed rule as the 
cutoff date for determining whether the new use is ongoing, i.e., June 
5, 2026 (91 FR 34480 (FRL-13126-01-OCSPP)). This designation is 
explained in more detail in Unit II.B.

B. What information was provided for each chemical substance?

    In Unit III.C. of the proposed rule, EPA provided the following 
information for each chemical substance subject to these SNURs:
    <bullet> PMN number (the CFR citation assigned in the regulatory 
text section of this document).
    <bullet> Chemical name (generic name, if the specific name is 
claimed as CBI).
    <bullet> Chemical Abstracts Service Registry Number (CASRN) or 
Accession Number (if assigned, for confidential chemical identities).
    <bullet> Basis for the SNUR (e.g., effective date of and basis for 
the TSCA Order).
    <bullet> Potentially useful information.
    The regulatory text section of this document specifies the chemical 
substances and activities designated as significant new uses. Certain 
new uses, including production volume limits and other uses designated, 
may be claimed as CBI, as discussed in more detail in Unit II.C. of the 
proposed rule.
    In addition, as discussed in Unit III.B. of the proposed rule, 
these SNURs include PMN substances that are subject to orders issued 
under TSCA section 5(e)(1)(A), as required by the determinations made 
under TSCA section 5(a)(3)(B). Those TSCA Orders require protective 
measures to limit exposures or otherwise mitigate the potential 
unreasonable risk. As such, the SNURs identify as significant new uses 
any manufacturing, processing, use, distribution in commerce, or 
disposal that does not conform to the restrictions imposed by the 
underlying TSCA Orders, consistent with TSCA section 5(f)(4).

IV. Statutory and Executive Order Reviews

    Additional information about these statutes and Executive orders 
can be found at <a href="https://www.epa.gov/laws-regulations">https://www.epa.gov/laws-regulations</a>.

A. Executive Order 12866: Regulatory Planning and Review

    This action establishes SNURs for new chemical substances that were 
the subject of PMNs. The Office of Management and Budget (OMB) has 
exempted these types of actions from review under Executive Order 12866 
(58 FR 51735, October 4, 1993).

B. Executive Order 14192: Unleashing Prosperity Through Deregulation

    Executive Order 14192 (90 FR 9065, February 6, 2025) does not apply 
because a significant new use rule for a new chemical under TSCA 
section 5 is exempt from review under Executive Order 12866.

C. Paperwork Reduction Act (PRA)

    According to the PRA (44 U.S.C. 3501 et seq.), an agency may not 
conduct or sponsor, and a person is not required to respond to a 
collection of information that requires OMB approval under PRA, unless 
it has been approved by OMB and displays a currently valid OMB control 
number. The OMB control numbers for EPA's regulations in title 40 of 
the CFR, after appearing in the Federal Register, are listed in 40 CFR 
part 9, and included on the related collection instrument or form, if 
applicable.
    The information collection requirements related to SNURs have 
already been approved by OMB pursuant to PRA under OMB control number 
2070-0038 (EPA ICR No. 1188). This action does not impose any burden 
requiring additional OMB approval. If an entity were to submit a SNUN 
to the Agency, the annual burden is estimated to average between 30 and 
170 hours per submission. This burden estimate includes the time needed 
to review instructions, search existing data sources, gather and 
maintain the data needed, and complete, review, and submit the required 
SNUN.

D. Regulatory Flexibility Act (RFA)

    I certify that this action will not have a significant economic 
impact on a substantial number of small entities under the RFA (5 
U.S.C. 601 et seq.). The requirement to submit a SNUN applies to any 
person (including small or large entities) who intends to engage in any 
activity described in the final rule as a ``significant new use.'' 
Because these uses are ``new,'' based on all information currently 
available to EPA, EPA has concluded that no small or large entities 
presently engage in such activities.
    A SNUR requires that any person who intends to engage in such 
activity in the future must first notify EPA by submitting a SNUN. 
Although some small entities may decide to pursue a significant new use 
in the future, EPA cannot presently determine how many, if any, there 
may be. However, EPA's experience to date is that, in response to the 
promulgation of SNURs covering over 1,000 chemicals, the Agency 
receives only a small number of notices per year. For example, the 
number of SNUNs received was 7 in Federal fiscal year (FY) 2020, 9 in 
FY2021, 9 in FY2022, 23 in FY2023, and 7 in FY2024, and only a fraction 
of these submissions were from small businesses.
    In addition, the Agency currently offers relief to qualifying small 
businesses by reducing the SNUN submission fee from $37,000 to $6,480. 
This lower fee reduces the total reporting and recordkeeping cost of 
submitting a SNUN to about $14,500 per SNUN submission for qualifying 
small firms. Therefore, the potential economic impacts of complying 
with these proposed SNURs are not expected to be significant or 
adversely impact a substantial number of small entities. In a SNUR that 
published in the Federal Register of June 2, 1997 (62 FR 29684 (FRL-
5597-1)), the Agency presented its general determination that SNURs are 
not expected to have a significant economic impact on a substantial 
number of small entities, which was provided to the Chief Counsel for 
Advocacy of the Small Business Administration.

E. Unfunded Mandates Reform Act (UMRA)

    This action does not contain an unfunded mandate of $100 million or 
more (in 1995 dollars) in any one year as described in UMRA, 2 U.S.C. 
1531-1538, and does not significantly or uniquely affect small 
governments.

[[Page 69707]]

Based on EPA's experience with proposing and finalizing SNURs, State, 
local, and Tribal governments have not been impacted by SNURs, and EPA 
does not have any reasons to believe that any State, local, or Tribal 
government will be impacted by these SNURs. In addition, the estimated 
costs of this action to the private sector do not exceed $183 million 
or more in any one year (the 1995 dollars are adjusted to 2023 dollars 
for inflation using the GDP implicit price deflator). The estimated 
costs for this action are discussed in Unit I.D.

F. Executive Order 13132: Federalism

    This action will not have federalism implications as specified in 
Executive Order 13132 (64 FR 43255, August 10, 1999), because it is not 
expected to have a substantial direct effect on States, on the 
relationship between the national government and the States, or on the 
distribution of power and responsibilities among the various levels of 
government. Accordingly, the requirements of Executive Order 13132 do 
not apply to this action.

G. Executive Order 13175: Consultation and Coordination With Indian 
Tribal Governments

    This action will not have Tribal implications as specified in 
Executive Order 13175 (65 FR 67249, November 9, 2000), because it is 
not expected to have substantial direct effects on Indian Tribes, 
significantly or uniquely affect the communities of Indian Tribal 
governments and does not involve or impose any requirements that affect 
Indian Tribes. Accordingly, the requirements of Executive Order 13175 
do not apply to this action.

H. Executive Order 13045: Protection of Children From Environmental 
Health Risks and Safety Risks

    This action is not subject to Executive Order 13045 (62 FR 19885, 
April 23, 1997), because it does not concern an environmental health or 
safety risk. Since this action does not concern a human health risk, 
EPA's 2026 Policy on Children's Health also does not apply. Although 
the establishment of these SNURs do not address an existing children's 
environmental health concern because the chemical uses involved are not 
ongoing uses, SNURs require that persons notify EPA at least 90 days 
before commencing manufacture (defined by statute to include import) or 
processing of the identified chemical substances for an activity that 
is designated as a significant new use by the SNUR. This notification 
allows EPA to assess the intended uses to identify potential risks and 
take appropriate actions before the activities commence.

I. Executive Order 13211: Actions Concerning Regulations That 
Significantly Affect Energy Supply, Distribution, or Use

    This action is not a ``significant energy action'' as defined in 
Executive Order 13211 (66 FR 28355, May 22, 2001), because it is not 
likely to have a significant adverse effect on the supply, 
distribution, or use of energy.

J. National Technology Transfer and Advancement Act (NTTAA)

    This action does not involve any technical standards subject to 
NTTAA section 12(d) (15 U.S.C. 272 note).

K. Congressional Review Act (CRA)

    This action is subject to the CRA (5 U.S.C. 801 et seq.), and EPA 
will submit a rule report to each House of the Congress and to the 
Comptroller General of the United States. This action is not a ``major 
rule'' as defined by 5 U.S.C. 804(2).

List of Subjects in 40 CFR Part 721

    Environmental protection, Chemicals, Hazardous substances, 
Reporting and recordkeeping requirements.

    Dated: October 28, 2026.
Mary Elissa Reaves,
Director, Office of Pollution Prevention and Toxics.

    For the reasons stated in the preamble, 40 CFR chapter I is amended 
as follows:

PART 721--SIGNIFICANT NEW USES OF CHEMICAL SUBSTANCES

0
1. The authority citation for part 721 continues to read as follows:

    Authority: 15 U.S.C. 2604, 2607, and 2625(c).


0
2. Add Sec. Sec.  721.12225 through 721.12228 and Sec. Sec.  721.12230 
through 721.12259 to subpart E to read as follows:
* * * * *
Sec.
721.12225 Alcohols, C16-18 and C18-unsatd., reaction products with 
substituted alkyloxirane and alkyl acid (generic).
721.12226 Manganate(4-), hexakis(cyano-.kappa.C)-, manganese(2+) 
sodium, (OC-6-11)-.
721.12227 Ferrate(4-), hexakis(cyano-.kappa.C)-, iron(3+) 
manganese(2+) sodium, (OC-6-11)-.
721.12228 1H,4H,14H,17H-2,16:3,15-Dimethano-
5H,6H,7H,8H,9H,10H,11H,12H,13H,18H,19H,20H,21H,22H,23H,24H,25H,26H-
2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,15,16,17a,18a,19a,20a,21a,22a,2
3a,24a,25a,26a-
tetracosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta[1'',2'',3'':
3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-
g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-
1,4,6,8,10,12,14,17,19,21,23,25-dodecone, dodecahydro-, 
stereoisomer; 2,18:3,17-Dimethano-
2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a,20a,21a,22a,2
3a,24a,25a,26a,27a,28a,29a,30a-
octacosaazabispentaleno[1''''',6''''':5'''', 
6'''',7'''']cycloocta[1'''',2'''',3'''':3''',4''']pentaleno[1''',6'''
:5'',6'',7'']cycloocta[1'',2'',3'':3',4']pentaleno[1',6':5,6,7]cycloo
cta[1,2,3-cd:1',2',3'-gh]pentalene-
1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, 
stereoisomer; 2,20:3,19-Dimethano-
2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,16a,17a,19,20,21a,22a,2
3a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-
dotriacontaazabispentaleno[1''''',6''''':5'''',6'''',7'''']cycloocta[
1'''',2'''',3'''':3''',4''']pentaleno[1''',6''':5'',6'',7'']cycloocta
[1'',2'',3'':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-
gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-
1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, 
hexadecahydro-, stereoisomer.
* * * * *
721.12230 Mixed metal oxide (generic).
721.12231 Rosin, fumarated, polymer with adipic acid and glycerol.
721.12232 Derivatives of fats and oils, plant based, polycyclic 
acids functionalized, aromatic acids, polyester with diols and 
triols (generic).
721.12233 Multi-walled carbon nanotubes.
721.12234 Polysubstitutedcarbocycle, polyhydroxy, polyalkyl 
(generic).
721.12235 Cashew, nutshell liq., polymer with epichlorohydrin and 
glycol (generic).
721.12236 Fatty acids, reaction products with alkene polyamine 
(generic).
721.12237 Fatty acids, reaction products with alkene polyamine 
(generic).
721.12238 Fatty acids, reaction products with alkene polyamine 
(generic).
721.12239 Functionalized fatty acids, reaction products with alkene 
polyamines (generic).
721.12240 Functionalized fatty acids, reaction products with alkene 
polyamines (generic).
721.12241 Substitutedheterocyclic onium compound, salt with 
fluoropolysubstitutedalkyl substitutedtricycloalkane carboxylate 
(1:1), polymer with 4-ethenyl-2-methoxylphenol and 
fluorosubstitutedaromaticalkyl 2-methyl-2-propenoate, di-Me 2,2'-
(1,2-diazenediyl)bis[2- methylpropanoate]-initiated (generic).
721.12242 Dibenzothiophenium, 5-phenyl-, salt with 
fluoroheterosubstitutedalkyl

[[Page 69708]]

heterosubstitutedhalosubstitutedaromatichydrocarboncarboxylate 
(1:1), polymer with 3- ethenylphenol and fluorocarbomonocyclealkyl 
2-methyl-2-propenoate (generic).
721.12243 Dibenzothiophenium, 5-phenyl-, salt with 
fluoroheterosubstitutedalkyl 
heterosubstitutedhalosubstitutedaromatichydrocarboncarboxylate 
(1:1), polymer with 3- ethenylphenol and alkylcycloalkyl 2-methyl-2-
propenoate (generic).
721.12244 Lithium dihalo (oxalato)borate(1-) (generic).
721.12245 Carbamodithioic acid, N,N-bis(phenylmethyl)-, compd. with 
2,2'-dithiobis[ethanamine] (2:1).
721.12246 Benzene, [alkyl [polycycloalkyl]-yl] polyfluoro-alkyl- 
(generic).
721.12247 Substituted polyphenyl, alkyl-fluoro-alky (generic).
721.12248 Substituted polyphenyl, alkyl-polyfluoro-alkyl- (generic).
721.12249 Substituted polyphenyl, alkyl-alkyl-polyfluoro- (generic).
721.12250 Substituted polyphenyl, alkyl-alkyl-fluoro- (generic).
721.12251 Phenyl carboxylic acid, alkylcycloalkyl, phenylalkanediyl 
ester (generic).
721.12252 Fluoro substituted polyphenyl alkyl (generic).
721.12253 Polyphenyl, ethoxy-polyfluoro-alkyl- (generic).
721.12254 Transition metal polykis (heteroatom substituted 
carbomonocycle), hydroxy- oxo-(generic).
721.12255 Heteromonocyclealkanol, homopolymer, monoalkyl ether 
(generic).
721.12256 Sulfonium, bis(dihalo carbomonocycle)carbomonocycle-. salt 
with dihalo-sulfoalkyl [(alkenylcarbomonocycle)substituted] 
trisubstituted benzoate, polymer with alkenylcarbomonocycle and 
alkylcarbomonocycle alkyl alkenoate (generic).
721.12257 Sulfonium, bis(dihalo carbomonocycle)(halo 
carbomonocycle)-, salt with dihalo-sulfoalkyl 
[(alkenylcarbomonocycle)substituted] trisubstituted benzoate, 
polymer with alkenylcarbomonocycle and alkylcarbomonocycle alkyl 
alkenoate (generic).
721.12258 Sulfonium, bis(dihalo carbomonocycle)(halocarbomonocycle)-
, salt with trihalobenzoate (generic).
721.12259 Aromatic sulfonium tricyclo salt with carbopolycycloalkyl 
ester polysubstitutedarylhetero-acid (generic).
* * * * *


Sec.  721.12225  Alcohols, C16-18 and C18-unsatd., reaction products 
with substituted alkyloxirane and alkyl acid (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
alcohols, C16-18 and C18-unsatd., reaction products with substituted 
alkyloxirane and alkyl acid (PMN P-21-76) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (a)(3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1) and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: skin sensitization and specific 
target organ toxicity. Alternative hazard and warning statements that 
meet the criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12226  Manganate(4-), hexakis(cyano-.kappa.C)-, manganese(2+) 
sodium, (OC-6-11)-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as manganate(4-), 
hexakis(cyano-.kappa.C)-, manganese(2+) sodium, (OC-6-11)- (PMN P-22-
40; CAS No. 2073840-04-5) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section. The requirements of this section do not apply to quantities of 
the substance after they have been incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3) through (6), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 1000.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: acute 
toxicity, skin sensitization, reproductive toxicity, and specific 
target organ toxicity. Alternative hazard and warning statements that 
meet the criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(b) and (c). For purposes of Sec.  
721.80(b) and (c), the process remains enclosed as long as the only 
releases are from sampling, dust filter changes, loss of integrity or 
failure of the manufacturing process equipment or control systems. It 
is a significant new use to use the substance other than as a component 
in manufacture of high-performance batteries. It is a significant new 
use to use the substance in any manner that results in inhalation 
exposure to workers. It is a significant new use to perform the dust 
filter change more than two times a year. It is a significant new use 
to manufacture the substance at a site that has off-gas waste streams 
unless all such waste streams are captured and routed through 
engineering controls that achieve a total combined efficiency of 99.9% 
destruction of the substance. It is a significant new use to 
manufacture the substance unless the concentration of manganese does 
not exceed the confidential percentage by weight listed in the Order.
    (iv) Disposal. It is a significant new use to dispose of the 
substance, when not in solid form, by landfill. The substance may be 
disposed of by landfill at hazardous waste landfill facilities that are 
in compliance with RCRA subtitle C and D, when in solid form. The 
substance or waste streams containing the substance must be disposed of 
by incineration, when not in solid form. It is a significant new use to 
exceed the confidential disposal by incineration limit listed in the 
Order. This limit does

[[Page 69709]]

not apply to quantities sent for incineration at a hazardous waste 
incineration facility that is compliant with RCRA subtitle C.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N=0.2.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12227   Ferrate(4-), hexakis(cyano-.kappa.C)-, iron(3+) 
manganese(2+) sodium, (OC-6-11)-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as ferrate(4-), 
hexakis(cyano-.kappa.C)-, iron(3+) manganese(2+) sodium, (OC-6-11)- 
(PMN P-22-41; CAS No. 2073839-30-0) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section. The requirements of this section do not apply to 
quantities of the substance after they have been incorporated into an 
article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3) through (6), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 10.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: acute 
toxicity, skin sensitization, reproductive toxicity, and specific 
target organ toxicity. Alternative hazard and warning statements that 
meet the criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(b) and (c). For purposes of Sec.  
721.80(b) and (c), the process remains enclosed as long as the only 
releases are from sampling, dust filter changes, loss of integrity or 
failure of the manufacturing process equipment or control systems. It 
is a significant new use to use the substance other than as a component 
in manufacture of high-performance batteries. It is a significant new 
use to use the substance in any manner that results in inhalation 
exposure to workers. It is a significant new use to perform the dust 
filter change more than two times a year. It is a significant new use 
to manufacture the substance at a site that has off-gas waste streams 
unless all such waste streams are captured and routed through 
engineering controls that achieve a total combined efficiency of 99.9% 
destruction of the substance. It is a significant new use to 
manufacture the substance unless the concentration of manganese does 
not exceed the confidential percentage by weight listed in the Order.
    (iv) Disposal. It is a significant new use to dispose of the 
substance, when not in solid form, by landfill. The substance may be 
disposed of by landfill at hazardous waste landfill at a facility that 
is in compliance with RCRA subtitle C and D, when in solid form. The 
substance or waste streams containing the substance must be disposed of 
by incineration, when not in solid form. It is a significant new use to 
exceed the confidential disposal by incineration limit listed in the 
Order. This limit does not apply to quantities sent for incineration at 
a hazardous waste incineration facility that is compliant with RCRA 
subtitle C.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N = 2.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section
    except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12228   1H,4H,14H,17H-2,16:3,15-Dimethano-
5H,6H,7H,8H,9H,10H,11H,12H,13H,18H,19H,20H,21H,22H,23H,24H,25H,26H-
2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,15,16,17a,18a,19a,20a,21a,22a,23a,
24a,25a,26a-
tetracosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta[1'',2'',3'':3',
4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-
g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-
1,4,6,8,10,12,14,17,19,21,23,25-dodecone, dodecahydro-, stereoisomer; 
2,18:3,17-Dimethano-
2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a,20a,21a,22a,23a,
24a,25a,26a,27a,28a,29a,30a-
octacosaazabispentaleno[1''''',6''''':5'''',6'''',7'''']cycloocta[1'''',
2'''',3'''':3''',4''']pentaleno[1''',6''':5'',6'',7'']cycloocta[1'',2'',
3'':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-
gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, 
tetradecahydro-, stereoisomer; 2,20:3,19-Dimethano-
2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,16a,17a,19,20,21a,22a,23a,
24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-
dotriacontaazabispentaleno[1''''',6''''':5'''',6'''',7'''']cycloocta[1''
'',2'''',3'''':3''',4''']pentaleno[1''',6''':5'',6'',7'']cycloocta[1'',2
'',3'':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-
g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-
1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, 
stereoisomer.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified as 1H,4H,14H,17H-
2,16:3,15-dimethano-
5H,6H,7H,8H,9H,10H,11H,12H,13H,18H,19H,20H,21H,22H,23H,24H,25H,26H-
2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,15,16,17a,18a,19a,20a,21a,22a,23a,
24a,25a,26a-
tetracosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta[1'',2'',3'':3',
4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-
g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-
1,4,6,8,10,12,14,17,19,21,23,25-dodecone, dodecahydro-, stereoisomer; 
2,18:3,17-dimethano-
2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a,20a,21a,22a,23a,
24a,25a,26a,27a,28a,29a,30a-
octacosaazabispentaleno[1''''',6''''':5'''', 
6'''',7'''']cycloocta[1'''',2'''',3'''':3''',4''']pentaleno[1''',6''':5'
',6'',7'']cycloocta[1'',2'',3'':3',4']pentaleno[1',6':5,6,7]cycloocta[1,
2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-
tetradecone, tetradecahydro-, stereoisomer; 2,20:3,19-dimethano-
2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,16a,17a,19,20,21a,22a,23a,
24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-
dotriacontaazabispentaleno[1''''',6''''':5'''',6'''',7'''']cycloocta[1''
'',2'''',3'''':3''',4''']pentaleno[1''',6''':5'',6'',7'']cycloocta[1'',2
'',3'':3',4']pentaleno

[[Page 69710]]


[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-
c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-
hexadecone, hexadecahydro-, stereoisomer (PMN P-22-158; CASRNs 283175-
97-3; 259886-50-5; 259886-51-6) are subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section. The requirements of this section do not apply to 
quantities of the substances after they have been incorporated into a 
polymer matrix, or when incorporated into a consumer product at or 
below 1.7% by weight (calculated by the weight of all three substances 
combined) and packaged as a consumer product.
    (2) The significant new uses are:
    (i) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(3)(iii), and (g)(5). Alternative hazard 
and warning statements that meet the criteria of the Globally 
Harmonized System and OSHA Hazard Communication Standard may be used.
    (ii) Industrial, commercial, and consumer activities. It is a 
significant new use to process for use or use the substances in a 
consumer product unless the concentration of the substances combined 
does not exceed 1.7% by weight in the consumer product.
    (iii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) where N = 18.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (c), (f) through (i), and (k) are applicable to 
manufacturers, importers, and processors of these substances.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
* * * * *


Sec.  721.12230  Mixed metal oxide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as mixed 
metal oxide (PMNs P-22-187 and P-24-88; Accession No. 303027) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been entrained in cured coating.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3) through (6), (b), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 10.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f), (g)(1) and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: specific target organ toxicity 
and carcinogenicity. Alternative hazard and warning statements that 
meet the criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance in a 
solid form other than when using dust controls with a capture and 
control efficiency of >97%.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (j) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12231  Rosin, fumarated, polymer with adipic acid and 
glycerol.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as rosin, fumarated, 
polymer with adipic acid and glycerol (PMN P-23-96; CASRN 2888640-13-7) 
is subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: eye 
irritation and skin sensitization. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o).
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) where N = 330.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12232  Derivatives of fats and oils, plant based, polycyclic 
acids functionalized, aromatic acids, polyester with diols and triols 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
derivatives of fats and oils, plant based, polycyclic acids 
functionalized, aromatic acids, polyester with diols and triols (PMN P-
23-99) is subject to reporting under this section for the significant 
new uses described in paragraph (a)(2) of this section. The 
requirements of this section do not apply to quantities of the 
substance after they have been completely reacted or cured.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3) through (6), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health

[[Page 69711]]

(NIOSH) assigned protection factor (APF) of at least 10.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: skin 
irritation, eye irritation, skin sensitization, reproductive toxicity, 
and specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to use the 
substance in spray applications.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N = 21. For purposes of 
721.91(a)(7), the control technology is primary and secondary 
wastewater treatment as defined in 40 CFR part 133 and the percentage 
removal of the substance resulting from use of the specified control 
technology is 90%.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12233  Multi-walled carbon nanotubes.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as multi-walled carbon 
nanotubes (PMN P-23-105) is subject to reporting under this section for 
the significant new uses described in paragraph (a)(2) of this section. 
The requirements of this section do not apply to quantities of the 
substance after they have been completely entrained or incorporated 
into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3) through (6), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 1,000.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: eye 
irritation, skin sensitization, respiratory sensitization, specific 
target organ toxicity, reproductive toxicity, genetic toxicity, and 
carcinogenicity. Alternative hazard and warning statements that meet 
the criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (k), (o), and (t). It is a significant 
new use to manufacture, process, or use the substance in solid form 
unless using engineering controls with a minimum efficiency of 95% 
capture and 99% control. Engineering controls are not needed when the 
substance is in liquid solution or dispersion. It is a significant new 
use to manufacture, process, or use the substance unless the 
confidential residual listed in the Order is present at the 
confidential limit listed in the Order or less by weight.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12234   Polysubstitutedcarbocycle, polyhydroxy, polyalkyl 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
polysubstitutedcarbocycle, polyhydroxy, polyalkyl (PMN P-23-156) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3) through (6), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 50, or 1,000 if spray 
applied.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: respiratory 
sensitization, skin sensitization, and specific target organ toxicity. 
Alternative hazard and warning statements that meet the criteria of the 
Globally Harmonized System and OSHA Hazard Communication Standard may 
be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f). It is a significant new use to process 
for use or use the substance in a consumer product where the 
concentration of the substance is equal to or exceeds the confidential 
percentage in formulation listed in the Order.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) where N = 19.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12235  Cashew, nutshell liq., polymer with epichlorohydrin 
and glycol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as cashew, 
nutshell liq., polymer with epichlorohydrin and glycol (PMN P-24-45) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after

[[Page 69712]]

they have been completely reacted or cured.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3) through (6), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 50.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: skin irritation, eye 
irritation, reproductive toxicity, and specific target organ toxicity. 
Alternative hazard and warning statements that meet the criteria of the 
Globally Harmonized System and OSHA Hazard Communication Standard may 
be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to spray 
apply the substance.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12236  Fatty acids, reaction products with alkene polyamine 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as fatty 
acids, reaction products with alkene polyamine (PMN P-24-54) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: eye 
corrosion, skin corrosion, skin sensitization, and specific target 
organ toxicity. Alternative hazard and warning statements that meet the 
criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure to the substance.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12237  Fatty acids, reaction products with alkene polyamine 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as fatty 
acids, reaction products with alkene polyamine (PMN P-24-55) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: eye 
corrosion, skin corrosion, skin sensitization, and specific target 
organ toxicity. Alternative hazard and warning statements that meet the 
criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure to the substance.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12238  Fatty acids, reaction products with alkene polyamine 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as fatty 
acids, reaction products with alkene polyamine (PMN P-24-56) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: eye 
corrosion, skin corrosion, skin sensitization, and specific target 
organ toxicity. Alternative hazard and warning

[[Page 69713]]

statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure to the substance.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12239  Functionalized fatty acids, reaction products with 
alkene polyamines (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
functionalized fatty acids, reaction products with alkene polyamines 
(PMN P-24-58) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: acute 
toxicity, serious eye damage, skin corrosion, skin sensitization, and 
specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure to the substance.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12240  Functionalized fatty acids, reaction products with 
alkene polyamines (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
functionalized fatty acids, reaction products with alkene polyamines 
(PMN P-24-59) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: acute 
toxicity, serious eye damage, skin corrosion, skin sensitization, and 
specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure to the substance.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12241  Substituted heterocyclic onium compound, salt with 
fluoropolysubstitutedalkyl substitutedtricycloalkane carboxylate (1:1), 
polymer with 4-ethenyl-2-methoxylphenol and 
fluorosubstitutedaromaticalkyl 2-methyl-2-propenoate, di-Me 2,2'-(1,2-
diazenediyl)bis[2-methylpropanoate]-initiated (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substitutedheterocyclic onium compound, salt with 
fluoropolysubstitutedalkyl substitutedtricycloalkane carboxylate (1:1), 
polymer with 4-ethenyl-2-methoxylphenol and 
fluorosubstitutedaromaticalkyl 2-methyl-2-propenoate, di-Me 2,2'-(1,2-
diazenediyl)bis[2-methylpropanoate]-initiated (PMN P-24-98) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section. The requirements of this section 
do not apply to quantities of the substance after they have been 
completely reacted or adhered (during photolithographic processes) onto 
a semiconductor wafer surface or similar manufactured article used in 
the production of semiconductor technologies.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining 
which persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), 
(g)(3)(i) and (ii), and (g)(5). For purposes of Sec.  721.72(e), the 
concentration is set at 1.0% by weight or volume. For purposes of Sec.  
721.72(g)(1), this substance may cause: acute toxicity, skin 
irritation, serious eye damage, skin sensitization, genetic

[[Page 69714]]

toxicity, and specific target organ toxicity. Alternative hazard and 
warning statements that meet the criteria of the Globally Harmonized 
System and OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (k), and (t). It is a significant new 
use to import the substance other than in solution unless in sealed 
containers weighing 5 kilograms or less. It is a significant new use to 
process the substance in any way that generates vapor, dust, mist, or 
aerosol in a non-enclosed process. It is a significant new use to 
manufacture the substance longer than 9 months.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12242  Dibenzothiophenium, 5-phenyl-, salt with fluorohetero 
substituted alkyl hetero substituted halo substituted 
aromatichydrocarboncarboxylate (1:1), polymer with 3-ethenylphenol and 
fluorocarbomonocyclealkyl 2-methyl-2-propenoate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
dibenzothiophenium, 5-phenyl-, salt with fluoroheterosubstituted alkyl 
hetero substituted halo substituted aromatichydrocarboncarboxylate 
(1:1), polymer with 3- ethenylphenol and fluorocarbomonocyclealkyl 2-
methyl-2-propenoate (PMN P-25-60) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section. The requirements of this section do not apply to 
quantities of the substance after they have been completely reacted or 
adhered (during photolithographic processes) onto a semiconductor wafer 
surface or similar manufactured article used in the production of 
semiconductor technologies.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining 
which persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), 
(g)(3)(i) and (ii), and (g)(5). For purposes of Sec.  721.72(e), the 
concentration is set at 1.0% by weight or volume. For purposes of Sec.  
721.72(g)(1), this substance may cause: acute toxicity, skin 
irritation, serious eye damage, skin sensitization, genetic toxicity, 
and specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (k), and (t). It is a significant new 
use to import the substance other than in solution unless in sealed 
containers weighing 5 kilograms or less. It is a significant new use to 
process the substance in any way that generates vapor, dust, mist, or 
aerosol in a non-enclosed process. It is a significant new use to 
manufacture the substance longer than 9 months.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12243  Dibenzothiophenium, 5-phenyl-, salt with 
fluoroheterosubstitutedalkyl hetero substituted halo substituted 
aromatichydrocarboncarboxylate (1:1), polymer with 3-ethenylphenol and 
alkylcycloalkyl 2-methyl-2-propenoate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
dibenzothiophenium, 5-phenyl-, salt with fluoroheterosubstitutedalkyl 
hetero substituted halo substituted aromatichydrocarboncarboxylate 
(1:1), polymer with 3- ethenylphenol and alkylcycloalkyl 2-methyl-2-
propenoate (PMN P-25-64) is subject to reporting under this section for 
the significant new uses described in paragraph (a)(2) of this section. 
The requirements of this section do not apply to quantities of the 
substance after they have been completely reacted or adhered (during 
photolithographic processes) onto a semiconductor wafer surface or 
similar manufactured article used in the production of semiconductor 
technologies.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining 
which persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), 
(g)(3)(i) and (ii), and (g)(5). For purposes of Sec.  721.72(e), the 
concentration is set at 1.0% by weight or volume. For purposes of Sec.  
721.72(g)(1), this substance may cause: acute toxicity, skin 
irritation, serious eye damage, skin sensitization, genetic toxicity, 
and specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (k), and (t). It is a significant new 
use to import the substance other than in solution unless in sealed 
containers weighing 5 kilograms or less. It is a significant new use to 
process the substance in any way that generates vapor, dust, mist, or 
aerosol in a non-enclosed process. It is a significant new use to 
manufacture the substance longer than 9 months.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12244  Lithium dihalo (oxalato)borate(1-) (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified

[[Page 69715]]

generically as lithium dihalo (oxalato)borate(1-) (PMN P-24-109) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been sealed in a battery.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3) through (6), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 10.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: acute 
toxicity, skin irritation, skin sensitization, serious eye damage, 
reproductive toxicity, and specific target organ toxicity. Alternative 
hazard and warning statements that meet the criteria of the Globally 
Harmonized System and OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o).
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N=1.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12245  Carbamodithioic acid, N,N-bis(phenylmethyl)-, compd. 
with 2,2'-dithiobis[ethanamine] (2:1).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as carbamodithioic 
acid, N,N-bis(phenylmethyl)-, compd. with 2,2'-dithiobis[ethanamine] 
(2:1) (PMN P-24-112; CAS No. 239446-62-9) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section. The requirements of this section do not apply to 
quantities of the substance when completely reacted or cured.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3) through (6), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 10.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: acute 
toxicity, skin sensitization, reproductive toxicity, and specific 
target organ toxicity. Alternative hazard and warning statements that 
meet the criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to 
manufacture the substance other than by import in a pellet form into 
the United States (i.e., no domestic manufacture).
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) (k) are applicable to manufacturers, importers, 
and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12246  Benzene, [alkyl [polycycloalkyl]-yl] polyfluoro-alkyl- 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
benzene, [alkyl [polycycloalkyl]-yl] polyfluoro-alkyl- (PMN P-24-146) 
is subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance when sealed inside 
a display.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: specific target organ toxicity. 
Alternative hazard and warning statements that meet the criteria of the 
Globally Harmonized System and OSHA Hazard Communication Standard may 
be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k). It is a significant new use to 
manufacture, process, or use the substance other than in a liquid 
solution.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12247  Substituted polyphenyl, alkyl-fluoro-alky (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted polyphenyl, alkyl-fluoro-alky (PMN P-24-148) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section. The requirements of this section do 
not apply to quantities of the substance after they have been 
incorporated into an article.
    (2) The significant new uses are:

[[Page 69716]]

    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1) and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: reproductive toxicity and 
specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that generates 
a vapor, mist, dust, or aerosol containing the substance.
    (iv) Disposal. It is a significant new use to dispose of the 
substance, or waste streams containing the substance, by incineration 
other than by hazardous waste incineration in compliance with RCRA 
subtitle C, incineration above 1,000 degrees C for at least two 
seconds.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12248  Substituted polyphenyl, alkyl-polyfluoro-alkyl- 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted polyphenyl, alkyl-polyfluoro-alkyl (PMN P-24-149) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: reproductive toxicity and 
specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that generates 
a vapor, mist, dust, or aerosol containing the substance.
    (iv) Disposal. It is a significant new use to dispose of the 
substance, or waste streams containing the substance, by incineration 
other than by hazardous waste incineration in compliance with RCRA 
subtitle C, incineration above 1,000 degrees C for at least two 
seconds.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12249  Substituted polyphenyl, alkyl-alkyl-polyfluoro- 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted polyphenyl, alkyl-alkyl-polyfluoro- (PMN P-24-150) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: reproductive toxicity and 
specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that generates 
a vapor, mist, dust, or aerosol containing the substance.
    (iv) Disposal. It is a significant new use to dispose of the 
substance, or waste streams containing the substance, by incineration 
other than by hazardous waste incineration in compliance with RCRA 
subtitle C, incineration above 1,000 degrees C for at least two 
seconds.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12250  Substituted polyphenyl, alkyl-alkyl-fluoro- (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted polyphenyl, alkyl-alkyl-fluoro- (PMN P-24-151) is subject 
to reporting under this section

[[Page 69717]]

for the significant new uses described in paragraph (a)(2) of this 
section. The requirements of this section do not apply to quantities of 
the substance after they have been incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: reproductive toxicity and 
specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that generates 
a vapor, mist, dust, or aerosol containing the substance.
    (iv) Disposal. It is a significant new use to dispose of the 
substance, or waste streams containing the substance, by incineration 
other than by hazardous waste incineration in compliance with RCRA 
subtitle C, incineration above 1,000 degrees C for at least two 
seconds.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12251  Phenyl carboxylic acid, alkylcycloalkyl, 
phenylalkanediyl ester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as phenyl 
carboxylic acid, alkylcycloalkyl, phenylalkanediyl ester (PMN P-24-152) 
is subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: specific target organ toxicity. 
Alternative hazard and warning statements that meet the criteria of the 
Globally Harmonized System and OSHA Hazard Communication Standard may 
be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that generates 
a vapor, mist, dust, or aerosol containing the substance.
    (iv) Disposal. It is a significant new use to dispose of the 
substance, or waste streams containing the substance, by hazardous 
waste landfill other than at a facility that is in compliance with RCRA 
Subtitle C.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12252  Fluoro substituted polyphenyl alkyl (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as fluoro 
substituted polyphenyl alkyl (PMN P-24-153) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section. The requirements of this section do not apply 
to quantities of the substance after they have been incorporated into 
an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: reproductive toxicity and 
specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that generates 
a vapor, mist, dust, or aerosol containing the substance.
    (iv) Disposal. It is a significant new use to dispose of the 
substance, or waste streams containing the substance, by incineration 
unless hazardous waste incineration in compliance with RCRA Subtitle C, 
incineration above 1,000 degrees C for at least two seconds is used.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

[[Page 69718]]

Sec.  721.12253  Polyphenyl, ethoxy-polyfluoro-alkyl- (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
polyphenyl, ethoxy-polyfluoro-alkyl- (PMN P-24-154) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section. The requirements of this section do 
not apply to quantities of the substance after they have been 
incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: specific 
target organ toxicity. Alternative hazard and warning statements that 
meet the criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) and (o). It is a significant new use to 
manufacture, process, or use the substance in any manner that generates 
a vapor, mist, dust, or aerosol containing the substance.
    (iv) Disposal. It is a significant new use to dispose of the 
substance, or waste streams containing the substance, by incineration 
unless hazardous waste incineration in compliance with RCRA Subtitle C, 
incineration above 1,000 degrees C for at least two seconds is used.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12254  Transition metal polykis (heteroatom substituted 
carbomonocycle), hydroxy- oxo- (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
transition metal polykis (heteroatom substituted carbomonocycle), 
hydroxy- oxo- (PMN P-24-163) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section. The requirements of this section do not apply to quantities of 
the substance after they have been incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (3) through (6), and (c). When determining which persons 
are reasonably likely to be exposed as required for Sec.  721.63(a)(1) 
and (4), engineering control measures (e.g., enclosure or confinement 
of the operation, general and local ventilation) or administrative 
control measures (e.g., workplace policies and procedures) shall be 
considered and implemented to prevent exposure, where feasible. For 
purposes of Sec.  721.63(a)(5), respirators must provide a National 
Institute for Occupational Safety and Health (NIOSH) assigned 
protection factor (APF) of at least 1000 when the proportion of the 
substance with a particle size less than 10 microns is >0.1% (by 
weight). When the proportion of the substance with a particle size less 
than 10 microns is <=0.1% (by weight), the worker respirator 
requirement does not apply.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: specific target organ toxicity. 
Alternative hazard and warning statements that meet the criteria of the 
Globally Harmonized System and OSHA Hazard Communication Standard may 
be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12255  Heteromonocyclealkanol, homopolymer, monoalkyl ether 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
heteromonocyclealkanol, homopolymer, monoalkyl ether (PMN P-25-58) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For 
purposes of Sec.  721.72(g)(1), this substance may cause: skin 
irritation and specific target organ toxicity. Alternative hazard and 
warning statements that meet the criteria of the Globally Harmonized 
System and OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k). It is a significant new use to 
manufacture, process for use or use the substance in any manner that 
results in inhalation exposure to the substance.
    (iv) Disposal. Requirements as specified in Sec.  721.85(a)(1) 
through (3), (b)(1) through (3), and (c)(1) through (3). For purposes 
of Sec.  721.85(a)(2), (b)(2), and (c)(2), the landfill must be a 
hazardous waste landfill facility that is in compliance with subtitles 
C and D of the Resource Conservation and Recovery Act (RCRA).
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N = 140. For purposes of 
721.91(a)(7), the control technology is primary and secondary 
wastewater treatment as defined in 40 CFR part 133 and the percentage 
removal of the substance resulting from use of the specified control 
technology is 50%.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).

[[Page 69719]]

    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12256  Sulfonium, bis(dihalo carbomonocycle)carbomonocycle-. 
salt with dihalo-sulfoalkyl [(alkenylcarbomonocycle)substituted] 
trisubstituted benzoate, polymer with alkenylcarbomonocycle and 
alkylcarbomonocycle alkyl alkenoate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
sulfonium, bis(dihalo carbomonocycle)carbomonocycle-. salt with dihalo-
sulfoalkyl [(alkenylcarbomonocycle)substituted] trisubstituted 
benzoate, polymer with alkenylcarbomonocycle and alkylcarbomonocycle 
alkyl alkenoate (PMN P-25-66; Accession No. 303323) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section. The requirements of this section do 
not apply to quantities of the substance after they have been 
completely reacted or adhered (during photolithographic processes) onto 
a semiconductor wafer surface or similar manufactured article used in 
the production of semiconductor technologies.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining 
which persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), 
(g)(3)(i) and (ii), and (g)(5). For purposes of Sec.  721.72(e), the 
concentration is set at 1.0% by weight or volume. For purposes of Sec.  
721.72(g)(1), this substance may cause: acute toxicity, skin 
irritation, serious eye damage, skin sensitization, genetic toxicity, 
and specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (k), and (t). It is a significant new 
use to import the substance other than in solution unless in sealed 
containers weighing 5 kilograms or less. It is a significant new use to 
process the substance in any way that generates vapor, dust, mist, or 
aerosol in a non-enclosed process. It is a significant new use to 
manufacture the substance longer than 9 months.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12257   Sulfonium, bis(dihalo carbomonocycle)(halo 
carbomonocycle)-, salt with dihalo-sulfoalkyl 
[(alkenylcarbomonocycle)substituted] trisubstituted benzoate, polymer 
with alkenylcarbomonocycle and alkylcarbomonocycle alkyl alkenoate 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
sulfonium, bis(dihalo carbomonocycle)(halocarbomonocycle)-, salt with 
dihalo-sulfoalkyl [(alkenylcarbomonocycle)substituted] trisubstituted 
benzoate, polymer with alkenylcarbomonocycle and alkylcarbomonocycle 
alkyl alkenoate (PMN P-25-70) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section. The requirements of this section do not apply to 
quantities of the substance after they have been completely reacted or 
adhered (during photolithographic processes) onto a semiconductor wafer 
surface or similar manufactured article used in the production of 
semiconductor technologies.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining 
which persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), 
(g)(3)(i) and (ii), and (g)(5). For purposes of Sec.  721.72(e), the 
concentration is set at 1.0% by weight or volume. For purposes of Sec.  
721.72(g)(1), this substance may cause: acute toxicity, skin 
irritation, serious eye damage, skin sensitization, genetic toxicity, 
and specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (k), and (t). It is a significant new 
use to import the substance other than in solution unless in sealed 
containers weighing 5 kilograms or less. It is a significant new use to 
process the substance in any way that generates vapor, dust, mist, or 
aerosol in a non-enclosed process. It is a significant new use to 
manufacture the substance longer than 9 months.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12258   Sulfonium, bis(dihalo 
carbomonocycle)(halocarbomonocycle)-, salt with trihalobenzoate 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
sulfonium, bis(dihalo carbomonocycle)(halocarbomonocycle)-, salt with 
trihalobenzoate (PMN P-25-71) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section. The requirements of this section do not apply to 
quantities of the substance after they have been completely reacted or 
adhered (during photolithographic processes) onto a semiconductor wafer 
surface or similar manufactured article used in the production of 
semiconductor technologies.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining 
which persons are reasonably likely to be

[[Page 69720]]

exposed as required for Sec.  721.63(a)(1), engineering control 
measures (e.g., enclosure or confinement of the operation, general and 
local ventilation) or administrative control measures (e.g., workplace 
policies and procedures) shall be considered and implemented to prevent 
exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), 
(g)(3)(i) and (ii), and (g)(5). For purposes of Sec.  721.72(e), the 
concentration is set at 1.0% by weight or volume. For purposes of Sec.  
721.72(g)(1), this substance may cause: acute toxicity, skin 
irritation, serious eye damage, skin sensitization, genetic toxicity, 
and specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (k), and (t). It is a significant new 
use to import the substance other than in solution unless in sealed 
containers weighing 5 kilograms or less. It is a significant new use to 
process the substance in any way that generates vapor, dust, mist, or 
aerosol in a non-enclosed process. It is a significant new use to 
manufacture the substance longer than 9 months.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.12259  Aromatic sulfonium tricyclo salt with 
carbopolycycloalkyl ester polysubstitutedarylhetero-acid (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
aromatic sulfonium tricyclo salt with carbopolycycloalkyl ester 
polysubstitutedarylhetero-acid (PMN P-25-97; Accession No. 303607) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been completely reacted or adhered (during photolithographic processes) 
onto a semiconductor wafer surface or similar manufactured article used 
in the production of semiconductor technologies.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining 
which persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), 
(g)(3)(i) and (ii), and (g)(5). For purposes of Sec.  721.72(e), the 
concentration is set at 1.0% by weight or volume. For purposes of Sec.  
721.72(g)(1), this substance may cause: acute toxicity, skin 
irritation, serious eye damage, skin sensitization, genetic toxicity, 
and specific target organ toxicity. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (k), and (t). It is a significant new 
use to import the substance other than in solution unless in sealed 
containers weighing 5 kilograms or less. It is a significant new use to 
process the substance in any way that generates vapor, dust, mist, or 
aerosol in a non-enclosed process. It is a significant new use to 
manufacture the substance longer than 18 months.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

[FR Doc. 2026-22576 Filed 11-4-26; 8:45 am]
BILLING CODE 6560-50-P


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