Notice2025-23713

Proposed Collection; 60-Day Comment Request; the Clinical Trials Reporting Program (CTRP) Database (NCI)

Primary source

Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.

Published
December 23, 2025

Issuing agencies

Health and Human Services DepartmentNational Institutes of Health

Abstract

In compliance with the requirement of the Paperwork Reduction Act of 1995 to provide an opportunity for public comment on proposed data collection projects, the National Cancer Institute (NCI) will publish periodic summaries of proposed projects to be submitted to the Office of Management and Budget (OMB) for review and approval.

Full Text

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<title>Federal Register, Volume 90 Issue 244 (Tuesday, December 23, 2025)</title>
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[Federal Register Volume 90, Number 244 (Tuesday, December 23, 2025)]
[Notices]
[Pages 60112-60113]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-23713]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Proposed Collection; 60-Day Comment Request; the Clinical Trials 
Reporting Program (CTRP) Database (NCI)

AGENCY: National Institutes of Health, HHS.

ACTION: Notice.

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SUMMARY: In compliance with the requirement of the Paperwork Reduction 
Act of 1995 to provide an opportunity for public comment on proposed 
data collection projects, the National Cancer Institute (NCI) will 
publish periodic summaries of proposed projects to be submitted to the 
Office of Management and Budget (OMB) for review and approval.

DATES: Comments regarding this information collection are best assured 
of having their full effect if received within 60 days of the date of 
this publication.

FOR FURTHER INFORMATION CONTACT: To obtain a copy of the data 
collection plans and instruments, submit comments in writing, or 
request more information on the proposed project, contact Melissa Park, 
PRA Liaison, Office of Management Policy and Compliance, National 
Cancer Institute, 9609 Medical Center Drive, Room 2E196, Bethesda, MD 
20892 or call non-toll-free number (240) 276-5717 or email your 
request, including your address to: <a href="/cdn-cgi/l/email-protection#137e767f7a6060723d63726178537d7a7b3d747c65"><span class="__cf_email__" data-cfemail="c0ada5aca9b3b3a1eeb0a1b2ab80aea9a8eea7afb6">[email&#160;protected]</span></a>. Formal 
requests for additional plans and instruments must be requested in 
writing.

SUPPLEMENTARY INFORMATION: Section 3506(c)(2)(A) of the Paperwork 
Reduction Act of 1995 requires: written comments and/or suggestions 
from the public and affected agencies are invited to address one or 
more of the following points: (1) Whether the proposed collection of 
information is necessary for the proper performance of the function of 
the agency, including whether the information will have practical 
utility; (2) The accuracy of the agency's estimate of the burden of the 
proposed collection of information, including the validity of the 
methodology and assumptions used; (3) Ways to enhance the quality, 
utility, and clarity of the information to be collected; and (4) Ways 
to minimizes the burden of the collection of information on those who 
are to respond, including the use of appropriate automated, electronic, 
mechanical, or other technological collection techniques or other forms 
of information technology.
    Proposed Collection Title: The Clinical Trials Reporting Program 
(CTRP) Database, 0925-0600, Expiration Date 02/28/2026-REVISION, 
National Cancer Institute (NCI), National Institutes of Health (NIH).
    Need and Use of Information Collection: The Clinical Trials 
Reporting Program (CTRP) Database is an electronic resource that serves 
as a single, definitive source of information about all NCI-supported 
clinical research. This resource allows the NCI to consolidate 
reporting, aggregate information and reduce redundant submissions. 
Information is submitted by clinical research administrators as 
designees of clinical investigators who conduct NCI-supported clinical 
research. The designees can electronically access the CTRP website to 
complete the initial trial registration. Subsequent to registration, 
four amendments and four study subject accrual updates occur per trial 
annually.
    OMB approval is requested for 3 years. There are no costs to 
respondents other than their time. The estimated annualized burden 
hours are 18,000.

                                        Estimated Annualized Burden Hours
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                                                                     Number of     Average time
           Form name                 Type of         Number of     responses per   per response    Total annual
                                   respondents      respondents     respondent      (in hours)     burden hours
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Initial Registration..........  Individuals.....           3,000               1               1           3,000
Amendment.....................                             1,500               4               1           6,000
Update........................                             1,500               4               1           6,000
Accrual Updates...............                             3,000               4           15/60           3,000
                                                 ---------------------------------------------------------------
    Totals....................  ................           9,000          27,000  ..............          18,000
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[[Page 60113]]

    Dated: December 19, 2025.
Melissa Park,
Project Clearance Liaison, National Cancer Institute, National 
Institutes of Health.
[FR Doc. 2025-23713 Filed 12-22-25; 8:45 am]
BILLING CODE 4140-01-P


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Indexed from Federal Register on December 23, 2025.

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