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Notice2026-18948

Order Under Sections 362 and 365 of the Public Health Service Act Continuing the Suspension of the Right To Introduce Certain Persons From Countries Where a Quarantinable Communicable Disease Exists

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Published
September 16, 2026
Effective
September 11, 2026

Issuing agencies

Health and Human Services DepartmentCenters for Disease Control and Prevention

Abstract

The Centers for Disease Control and Prevention (CDC), a component of the Department of Health and Human Services (HHS), announces it is issuing an Order under Sections 362 and 365 of the Public Health Service Act, and associated implementing regulations, continuing the suspension of the right to introduce certain persons from countries where an outbreak of a quarantinable communicable disease exists. This Order was issued on September 11 and shall remain in effect through 4:59 p.m. Eastern Daylight Time (EDT) on Sunday, October 11, 2026. This Order may be amended or rescinded prior to that time at the discretion of the Director.

Full Text

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<title>Federal Register, Volume 91 Issue 178 (Wednesday, September 16, 2026)</title>
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[Federal Register Volume 91, Number 178 (Wednesday, September 16, 2026)]
[Notices]
[Pages 58673-58679]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2026-18948]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[Docket No. CDC-2026-0892]


Order Under Sections 362 and 365 of the Public Health Service Act 
Continuing the Suspension of the Right To Introduce Certain Persons 
From Countries Where a Quarantinable Communicable Disease Exists

AGENCY: Centers for Disease Control and Prevention (CDC), Department of 
Health and Human Services (HHS).

ACTION: Notice with comment period.

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SUMMARY: The Centers for Disease Control and Prevention (CDC), a 
component of the Department of Health and Human Services (HHS), 
announces it is issuing an Order under Sections 362 and 365 of the 
Public Health Service Act, and associated implementing regulations, 
continuing the suspension of the right to introduce certain persons 
from countries where an outbreak of a quarantinable communicable 
disease exists. This Order was issued on September 11 and shall remain 
in effect through 4:59 p.m. Eastern Daylight Time (EDT) on Sunday, 
October 11, 2026. This Order may be amended or rescinded prior to that 
time at the discretion of the Director.

DATES: This action took effect September 11, 2026, at 5:00 p.m. EDT.
    Written comments must be received on or before October 1, 2026.

ADDRESSES: You may submit comments, identified by Docket No. CDC-2026-
0892 by either of the methods listed below. Do not submit comments by 
email. CDC does not accept comments by email.
    <bullet> Federal eRulemaking Portal: <a href="http://www.regulations.gov">http://www.regulations.gov</a>. 
Follow the instructions for submitting comments.
    <bullet> Mail: Division of Global Migration Health, Centers for 
Disease Control and Prevention, 1600 Clifton Road NE, MS H16-4, 
Atlanta, GA 30329.
    Instructions: All submissions received must include the agency name 
and Docket Number. All relevant comments received will be posted 
without change to <a href="http://regulations.gov">http://regulations.gov</a>, including any personal 
information provided. For access to the docket to read background 
documents or comments received, go to <a href="http://www.regulations.gov">http://www.regulations.gov</a>.

FOR FURTHER INFORMATION CONTACT: Jordan Faircloth, Deputy Chief of 
Staff, Centers for Disease Control and Prevention, 1600 Clifton Road 
NE, MS V18-2, Atlanta, GA 30329. Phone: 404-639-7000. Email: 
<a href="/cdn-cgi/l/email-protection#56353235243331233a37223f3938251635323578313920"><span class="__cf_email__" data-cfemail="7b181f18091e1c0e171a0f121415083b181f18551c140d">[email&#160;protected]</span></a>.

SUPPLEMENTARY INFORMATION: On May 18, 2026, the Acting Director of the 
Centers for Disease Control and Prevention signed an Order prohibiting 
the introduction of certain persons who have departed from, or were 
otherwise present within, specified countries during the last 21 days. 
On May 22, 2026, the Assistant Secretary for Health (ASH), HHS, signed 
an Amended Order that reflected updates to 42 CFR 71.40 (f), which no 
longer provides an exemption for lawful permanent residents (LPRs) from 
such orders. CDC accepted comments on both the original Order and 
Amended Order through June 22, 2026. On June 21, 2026, the ASH signed a 
new 30-day Order continuing the previous Order, without change, and 
provided a 15-day comment period. On July 13, 2026, the ASH signed a 
new order continuing the previous Order without change and that 
responded to public comments as well as provided updates on the 
epidemiologic situation and status of the outbreak. On August 12, 2026, 
the ASH signed a new 30-day Order continuing the previous Order, 
without change, and provided a 15-day comment period. During the 
comment period for the August 12, 2026, Order, CDC received three 
comments, which are addressed below. With this notice, CDC is 
announcing the issuance of an Order that continues the suspension of 
the right to introduce certain persons who have departed from, or were 
otherwise present within, specified countries during the last 21 days. 
This Order is effective for a period of 30 days.

Response to Comments on Previous Orders

    Comment: All three commenters acknowledge that CDC has both the 
statutory authority and responsibility to protect public health and to 
take reasonable measures when there is a credible risk of introducing a 
serious communicable disease into the United States; the commenters 
also acknowledge the seriousness of the Ebola disease outbreak. Even 
considering the gravity of the situation, the commenters expressed 
concerns regarding the broad application of the Order, asserting that 
less restrictive measures would provide adequate public health 
protections.
    Commenters suggested that CDC consider using narrower, risk-based 
criteria rather than applying blanket restrictions to all covered 
individuals. They suggested considering a variety of factors, including 
specific locations visited, length of stay, activities, interactions, 
precautions followed, and reasons for travel. They suggested that CDC 
distinguish actual exposure risk rather than broad nationality- or 
route-based assumptions. One commenter recommended screening, 
diagnostic testing, health monitoring, and, where appropriate, domestic 
isolation as alternatives to application of the Order. Commenters 
asserted that such targeted approaches can protect the public while 
minimizing unnecessary disruptions to lawful travel, family 
reunification, humanitarian activities, and other legitimate interests.
    Response: CDC recognizes that individual risk may differ among 
persons who have been present in a designated country or place where 
the quarantinable communicable disease outbreak is occurring. However, 
CDC also considers the public health and other resources required to 
implement an Order issued under Sections 362 and 365 of the Public 
Health Service Act and the implementing regulation at 42 CFR 71.40. 
Based on such considerations, CDC has determined that a generally 
applicable threshold based on whether an individual was present in a 
designated country or place during the relevant period is both more 
protective of public health and more feasible to implement.
    The Order does contain exception mechanisms that permit 
consideration of individual circumstances where appropriate. For 
example, a customs officer may, with supervisory approval, except an 
individual based on the totality of the circumstances, including

[[Page 58674]]

significant humanitarian and public health interests. In addition, a 
person may be provisionally granted an exception by CDC, the basis of 
which is subsequently confirmed following a public health assessment at 
the time of entry and supported through the implementation of 
appropriate public health mitigation protocols.
    CDC does not agree that individualized exposure assessments, 
testing, symptom screening, or monitoring can presently be feasibly 
implemented and serve as a substitute for the Order for all covered 
persons. CDC is therefore making no changes in response to this 
comment.
    Comment: One commenter expressed concern that use of the term 
``presence'' within a covered country to include airside international 
transit passengers who did not clear host-nation customs, never entered 
local domestic infrastructure, and had zero exposure to local 
transmission clusters, violates the Administrative Procedure Act (APA), 
5 U.S.C. 706(2)(A). The commenter noted that Ebola is not an airborne 
pathogen, nor is it contagious during its incubation period, and that 
symptomatic airside transit passengers cannot transmit the virus, 
rendering a blanket exclusion of airside transit counter to established 
scientific facts. The commenter asserted that there is no 
epidemiological data demonstrating that airside international airport 
transit carries a community transmission risk profile justifying a 
blanket 21-day entry prohibition.
    Response: CDC agrees that Ebola disease is not transmitted through 
ordinary airborne exposure and that persons infected with Ebola virus 
generally do not transmit the virus before developing symptoms. The 
relevant public health concern under section 265, however, is not 
limited to whether an asymptomatic person can transmit Ebola virus 
while physically present in an airport. An infected person may travel 
internationally during the incubation period before developing symptoms 
and subsequently become symptomatic while in transit or after reaching 
another destination.
    As discussed in the previous response, CDC recognizes that 
individual exposure circumstances may differ among persons who have 
been present in a designated country or place where the quarantinable 
communicable disease outbreak is occurring. Whether a traveler cleared 
immigration or customs does not necessarily resolve all public health 
considerations relevant to that person's physical presence in the 
designated country or place or potential exposure. Airport transit may 
occur under varying circumstances, including differences in duration, 
movement within airport facilities, interactions with other persons and 
travelers, itinerary changes, or unanticipated delays. Moreover, 
implementation of the proposed limitations based on individual exposure 
circumstances would be more difficult to operationalize considering the 
volume of travelers at issue, as well as restraints on resources and 
personnel in the highly fluid context of international air travel.
    CDC therefore declines at this time to adopt the commenter's 
recommendation to categorically exclude all persons whose presence in a 
designated country or place consisted solely of airside airport 
transit.
    Comment: One commenter stated concern about Fifth Amendment Due 
Process protection of LPRs. Unlike non-resident aliens, returning LPRs 
possess robust Fifth Amendment Due Process protections (Landon v. 
Plasencia, 459 U.S. 21 (1982)). Sweeping LPRs into a total 21-day entry 
exclusion under 42 U.S.C. 265--while processing U.S. Citizens present 
in the exact same outbreak zones under 42 U.S.C. 264 domestic isolation 
protocols--violates Fifth Amendment Procedural Due Process and Equal 
Protection principles (Bolling v. Sharpe, 347 U.S. 497 (1954)).
    Response: This comment is outside the scope of the continued Order. 
The Order is consistent with CDC's foreign quarantine regulations, 
including 42 CFR 71.40, which exclude U.S. citizens and U.S. nationals 
from the suspension authority. Changes to Sec.  71.40 (f) to remove 
LPRs from the types of individuals to whom orders issued under such 
authority do not apply were properly promulgated pursuant to notice and 
comment rulemaking (91 FR 31362 (May 27, 2026)). Additionally, CDC 
notes that this approach helps conserve public health resources by 
attempting to limit the overall number of individuals arriving into the 
United States. CDC is therefore making no changes in response to this 
comment.
    Comment: All commenters urged CDC to continue monitoring the 
situation, and to make public health decisions based on the most recent 
epidemiological data and current circumstances. Commenters urged CDC to 
be mindful of its authorities and the importance of maintaining public 
trust.
    Response: CDC appreciates the comment and agrees that public health 
measures should be based on current epidemiological evidence and 
periodically reassessed as relevant conditions change. CDC will 
continue to evaluate the epidemiological conditions underlying the 
Order, the risk of international introduction, the effectiveness and 
availability of public health mitigation measures, and relevant 
information concerning implementation of the Order. If changing 
circumstances warrant modification of the geographic scope, covered 
populations, exceptions, or other provisions of the Order, CDC will 
consider such modifications consistent with 42 U.S.C. 265 and 42 CFR 
71.40.
    The Order also is temporary and subject to continuing reassessment. 
The current Order is effective for 30 days and is intended to 
facilitate an ongoing public health assessment and risk profile of the 
outbreak. CDC continues to evaluate epidemiological conditions, the 
risk of importation, the effectiveness and availability of mitigation 
measures, and other relevant public health information in determining 
whether the statutory and regulatory criteria remain satisfied. If 
those circumstances materially change, CDC will consider whether the 
Order should be modified, narrowed, or discontinued.
    CDC agrees that transparency regarding both the public health 
rationale for the Order and the limits of CDC's authority is important 
to maintaining public trust. CDC will continue to provide information 
concerning the epidemiological basis for its actions and to reassess 
whether continued exercise of the authority under 42 U.S.C. 265 remains 
necessary in light of evolving public health conditions.
    CDC carefully considered all comments and determined that they did 
not warrant changes to the requirements of the Order issued August 12, 
2026. The new Order, issued on September 11, 2026, provides updated 
information regarding the status of the Ebola disease outbreak and CDC 
response efforts and maintains the previous travel restrictions.
    CDC will accept comments for this Order using docket CDC-2026-0892. 
A copy of the Order is provided below and a copy of the signed Order 
can be found at <a href="https://www.cdc.gov/port-health/legal-authorities/evdorder.html">https://www.cdc.gov/port-health/legal-authorities/evdorder.html</a>.

[[Page 58675]]

U.S. Department of Health and Human Services Centers for Disease 
Control and Prevention (CDC)

Order Under Sections 362 & 365 of the Public Health Service Act (42 
U.S.C. 265, 268) and 42 CFR Sec.  71.40

Continuing the Suspension of the Right To Introduce Certain Persons 
From Countries Where a Quarantinable Communicable Disease Exists

I. Executive Summary

    The Centers for Disease Control and Prevention (CDC), a component 
of the U.S. Department of Health and Human Services (HHS), issues this 
Order pursuant to Sections 362 and 365 of the Public Health Service 
(PHS) Act, 42 U.S.C. 265 and 268, and their implementing regulations. 
This Order continues the suspension of the right to introduce ``covered 
aliens,'' as defined herein, into the United States for a period of 
thirty days, subject to the outcome of an ongoing comprehensive public 
health risk assessment. This Order is necessary to protect public 
health in the United States from the serious risk posed by the 
introduction of Ebola disease into the United States by covered aliens 
based on the outbreak of Ebola disease caused by the Bundibugyo virus 
confirmed present in the Democratic Republic of the Congo (DRC) and, 
until recently, in Uganda.
    This Order applies to covered aliens who have departed from, or 
were otherwise present within, DRC, Uganda, or South Sudan during the 
last 21 days (regardless of their country of origin). This Order is 
based on an assessment of the most recently available data and current 
conditions regarding the Ebola disease outbreak.
    This Order is time-limited and shall be in effect for 30 days from 
the date of issuance. This Order is intended to address the serious 
risk of introduction of Ebola disease into the United States, while 
allowing the U.S. Government to continue an ongoing assessment of the 
current and evolving conditions of the Ebola disease outbreak in 
consultation with other stakeholders.
    This Order is severable from previously issued Orders under 
Sections 362 and 365 of the Public Health Service (PHS) Act, 42 U.S.C. 
265 and 268, and their implementing regulations under 42 CFR part 71. 
Any provision of this Order held to be invalid or unenforceable by its 
terms, or as applied to any person or circumstance, shall be construed 
so as to continue to give the maximum effect to the provision permitted 
by law, unless such holding shall be one of utter invalidity or 
unenforceability.

II. Authority, Scope, and Purpose

    I issue this Order pursuant to Sections 362 and 365 of the Public 
Health Service (PHS) Act, 42 U.S.C. 265 and 268, and their implementing 
regulations under 42 CFR part 71,\1\ which authorize the CDC Director 
to suspend the right to introduce \2\ persons into the United States 
when the Director determines that the existence of a quarantinable 
communicable disease in a foreign country or place creates a serious 
danger of the introduction of such disease into the United States and 
the danger is so increased by the introduction of persons from the 
foreign country or place that a temporary suspension of the right of 
such introduction is necessary to protect public health.
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    \1\ Control of Communicable Diseases; Foreign Quarantine: 
Suspension of the Right to Introduce and Prohibition of Introduction 
of Persons into United States from Designated Foreign Countries or 
Places for Public Health Purposes, 85 FR 56424 (Sept. 11, 2020), as 
amended by 91 FR 31362 (May 27, 2026); 42 CFR 71.40.
    \2\ Suspension of the right to introduce means to cause the 
temporary cessation of the effect of any law, rule, decree, or order 
pursuant to which a person might otherwise have the right to be 
introduced or seek introduction into the United States. 42 CFR 
71.40(b)(5).
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    This Order applies to persons who have departed from, or were 
otherwise present within, DRC, Uganda, and South Sudan during the last 
21 days (regardless of their country of origin), including lawful 
permanent residents of the United States, subject to the exceptions 
detailed below. For purposes of this Order, I refer to persons covered 
by the Order as ``covered aliens.''
    This Order does not apply to the following:
    <bullet> U.S. citizens and U.S. nationals; \3\
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    \3\ 42 CFR 71.40(f).
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    <bullet> Members of the armed forces of the United States and 
associated personnel, U.S. government personnel serving overseas, 
associated personnel, and their spouses and children, subject to 
required assurances; \4\
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    \4\ 42 CFR 71.40(e)(1) and (2).
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    <bullet> Persons whom customs officers determine, with approval 
from a supervisor, should be excepted from this Order based on the 
totality of the circumstances, including consideration of significant 
law enforcement, officer and public safety, humanitarian, and public 
health interests. The U.S. Department of Homeland Security (DHS) will 
consult with CDC regarding the standards for such exceptions to help 
ensure consistency with current CDC guidance and public health 
recommendations; and
    <bullet> Persons who would otherwise be subject to this Order, who 
are permitted to enter the United States based on an exception 
provisionally granted by CDC with confirmation based on a public health 
assessment at time of entry under a DHS-approved process documented and 
shared with CDC which includes appropriate public health mitigation 
protocols, per CDC guidance.
    The purpose of this Order is twofold. First, this Order aims to 
continue minimizing the number of covered aliens entering the United 
States who have been within countries experiencing or that have 
recently experienced a known or suspected outbreak of Ebola disease and 
thereby reduce the risk of introduction of Ebola disease into the 
United States. Second, this Order is intended to facilitate an ongoing 
public health assessment and risk profile of the Ebola disease 
outbreak. Thirty days is the amount of time necessary for CDC to 
continue monitoring the situation and determine if there has been a 
material change to the risk of importation and whether this Order would 
remain in effect or requires modification. Such information will enable 
the CDC Director to make an informed determination regarding what 
restrictions are necessary going forward and provide the opportunity 
for the development of a comprehensive mitigation and containment plan 
in consultation with stakeholders.

III. Factual Basis

A. Ebola Disease

    Viral hemorrhagic fever refers to a group of severe illnesses 
caused by certain viruses that damage the body's blood vessels and 
affect the ability of the blood to clot properly. Viral hemorrhagic 
fevers include diseases such as Ebola, Marburg, Lassa fever, and dengue 
hemorrhagic fever.
    Bundibugyo virus disease (BVD) is a severe and often fatal illness 
caused by one of the viruses in the Ebola family. Ebola disease 
outbreaks occur mainly in parts of sub-Saharan Africa and can spread 
rapidly in communities with limited healthcare resources. Ebola disease 
caused by the Bundibugyo virus is a rare form of Ebola first identified 
during an outbreak in Bundibugyo District, Uganda, in 2007. Bundibugyo 
virus is one of several species within the orthoebolavirus family and 
causes symptoms similar to other forms of Ebola, including fever, 
weakness, vomiting, diarrhea, and, in severe cases, hemorrhagic 
complications and organ failure. The disease spreads through direct 
contact with infected bodily fluids or contaminated materials.
    The incubation period for Ebola disease caused by the Bundibugyo 
virus is typically between 2 and 21 days, with

[[Page 58676]]

most people developing symptoms within 4 to 10 days after exposure. 
During this incubation period, infected persons do not spread the virus 
until symptoms begin.
    Screening for Bundibugyo virus disease focuses on identifying 
symptoms and possible exposure history, such as recent travel to 
affected areas or contact with infected aliens. Suspected patients are 
evaluated for symptoms including fever, weakness, vomiting, diarrhea, 
and bleeding, and laboratory confirmation is performed using 
specialized tests such as PCR (polymerase chain reaction) to detect the 
virus in blood and other body fluid samples. Health authorities also 
use temperature checks, contact tracing, and isolation procedures to 
prevent transmission.
    There are currently no widely approved vaccines or specific 
antiviral treatments for the Bundibugyo strain of Ebola disease. 
Treatment mainly consists of supportive care, including intravenous 
fluids, electrolyte replacement, oxygen support, pain and fever 
management, and treatment of secondary infections. Early medical care 
significantly improves survival chances. Robust public health measures 
such as early detection, rapid isolation, strong infection prevention 
measures (i.e., use of personal protective equipment [PPE]), and 
monitoring of contacts are critical to controlling outbreaks and 
reducing deaths. A clinical trial of monoclonal antibodies is presently 
underway in DRC.\5\ However, experts expect it will be several months 
before these therapeutics are potentially available for wider use.
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    \5\ WHO, Patient enrolment begins in a scientific trial to 
identify the first effective treatments for Bundibugyo virus 
disease, <a href="https://www.who.int/news/item/02-07-2026-patient-enrolment-begins-in-a-scientific-trial-to-identify-the-first-effective-treatments-for-bundibugyo-virus-disease">https://www.who.int/news/item/02-07-2026-patient-enrolment-begins-in-a-scientific-trial-to-identify-the-first-effective-treatments-for-bundibugyo-virus-disease</a> (last accessed September 10, 
2026).
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B. Ongoing Bundibugyo Virus Disease Outbreak

    The ongoing outbreak of Ebola virus disease caused by the 
Bundibugyo virus in DRC continues to escalate in intensity and expand 
geographically. The outbreak is now the largest and deadliest Ebola 
outbreak in DRC's history, as well as the second largest Ebola outbreak 
on record.\6\ The outbreak remains centered in eastern DRC's Ituri 
Province, although cases have been identified in North Kivu, South 
Kivu, Haut-Uele, Tshopo, and Bas-U[eacute]l[eacute] provinces. This 
geographic expansion is concerning, particularly given that response 
efforts are still not at the scale required for outbreak containment. 
On August 9, prior to the issuance of the last Order, DRC reported 
4,318 confirmed cases and 2,011 deaths across 41 health zones. Cases 
and deaths have continued to increase and as of September 9, DRC 
reports 6,779 confirmed cases and 3,267 deaths across 61 health zones.
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    \6\ Kabasele D, Meyer E, Kabore I, et al. Notes from the Field: 
Characteristics and Monitoring of the 2026 Outbreak of Ebola Disease 
Caused by Bundibugyo Virus--Democratic Republic of the Congo, August 
2026. MMWR Morb Mortal Wkly Rep 2026;75:554-556. DOI: <a href="http://dx.doi.org/10.15585/mmwr.mm7535e1">http://dx.doi.org/10.15585/mmwr.mm7535e1</a>.
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    As recently as September 10, 2026, the ongoing Bundibugyo Ebola 
virus outbreak in DRC continues to spread despite response efforts. 
Although contact tracing for confirmed cases has risen to approximately 
87% nationwide, these efforts are still well below the operational 
threshold of 95% needed to successfully slow the spread of this 
outbreak.\7\ Recent assessments indicate that the true magnitude of the 
outbreak may be two to four times greater than reported surveillance 
data suggest. Surveillance challenges persist in the most heavily 
affected areas, with conflict and insecurity, weak health 
infrastructure, and relatively porous borders in the region 
complicating containment efforts. These conditions increase the 
likelihood that cases will remain undetected and that infected persons 
may travel outside affected areas before being identified by public 
health authorities.
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    \7\ Ministry of Public Health, Hygiene and Social Welfare, 
Situation Report on the 17th Ebola Virus Outbreak Disease/DRC--
August 6, 2026, <a href="https://insp.cd/category/activite-cousp/">https://insp.cd/category/activite-cousp/</a> (last 
accessed September 10, 2026).
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    As of August 27, 2026, the 42-day enhanced monitoring period--
defined as twice the maximum incubation period for Ebola (21 days) per 
international guidance has been completed in Uganda.\8\ Over the course 
of the outbreak in Uganda, the country reported 20 confirmed cases of 
Ebola disease and two confirmed deaths, as well as one probable case 
and one probable death. The last confirmed case was reported on June 
21, 2026. Of the confirmed cases, 15 were imported cases and 5 were 
secondary cases linked to imported cases from DRC.\9\ All cases in 
Uganda have been epidemiologically linked to the ongoing outbreak in 
DRC, with cross-border importations having occurred, resulting in 
secondary transmission among family members and caregivers.\10\ Ugandan 
authorities activated emergency response systems, expanded 
surveillance, and strengthened screening at borders and health 
facilities. Although the country has achieved successful containment of 
the outbreak, continued overland travel from DRC poses an ongoing risk 
of cross-border transmission, particularly among healthcare workers and 
in western Ugandan districts that serve as points of entry for 
travelers seeking medical care.
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    \8\ World Health Organization, Uganda ends Ebola outbreak 
following completion of 42-day countdown, <a href="https://www.afro.who.int/countries/uganda/news/uganda-ends-ebola-outbreak-following-completion-42-day-countdown">https://www.afro.who.int/countries/uganda/news/uganda-ends-ebola-outbreak-following-completion-42-day-countdown</a> (last accessed September 10, 2026).
    \9\ WHO, Disease Outbreak News: Ebola disease caused by 
Bundibugyo virus, Democratic Republic of the Congo & Uganda, <a href="https://www.who.int/emergencies/disease-outbreak-news/item/2026-DON613">https://www.who.int/emergencies/disease-outbreak-news/item/2026-DON613</a> 
(last accessed September 10, 2026).
    \10\ CDC internal data.
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    To date, South Sudan has not reported any confirmed Ebola disease 
cases in the current outbreak.\11\ However, it is considered at high 
risk because of its close border with affected areas in eastern DRC, 
limited healthcare infrastructure, and cross-border population 
movement. Regional and international agencies, including WHO and Africa 
CDC, are supporting preparedness measures, surveillance, and 
coordination among the three countries to prevent wider spread. Despite 
these efforts, there continues to be a risk that the outbreak in DRC 
could spread to South Sudan through cross-border travel by infected 
individuals during the virus's incubation period, when they have been 
exposed but are not yet showing symptoms.
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    \11\ CDC, Ebola Outbreak: Current Situation, <a href="https://www.cdc.gov/ebola/situation-summary/index.html">https://www.cdc.gov/ebola/situation-summary/index.html</a> (last visited 
September 10, 2026).
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    Travelers moving between affected countries and major international 
transit hubs could unknowingly carry the Bundibugyo virus before 
becoming ill. Such travelers may spread the outbreak beyond the 
affected countries and ultimately reach the United States. DRC, Uganda, 
and South Sudan are connected to the global aviation network through a 
series of regional and international transit hubs that provide pathways 
into the United States. Travelers departing from outbreak-affected 
regions frequently transit through densely populated metropolitan 
airports such as Addis Ababa Bole International Airport (ADD), Jomo 
Kenyatta International Airport (NBO) in Nairobi, Brussels Airport 
(BRU), Hamad International Airport (DOH) in Doha, Dubai International 
Airport (DXB), and Istanbul Airport (IST), all of which maintain 
extensive passenger connectivity to major U.S. gateway airports 
including John F. Kennedy International Airport (JFK), Washington 
Dulles International Airport (IAD), Hartsfield-Jackson Atlanta 
International

[[Page 58677]]

Airport (ATL), Chicago O'Hare International Airport (ORD), and Los 
Angeles International Airport (LAX). These international transportation 
corridors support continuous movement of travelers between Central and 
East Africa and major U.S. metropolitan centers, increasing the 
likelihood that aliens exposed to Ebola disease could enter the United 
States before symptoms become apparent. Complex multi-leg itineraries 
and the rapid pace of international travel create substantial 
challenges for identifying potentially infected travelers before 
arrival.
    A traveler infected in outbreak regions of DRC may transit through 
multiple countries and major international airports before developing 
fever or other clinical signs of disease. The risk of Bundibugyo virus 
disease introduction into the United States is heightened by the 
virus's incubation period, which can extend up to 21 days, allowing 
infected persons to travel internationally while asymptomatic and 
therefore unlikely to be detected through routine symptom-based 
screening measures. The current outbreak has already demonstrated this 
risk: a physician infected while providing patient care in DRC traveled 
internationally before becoming ill and was diagnosed only after 
arriving in France.\12\ That case required extensive public health 
coordination, including federal, state, and local government efforts to 
identify, notify, and monitor potentially exposed U.S. citizens, 
demonstrating that a single infected traveler can impose significant 
cross-border public health response demands even without onward 
transmission occurring within the United States. Accordingly, the 
interconnected nature of global air travel presents a credible pathway 
for Bundibugyo virus disease importation into the United States, 
underscoring the importance of aggressive surveillance, traveler 
monitoring, airport public health screening, healthcare preparedness, 
and rapid containment capabilities.
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    \12\ World Health Organization, WHO Director-General's opening 
remarks at the media briefing--24 June 2026, available at https://
www.who.int/news-room/speeches/item/who-director-general-s-opening-
remarks-at-the-media-briefing--24-june-2026 (last accessed September 
10, 2026).
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    Travelers utilizing air transit pathways originating in or passing 
through DRC, Uganda, and South Sudan include non-U.S. citizens, 
including regional migrants, foreign contract workers, humanitarian 
personnel, business travelers, students, refugees, and third-country 
nationals moving through international aviation hubs in Africa, the 
Middle East, and Europe. Many travelers entering U.S.-bound itineraries 
from these pathways may do so under temporary visas, refugee or asylum 
processing mechanisms, international organizational travel, or multi-
country itineraries that obscure their original point of departure. As 
a result, public health screening and border security systems face 
heightened operational complexity in identifying travelers with recent 
exposure histories linked to Ebola-affected regions, particularly when 
travelers originate from or transit through multiple jurisdictions 
prior to arrival at major U.S. metropolitan airports.
    CDC has issued a series of Travel Health Notices (THNs) for the 
region; the THNs for the affected provinces have escalated over time. 
On August 4, 2026, CDC escalated the THN issued for Ituri and North 
Kivu Provinces of DRC to a Level 4 (avoid all travel).\13\ A Level 3 
THN (reconsider nonessential travel) is currently in place for South 
Kivu, Haut-U[eacute]l[eacute], and Tshopo Provinces of DRC.\14\ The 
rest of DRC and all of Uganda remain under a Level 2 THN (practice 
enhanced precautions).\15\ Modifications to the THNs reflect the 
geographic distribution of reported cases and do not indicate a reduced 
level of concern regarding the outbreak, which continues to expand in 
affected areas and poses a risk of further transmission and geographic 
spread.
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    \13\ CDC issued a Level 2 THN (practice enhanced precautions) 
for Ituri and North Kivu Provinces of DRC on May 15, 2026; this was 
escalated to a Level 3 THN (reconsider nonessential travel) on May 
18, 2026. The current Level 4 THN is available at <a href="https://wwwnc.cdc.gov/travel/notices/level4/ebola-drc-provinces">https://wwwnc.cdc.gov/travel/notices/level4/ebola-drc-provinces</a> (last 
accessed September 10, 2026).
    \14\ South Kivu was added to the Level 3 THN on May 22, 2026; 
Haut-U[eacute]l[eacute] and Tshopo Provinces were added on August 4, 
2026. The current THN is available at <a href="https://wwwnc.cdc.gov/travel/notices/level3/ebola-democratic-republic-of-the-congo">https://wwwnc.cdc.gov/travel/notices/level3/ebola-democratic-republic-of-the-congo</a> (last accessed 
September 10, 20262026).
    \15\ CDC issued a Level 1 THN (practice usual precautions) for 
Uganda on May 15, 2026. On May 27, 2026, the THN for Uganda was 
elevated to a Level 2. On June 15, 2026, CDC issued a Level 2 THN 
for the remainder of DRC and Uganda. The current THN is available at 
<a href="https://wwwnc.cdc.gov/travel/notices/level2/ebola-drc-uganda">https://wwwnc.cdc.gov/travel/notices/level2/ebola-drc-uganda</a> (last 
accessed September 10, 2026).
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    CDC modeling indicates that, absent rapid and sustained public 
health interventions, the outbreak could become one of the largest 
Ebola epidemics ever recorded.\16\ The analysis further demonstrates 
that early identification of cases, contact tracing, isolation and 
treatment of symptomatic persons, community engagement, and safe burial 
practices are critical to reducing transmission and mitigating outbreak 
growth.\17\ CDC has concluded that the current outbreak is already the 
largest known outbreak of Bundibugyo virus disease and that large-
scale, sustained public health measures are necessary to prevent 
further international spread of the disease and to reduce the risk of 
introduction of infected persons into the United States.\18\
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    \16\ Mooring EQ, Koval WT, Routledge I, et al. Modeled Scenario 
Projections for the Ebola Disease Outbreak Caused by Bundibugyo 
Virus, 2026. MMWR Morb Mortal Wkly Rep 2026;75:285-289. DOI: <a href="http://dx.doi.org/10.15585/mmwr.mm7522e1">http://dx.doi.org/10.15585/mmwr.mm7522e1</a>.
    \17\ Id.
    \18\ Id.
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    Restricting entry of covered aliens into the United States reduces 
the volume of higher-risk international arrivals requiring public 
health monitoring and follow-up. By limiting the number of potentially 
exposed travelers entering through major U.S. ports of entry, federal, 
state, and local public health authorities have concentrated finite 
surveillance, screening, contact tracing, quarantine management, and 
medical monitoring resources on returning U.S. citizens and U.S. 
nationals, including those who have worked in the outbreak areas.
    Paired with the DHS arrival restrictions redirecting travelers to 
specific U.S. airports,\19\ this approach has reduced operational 
strain on airport screening systems, CDC port health stations, public 
health laboratories, and healthcare facilities responsible for 
evaluating suspected Bundibugyo virus disease cases. It also has 
improved the ability of authorities to conduct detailed exposure 
assessments, ensure compliance with monitoring requirements during the 
21-day incubation period, rapidly identify symptomatic travelers, and 
allocate specialized isolation and treatment capacity more effectively. 
In the context of a rapidly evolving Bundibugyo virus disease outbreak 
with significant cross-border mobility, prioritizing surveillance 
efforts toward a smaller and more traceable traveler population has 
strengthened the overall effectiveness of U.S. disease containment and 
border health security operations.
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    \19\ DHS, Arrival Restrictions Applicable to Flights Carrying 
Persons Who Have Recently Traveled From or Were Otherwise Present 
Within the Democratic Republic of the Congo, Uganda, or South Sudan, 
91 FR 29896 (May 21, 2026).
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IV. Legal Basis for This Order Under Sections 362 and 365 of the Public 
Health Service Act and 42 CFR 71.40

    CDC is issuing this Order pursuant to sections 362 and 365 of the 
Public Health Service Act (42 U.S.C. 265, 268) and the implementing 
regulation at 42 CFR 71.40. In accordance with these authorities, the 
CDC Director is permitted to prohibit, in whole or in

[[Page 58678]]

part, the introduction into the United States of persons from 
designated foreign countries (or one or more political subdivisions or 
regions thereof) or places, only for such period of time that the 
Director deems necessary to avert the serious danger of the 
introduction of a quarantinable communicable disease,\20\ by issuing an 
Order in which the Director determines that:
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    \20\ See Exec. Order No. 13,295, Revised List of Quarantinable 
Communicable Diseases (April 2, 2003) (adding viral hemorrhagic 
fevers, including Ebola, to the U.S. federal list of quarantinable 
communicable diseases).
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    (1) By reason of the existence of any quarantinable communicable 
disease in a foreign country (or one or more political subdivisions or 
regions thereof) or place there is serious danger of the introduction 
of such quarantinable communicable disease into the United States; and
    (2) This danger is so increased by the introduction of persons from 
such country (or one or more political subdivisions or regions thereof) 
or place that a suspension of the right to introduce such persons into 
the United States is required in the interest of public health.\21\
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    \21\ 42 U.S.C. 265; 42 CFR 71.40.
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    Section 362 and the implementing regulation provide the Director 
with a public health tool to suspend introduction of persons not only 
to prevent the introduction of a quarantinable communicable disease, 
but also to aid in continued efforts to mitigate spread of that 
disease.\22\
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    \22\ 85 FR 56424 at 56425-26.
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    The term ``introduction into the United States'' is defined in 42 
CFR 71.40 as ``the movement of a person from a foreign country (or one 
or more political subdivisions or regions thereof) or place, or series 
of foreign countries or places, into the United States so as to bring 
the person into contact with persons or property in the United States, 
in a manner that the Director determines to present a risk of 
transmission of a quarantinable communicable disease to persons, or a 
risk of contamination of property with a quarantinable communicable 
disease.'' 42 CFR 71.40(b)(1). Similarly, the term ``serious danger of 
the introduction of such quarantinable communicable disease into the 
United States'' is defined as, ``the probable introduction of one or 
more persons capable of transmitting the quarantinable communicable 
disease into the United States, even if persons or property in the 
United States are already infected or contaminated with the 
quarantinable communicable disease.'' 42 CFR 71.40(b)(3).
    Section 71.40(b)(2) defines ``[p]rohibit, in whole or in part, the 
introduction into the United States of persons'' in Section 362 to mean 
``to prevent the introduction of persons into the United States by 
suspending any right to introduce into the United States, physically 
stopping or restricting movement into the United States.'' See also 42 
U.S.C. 265 (authorizing the prohibition when the danger posed by the 
communicable disease ``is so increased by the introduction of persons . 
. . from such country . . . that a suspension of the right to introduce 
such persons . . . is required in the interest of public health'').
    As stated in the Final Rule for 42 CFR 71.40, CDC ``may, in its 
discretion, consider a wide array of facts and circumstances when 
determining what is required in the interest of public health in a 
particular situation . . . includ[ing] . . . [t]he overall number of 
cases of disease; any large increase in the number of cases over a 
short period of time; the geographic distribution of cases; any 
sustained (generational) transmission; the method of disease 
transmission; morbidity and mortality associated with the disease; the 
effectiveness of contact tracing; the adequacy of state and local 
health care systems; and the effectiveness of state and local public 
health systems and control measures.'' \23\
---------------------------------------------------------------------------

    \23\ Id. at 56444.
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    As stated in 42 CFR 71.40, this Order does not apply to U.S. 
citizens, U.S. nationals, members of the armed forces of the United 
States and associated personnel if the Secretary of War provides 
assurance to the Director that the Secretary of War has taken or will 
take measures such as quarantine or isolation, or other measures 
maintaining control over such individuals, to prevent the risk of 
transmission of the quarantinable communicable disease into the United 
States, or United States government employees or contractors on orders 
abroad, or their accompanying family members who are on their orders or 
are members of their household, if the Director receives assurances 
from the relevant head of agency and determines that the head of the 
agency or department has taken or will take measures such as quarantine 
or isolation, to prevent the risk of transmission of a quarantinable 
communicable disease into the United States.\24\
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    \24\ 42 CFR 71.40(e) and (f).
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    In addition, this Order does not apply to additional classes of 
persons excepted by the CDC Director. Creating exceptions in the Order 
is consistent with Section 362 and 42 CFR 71.40. Section 362 explicitly 
states that the prohibition of introduction into the United States may 
be ``in whole or in part.'' This phrase is also included in section 
71.40(a) and, as explained in the Final Rule, is intended to allow the 
Director to narrowly tailor the use of the authority to what is 
required in the interest of public health.\25\ As noted in the Final 
Rule for 42 CFR 71.40, the CDC Director may also take into account 
international obligations and humanitarian concerns.\26\ Pursuant to 
this capability, CDC is therefore excepting certain categories of 
persons, as described herein.
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    \25\ 85 FR 56424 at 56444.
    \26\ Id. at 56447.
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    This Order will be in effect for 30 days to avert the serious 
danger of the introduction, transmission, and spread of Ebola disease 
into the United States. Finally, as directed by 42 CFR 71.40(c), this 
Order sets out the following:
    (1) The foreign countries (or one or more political subdivisions or 
regions thereof) or places from which the introduction of persons is 
being prohibited;
    (2) The period of time or circumstances under which the 
introduction of any persons or class of persons into the United States 
is being prohibited;
    (3) The conditions under which that prohibition on introduction 
will be effective, in whole or in part, including any relevant 
exceptions that the Director determines are appropriate;
    (4) The means by which the prohibition will be implemented; and
    (5) The serious danger posed by the introduction of the 
quarantinable communicable disease in the foreign country or countries 
(or one or more political subdivisions or regions thereof) or places 
from which the introduction of persons is being prohibited.

V. Determination and Implementation

    Based on the foregoing, I hereby determine that Ebola disease, a 
highly transmissible quarantinable communicable disease, is confirmed 
currently present in DRC and recently present in Uganda. There is a 
material risk that the outbreak will spread to South Sudan and again to 
Uganda. I also determine that the prevalence of Ebola disease in these 
foreign countries constitutes a serious danger of the introduction of 
this disease into the United States due to the limited screening and 
testing and mitigation measures currently available. Finally, I 
determine that a temporary 30-day suspension of the right to introduce

[[Page 58679]]

covered aliens is necessary to protect the public health from the 
serious danger of the introduction of Ebola disease into the United 
States, pending an ongoing public health assessment of the Ebola 
disease outbreak.
    I consulted with the Department of State, DHS, and other federal 
departments as needed before I issued this Order and requested that DHS 
aid in the enforcement of this Order because CDC does not have the 
capability, resources, or personnel needed to do so.\27\ As part of the 
consultation, DHS developed operational plans for implementing this 
Order. These plans are consistent with the language of this Order.
---------------------------------------------------------------------------

    \27\ 42 U.S.C. 268; 42 CFR 71.40(d).
---------------------------------------------------------------------------

    Although this Order is not a rule subject to notice and comment 
under the Administrative Procedure Act (APA) and is issued with 
immediate effect, in order to ensure that the forthcoming public health 
risk assessment is informed by public input, the Order is being issued 
with a simultaneous 15-day comment period.
    This Order takes effect at 5:00 p.m. Eastern Daylight Time on 
Friday, September 11, 2026. For individuals intending to travel to the 
United States by air, the Order will apply to flights departing after 
4:59 p.m. Eastern Daylight Time on Friday, September 11, 2026.
* * * * *
    In testimony whereof, the Assistant Secretary for Health, U.S. 
Department of Health and Human Services, has hereunto set his hand at 
______ this 11th day of September, 2026.

    Dated:

Admiral Brian Christine, MD,
Assistant Secretary for Health (ASH) and Head of the United States 
Public Health Service (USPHS) Commissioned Corps Department of Health 
and Human Services.

Public Participation

    Interested persons or organizations are invited to participate by 
submitting written views, recommendations, and data so that the public 
can provide input that may inform the forthcoming public health risk 
assessment and whether any subsequent exercise of this authority is 
necessary.
    Please note that comments received, including attachments and other 
supporting materials, are part of the public record and are subject to 
public disclosure. Comments will be posted on <a href="https://www.regulations.gov">https://www.regulations.gov</a>. Therefore, do not include any information in your 
comment or supporting materials that you consider confidential or 
inappropriate for public disclosure. If you include your name, contact 
information, or other information that identifies you in the body of 
your comments, that information will be on public display. CDC will 
review all submissions and may choose to redact, or withhold, 
submissions containing private or proprietary information such as 
Social Security numbers, medical information, inappropriate language, 
or duplicate/near duplicate examples of a mass-mail campaign. Do not 
submit comments by email. CDC does not accept comment by email.

Authority

    The authority for this order is Sections 362 and 365 of the Public 
Health Service Act (42 U.S.C. 265, 268), as amended.

Brian Christine,
Admiral, Assistant Secretary for Health (ASH) and Head of the United 
States Public Health Service (USPHS) Commissioned Corps Department of 
Health and Human Services.
[FR Doc. 2026-18948 Filed 9-15-26; 8:45 am]
BILLING CODE 4163-18-P


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Indexed from Federal Register on September 16, 2026.

This is legal information, not legal advice. Laws vary by jurisdiction and change frequently. Always verify current law with official sources and consult a licensed attorney in your jurisdiction for advice on your specific situation.