Notice2026-03599

Proposed Data Collection Submitted for Public Comment and Recommendations

Primary source

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Published
February 24, 2026

Issuing agencies

Health and Human Services DepartmentCenters for Disease Control and Prevention

Abstract

The Centers for Disease Control and Prevention (CDC), as part of its continuing effort to reduce public burden and maximize the utility of government information, invites the general public and other Federal agencies the opportunity to comment on a continuing information collection, as required by the Paperwork Reduction Act of 1995. This notice invites comment on a proposed information collection project titled: National Wastewater Surveillance System for Infectious Diseases to Inform Public Health Action. Data is collected by jurisdictions and submitted to CDC for analysis and presentation for public awareness and health actions.

Full Text

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<title>Federal Register, Volume 91 Issue 36 (Tuesday, February 24, 2026)</title>
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[Federal Register Volume 91, Number 36 (Tuesday, February 24, 2026)]
[Notices]
[Pages 8884-8886]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2026-03599]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[60Day-26-1422; Docket No. CDC-2026-0266]


Proposed Data Collection Submitted for Public Comment and 
Recommendations

AGENCY: Centers for Disease Control and Prevention (CDC), Department of 
Health and Human Services (HHS).

ACTION: Notice with comment period.

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SUMMARY: The Centers for Disease Control and Prevention (CDC), as part 
of its continuing effort to reduce public burden and maximize the 
utility of government information, invites the general public and other 
Federal agencies the opportunity to comment on a continuing information 
collection, as required by the Paperwork Reduction Act of 1995. This 
notice invites comment on a proposed information collection project 
titled: National Wastewater Surveillance System for Infectious Diseases 
to Inform Public Health Action. Data is collected by jurisdictions and 
submitted to CDC for analysis and presentation for public awareness and 
health actions.

DATES: CDC must receive written comments on or before April 27, 2026.

ADDRESSES: You may submit comments, identified by Docket No. CDC-2026-
0266 by either of the following methods:
    <bullet> Federal eRulemaking Portal: <a href="http://www.regulations.gov">www.regulations.gov</a>. Follow 
the instructions for submitting comments.
    <bullet> Mail: Jeffrey M. Zirger, Information Collection Review 
Office, Centers for Disease Control and Prevention, 1600 Clifton Road 
NE, MS H21-8, Atlanta, Georgia 30329.
    Instructions: All submissions received must include the agency name 
and Docket Number. CDC will post, without change, all relevant comments 
to <a href="http://www.regulations.gov">www.regulations.gov</a>.

    Please note: Submit all comments through the Federal eRulemaking 
portal (<a href="http://www.regulations.gov">www.regulations.gov</a>) or by U.S. mail to the address listed 
above.


FOR FURTHER INFORMATION CONTACT: To request more information on the 
proposed project or to obtain a copy of the information collection plan 
and instruments, contact Jeffrey M. Zirger, Information Collection 
Review Office, Centers for Disease Control and Prevention, 1600 Clifton 
Road NE, MS H21-8, Atlanta, Georgia 30329; Telephone: 404-639-7570; 
Email: <a href="/cdn-cgi/l/email-protection#2f40424d6f4c4b4c01484059"><span class="__cf_email__" data-cfemail="3c53515e7c5f585f125b534a">[email&#160;protected]</span></a>.

SUPPLEMENTARY INFORMATION: Under the Paperwork Reduction Act of 1995 
(PRA) (44 U.S.C. 3501-3520), federal agencies must obtain approval from 
the Office of Management and Budget (OMB) for each collection of 
information they conduct or sponsor. In addition, the PRA also requires 
federal agencies to provide a 60-day notice in the Federal Register 
concerning each proposed collection of information, including each new 
proposed collection, each proposed extension of existing collection of 
information, and each reinstatement of previously approved information 
collection before submitting the

[[Page 8885]]

collection to the OMB for approval. To comply with this requirement, we 
are publishing this notice of a proposed data collection as described 
below.
    The OMB is particularly interested in comments that will help:
    1. Evaluate whether the proposed collection of information is 
necessary for the proper performance of the functions of the agency, 
including whether the information will have practical utility;
    2. Evaluate the accuracy of the agency's estimate of the burden of 
the proposed collection of information, including the validity of the 
methodology and assumptions used;
    3. Enhance the quality, utility, and clarity of the information to 
be collected;
    4. Minimize the burden of the collection of information on those 
who are to respond, including through the use of appropriate automated, 
electronic, mechanical, or other technological collection techniques or 
other forms of information technology, e.g., permitting electronic 
submissions of responses; and
    5. Assess information collection costs.

Proposed Project

    National Wastewater Surveillance System for Infectious Diseases to 
Inform Public Health Action (OMB Control No. 0920-1422, Exp. 12/31/
2026)--Revision--National Center for Emerging and Zoonotic Infectious 
Diseases (NCEZID), Centers for Disease Control and Prevention (CDC)

Background and Brief Description

    The National Wastewater Surveillance System (NWSS) was established 
in 2020 at CDC and continues to serve as a public health tool to 
provide wastewater surveillance for SARS-CoV-2. It has since expanded 
to include wastewater surveillance for emerging infectious diseases of 
public health concern such as Influenza, RSV, monkeypox virus, and 
measles, and is designed to permit the rapid addition or exchange of 
infectious disease targets for wastewater testing. This built-in 
flexibility will allow jurisdictions to adapt wastewater surveillance 
to changing public health needs, enable rapid responses to outbreaks or 
emergencies, and support broad capacity to detect future infectious 
disease threats.
    Wastewater surveillance provides aggregated, anonymized data at the 
community level to indicate RSV and influenza infection trends, measles 
prevalence, and data on other infectious disease targets. This data 
collection could also help inform jurisdictions early about outbreaks 
leading to efficient resource allocation, providing health departments 
with additional, independent surveillance data to assess community-
level infections.
    CDC requests OMB approval for an additional three years and for an 
estimated 453,505 annual burden hours. There are no costs to 
respondents other than their time to participate.

                                        Estimated Annualized Burden Hours
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                                                                                      Average
                                                       Number of      Number of      burden per   Annual burden
     Type of respondents             Form name        respondents   responses per     response        hours
                                                                      respondent     (in hours)
----------------------------------------------------------------------------------------------------------------
State, tribal, local,          Component 1 Forms:...           64  2,080..........       139/60  308,395.
 territorial health            <bullet> Attachment-
 departments.                   02_NWSS Data
                                Dictionary_v6.2.1_20
                                25-09-29_NEW.
                               <bullet> Attachment-
                                03_Wastewater_Master-
                                Reference-Guide_v4-2-
                                2.
                               <bullet> Attachment-
                                04_Component-
                                1_BioSample_ww_templ
                                ate_v1.9_NWSS.csv.
                               <bullet> Attachment-
                                05_SRA_ww_template_v
                                5.8_NWSS.csv.
                               <bullet> Attachment-
                                06_Component-
                                1_NCBI_DCIPHER_Cross
                                walk_DataDictionary.
                                csv_NEW.
                               <bullet> Attachment-
                                07_Component-1-
                                2_NWSS_DCIPHER_CSVBu
                                lkUploadTool_screens
                                hot.pdf.
                               <bullet> Attachment-
                                08_Component-
                                1_NWSS_1CDP_Wastewat
                                er_Data_CSV_Upload_T
                                emplate_v4_All
                                Fields_NEW.csv.
Private laboratory...........  Component 1 Forms:...            1  Up to 62,400          139/60  144,560.
                               <bullet> Attachment-                 (800 samples
                                02_Component-1_NWSS                 per week plus
                                Data                                400 sequenced
                                Dictionary_v5.0.0.                  samples per
                               <bullet> Attachment-                 week is 62,400
                                03 Component-                       annually).
                                1_CDC_seq_manifest_d
                                ata_dict.csv.
                               <bullet> Attachment-
                                04_Component-
                                1_BioSample_ww_templ
                                ate_v1.9_NWSS.csv.
                               <bullet> Attachment-
                                05_Component-
                                1_SRA_ww_template_v5
                                .7_NWSS.csv.
                               <bullet> Attachment-
                                06_Component-
                                1_NCBI_DCIPHER_Cross
                                walk_DataDictionary.
                                csv.
                               <bullet> Attachment-
                                07_Component-1-
                                2_NWSS_DCIPHER_CSVBu
                                lkUploadTool_screens
                                hot.pdf.
                               <bullet> Attachment-
                                08_Component-
                                1_NWSS_1CDP_Wastewat
                                er_Data_CSV_Upload_T
                                emplate_v4_All
                                Fields_NEW.csv.
                               <bullet> Attachment-
                                10_Component-
                                1_CDC_seq_manifest_d
                                ata_dict.xlsx.
State, tribal, local,          Component 2 Forms:...          213  1..............       155/60  550 (collection
 territorial health            <bullet> Sewershed                                                 only required
 departments and wastewater     spatial files, no                                                 once).
 utilities.                     form required..
                               <bullet> Attachment-
                                07_Component-1-
                                2_NWSS_DCIPHER_CSVBu
                                lkUploadTool_screens
                                hot.pdf.
                               <bullet> Attachment-
                                09_Component-
                                2_NWSS_DCIPHER_Sewer
                                shed_Name_Crosswalk_
                                CSV_Upload_Template_
                                NEW.
                                                     -----------------------------------------------------------
    Total....................  .....................  ...........  ...............  ...........  453,505.
----------------------------------------------------------------------------------------------------------------



[[Page 8886]]

Jeffrey M. Zirger,
Lead, Information Collection Review Office, Office of Scientific Public 
Health Ethics and Regulations, Office of Science, Centers for Disease 
Control and Prevention.
[FR Doc. 2026-03599 Filed 2-23-26; 8:45 am]
BILLING CODE 4163-18-P


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