Notice2026-11591
Certain New Chemicals; Receipt and Status Information for November 2025, January 2026, and February 2026
Primary source
Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.
Published
June 10, 2026
Issuing agencies
Environmental Protection Agency
Abstract
This document announces the Agency's receipt of new chemical submissions under the Toxic Substances Control Act (TSCA), including information about the receipt of a Premanufacture Notice (PMN), Significant New Use Notice (SNUN), Microbial Commercial Activity Notice (MCAN), and an amendment to a previously submitted notice; test information; a biotechnology exemption application; an application for a test marketing exemption (TME); and a notice of commencement of manufacture (defined by statute to include import) (NOC) for a new chemical substance. This document also provides a periodic status report on the new chemical substances that are currently under EPA review or have recently concluded review. EPA is hereby providing notice of receipt of this information, as required by TSCA, and an opportunity to comment. This document covers new chemical submissions that have passed an initial screening and, for PMNs, SNUNs and MCANs, were determined to be complete during the period from 2/1/2026 to 2/28/ 2026 regardless of the initial submission date.
Full Text
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<title>Federal Register, Volume 91 Issue 111 (Wednesday, June 10, 2026)</title>
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[Federal Register Volume 91, Number 111 (Wednesday, June 10, 2026)]
[Notices]
[Pages 35204-35208]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2026-11591]
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ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-OPPT-2026-1387; FRL-13202-02-OCSPP]
Certain New Chemicals; Receipt and Status Information for
November 2025, January 2026, and February 2026
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of receipt and request for comment.
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SUMMARY: This document announces the Agency's receipt of new chemical
submissions under the Toxic Substances Control Act (TSCA), including
information about the receipt of a Premanufacture Notice (PMN),
Significant New Use Notice (SNUN), Microbial Commercial Activity Notice
(MCAN), and an amendment to a previously submitted notice; test
information; a biotechnology exemption application; an application for
a test marketing exemption (TME); and a notice of commencement of
manufacture (defined by statute to include import) (NOC) for a new
chemical substance. This document also provides a periodic status
report on the new chemical substances that are currently under EPA
review or have recently concluded review. EPA is hereby providing
notice of receipt of this information, as required by TSCA, and an
opportunity to comment. This document covers new chemical submissions
that have passed an initial screening and, for PMNs, SNUNs and MCANs,
were determined to be complete during the period from 2/1/2026 to 2/28/
2026 regardless of the initial submission date.
DATES: Comments must be received on or before July 10, 2026.
ADDRESSES: Submit your comments, identified by docket identification
(ID) number EPA-HQ-OPPT-2026-1387 and the specific case number provided
in this document for the chemical substance related to your comment,
online at <a href="https://www.regulations.gov">https://www.regulations.gov</a>. Follow the online instructions
for submitting comments. Do not submit electronically any information
you consider to be Confidential Business Information (CBI) or other
information whose disclosure is restricted by statute. Additional
instructions on commenting on and visiting the docket, along with more
information about dockets generally, are available at <a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>.
FOR FURTHER INFORMATION CONTACT: For technical information: Jim Rahai,
Office of Chemical Safety and Pollution Prevention (OCSPP-OMCO-RISD),
Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington,
DC 20460-0001; telephone number: (202) 564-8593; email address:
<a href="/cdn-cgi/l/email-protection#0e7c6f666f67206467634e6b7e6f20696178"><span class="__cf_email__" data-cfemail="ccbeada4ada5e2a6a5a18ca9bcade2aba3ba">[email protected]</span></a>.
For general information: The TSCA-Hotline, Goodwill of the Finger
Lakes, 422 South Clinton Ave., Rochester, NY 14620; telephone number:
(202) 554-
[[Page 35205]]
1404; email address: <a href="/cdn-cgi/l/email-protection#b1e5e2f2f09cf9dec5ddd8dfd4f1d4c1d09fd6dec7"><span class="__cf_email__" data-cfemail="33676070721e7b5c475f5a5d56735643521d545c45">[email protected]</span></a>.
SUPPLEMENTARY INFORMATION:
I. Executive Summary
A. Does this action apply to me?
This action provides information that is directed to the public in
general.
B. What is the Agency's authority for taking this action?
EPA is publishing this document in the Federal Register as required
by sections 5 of the Toxic Substances Control Act (TSCA), 15 U.S.C.
2601 et seq., and corresponding EPA regulations.
Under TSCA, a chemical substance may be either an ``existing''
chemical substance or a ``new'' chemical substance, see <a href="https://www.epa.gov/chemicals-under-tsca">https://www.epa.gov/chemicals-under-tsca</a>. Any chemical substance that is not on
EPA's TSCA Inventory of Chemical Substances (TSCA Inventory) is
classified as a ``new chemical substance,'' while a chemical substance
that is listed on the TSCA Inventory is classified as an ``existing
chemical substance.'' See TSCA section 3(2) and (11). For more
information about the TSCA Inventory, see <a href="https://www.epa.gov/inventory">https://www.epa.gov/inventory</a>.
Any person who intends to manufacture (including import) a new
chemical substance for a non-exempt commercial purpose, or to
manufacture or process a chemical substance in a non-exempt manner for
a use that EPA has determined is a significant new use, is required by
TSCA section 5 to provide EPA with a PMN, MCAN, or SNUN, as
appropriate, before initiating the activity. EPA will review the
notice, make a risk determination on the new chemical substance or
significant new use, and take appropriate action as described in TSCA
section 5(a)(3).
TSCA section 5(h)(1) authorizes EPA to allow persons, upon
application and under appropriate restrictions, to manufacture a new
chemical substance, or manufacture or process a chemical substance
subject to a significant new use rule (SNUR) issued under TSCA section
5(a)(2), for ``test marketing'' purposes, upon a showing that the
manufacture, processing, distribution in commerce, use, and disposal of
the chemical substances will not present an unreasonable risk of injury
to health or the environment. This is referred to as a test marketing
exemption, or TME.
Premanufacture notification procedures for review of certain new
microbial products of biotechnology are established in 40 CFR part 725.
These pertain to MCANs and biotechnology exemptions, including TSCA
experimental release applications (TERAs), TMEs for microorganisms, and
Tier I and Tier II exemptions.
C. What action is the Agency taking?
This document provides notice of receipt and status reports for the
covered period and certain submissions under TSCA section 5 and
provides an opportunity to comment on this information. The Agency is
providing information about the receipt of PMNs, SNUNs, MCANs, and
amendments to a previously submitted notice; test information;
biotechnology exemption applications under 40 CFR part 725; TME
applications; NOCs for new chemical substances; and a periodic status
report on chemical substances that are currently under EPA review or
have recently concluded review.
D. What should I consider as I prepare my comments for EPA?
1. Submitting CBI. Do not submit CBI to EPA through <a href="https://www.regulations.gov">https://www.regulations.gov</a> or email. If you wish to include CBI in your
comment, please follow the instructions at <a href="https://www.epa.gov/dockets/commenting-epa-dockets#rules">https://www.epa.gov/dockets/commenting-epa-dockets#rules</a> and clearly mark the information that you
claim to be CBI. In addition to one complete version of the comment
that includes CBI, a copy of the comment without CBI must be submitted
for inclusion in the public docket. Information marked as CBI will not
be disclosed except in accordance with procedures set forth in 40 CFR
parts 2 and 703.
2. Tips for preparing your comments. When preparing and submitting
your comments, see the commenting tips at <a href="https://www.epa.gov/dockets/commenting-epa-dockets">https://www.epa.gov/dockets/commenting-epa-dockets</a>.
II. Background
A. What information is being provided in this document?
The tables in this document provide the following information on
the TSCA section 5 submissions and amendments received by EPA during
this period and determined to be completely consistent with 40 CFR
720.70(a).
<bullet> Case number. The EPA number assigned to the TSCA section 5
submissions. Please note that a case number may be listed more than
once in the table when the submission involves a subsequent amendment.
<bullet> Chemical substance. Name of the chemical substance, or
generic name if the specific name is claimed as CBI.
<bullet> Manufacturer. Name of the submitting manufacturer, to the
extent that such information is not subject to a CBI claim. The term
``manufacturer'' is defined by statute to include importer.
<bullet> Use(s). Potential uses identified by the manufacturer.
<bullet> Received. Date the submission was received by EPA.
<bullet> Commencement. Date of commencement provided by the
submitter in the NOC.
<bullet> Test information. For test information received, the type
of test information submitted to EPA is based on the attachment type
and subtype data selected by the submitter.
B. What do the acronyms mean that are used in the tables?
As used in each of the tables, the following explanations apply:
<bullet> (S) indicates that the information in the table is the
specific information provided by the submitter.
<bullet> (G) indicates that the information in the table is generic
information because the specific information provided by the submitter
was claimed as CBI.
C. How can I access other information about TSCA section 5 submissions?
EPA provides information on its website about cases reviewed under
TSCA section 5, including the PMNs, SNUNs, MCANs, and exemption
applications received; the date of receipt; the final EPA determination
on the submission; and the effective date of EPA's determination. See
<a href="https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/pre-manufacture-notices">https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/pre-manufacture-notices</a>. In addition, information EPA
receives about chemical substances under TSCA, including non-CBI new
chemical submissions, can be accessed in ChemView at <a href="https://chemview.epa.gov/chemview">https://chemview.epa.gov/chemview</a>.
III. Receipt Reports
Table 1 provides non-CBI information for the PMNs, SNUNs and MCANs
received by EPA that have passed an initial screening and determined to
be complete consistent with 40 CFR 720.70(a) during this period.
[[Page 35206]]
Table 1--PMN/SNUN/MCANs Received and Under Review
----------------------------------------------------------------------------------------------------------------
Received
Case No. date Manufacturer Use Chemical substance
----------------------------------------------------------------------------------------------------------------
J-25-0013................. 11/19/2025 CBI.................... (G) Manufacture of an (G) Modified
industrial chemical Microorganism, with
and co-products. chromosomal
modifications to
improve fermentation
characteristics
J-25-0013................. 02/18/2026 CBI.................... (G) Manufacture of an (G) Modified
industrial chemical Microorganism, with
and co-products. chromosomal
modifications to
improve fermentation
characteristics
J-26-0001................. 01/08/2026 Lesaffre Yeast (S) The production of (G) Modified yeast for
Corporation. ethanol. improved production
of ethanol
P-21-0190................. 02/05/2026 Santolubes (S) This product will (S) Poly(oxy-1,2-
Manufacturing LLC. be used in gear oils ethanediyl)-alpha-(1-
& greases, wind oxohexyl)-omega-[(1-
turbines, HX-1 oxohexyl) oxy]-
(incidental food
contact) lubricants
and EV (Electric
Vehicle) motors. It
will be used by OEMs
in these applications
as components in
finished
formulations. The
intended use of these
products is 100%
industrial and not
intended for use as
consumer products.
P-21-0193................. 02/05/2026 Santolubes (S) This product will (S) Fatty acids, C8-
Manufacturing LLC. be used in gear oils 10, diesters with
& greases, wind polyethylene glycol
turbines, HX-1
(incidental food
contact) lubricants
and EV (Electric
Vehicle) motors. It
will be used by OEMs
in these applications
as components in
finished
formulations. The
intended use of these
products is 100%
industrial and not
intended for use as
consumer products.
P-24-0027................. 02/19/2026 Mikros Biochem......... (S) Surfactant........ (S) Fatty acids, C8-
14, 2,3-diesters with
rel-(2R, 3S)-2,3,4-
trihydroxybutyl Beta-
D-mannopyranoside
acetate
P-24-0179................. 02/19/2026 CBI.................... (G) Component in (G) Aluminum- and
batteries. metal-doped cobalt
metal nickel oxide
P-24-0180................. 02/19/2026 CBI.................... (G) Component in (G) Aluminum- and
batteries. metal- and metal-
doped cobalt metal
nickel oxide
P-24-0181................. 02/19/2026 CBI.................... (G) Component in (G) Metal- and metal-
batteries. doped cobalt metal
metal nickel oxide
P-24-0188................. 02/10/2026 CBI.................... (G) Component in (G) Cobalt metal metal
batteries. nickel zirconium
doped
P-24-0195................. 02/02/2026 CBI.................... (G) Heat transfer (G) Trimers of
fluid, Dielectric hexafluoropropene
testing.
P-25-0023................. 02/25/2026 CBI.................... (G) Mixed metal oxide (G) Cobalt lithium
for batteries. manganese nickel
oxide, metals-
modified
P-25-0118................. 02/02/2026 CBI.................... (G) Liquid formulation (G) Neutral Protease
of biocatalyst used
in a variety of
products; solid
formulation of
biocatalyst used in a
variety of products.
P-26-0036................. 02/17/2026 CBI.................... (S) Lubricating oil (G) Amines,
additive. polyalkylenepoly,
reaction products
with succinnic
anhydride,
polyalkenyl derivs.
compounds with
metaloxy acid
P-26-0038................. 02/24/2026 Mojia, Inc............. (G) Industrial (G) Aliphatic
reactant. diisocyanate
P-26-0049................. 02/12/2026 H.B. Fuller Company.... (S) 25MM01 is for (G) Carbon monocyclic
adhering recreational diacid with
vehicle parts during dodecanedioic acid,
manufacturing. hexanedioic acid,
alpha-hydro-omega-
hydroxypoly[oxy(methy
l-1,2-ethanediyl)],
1,3-
isobenzofurandione,
1,1'-methylenbis[4-
isocyanatobenzene]
and tetradecanedioic
acid
P-26-0050................. 02/12/2026 H.B. Fuller Company.... (S) 25MM01 is for (G) Carbon monocyclic
adhering recreational diacid with
vehicle parts during dodecanedioic acid,
manufacturing. hexanedioic acid,
alpha-hydro-omega-
hydroxypoly[oxy(methy
l-1,2-ethanediyl)],
1,3-
isobenzofurandione,
1,1'-
methylenbis[isocyanat
obenzene] and
tetradecanedioic acid
P-26-0051................. 02/12/2026 H.B. Fuller Company.... (S) 25MM01 is for (G) Carbon monocyclic
adhering recreational diacid with
vehicle parts during dodecanedioic acid,
manufacturing. alkyldioic acid, 1,4-
butanediol,
hexanedioic acid,
alpha-hydro-omega-
hydroxypoly[oxy(methy
l-1,2-ethanediyl)],
1,3-
isobenzofurandione,
1,1'-methylenbis[4-
isocyanatobenzene]
and tetradecanedioic
acid
[[Page 35207]]
P-26-0052................. 02/12/2026 H.B. Fuller Company.... (S) 25MM01 is for (G) Carbon monocyclic
adhering recreational diacid with
vehicle parts during dodecanedioic acid,
manufacturing. alkyldioic acid, 1,4-
butanediol,
hexanedioic acid,
alpha-hydro-omega-
hydroxypoly[oxy(methy
l-1,2-ethanediyl)],
1,3-
isobenzofurandione,
1,1'-
methylenbis[isocyanat
obenzene] and
tetradecanedioic acid
P-26-0053................. 02/12/2026 H.B. Fuller Company.... (S) 25MM01 is for (G) Carbon monocyclic
adhering recreational diacid with
vehicle parts during dodecanedioic acid,
manufacturing. hexanedioic acid,
dihydro-heterocyclic
Dione, alpha-hydro-
omega-
hydroxypoly[oxy(methy
l-1,2-ethanediyl)],
1,3-
isobenzofurandione,
1,1'-methylenbis[4-
isocyanatobenzene]
and tetradecanedioic
acid
P-26-0054................. 02/12/2026 H.B. Fuller Company.... (S) 25MM01 is for (G) Carbon monocyclic
adhering recreational diacid with
vehicle parts during dodecanedioic acid,
manufacturing. hexanedioic acid,
dihydro-heterocyclic
Dione, alpha-hydro-
omega-
hydroxypoly[oxy(methy
l-1,2-ethanediyl)],
1,3-
isobenzofurandione,
1,1'-
methylenbis[isocyanat
obenzene] and
tetradecanedioic acid
P-26-0055................. 02/09/2026 Sachem, Inc............ (G) Processing aid (G)
used in chemical polyalkylalkanediammo
synthesis/ nium hydroxide
manufacture..
P-26-0055................. 02/17/2026 Sachem, Inc............ (G) Processing aid (G)
used in chemical polyalkylalkanediammo
synthesis/ nium hydroxide
manufacture..
P-26-0057................. 02/10/2026 CBI.................... (G) Component of (G) Alkyl alkenoic
coating, Component of acid,
printing formulation. (trialkoxymetalloid)a
lkyl ester,
hydrolysis products
with silica and
polyalkyl substituted
amine
P-26-0058................. 02/11/2026 Schimmer & Schwarz..... (S) Raw material in (G) Isomerized alkane
ester manufacturing, derivatives
to be fully consumed.
P-26-0059................. 02/24/2026 Integrated Chemical (S) CONDITIONER is (S) 2-Propen-1-one, 2-
Technologies, Inc. added to hydrochloric (methoxymethyl)-1-
acid to provide phenyl
corrosion inhibition
of steel and other
metallurgies. Typical
dosage ranges between
5-20 gallons of
Conditioner per 1000
gallons of 15wt% HCl..
SN-25-0010................ 02/02/2026 Solstice Advanced (S) NEW USE: MVAC- (S) 1-Propene, 2,3,3,3-
Materials US, Inc. Passenger Air tetrafluoro-
Conditioning in light
duty vehicles that
were previously using
R-134a as their
refrigerant: 1. light-
duty vehicles (e.g.,
passenger cars) 2.
light- duty trucks
(e.g., minivans, full
size pick-up trucks,
and full-size SUVs)
3. medium-duty
passenger vehicles,
heavy-duty pickup
trucks, complete
heavy-duty vans (G)
Refrigerant.
----------------------------------------------------------------------------------------------------------------
Table 2 provides non-CBI information on the NOCs received by EPA
that have passed an initial screening during this period.
Table 2--NOCs Received and Under Review
------------------------------------------------------------------------
Received Commencement
Case No. date date Chemical substance
------------------------------------------------------------------------
P-15-0554.......... 02/24/2026 02/05/2026 (G) Dialkylamino
alkylamide salt
P-22-0114.......... 02/13/2026 08/27/2025 (G) edge-oxidized
carbon matrix
P-22-0181.......... 02/17/2026 01/20/2026 (S) Fatty acids, C18-
unsatd., dimers,
polymers with
erucic acid-low
rape-oil fatty
acids and
polyethylene glycol
ether with glycerol
(3:1)
P-24-0006.......... 02/17/2026 02/11/2026 (G) polymeric salt
of propenoic acid,
acrylamido-
methylpropane
sulfonic acid
sodium salt,
hydroxyethyl
methacrylate,
methyl
methacrylate,
propenoic acid,
methyl-,
phosphinicobis(oxy-
ethanediyl) ester,
sodium
metabisulfite
P-24-0069.......... 02/06/2026 01/13/2025 (G) Oxa-thiaspiro
alkane, oxide
P-24-0093.......... 02/23/2026 01/31/2026 (S) Rhamnolipids,
Pseudomonas putida
strain BS-PP-484-
fermented, from D-
glucose, potassium
salts
P-24-0094.......... 02/23/2026 01/31/2026 (S) Rhamnolipids,
Pseudomonas putida
strain BS-PP-484-
fermented, from D-
glucose, sodium
salts
P-24-0095.......... 02/23/2026 01/31/2026 (S) Rhamnolipids,
Pseudomonas allo
utida mt-2 KT 2440
strain BS-PP 555-
fermented, from D-
glucose, potassium
salt
[[Page 35208]]
P-24-0096.......... 02/23/2026 01/31/2026 (S) Rhamnolipids,
Pseudomonas allo
utida mt-2 KT 2440
strain BS-PP 555-
fermented, from D-
glucose, sodium
salt
P-24-0122.......... 02/02/2026 01/26/2026 (G) Sulfonium,
polyphenyl
(substituted
phenyl)
alkylbenzenesulfona
te,
------------------------------------------------------------------------
Table 3 provides non-CBI information on the test information that
has been received by EPA that has passed an initial screening during
this period.
Table 3--Test Information Received
------------------------------------------------------------------------
Received Type of test Chemical
Case No. date information substance
------------------------------------------------------------------------
P-16-0543............ 02/16/2026 Monitoring Report (G)
Halogenophosphor
ic acid metal
salt
P-18-0281............ 02/02/2026 Monitoring Report (G) Cyclic
sulfate
P-19-0166............ 02/24/2026 Hydrolysis as a (G) Triaryl
Function of pH sulfonium,
(OECD Test multicycloalkyla
Guideline 111); lkoxycarbonyloxy
Partition monofluoroalkyls
Coefficient (1- ulfonate
Octanol/Water):
Slow-Stirring
Method (OECD
Test Guideline
123); Photo
transformation
of Chemicals in
Water--Direct
Photolysis (OECD
Test Guideline
316).
P-23-0093............ 02/20/2026 Notice of (G) Aromatic
scheduling. Dibenz
thiophenium
fluoroalkyl
carbopolycycle
sulfonic acid
salt
P-24-0160............ 02/20/2026 Notice of (G) Iodonium, bis
scheduling. (dialkyl
carbomonocycle)
salt with alkyl
carbomonocycle
hetero acid
P-24-0190............ 02/20/2026 Notice of (G) Aromatic
scheduling. sulfonium
tricyclo salt
with alkyl
carbomonocycle
hetero acid
P-25-0016............ 02/20/2026 Notice of (G) Tri
scheduling. haloaromatic
iodonium dicyclo
salt with
polyhaloalkyl
carbomonocycle
hetero acid
P-25-0097............ 02/20/2026 Notice of (G) Aromatic
scheduling. sulfonium
tricyclo salt
with Carbopol
cycloalkyl ester
polysubstituteda
rylhetero-acid
P-25-0100............ 02/20/2026 Notice of (G) Aromatic
scheduling. sulfonium
tricyclo salt
with alkyl
carbomonocycle
hetero acid
P-25-0102............ 02/20/2026 Notice of (G)
scheduling. Carboheterocyclo
aromatic
sulfonium salt
with
dicycloalkyl
carbomonocycle
hetero acid
P-25-0111............ 02/20/2026 Notice of (G) Haloaromatic
scheduling. iodonium dicyclo
salt with
polyhaloalkyl
carbomonocycle
hetero acid
P-25-0112............ 02/20/2026 Notice of (G) Haloaromatic
scheduling. iodonium dicyclo
salt with
halogenated
hydroxyaryl
carboxylic acid
P-25-0124............ 02/20/2026 Notice of (G) Alkyl
scheduling. aromatic
sulfonium,
polycyclic alkyl
sulfamate
------------------------------------------------------------------------
IV. Status Reports
Information about the TSCA section 5 PMNs, SNUNs, MCANs, and
exemption applications received, including the date of receipt, the
status of EPA's review, the final EPA determination, and the effective
date of EPA's determination, is available online at: <a href="https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/pre-manufacture-notices">https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/pre-manufacture-notices</a>.
Authority: 15 U.S.C. 2601 et seq.
Dated: June 5, 2026.
Mary Elissa Reaves,
Director, Office of Pollution Prevention and Toxics.
[FR Doc. 2026-11591 Filed 6-9-26; 8:45 am]
BILLING CODE 6560-50-P
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