Notice2025-22811
Pesticide Registration Review; Draft Human Health and/or Ecological Risk Assessment for Metrafenone; Notice of Availability
Primary source
Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.
Published
December 15, 2025
Issuing agencies
Environmental Protection Agency
Abstract
This notice announces the availability of EPA's draft human health and/or ecological risk assessments for the registration review of metrafenone. EPA is opening a 60-day public comment period for these risk assessments.
Full Text
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<title>Federal Register, Volume 90 Issue 238 (Monday, December 15, 2025)</title>
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[Federal Register Volume 90, Number 238 (Monday, December 15, 2025)]
[Notices]
[Pages 58001-58002]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-22811]
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ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-OPP-2017-0720; FRL-13056-01-OCSPP]
Pesticide Registration Review; Draft Human Health and/or
Ecological Risk Assessment for Metrafenone; Notice of Availability
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice.
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SUMMARY: This notice announces the availability of EPA's draft human
health and/or ecological risk assessments for the registration review
of metrafenone. EPA is opening a 60-day public comment period for these
risk assessments.
DATES: Comments must be received on or before February 13, 2026.
ADDRESSES: Submit your comments, to the docket identification (ID)
number for the specific pesticide of interest provided in Table 1 of
Unit I, by one of the following methods:
<bullet> Federal eRulemaking Portal: <a href="https://www.regulations.gov">https://www.regulations.gov</a>.
Follow the online instructions for submitting comments. Do not submit
electronically any information you consider to be Confidential Business
Information (CBI) or other information whose disclosure is restricted
by statute.
<bullet> Mail: <a href="https://www.epa.gov/dockets/where-send-comments-epa-dockets">https://www.epa.gov/dockets/where-send-comments-epa-dockets</a>. OPP Docket, Environmental Protection Agency Docket Center
(EPA/DC), (28221T), 1200 Pennsylvania Ave. NW, Washington, DC 20460-
0001.
FOR FURTHER INFORMATION CONTACT:
For pesticide specific information contact: The Chemical Review
Manager identified in Table 1 of Unit I.
For general questions on the registration review program, contact:
Melanie Biscoe, Pesticide Re-Evaluation Division (7508P), Office of
Pesticide Programs, Environmental Protection Agency, 1200 Pennsylvania
Ave. NW, Washington, DC 20460-0001; telephone number: (202) 566-0701;
email address: <a href="/cdn-cgi/l/email-protection#01636872626e642f6c646d606f6864416471602f666e77"><span class="__cf_email__" data-cfemail="70121903131f155e1d151c111e1915301500115e171f06">[email protected]</span></a>.
SUPPLEMENTARY INFORMATION:
I. Purpose of This Notice
Pursuant to 40 CFR 155.53(c), this notice announces the
availability of EPA's human health and/or ecological risk assessments
for metrafenone (Table 1) and opens a 60-day public comment period on
the risk assessments.
Table 1--Draft Risk Assessments Being Made Available for Public Comment
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Chemical review
Registration review case name manager and
and No. Docket ID No. contact
information
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Metrafenone Case 7052........... EPA-HQ-OPP-2020-00 Caleb Carr,
32. <a href="/cdn-cgi/l/email-protection#aecdcfdcdc80cdcfc2cbcceecbdecf80c9c1d8"><span class="__cf_email__" data-cfemail="04676576762a6765686166446174652a636b72">[email protected]</span></a>, (202) 566-
0636.
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II. Background
EPA is conducting its registration review of the chemical listed in
Table 1 of Unit I pursuant to the Federal Insecticide, Fungicide, and
Rodenticide Act (FIFRA) section 3(g) (7 U.S.C. 136(g)) and the
Procedural Regulations for Registration Review at 40 CFR part 155,
subpart C. FIFRA section 3(g) provides, among other things, that
pesticide registrations are to be reviewed every 15 years. Consistent
with 40 CFR 155.57, in its final registration review decision, EPA will
ultimately determine whether a pesticide continues to meet the
registration standard in FIFRA section 3(c)(5) (7 U.S.C. 136a(c)(5)).
As part of the registration review process, the Agency has
completed draft human health and/or ecological risk assessments for
metrafenone. Pursuant to 40 CFR 155.53(c), EPA generally provides for
at least a 30-day public comment period on draft human health and/or
ecological risk assessments during registration review. This comment
period is intended to provide an opportunity for public input on the
Agency's assessment of the human health and/or ecological risks posed
by use of these pesticides.
III. What should I consider as I prepare a comment for EPA?
A. Does this action apply to me?
This notice is directed to the public in general and may be of
interest to a wide range of stakeholders including environmental, human
health, farm worker, and agricultural advocates; the chemical industry;
pesticide users; and members of the public interested in the sale,
distribution, or use of pesticides. Since others also may be
interested, the Agency has not attempted to describe all the specific
entities that may be affected by this action. If you have any questions
regarding the applicability of this action to a particular entity,
consult the Chemical Review Manager identified in Table 1 in Unit I. In
submitting a comment to EPA, please consider the following:
1. Submitting CBI. Do not submit this information to EPA through
<a href="http://regulations.gov">regulations.gov</a> or email. Clearly mark the part or all of the
information that you claim to be CBI. For CBI information in a disk or
CD-ROM that you mail to EPA, mark the outside of the disk or CD-ROM as
CBI and then identify electronically within the disk or CD-ROM the
specific information that is claimed as CBI. In addition to one
complete version of the comment that includes information claimed as
CBI, a copy of the comment that does not contain the information
claimed as CBI must be submitted for inclusion in the public docket.
Information so marked will not be disclosed except in accordance with
procedures set forth in 40 CFR part 2.
2. Tips for preparing your comments. When preparing and submitting
your comments, see the commenting tips at <a href="https://www.epa.gov/dockets/commenting-epa-dockets">https://www.epa.gov/dockets/commenting-epa-dockets</a>.
3. Information submission requirements. Anyone may submit data or
information in response to this document. To be considered during a
pesticide's registration review, the submitted data or information must
meet the following requirements:
<bullet> To ensure that EPA will consider data or information
submitted, interested persons must submit the data or information
during the comment period. However, the Agency may, at its discretion,
consider data or information submitted at a later date.
<bullet> The data or information submitted must be presented in a
legible and useable form. For example, an English translation must
accompany any
[[Page 58002]]
material that is not in English, and a written transcript must
accompany any information submitted as an audio graphic or videographic
record. Written material may be submitted in paper or electronic form.
<bullet> Submitters must clearly identify the source of any
submitted data or information.
<bullet> Submitters may request the Agency to reconsider data or
information that the Agency rejected in a previous review. However,
submitters must explain why they believe the Agency should reconsider
the data or information in the pesticide's registration review.
All comments should be submitted using the methods in ADDRESSES and
must be received by the EPA on or before the closing date. The Agency
will consider all comments received during the public comment period
and make changes, as appropriate, to a draft human health and/or
ecological risk assessment. As appropriate, EPA may then issue a
revised risk assessment, explain any changes to the draft risk
assessment, and respond to comments.
Authority: 7 U.S.C. 136 et seq.
Dated: December 9, 2025.
Jean Anne Overstreet,
Director, Pesticide Re-Evaluation Division, Office of Pesticide
Programs.
[FR Doc. 2025-22811 Filed 12-12-25; 8:45 am]
BILLING CODE 6560-50-P
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