Notice2026-11318
Certain New Chemicals; Receipt and Status Information for November 2025, December 2025, and January 2026
Primary source
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Published
June 5, 2026
Issuing agencies
Environmental Protection Agency
Abstract
This document announces the Agency's receipt of new chemical submissions under the Toxic Substances Control Act (TSCA), including information about the receipt of a Premanufacture Notice (PMN), Significant New Use Notice (SNUN), Microbial Commercial Activity Notice (MCAN), and an amendment to a previously submitted notice; test information; a biotechnology exemption application; an application for a test marketing exemption (TME); and a notice of commencement of manufacture (defined by statute to include import) (NOC) for a new chemical substance. This document also provides a periodic status report on the new chemical substances that are currently under EPA review or have recently concluded review. EPA is hereby providing notice of receipt of this information, as required by TSCA, and an opportunity to comment. This document covers new chemical submissions that have passed an initial screening and, for PMNs, SNUNs and MCANs, were determined to be complete, during the period from 1/1/2026 to 1/ 31/2026 regardless of the initial submission date.
Full Text
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<title>Federal Register, Volume 91 Issue 108 (Friday, June 5, 2026)</title>
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[Federal Register Volume 91, Number 108 (Friday, June 5, 2026)]
[Notices]
[Pages 34233-34239]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2026-11318]
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ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-OPPT-2026-1387; FRL-13202-01-OCSPP]
Certain New Chemicals; Receipt and Status Information for
November 2025, December 2025, and January 2026
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of receipt and request for comment.
-----------------------------------------------------------------------
SUMMARY: This document announces the Agency's receipt of new chemical
submissions under the Toxic Substances Control Act (TSCA), including
information about the receipt of a Premanufacture Notice (PMN),
Significant New Use Notice (SNUN), Microbial Commercial Activity Notice
(MCAN), and an amendment to a previously submitted notice; test
information; a biotechnology exemption application; an application for
a test marketing exemption (TME); and a notice of commencement of
manufacture (defined by statute to include import) (NOC) for a new
chemical substance. This document also provides a periodic status
report on the new chemical substances that are currently under EPA
review or have recently concluded review. EPA is hereby providing
notice of receipt of this information, as required by TSCA, and an
opportunity to comment. This document covers new chemical submissions
that have passed an initial screening and, for PMNs, SNUNs and MCANs,
were determined to be complete, during the period from 1/1/2026 to 1/
31/2026 regardless of the initial submission date.
DATES: Comments must be received on or before July 6, 2026.
ADDRESSES: Submit your comments, identified by docket identification
(ID) number EPA-HQ-OPPT-2026-1387 and the specific case number provided
in this document for the chemical substance related to your comment,
online at <a href="https://www.regulations.gov">https://www.regulations.gov</a>. Follow the online instructions
for submitting comments. Do not submit electronically any information
you consider to be Confidential Business Information (CBI) or other
information whose disclosure is restricted by statute. Additional
instructions on commenting on and visiting the docket, along with more
information about dockets generally, are available at <a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>.
FOR FURTHER INFORMATION CONTACT:
For technical information: Jim Rahai, Office of Chemical Safety and
Pollution Prevention (OCSPP-OMCO-RISD), Environmental Protection
Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-0001; telephone
number: (202) 564-8593; email address: <a href="/cdn-cgi/l/email-protection#bfcdded7ded691d5d6d2ffdacfde91d8d0c9"><span class="__cf_email__" data-cfemail="4331222b222a6d292a2e032633226d242c35">[email protected]</span></a>.
For general information: The TSCA-Hotline, ABVI-Goodwill, 422 South
Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404;
email address: <a href="/cdn-cgi/l/email-protection#affbfcecee82e7c0dbc3c6c1caefcadfce81c8c0d9"><span class="__cf_email__" data-cfemail="32666171731f7a5d465e5b5c57725742531c555d44">[email protected]</span></a>.
SUPPLEMENTARY INFORMATION:
I. Executive Summary
A. Does this action apply to me?
This action provides information that is directed to the public in
general.
B. What is the Agency's authority for taking this action?
EPA is publishing this document in the Federal Register as required
by sections 5 of the Toxic Substances Control Act (TSCA), 15 U.S.C.
2601 et seq., and corresponding EPA regulations.
Under TSCA, a chemical substance may be either an ``existing''
chemical substance or a ``new'' chemical substance, see <a href="https://www.epa.gov/chemicals-under-tsca">https://www.epa.gov/chemicals-under-tsca</a>. Any chemical substance that is not on
EPA's TSCA Inventory of Chemical Substances (TSCA Inventory) is
classified as a ``new chemical substance,'' while a chemical substance
that is listed on the TSCA Inventory is classified as an ``existing
chemical substance.'' See TSCA section 3(2) and (11). For more
information about the TSCA Inventory, see <a href="https://www.epa.gov/inventory">https://www.epa.gov/inventory</a>.
Any person who intends to manufacture (including import) a new
chemical substance for a non-exempt commercial purpose, or to
manufacture or process a chemical substance in a non-exempt manner for
a use that EPA has determined is a significant new use, is required by
TSCA section 5 to provide EPA with a PMN, MCAN, or SNUN, as
appropriate, before initiating the activity. EPA will review the
notice, make a risk determination on the new chemical substance or
significant new use, and take appropriate action as described in TSCA
section 5(a)(3).
TSCA section 5(h)(1) authorizes EPA to allow persons, upon
application and under appropriate restrictions, to manufacture a new
chemical substance, or manufacture or process a chemical
[[Page 34234]]
substance subject to a significant new use rule (SNUR) issued under
TSCA section 5(a)(2), for ``test marketing'' purposes, upon a showing
that the manufacture, processing, distribution in commerce, use, and
disposal of the chemical substances will not present an unreasonable
risk of injury to health or the environment. This is referred to as a
test marketing exemption, or TME.
Premanufacture notification procedures for review of certain new
microbial products of biotechnology are established in 40 CFR part 725.
These pertain to MCANs and biotechnology exemptions, including TSCA
experimental release applications (TERAs), TMEs for microorganisms, and
Tier I and Tier II exemptions.
C. What action is the Agency taking?
This document provides notice of receipt and status reports for the
covered period and certain submissions under TSCA section 5 and
provides an opportunity to comment on this information. The Agency is
providing information about the receipt of PMNs, SNUNs, MCANs, and
amendments to a previously submitted notice; test information;
biotechnology exemption applications under 40 CFR part 725; TME
applications; NOCs for new chemical substances; and a periodic status
report on chemical substances that are currently under EPA review or
have recently concluded review.
D. What should I consider as I prepare my comments for EPA?
1. Submitting CBI. Do not submit CBI to EPA through <a href="https://www.regulations.gov">https://www.regulations.gov</a> or email. If you wish to include CBI in your
comment, please follow the instructions at <a href="https://www.epa.gov/dockets/commenting-epa-dockets#rules">https://www.epa.gov/dockets/commenting-epa-dockets#rules</a> and clearly mark the information that you
claim to be CBI. In addition to one complete version of the comment
that includes CBI, a copy of the comment without CBI must be submitted
for inclusion in the public docket. Information marked as CBI will not
be disclosed except in accordance with procedures set forth in 40 CFR
parts 2 and 703.
2. Tips for preparing your comments. When preparing and submitting
your comments, see the commenting tips at <a href="https://www.epa.gov/dockets/commenting-epa-dockets">https://www.epa.gov/dockets/commenting-epa-dockets</a>.
II. Background
A. What information is being provided in this document?
The tables in this document provide the following information on
the TSCA section 5 submissions and amendments received by EPA during
this period and determined to be completely consistent with 40 CFR
720.70(a).
<bullet> Case number. The EPA number assigned to the TSCA section 5
submissions. Please note that a case number may be listed more than
once in the table when the submission involves a subsequent amendment.
<bullet> Chemical substance. Name of the chemical substance, or
generic name if the specific name is claimed as CBI.
<bullet> Manufacturer. Name of the submitting manufacturer, to the
extent that such information is not subject to a CBI claim. The term
``manufacturer'' is defined by statute to include importer.
<bullet> Use(s). Potential uses identified by the manufacturer.
<bullet> Received. Date the submission was received by EPA.
<bullet> Commencement. Date of commencement provided by the
submitter in the NOC.
<bullet> Test information. For test information received, the type
of test information submitted to EPA is based on the attachment type
and subtype data selected by the submitter.
B. What do the acronyms mean that are used in the tables?
As used in each of the tables, the following explanations apply:
<bullet> (S) Indicates that the information in the table is the
specific information provided by the submitter.
<bullet> (G) Indicates that the information in the table is generic
information because the specific information provided by the submitter
was claimed as CBI.
C. How can I access other information about TSCA section 5 submissions?
EPA provides information on its website about cases reviewed under
TSCA section 5, including the PMNs, SNUNs, MCANs, and exemption
applications received; the date of receipt; the final EPA determination
on the submission; and the effective date of EPA's determination.
<a href="https://www.epa.gov/new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices">https://www.epa.gov/new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices</a>. In addition, information EPA
receives about chemical substances under TSCA, including non-CBI new
chemical submissions, can be accessed in ChemView at <a href="https://chemview.epa.gov/chemview">https://chemview.epa.gov/chemview</a>.
III. Receipt Reports
Table 1 provides non-CBI information for the PMNs, SNUNs and MCANs
received by EPA that have passed an initial screening and determined to
be complete consistent with 40 CFR 720.70(a) during this period.
Table 1--PMN/SNUN/MCANs Received and Under Review
----------------------------------------------------------------------------------------------------------------
Received
Case No. date Manufacturer Use Chemical substance
----------------------------------------------------------------------------------------------------------------
J-25-0012............. 12/16/2025 Valent Biosciences, LLC....... (G) Manufacture (G) Strain of
for use in Streptomyces cyaneo
production of fuscatus modified with
natural compound, genetically stable,
consistent with DNA insertion
the responsible for the
manufacturing, production of a
processing, use, modified enzyme.
distribution, and
disposal
information
described in the
MCAN.
P-22-0071............. 01/15/2026 CBI........................... (G) Industrial (S) D-Glucopyranose,
Surfactant. oligomeric, maleates,
C9-11-alkyl
glycosides,
sulfonated, potassium
salts.
P-22-0072............. 01/15/2026 CBI........................... (G) Industrial (S) D-Glucopyranose,
Surfactant. oligomeric, maleates,
decyl octyl
glycosides,
sulfonated, potassium
salts.
P-22-0073............. 01/15/2026 CBI........................... (G) Industrial (S) D-Glucopyranose,
Surfactant. oligomeric, maleates,
C10-16-alkyl
glycosides,
sulfonated, potassium
salts.
P-23-0022............. 01/26/2026 Cabot Corporation............. (G) Import only in (G) Multi-walled carbon
liquid/dispersion nanotubes.
form for additive
used in
industrial
applications.
P-23-0023............. 01/26/2026 Cabot Corporation............. (G) Additive used (G) Multi-walled carbon
in industrial nanotubes.
applications.
P-23-0024............. 01/26/2026 Cabot Corporation............. (G) Additive used (G) Multi-walled carbon
in industrial nanotubes.
applications.
P-24-0137............. 01/12/2026 CBI........................... (G) Component of (G) Alkene, reaction
liquid detergent. products with oxide,
hydrolyzed, alkali
metal salts.
[[Page 34235]]
P-24-0195............. 01/27/2026 CBI........................... (G) Heat transfer (G) Trimers of
fluid, Dielectric hexafluoropropene.
testing.
P-25-0073............. 01/07/2026 CBI........................... (G) Substance for (G) Cobalt lithium
the use in manganese nickel
manufacturing of oxide, metals.
battery
components.
P-25-0125............. 01/19/2026 CBI........................... (G) Substance for (G) Cobalt lithium
the use in manganese nickel
manufacturing of oxide, metals.
battery
components.
P-25-0151............. 01/12/2026 CBI........................... (G) Substance for (G) Cobalt lithium
the use in manganese nickel
manufacturing of oxide, metals.
battery
components.
P-25-0152............. 01/12/2026 CBI........................... (G) Substance for (G) Cobalt lithium
the use in manganese nickel
manufacturing of oxide, metals.
battery
components..
P-26-0024............. 01/20/2026 CBI........................... (G) Lubricating (G) Maleated
oil additive. polyalkene, aminoethyl
substituted
hereromonocycle,
carbopolycycle
alkoxylated.
P-26-0027............. 11/19/2025 IGM Resins USA, Inc........... (S) Photo (S) Methanone, 1,1'-
initiator and co- (octylphosphinylidene)
initiator used in bis[1-(2,4,6-
adhesives, trimethylphenyl)-.
coatings, and
inks.
P-26-0028............. 01/05/2026 Eastman Chemical Company, Inc. (G) chemical (G) Depolymerized waste
intermediate. plastics.
P-26-0030............. 01/07/2026 CBI........................... (G) Chemical (G) Waste plastics,
intermediate for poly (ethylene
polyurethane terephthalate),
industry. depolymd. with
glycols.
P-26-0030............. 01/21/2026 CBI........................... (G) Chemical (G) Waste plastics,
intermediate for poly (ethylene
polyurethane terephthalate),
industry.. depolymd. with
glycols.
P-26-0032............. 01/07/2026 CBI........................... (G) Component in (G) Oxirane,
coating product. alkylidenebis
(substituted aromatic)
bis-, polymer with
substituted
alkoxylated
cycloalkane.
P-26-0039............. 01/05/2026 Cargill, Incorporated......... (S) The substance (S) Fatty acids, C12-18
is used as an and C18-unsatd.,
anti-fogging esters with sorbitol,
additive dehydrated.
incorporated into
Polyethylene (PE)
and Ethylene
Vinyl Acetate
(EVA) films to
increase
transparency of
food and other
packaging. The
PMN substance can
also be
incorporated into
a resin or a
masterbatch/pre-
blend that is
used in
automotive
coatings,
industrial
coatings, and
film production.
P-26-0040............. 01/05/2026 CBI........................... (G) Commodity (G) Alkyl fatty acids
chemical reaction products with
manufacture. amino hydroxyalkyl
amine.
P-26-0043............. 01/20/2026 CBI........................... (G) Plastic resin. (G) Alkanoic acid,
substituted, polymer
with substituted
alkanoic acid, from
fermentation of
fermentable sugars.
P-26-0044............. 01/20/2026 CBI........................... (G) Plastic Resin. (G) Alkanoic acid,
substituted, polymer
with substituted
alkanoic acid, from
fermentation of
fermentable oils.
P-26-0045............. 01/07/2026 CBI........................... (S) Export (G) Aromatic carboxylic
formulated acid, Halogenated
product for use heteromonocycle ester,
outside of US, polymer with:
(G) Photoacid Haloaromatic iodonium
generator use at tricyclo salt with
customer. polyhaloalkyl
carbomonocycle hetero
acid, modified.
P-26-0046............. 01/13/2026 CBI........................... (G) Electronic (G) Fluorinated alkene.
component
manufacturing.
P-26-0047............. 01/20/2026 CBI........................... (G) Substance for (G) Metals phosphate,
use in the modified.
manufacture of
batteries.
P-26-0047............. 01/28/2026 CBI........................... (G) Substance for (G) Metals phosphate,
use in the modified.
manufacture of
batteries.
P-26-0048............. 01/23/2026 CBI........................... (G) An ingredient (G)
used in the Carbomonocyclicsulfoni
manufacture of c acid, polyhalo-,
photoresist. alkylpolyoxoheteropoly
cyclic ester.
SN-26-0002............ 01/19/2026 CBI........................... (G) Substance for (S) Phosphoric acid,
use in the iron (2+) lithium salt
manufacture of (1:1:1).
batteries.
----------------------------------------------------------------------------------------------------------------
In Table II of this unit, EPA provides the following information
(to the extent that such information is not claimed as CBI) on the NOCs
that have passed an initial screening by EPA during this period: The
EPA case number assigned to the NOC including whether the submission
was an initial or amended submission, the date the NOC was received by
EPA, the date of commencement provided by the submitter in the NOC, and
chemical substance identity.
Table 2 provides non-CBI information on the NOCs received by EPA
that have passed an initial screening during this period.
Table 2--NOCs Received and Under Review
----------------------------------------------------------------------------------------------------------------
Received Commencement
Case No. date date Chemical substance
----------------------------------------------------------------------------------------------------------------
P-21-0104................................. 01/21/2026 12/19/2025 (G) Alkandioic acid di branched alkyl
esters.
[[Page 34236]]
P-21-0105................................. 01/21/2026 12/19/2025 (G) Alkandioic acid di C11-14 iso alkyl
esters.
P-22-0089................................. 01/28/2026 01/20/2026 (G) Carboxylic acid substituted
carbomonocycles, polymer with dialkyl-
alkanediol and alkanediol, hydroxy-
alkyl-oxo-alkenyl) oxy] alkyl ester.
P-22-0091................................. 01/28/2026 01/20/2026 (G) Alkanol, polymer with isocyanato-
(isocyanatoalkyl)-
trialkylcarbomonocycle, alkylene
glycol monoacrylate-blocked.
P-23-0038................................. 01/28/2026 01/19/2026 (G) Formaldehyde, polymer with phenol,
carboxyalkyl ethers, alkali salts,
compds. with (dialkylamino) alkanol.
P-23-0064................................. 01/07/2026 12/09/2025 (G) Alkanediol, substituted, polymer
with diisocyanatoalkane, substituted
heterocycle-modified.
P-24-0102................................. 01/20/2026 10/02/2025 (G) Alkane diacid polymer with
alkanediol, polybutylene glycol and
1,1'-methylenebis[4-
isocyanatobenzene].
P-24-0103................................. 01/20/2026 10/05/2025 (G) Alkane diacid polymer with
alkanediol, polybutylene glycol and
1,1'-methylenebis[isocyanatobenzene].
----------------------------------------------------------------------------------------------------------------
Table 3 provides non-CBI information on the test information that
has been received by EPA that has passed an initial screening during
this period.
Table 3--Test Information Received
------------------------------------------------------------------------
Received Type of test Chemical
Case No. date information substance
------------------------------------------------------------------------
P-14-0712.............. 01/05/2026 Q4 2025 Sample (S) Waste
Testing Notice plastics,
Using EPA pyrolyzed, C5-
Method 8290A. 55 fraction.
P-17-0178.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triphenyl-,
(OECD Test salt with
Guideline 111). substituted-
alkyl 4-
substituted-
benzoate.
P-18-0013.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH pheno
(OECD Test carbopolycycle,
Guideline 111). inner salt.
P-18-0014.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triphenyl-,
(OECD Test salt with
Guideline 111). disubstituted-
heterocyclic
compound (1:1).
P-18-0016.............. 01/27/2026 Hydrolysis as a (G) Aromatic
Function of pH sulfonium
(OECD Test tricyclo
Guideline 111). fluoroalkyl
sulfonic acid
salt.
P-18-0037.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triphenyl-,
(OECD Test salt with 2,4,5-
Guideline 111). trisubstituted-
benzenesulfonat
e (1:1).
P-18-0281.............. 01/15/2026 Exposure (G) Cyclic
Monitoring sulfate.
Report.
P-18-0304.............. 01/22/2026 Hydrolysis as a (G) Sulfonium,
Function of pH bis (dihalo
(OECD Test carbomonocycle)
Guideline 111). carbomonocycle,
salt with
substituted
heteropolycycle
dihalo sulfo
alkanoate
(1:1).
P-18-0316.............. 01/22/2026 Hydrolysis as a (G)
Function of pH Heteropolycycle
(OECD Test , alkylaromatic-
Guideline 111). , salt with
dihalo-
substituted
alkyl
carbopolycycle
carboxylate.
P-18-0338.............. 01/22/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triaryl-, salt
(OECD Test with polyhalo-4-
Guideline 111). sulfoalkyl
polycarbocyclic
alkane-1-
carboxylate
(1:1).
P-19-0076.............. 01/22/2026 Hydrolysis as a (G) Sulfonium,
Function of pH bis (dihalo
(OECD Test carbomonocycle)
Guideline 111). carbomonocycle,
salt with
dihalo
substituted
alkyl
carbopolycyclic
carboxylate
(1:1).
P-19-0078.............. 01/20/2026 Hydrolysis as a (G) Substituted
Function of pH heterocyclic
(OECD Test onium compound,
Guideline 111). salt with 2,2,2-
trifluoro-1-
(sulfomethyl)-1-
(trifluoromethy
l)ethyl 3-[(2-
methyl-1-oxo-2-
propen-1-
yl)oxy]tricycle
[3.3.1.13,7]dec
ane-1-
carboxylate
(1:1), polymer
with
acenaphthylene,
1-ethenyl-4-[(1-
ethylcyclopenty
l)oxy]benzene
and 4-
ethenylphenol,
di-Me 2,2'-(1,2-
diazenediyl)bis
[2-
methylpropanoat
e]-initiated.
P-19-0079.............. 01/20/2026 Hydrolysis as a (G) Substituted
Function of pH heterocyclic
(OECD Test onium compound,
Guideline 111). salt with 2,2,2-
trifluoro-1-
(sulfomethyl)-1-
(trifluoromehyl
)ethyl 3-[(2-
methyl-1-oxo-2-
propen-1-
yl)oxy]tricyclo
[3.3.1.13,7]dec
ane-1-
carboxylate
(1:1), polymer
with
acenaphthylene,
1-ethenyl-4-[[1-
(1-
methylethyl)cyc
lopentyl]oxy]be
nzene and 4-
ethenylphenol,
di-Me 2,2'-(1,2-
diazenediyl)bis
[2-
methylpropanoat
e]-initiated.
P-19-0111.............. 01/20/2026 Hydrolysis as a (G) Dibenz
Function of pH thiophenium,
(OECD Test trifluoro-
Guideline 111). hydroxy-
(triheterosubst
itutedalkyl)
alkanoate
(1:1).
[[Page 34237]]
P-19-0112.............. 01/20/2026 Hydrolysis as a (G) Substituted
Function of pH heterocyclic
(OECD Test onium compound,
Guideline 111). salt with 1-
(difluorosulfom
ethyl)-2,2,2-
trifluoroethyl
3-[(2-methyl-1-
oxo-2-propen-1-
yl)oxy]tricyclo
[3.3.1.13,7]dec
ane-1-
carboxylate
(1:1), polymer
with 3-
etheylphenol, 1-
(1-
methylethyl)cyc
lopentyl 2-
methyl-2-
propenoate and
1-(7-
oxabicyclo[2.2.
1]hept-2-
yl)cyclopentyl
2-methyl-2-
propenoate, di-
Me 2,2'-(1,2-
diazenediyl)bis
[2-
methylpropenoat
e]-initiated.
P-19-0114.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triphenyl-,
(OECD Test trifluoro-
Guideline 111). hydroxy-
(triheterosubst
itutedalkyl)
alkanoate
(1:1).
P-19-0115.............. 01/22/2026 Hydrolysis as a (G) Sulfonium,
Function of pH bis (dihalo
(OECD Test carbomonocycle)
Guideline 111). carbomonocycle,
substituted
carbomonocyclic
ester.
P-19-0133.............. 01/20/2026 Hydrolysis as a (G)
Function of pH Heterodisubstit
(OECD Test uted-bile acid,
Guideline 111). 1-
(difluorosulfom
ethyl)-2,2,2-
trifluoroethyl
ester, ion (1-
), (5)-,
triphenylsulfon
ium (1:1).
P-19-0166.............. 01/22/2026 Phototransformat (G) Triaryl
ion of sulfonium,
Chemicals in multicycloalkyl
Water--Direct alkoxycarbonylo
Photolysis xymonofluoroalk
(OECD Test ylsulfonate
Guideline 316);
Partition
Coefficient (1-
Octanol/Water):
Slow-Stirring
Method (OECD
Test Guideline
123);
Hydrolysis as a
Function of pH
(OECD Test
Guideline 111).
P-20-0042.............. 01/27/2026 Hydrolysis as a (G) Sulfonium,
Function of pH trisaryl-, 7,7-
(OECD Test dialkyl-2-
Guideline 111). heteropolycycli
c -1-
alkanesulfonate
(1:1).
P-20-0120.............. 01/22/2026 Hydrolysis as a (G)
Function of pH Carbomonocyclic
(OECD Test sulfonium, salt
Guideline 111). with trihalo-
sulfoalkyl
hydroxycarbopol
ycyclic
carboxylate.
P-20-0122.............. 01/20/2026 Hydrolysis as a (G) Heterocyclic
Function of pH onium compound
(OECD Test with fluoro
Guideline 111). substitutedalky
l 2-methyl-2-
propenoate
(1:1), polymer
with
acenaphthylene,
4-ethenyl-
alpha,
alphadimethylbe
nzenemethanol
and 4-
ethenylphenyl
acetate,
hydrolyzed.
P-20-0139.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triphenyl-, 1,2-
(OECD Test fluoroalkyltric
Guideline 111). ycloalkyl-1-
carboxylate
(1:1).
P-20-0140.............. 01/20/2026 Hydrolysis as a (G) N-
Function of pH Substituted-
(OECD Test beta-alanine,
Guideline 111). heterosubstitut
ed-alkyl ester,
ion (1-),
triphenylsulfon
ium (1:1).
P-20-0141.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH [4-(1,1-
(OECD Test dimethylethyl)
Guideline 111). phenyl]
diphenyl-, salt
with
heterosubstitut
ed-alkyl
tricycloalkane-
carboxylate
(1:1).
P-20-0142.............. 01/20/2026 Hydrolysis as a (G) Dibenz
Function of pH thiophenium, 5-
(OECD Test phenyl-, salt
Guideline 111). with 2,2-
difluoro-2-
sulfoethyl
substituted-
heterotricycloa
lkane-
carboxylate
(1:1).
P-20-0145.............. 01/20/2026 Hydrolysis as a (G) Substituted
Function of pH heterocyclic
(OECD Test onium compound,
Guideline 111). salt with
fluoropoly
substitutedalky
l
substitutedtric
ycloalkane
carboxylate
(1:1), polymer
with
disubstituted
aromatic
compound and 1-
methylcyclopent
yl 2-methyl-2-
propenoate, di-
Me 2,2'-(1,2-
diazenediyl)
bis[2-
methylpropanoat
e]-initiated.
P-20-0147.............. 01/20/2026 Hydrolysis as a (G) Substituted-
Function of pH 2H-
(OECD Test thiopyrylium,
Guideline 111). salt with
fluoroalkyl
tricycloalkane-
carboxylate
(1:1).
P-20-0152.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triphenyl-,
(OECD Test salt with 2,2-
Guideline 111). dihalo-2-
sulfoethyl-2-
oxo substituted
-heterotriccloa
lkane-
heteropolycycle-
carboxylate
(1:1).
P-20-0155.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triphenyl-,
(OECD Test salt with 5-
Guideline 111). alkyl- 2-alkyl-
4-(2,4,6-
substituted tri-
carbomonocycle,
hetero-acid)
benzenesulfonat
e (1:1).
P-20-0159.............. 01/20/2026 Hydrolysis as a (G)
Function of pH Phenoxathiinium
(OECD Test , 10-phenyl, 5-
Guideline 111). alkyl-2-alkyl-4-
(2,4,6-
substituted tri-
carbomonocycle,
hetero-acid)
benzenesulfonat
e (1:1).
P-21-0018.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triphenyl-,
(OECD Test heterocyclic
Guideline 111). compound-
carboxylate
(1:1).
P-21-0027.............. 01/23/2026 Hydrolysis as a (G)
Function of pH Heteropolycycli
(OECD Test c, Tri
Guideline 111). haloalkyl
carbomonocycle-
, hydroxy
carbomonocyclic
salt.
P-22-0055.............. 01/27/2026 Hydrolysis as a (G) Aromatic
Function of pH sulfonium
(OECD Test tricyclo
Guideline 111). fluoroalkyl
sulfonic acid
salt.
[[Page 34238]]
P-22-0129.............. 01/20/2026 Hydrolysis as a (G) Substituted
Function of pH heterocyclic
(OECD Test onium compound,
Guideline 111). salt with
heteropolysubst
itutedalkyl
substitutedtric
ycloalkane
carboxylate
(1:1), polymer
with 1-alkenyl-
4-[(alkyl
cycloalkyl)oxy]
carbomonocycle,
5-
ethyloctahydro-
4,7-methano-1H-
inden-5-yl 2-
methyl-2-
propenoate,
hexahydro-5-oxo-
2,6-
methanofuro[3,2-
b]furan-3-yl 2-
methyl-2-
propenoate and
4-hydroxyphenyl
2-methyl-2-
propenoate.
P-23-0037.............. 01/27/2026 Hydrolysis as a (G) Monoaromatic
Function of pH cyclic alkylene
(OECD Test sulfonium
Guideline 111). fluoroalkyl
sulfonic acid
salt.
P-23-0044.............. 01/27/2026 Hydrolysis as a (G) Monoaromatic
Function of pH cyclic alkylene
(OECD Test sulfonium
Guideline 111). fluoroalkyl
sulfonic acid
salt.
P-23-0050.............. 01/20/2026 Hydrolysis as a (G)
Function of pH Substitutedhete
(OECD Test rocyclic onium
Guideline 111). compound, salt
with
heteropolysubst
itutedalkyl
substitutedtric
ycloalkanecarbo
xylate (1:1),
polymer with 3-
ethenylphenol
and
heterosubstitut
edaromaticalkyl
2-methyl-2-
propenoate, di-
Me 2,2'-(1,2-
diazenediyl)
bis[2-
methylpropanoat
e]-initiated.
P-23-0080.............. 01/27/2026 Hydrolysis as a (G) Aromatic
Function of pH sulfonium
(OECD Test tricyclo
Guideline 111). fluoroalkyl
sulfonic acid
salt.
P-23-0093.............. 01/27/2026 Hydrolysis as a (G) Aromatic
Function of pH Dibenz
(OECD Test thiophenium
Guideline 111). fluoroalkyl
carbopolycycle
sulfonic acid
salt.
P-23-0136.............. 01/19/2026 Particle Size (G) Fatty acids,
Distribution reaction
Test Data; products with
Granulation hexamethylenedi
Test Data. amine and 12-
hydroxyoctadeca
noic acid.
P-23-0176.............. 01/23/2026 Hydrolysis as a (G) Sulfonium,
Function of pH bis (dihalo
(OECD Test carbomonocycle)
Guideline 111). carbomonocycle-
, salt with
dihalo-
sulfoalkyl
trisubstituted
benzoate.
P-23-0179.............. 01/23/2026 Hydrolysis as a (G) Sulfonium,
Function of pH bis (dihalo
(OECD Test carbomonocycle)
Guideline 111). carbomonocycle-
, salt with
substituted-
dihalobenzoate.
P-24-0042.............. 01/23/2026 Hydrolysis as a (G) Sulfonium,
Function of pH bis (dihalo
(OECD Test carbomonocycle)
Guideline 111). carbomonocycle-
, salt with
(dihalo-
sulfoalkyl)
(halo-
substituted
carbomonocycle)
carbopolycycle.
P-24-0160.............. 01/27/2026 Hydrolysis as a (G) Iodonium,
Function of pH bis (dialkyl
(OECD Test carbomonocycle)
Guideline 111). salt with alkyl
carbomonocycle
hetero acid.
P-24-0185.............. 01/20/2026 Hydrolysis as a (G) Sulfonium,
Function of pH triphenyl-,
(OECD Test salt with
Guideline 111). fluoro
sulfoalkyl-
fluoroalkyl
substituted-
heterotricycloa
lkane-
carboxylate
(1:1).
P-24-0190.............. 01/27/2026 Hydrolysis as a (G) Aromatic
Function of pH sulfonium
(OECD Test tricyclo salt
Guideline 111). with alkyl
carbomonocycle
hetero acid.
P-24-0195.............. 01/20/2026 Combined (G) Trimers of
Repeated Dose hexafluoroprope
Toxicity Study ne.
with the
Reproduction/
Developmental
Toxicity
Screening Test
(OECD Test
Guideline 422);
Partition
Coefficient (n-
Octanol/Water):
Shake Flask
Method (OECD
Test Guideline
107).
P-25-0016.............. 01/27/2026 Hydrolysis as a (G) Tri
Function of pH haloaromatic
(OECD Test iodonium
Guideline 111). dicyclo salt
with
polyhaloalkyl
carbomonocycle
hetero acid.
P-25-0028.............. 01/20/2026 Hydrolysis as a (G) Heteroonium,
Function of pH tri(substituted
(OECD Test aromatichydroca
Guideline 111). rbon)-, nitrate
(1:1).
P-25-0066.............. 01/22/2026 Water Solubility (G) Sulfonium,
(OECD Test bis (dihalo
Guideline 105); carbomonocycle)
Partition carbomonocycle-
Coefficient (n- , salt with
Octanol/Water): dihalo-
Shake Flask sulfoalkyl
Method (OECD [(alkenylcarbom
Test Guideline onocycle)substi
107); tuted]
Dissociation trisubstituted
Constants in benzoate,
Water (OECD polymer with
Test Guideline alkenylcarbomon
112). ocycle and
alkylcarbomonoc
ycle alkyl
alkenoate.
P-25-0067.............. 01/22/2026 Water Solubility (G) Sulfonium,
(OECD Test bis (dihalo
Guideline 105); carbomonocycle)
Partition carbomonocycle-
Coefficient (n- , salt with
Octanol/Water): trihalobenzoate
Shake Flask .
Method (OECD
Test Guideline
107);
Dissociation
Constants in
Water (OECD
Test Guideline
112).
P-25-0070.............. 01/22/2026 Water Solubility (G) Sulfonium,
(OECD Test bis (dihalo
Guideline 105); carbomonocycle)
Partition (halo
Coefficient (n- carbomonocycle)-
Octanol/Water): , salt with
Shake Flask dihalo-
Method (OECD sulfoalkyl
Test Guideline [(alkenylcarbom
107); onocycle)substi
Dissociation tuted]
Constants in trisubstituted
Water (OECD benzoate,
Test Guideline polymer with
112). alkenylcarbomon
ocycle and
alkylcarbomonoc
ycle alkyl
alkenoate.
P-25-0071.............. 01/22/2026 Water Solubility (G) Sulfonium,
(OECD Test bis (dihalo
Guideline 105); carbomonocycle)
Partition (halocarbomonoc
Coefficient (n- ycle)-, salt
Octanol/Water): with
Shake Flask trihalobenzoate
Method (OECD .
Test Guideline
107);
Dissociation
Constants in
Water (OECD
Test Guideline
112).
P-25-0097.............. 01/27/2026 Hydrolysis as a (G) Aromatic
Function of pH sulfonium
(OECD Test tricyclo salt
Guideline 111). with Carbopol
cycloalkyl
ester
polysubstituted
arylhetero-
acid.
[[Page 34239]]
P-25-0100.............. 01/27/2026 Hydrolysis as a (G) Aromatic
Function of pH sulfonium
(OECD Test tricyclo salt
Guideline 111). with alkyl
carbomonocycle
hetero acid.
P-25-0102.............. 01/27/2026 Hydrolysis as a (G)
Function of pH Darboheterocycl
(OECD Test ic aromatic
Guideline 111). sulfonium salt
with
dicycloalkyl
carbomonocycle
hetero acid.
P-25-0111.............. 01/27/2026 Hydrolysis as a (G) Haloaromatic
Function of pH iodonium
(OECD Test dicyclo salt
Guideline 111). with
polyfluoroalkyl
carbomonocycle
hetero acid.
P-25-0112.............. 01/27/2026 Hydrolysis as a (G) Haloaromatic
Function of pH iodonium
(OECD Test dicyclo salt
Guideline 111). with
halogenated
hydroxyaryl
carboxylic
acid.
P-25-0124.............. 01/27/2026 Hydrolysis as a (G) Alkyl
Function of pH aromatic
(OECD Test sulfonium,
Guideline 111). polycyclic
alkyl
sulfamate.
P-25-0135.............. 01/13/2026 Acute Inhalation (G) Metal- and
Toxicity (OECD metal- and
Test Guideline metal-doped
403). cobalt lithium
manganese
nickel oxide.
P-26-0010.............. 01/07/2026 Acute Toxicity (G)
Study. Ditridecylamine
, isomer
mixture.
------------------------------------------------------------------------
IV. Status Reports
Information about the TSCA section 5 PMNs, SNUNs, MCANs, and
exemption applications received, including the date of receipt, the
status of EPA's review, the final EPA determination, and the effective
date of EPA's determination, is available online at: <a href="https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices">https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices</a>.
Authority: 15 U.S.C. 2601 et seq.
Dated: June 1, 2026.
Mary Elissa Reaves,
Director, Office of Pollution Prevention and Toxics.
[FR Doc. 2026-11318 Filed 6-4-26; 8:45 am]
BILLING CODE 6560-50-P
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