Notice2025-21674
Certain New Chemicals; Receipt and Status Information for July-August 2025
Primary source
Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.
Published
December 1, 2025
Issuing agencies
Environmental Protection Agency
Abstract
This document announces the Agency's receipt of new chemical submissions under the Toxic Substances Control Act (TSCA), including information about the receipt of a Premanufacture Notice (PMN), Significant New Use Notice (SNUN), Microbial Commercial Activity Notice (MCAN), and an amendment to a previously submitted notice; test information; a biotechnology exemption application; an application for a test marketing exemption (TME); and a notice of commencement of manufacture (defined by statute to include import) (NOC) for a new chemical substance. This document also provides a periodic status report on the new chemical substances that are currently under EPA review or have recently concluded review. EPA is hereby providing notice of receipt of this information, as required by TSCA, and an opportunity to comment. This document covers the period from 8/1/2025 to 8/31/2025.
Full Text
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<title>Federal Register, Volume 90 Issue 228 (Monday, December 1, 2025)</title>
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[Federal Register Volume 90, Number 228 (Monday, December 1, 2025)]
[Notices]
[Pages 55102-55107]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-21674]
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ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-OPPT-2025-0067; FRL-12475-08-OCSPP]
Certain New Chemicals; Receipt and Status Information for July-
August 2025
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of receipt and request for comment.
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SUMMARY: This document announces the Agency's receipt of new chemical
submissions under the Toxic Substances Control Act (TSCA), including
information about the receipt of a Premanufacture Notice (PMN),
Significant New Use Notice (SNUN), Microbial Commercial Activity Notice
(MCAN), and an amendment to a previously submitted notice; test
information; a biotechnology exemption application; an application for
a test marketing exemption (TME); and a notice of commencement of
manufacture (defined by statute to include import) (NOC) for a new
chemical substance. This document also provides a periodic status
report on the new chemical substances that are currently under EPA
review or have recently concluded review. EPA is hereby providing
notice of receipt of this information, as required by TSCA, and an
opportunity to comment. This document covers the period from 8/1/2025
to 8/31/2025.
DATES: Comments must be received on or before December 31, 2025.
ADDRESSES: Submit your comments, identified by docket identification
(ID) number EPA-HQ-OPPT-2025-0067 and the specific case number provided
in this document for the chemical substance related to your comment,
online at <a href="https://www.regulations.gov">https://www.regulations.gov</a>. Follow the online instructions
for submitting comments. Do not submit electronically any information
you consider to be Confidential Business Information (CBI) or other
information whose disclosure is restricted by statute. Additional
instructions on commenting and visiting the docket, along with more
information about dockets generally, is available at <a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>.
FOR FURTHER INFORMATION CONTACT:
For technical information: Jim Rahai, Project Management and
Operations Division (7407M), Office of Pollution Prevention and Toxics,
Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington,
DC 20460-0001; telephone number: (202) 564-8593; email address:
<a href="/cdn-cgi/l/email-protection#cbb9aaa3aaa2e5a1a2a68baebbaae5aca4bd"><span class="__cf_email__" data-cfemail="691b0801080047030004290c1908470e061f">[email protected]</span></a>.
For general information: The TSCA-Hotline, ABVI-Goodwill, 422 South
Clinton Ave. Rochester, NY 14620; telephone number: (202) 554-1404;
email address: <a href="/cdn-cgi/l/email-protection#3a6e69797b1772554e5653545f7a5f4a5b145d554c"><span class="__cf_email__" data-cfemail="86d2d5c5c7abcee9f2eaefe8e3c6e3f6e7a8e1e9f0">[email protected]</span></a>.
SUPPLEMENTARY INFORMATION:
[[Page 55103]]
I. Executive Summary
A. Does this action apply to me?
This action provides information that is directed to the public in
general.
B. What is the Agency's authority for taking this action?
EPA is publishing this document in the Federal Register as required
by sections 5 of the Toxic Substances Control Act (TSCA), 15 U.S.C.
2601 et seq., and corresponding EPA regulations.
Under TSCA, a chemical substance may be either an ``existing''
chemical substance or a ``new'' chemical substance, see <a href="https://www.epa.gov/chemicals-under-tsca">https://www.epa.gov/chemicals-under-tsca</a>. Any chemical substance that is not on
EPA's TSCA Inventory of Chemical Substances (TSCA Inventory) is
classified as a ``new chemical substance,'' while a chemical substance
that is listed on the TSCA Inventory is classified as an ``existing
chemical substance.'' See TSCA section 3(2) and (11). For more
information about the TSCA Inventory, see <a href="https://www.epa.gov/inventory">https://www.epa.gov/inventory</a>.
Any person who intends to manufacture (including import) a new
chemical substance for a non-exempt commercial purpose, or to
manufacture or process a chemical substance in a non-exempt manner for
a use that EPA has determined is a significant new use, is required by
TSCA section 5 to provide EPA with a PMN, MCAN, or SNUN, as
appropriate, before initiating the activity. EPA will review the
notice, make a risk determination on the new chemical substance or
significant new use, and take appropriate action as described in TSCA
section 5(a)(3).
TSCA section 5(h)(1) authorizes EPA to allow persons, upon
application and under appropriate restrictions, to manufacture a new
chemical substance, or manufacture or process a chemical substance
subject to a significant new use rule (SNUR) issued under TSCA section
5(a)(2), for ``test marketing'' purposes, upon a showing that the
manufacture, processing, distribution in commerce, use, and disposal of
the chemical substances will not present an unreasonable risk of injury
to health or the environment. This is referred to as a test marketing
exemption, or TME.
Premanufacture notification procedures for review of certain new
microbial products of biotechnology are established in 40 CFR part 725.
These pertain to MCANs and biotechnology exemptions, including TSCA
experimental release applications (TERAs), TMEs for microorganisms, and
Tier I and Tier II exemptions.
C. What action is the Agency taking?
This document provides notice of receipt and status reports for the
covered period and certain submissions under TSCA section 5 and
provides an opportunity to comment on this information. The Agency is
providing information about the receipt of PMNs, SNUNs, MCANs, and
amendments to a previously submitted notice; test information;
biotechnology exemption applications under 40 CFR part 725; TME
applications; NOCs for new chemical substances; and a periodic status
report on chemical substances that are currently under EPA review or
have recently concluded review.
D. What should I consider as I prepare my comments for EPA?
1. Submitting CBI. Do not submit CBI to EPA through <a href="https://www.regulations.gov">https://www.regulations.gov</a> or email. If you wish to include CBI in your
comment, please follow the instructions at <a href="https://www.epa.gov/dockets/commenting-epa-dockets#rules">https://www.epa.gov/dockets/commenting-epa-dockets#rules</a> and clearly mark the information that you
claim to be CBI. In addition to one complete version of the comment
that includes CBI, a copy of the comment without CBI must be submitted
for inclusion in the public docket. Information marked as CBI will not
be disclosed except in accordance with procedures set forth in 40 CFR
parts 2 and 703.
2. Tips for preparing your comments. When preparing and submitting
your comments, see the commenting tips at <a href="https://www.epa.gov/dockets/commenting-epa-dockets">https://www.epa.gov/dockets/commenting-epa-dockets</a>.
II. Background
A. What information is being provided in this document?
The tables in this document provide the following information on
the TSCA section 5 submissions received by EPA during this period and
determined to be complete consistent with 40 CFR 720.70(a).
<bullet> Case number. The EPA number assigned to the TSCA section 5
submissions. Please note that a case number may be listed more than
once in the table when the submission involves a subsequent amendment.
<bullet> Chemical substance. Name of the chemical substance, or
generic name if the specific name is claimed as CBI.
<bullet> Manufacturer. Name of the submitting manufacturer, to the
extent that such information is not subject to a CBI claim. The term
``manufacturer'' is defined by statute to include importer.
<bullet> Use(s). Potential uses identified by the manufacturer.
<bullet> Received. Date the submission was received by EPA.
<bullet> Commencement. Date of commencement provided by the
submitter in the NOC.
<bullet> Test information. For test information received, the type
of test information submitted to EPA based on the attachment type and
subtype data selected by the submitter.
B. What do the acronyms mean that are used in the tables?
As used in each of the tables, the following explanations apply:
<bullet> (S) indicates that the information in the table is the
specific information provided by the submitter.
<bullet> (G) indicates that the information in the table is generic
information because the specific information provided by the submitter
was claimed as CBI.
C. How can I access other information about TSCA section 5 submissions?
EPA provides information on its website about cases reviewed under
TSCA section 5, including the PMNs, SNUNs, MCANs, and exemption
applications received; the date of receipt; the final EPA determination
on the submission; and the effective date of EPA's determination. See
<a href="https://www.epa.gov/new-chemicals-under-toxic-substances-control-act-tsca/pre-manufacture-notices">https://www.epa.gov/new-chemicals-under-toxic-substances-control-act-tsca/pre-manufacture-notices</a>. In addition, information EPA receives
about chemical substances under TSCA, including non-CBI new chemical
submissions, can be accessed in ChemView at <a href="https://chemview.epa.gov/">https://chemview.epa.gov/</a> gov/.
III. Receipt Reports
Table 1 provides non-CBI information for the PMNs, SNUNs and MCANs
received by EPA that have passed an initial screening and determined to
be complete consistent with 40 CFR 720.70(a) during this period.
Table 1--PMN/SNUN/MCANs Received and Under Review
----------------------------------------------------------------------------------------------------------------
Received
Case No. date Manufacturer Use Chemical substance
----------------------------------------------------------------------------------------------------------------
J-25-0014.............. 08/12/2025 CBI............................ (G) Manufacture of (G) Modified Yeast,
an alcohol. with chromosomal
modifications to
improve
fermentation
characteristics.
[[Page 55104]]
J-25-0014A............. 08/27/2025 CBI............................ (G) Manufacture of (G) Modified Yeast,
an alcohol. with chromosomal
modifications to
improve
fermentation
characteristics.
P-23-0140.............. 08/01/2025 CBI............................ (G) Additive for (G) Polysaccharide,
consumer and (hydroxytrialkylam
commercial products. monio)alkyl ether,
chloride.
P-23-0162.............. 08/07/2025 CBI............................ (S) Transportation (G) Alkane
fuels, Chemical (glyceridic),
Feedstock, Fuel hydrotreated and
additive. isomerized.
P-24-0007.............. 08/14/2025 Kenrich Petrochemicals, Inc.... (S) Use as a (S) Titanium
dispersant for branched and
powders, as an linear C16-18 and
adhesion promoter C18-unsatd. fatty
in adhesives and acids iso-Pr alc.
sealants, all forms complexes.
KR PTOA, CAPOW KR
PTOA.
P-24-0093.............. 07/31/2025 Evonik Corporation............. (S) Surfactant in (G) Rhamnolipids,
laundry, and manual/ modified
hand dish pseudomonas-
detergent, in hard fermented, from
surface cleaner. dextrose, salts.
P-24-0094.............. 07/31/2025 Evonik Corporation............. (S) Surfactant in (G) Rhamnolipids,
laundry, and manual/ modified
hand dish pseudomonas-
detergent, in hard fermented, from
surface cleaner. dextrose, salts.
P-24-0095.............. 07/31/2025 Evonik Corporation............. (S) Surfactant in (G) Rhamnolipids,
laundry, and manual/ modified
hand dish pseudomonas-
detergent, in hard fermented, from
surface cleaner. dextrose, salts.
P-24-0096.............. 07/31/2025 Evonik Corporation............. (S) Surfactant in (G) Rhamnolipids,
laundry, and manual/ modified
hand dish pseudomonas-
detergent, in hard fermented, from
surface cleaner. dextrose, salts.
P-24-0116.............. 08/15/2025 CBI............................ (G) For use in (G) Phenol, 4,4-(1-
coatings for metal alkylidene) bis-,
parts. polymer with 2-
(chloromethyl)
oxirane, 4-
alkylphenyl ether,
reaction products
with
alkylpolyamine and
2-
(alkylamino)alkano
l, hydrolyzed,
alkanesulfonates
(salts).
P-24-0117.............. 08/15/2025 CBI............................ (G) For use in (G) Alkanoic acid,
coatings for metal compds. with
parts. hydrolyzed
bisphenol-
epichlorohydrin
polymer 4-
alkylphenyl ether-
alkylpolyamine and
2-
(alkylamino)alkano
l reaction
products.
P-24-0118.............. 08/15/2025 CBI............................ (G) For use in (G) Alkanoic acid,
coatings for metal compds. with
parts. [(aminoalkyl)imino
] bis[alkanol]-
bisphenol-
epichlorohydrin
polymer 4-
alkylphenyl ether-
2-
(alkylamino)alkano
l reaction
products.
P-24-0119.............. 08/15/2025 CBI............................ (G) For use in (G) Amidosulfonic
coatings for metal acid, compds. with
parts. [(aminoalkyl)imino
] bis[alkanol]-
bisphenol-
epichlorohydrin
polymer 4-
alkylphenyl ether-
2-
(alkylamino)alkano
l reaction
products.
P-24-0120.............. 08/15/2025 CBI............................ (G) For use in (G) Alkanoic acid,
coatings for metal compds. with
parts. hydrolyzed
bisphenol-
monoalkylamine-
epichlorohydrin
polymer 4-
alkylphenyl ether-
alkylpolyamine and
2-
(alkylamino)alkano
l reaction
products.
P-24-0121.............. 08/15/2025 CBI............................ (G) For use in (G) Phenol, 4,4-(1-
coatings for metal alkylidene) bis-,
parts. polymer with 2-
(chloromethyl)
oxirane and
monoalkanamine, 4-
alkylphenyl ether,
reaction products
with
alkylpolyamine and
2-
(alkylamino)alkano
l, hydrolyzed,
alkanesulfonates
(salts).
P-24-0155.............. 08/06/2025 CBI............................ (G) Raw material.... (G) Alkanoic acid,
[(alkylthio)substi
tutedalkyl] thio]-
,.
P-24-0173.............. 08/06/2025 CBI............................ (G) For making air (G) Rare earth
pollutant control doped zirconium
parts in oxide.
automobiles.
P-24-0174.............. 08/06/2025 CBI............................ (G) Making air (G) Rare earth
pollutants control doped zirconium
parts in oxide.
automobiles.
P-24-0175.............. 08/06/2025 CBI............................ (G) Air pollutants (G) Rare earth
control parts in doped zirconium
automobiles. oxide.
P-24-0176.............. 08/06/2025 CBI............................ (G) Making of air (G) Rare earth
pollutants control doped zirconium
parts in oxide.
automobiles.
P-24-0177.............. 08/06/2025 CBI............................ (G) Air pollutants (G) Rare earth
control parts in doped zirconium
automobiles. oxide.
P-24-0179.............. 08/06/2025 CBI............................ (G) Component in (G) Aluminum- and
batteries. metal-doped cobalt
metal nickel
oxide.
P-24-0180.............. 08/06/2025 CBI............................ (G) Component in (G) Aluminum- and
batteries. metal- and metal-
doped cobalt metal
nickel oxide.
P-24-0181.............. 08/06/2025 CBI............................ (G) Component in (G) Metal- and
batteries. metal-doped cobalt
metal metal nickel
oxide.
P-24-0182.............. 08/26/2025 CBI............................ (G) Chemical (G) Cobalt metal
precursor. nickel compound.
P-25-0005.............. 08/15/2025 CBI............................ (G) For use in (G) Cashew,
coatings for metal nutshell liq.,
parts. polymer with
[(aminoalkyl)imino
] bis[alkanol],
bisphenol and
epichlorohydrin,
reaction products
with
dialkanolamine,
alkylcarboxylates
(salts)
alkanesulfonates
(salts).
P-25-0006.............. 08/15/2025 CBI............................ (G) For use in (G) Phenol, 4,4-(1-
coatings for metal alkylidene) bis-,
parts. polymer with
[(aminoalkyl)imino
] bis[alkanol] and
2-(chloromethyl)
oxirane, 3-
alkyloxy-2-
hydroxypropyl
ethers, reaction
products with
dialkanolamine,
alkylcarboxylates
(salts)
alkanesulfonates
(salts).
P-25-0007.............. 08/15/2025 CBI............................ (G) For use in (G) Phenol, 4,4-(1-
coatings for metal alkylidene) bis-,
parts. polymer with
[(aminoalkyl)imino
] bis[alkanol] and
2-(chloromethyl)
oxirane, 4-
alkylphenyl
ethers, reaction
products with
dialkanolamine,
alkylcarboxylates
(salts)
alkanesulfonates
(salts).
P-25-0008.............. 08/15/2025 CBI............................ (G) For use in (G) Benzenediol,
coatings for metal polymer with
parts. [(aminoalkyl)imino
] bis[alkanol], 2-
(chloromethyl)oxir
ane and 4,4-(1-
alkylidene)
bis[phenol], 4-
alkylphenyl
ethers, reaction
products with
dialkanolamine,
alkylcarboxylates
(salts)
alkanesulfonates
(salts).
[[Page 55105]]
P-25-0009.............. 08/15/2025 CBI............................ (G) For use in (G) Cashew,
coatings for metal nutshell liq.,
parts. polymer with
[(aminoalkyl)imino
] bis[alkanol],
bisphenol,
epichlorohydrin
and benzenediol,
reaction products
with
dialkanolamine,
alkylcarboxylates
(salts)
alkanesulfonates
(salts).
P-25-0010.............. 08/15/2025 CBI............................ (G) For use in (G) Benzenediol,
coatings for metal polymer with
parts. [(aminoalkyl)imino
] bis[alkanol], 2-
(chloromethyl)oxir
ane and 4,4-(1-
alkylidene)
bis[phenol], 3-
alkyloxy-2-
hydroxypropyl
ethers, reaction
products with
dialkanolamine,
alkylcarboxylates
(salts)
alkanesulfonates
(salts).
P-25-0090.............. 08/19/2025 CBI............................ (G) Monomer for use (G) Carbamic acid,
in UV/EB technology. N,N'-
(trialkylalkanidyl
)bis-,
bis(propenyloxy)al
kyl ester.
P-25-0090.............. 08/20/2025 CBI............................ (G) Monomer for use (G) Carbamic acid,
in UV/EB technology. N,N'-
(trialkylalkanidyl
)bis-,
bis(propenyloxy)al
kyl ester.
P-25-0091.............. 08/19/2025 CBI............................ (G) Monomer for use (G) Carbamic acid,
in UV/EB technology. N,N'-
(trialkylalkanidyl
)bis-,
bis(propenyloxy)al
kyl ester.
P-25-0091.............. 08/20/2025 CBI............................ (G) Monomer for use (G) Carbamic acid,
in UV/EB technology. N,N'-
(trialkylalkanidyl
)bis-,
bis(propenyloxy)al
kyl ester.
P-25-0115.............. 08/18/2025 CBI............................ (G) Deposition (G) Silylamine.
material for use in
electronics
industry and non-
electronics
industry.
P-25-0123.............. 08/08/2025 CBI............................ (G) Ink component, (G) Butanamide,
Ingredient in ink. 2,2'-[(dihalo[1,1'-
biphenyl]-4,4'-
diyl) bis(2,1-
diazenediyl)]
bis[3-oxo, N,N'-
bis(substituted
heteropolycyclic
and alkyl
carbomonocyclic)
derivs.
P-25-0131.............. 08/06/2025 Osmo Labs, PBC................. (S) Non-Spray (G) Aryl ether
Personal Care aldehyde.
Products,
Categories include
fine fragrances,
shower gel,
shampoo, hair
styling products,
body lotion, face
cream, hand cream,
liquid foundation,
and nonspray
deodorant, laundry
(fabric softeners,
powdered and liquid
detergents, dryer
sheets, scent
boosters), surface
and general
household cleaning
(all-purpose
cleaners, cleaning
wipes, toilet bowl
cleaners, powdered
cleaners, floor
cleaners), air and
odor control
(liquid electrical
fresheners, gel air
fresheners, scented
candles, trash can
deodorizers, carpet
deodorizers), other
(scented draw
liners, pet product
deodorizers).
P-25-0132.............. 07/31/2025 CBI............................ (G) An ingredient (G) Alkenoic acid,
used in the alkyl-, alkyl-
manufacture of carbopolycyclic
photoresist. alkyl ester,
polymer with oxo-
(trihalo alkoxy)
alkyl alkyl
alkenoate and oxo-
[trihalo-
(trihaloalkyl)alko
xy] alkyl alkyl
alkenoate.
P-25-0133.............. 07/31/2025 CBI............................ (G) Component in (G) Fatty acids,
inks. dimers, polymers
with alkenoic acid
and polyol.
P-25-0134.............. 08/06/2025 Osmo Labs, PBC................. (S) Categories (G) Aryl alkynoic
include fine ethyl ester.
fragrances, shower
gel, shampoo, hair
styling products,
body lotion, face
cream, hand cream,
liquid foundation,
and non-spray
deodorant, laundry
(fabric softeners,
powdered and liquid
detergents, dryer
sheets, scent
boosters), surface
and general
household cleaning
(all-purpose
cleaners, cleaning
wipes, toilet bowl
cleaners, powdered
cleaners, floor
cleaners), air and
odor control
(liquid electrical
fresheners, gel air
fresheners, scented
candles, trash can
deodorizers, carpet
deodorizers), other
(scented draw
liners, pet product
deodorizers).
P-25-0135.............. 08/04/2025 CBI............................ (G) Used as a (G) Metal- and
component in metal- and metal-
battery doped cobalt
manufacturing. lithium manganese
nickel oxide.
P-25-0136.............. 08/04/2025 CBI............................ (G) Used as a (G) Metal- and
component in metal-doped cobalt
battery lithium manganese
manufacturing. nickel oxide.
P-25-0137.............. 08/06/2025 CBI............................ (G) Substance for (G) Cobalt lithium
the use in manganese nickel
manufacturing of oxide, metals.
battery components.
P-25-0138.............. 08/18/2025 CBI............................ (G) Polymer plastic. (G) Carbohydrates,
modified
microorganism-
fermented
Polyhydroxyalkanoa
te.
P-25-0139.............. 08/18/2025 CBI............................ (G) Polymer plastic. (G) Carbohydrates,
modified
microorganism-
fermented
Polyhydroxyalkanoa
te.
P-25-0140.............. 08/18/2025 CBI............................ (G) Polymer plastic. (G) Carbohydrates,
modified
microorganism-
fermented
Polyhydroxyalkanoa
te.
[[Page 55106]]
P-25-0141.............. 08/06/2025 Osmo Labs, PBC................. (S) Categories (G) Heteroaromatic
include fine alkyl ester.
fragrances, shower
gel, shampoo, hair
styling products,
body lotion, face
cream, hand cream,
liquid foundation,
and non-spray
deodorant, laundry
(fabric softeners,
powdered and liquid
detergents, dryer
sheets, scent
boosters), surface
and general
household cleaning
(all-purpose
cleaners, cleaning
wipes, toilet bowl
cleaners, powdered
cleaners, floor
cleaners), air and
odor control
(liquid electrical
fresheners, gel air
fresheners, scented
candles, trash can
deodorizers, carpet
deodorizers), other
(scented draw
liners, pet product
deodorizers).
P-25-0142.............. 08/21/2025 CBI............................ (G) Industrial (G) Propenoic acid,
intermediate. methyl-,
[bis[[dimethyl[[-
trimethyl-
bis[(trimethylsily
l)oxy]-
disiloxanyl]
ethyl] silyl] oxy]
-dimethyl-
[[trimethyl-
bis[(trimethylsily
l)oxy]-
disiloxaneyl]
ethyl]-
disiloxaneyl]
propyl ester.
P-25-0142.............. 08/27/2025 CBI............................ (G) Industrial (G) Propenoic acid,
intermediate. methyl-,
[bis[[dimethyl[[-
trimethyl-
bis[(trimethylsily
l)oxy]-
disiloxanyl]
ethyl] silyl] oxy]
-dimethyl-
[[trimethyl-
bis[(trimethylsily
l)oxy]-
disiloxaneyl]
ethyl]-
disiloxaneyl]
propyl ester.
SN-25-0005............. 08/18/2025 CBI............................ (G) Electronic (S) 2-Butene,
component 1,1,1,4,4,4-
manufacturing. hexafluoro-, (2Z)-
.
SN-25-0009............. 08/11/2025 Clariant Corporation........... (S) Selectivity (S) Heptane, 3,3-
improver for bis(methoxymethyl)-
catalysts used in 2,6-dimethyl-.
the production of
polyolefins.
----------------------------------------------------------------------------------------------------------------
Table 2 provides non-CBI information on the NOCs received by EPA
that have passed an initial screening during this period.
Table 2--NOCs Received and Under Review
----------------------------------------------------------------------------------------------------------------
Received Commencement
Case No. date date Chemical substance
----------------------------------------------------------------------------------------------------------------
P-14-0624................................. 08/14/2025 07/25/2025 (G) Cyclic amine, polymer with
haloalkyloxirane and. alpha. -hydro-.
omega. -hydroxypoly(oxy-1,2-
alkyldiyl), salt.
P-18-0150................................. 08/15/2025 08/06/2025 (S) Cyclohexanamine, N,N-dimethyl-,
compds. with 3-(cyclohexylamino)-1-
propanesulfonic acid-blocked 5-
isocyanato-1-(isocyanatomethyl)-1,3,3-
trimethylcyclohexane homopolymer.
P-18-0182................................. 08/14/2025 09/29/2024 (S) Multiwalled carbon nanotubes grown
perpendicularly on an aluminum foil
substrate using Fe catalyst.
P-21-0092................................. 08/08/2025 08/06/2025 (G) 2-Propenoic acid, (polyhydro-1,3-
dioxo-2H-isoindol-2-yl) alkyl ester.
P-22-0163................................. 08/14/2025 08/12/2025 (S) Multiwalled carbon nanotubes.
P-23-0037................................. 08/05/2025 07/17/2025 (G) Monoaromatic cyclic alkylene
sulfonium fluoroalkyl sulfonic acid
salt.
P-23-0093................................. 08/06/2025 07/20/2025 (G) Aromatic Dibenz thiophenium
fluoroalkyl carbopolycycle sulfonic
acid salt.
P-24-0110................................. 08/15/2025 07/23/2025 (G) Alkyl fatty acids, polymers with
substituted heteropolycyclic,
substituted carbomonocycle,
carbomonocyclic dicarboxylic acid and
trisubstituted alkyl, substituted
alkyl alkenoate-blocked, polymers with
substituted alkene, substituted bis
alkylalkanenitrile-initiated
heteromonocyclic alkenoate-substituted
alkanoic acid-alkyl alkenoate polymer
alkenoate, heteromonocyclic alkenoate,
substituted alkyl alkenoate, alkyl
alkenoate, alkyl alkenoate, alkenoic
acid and substituted carbomonocycle,
alkyl substituted alkyl alkanoate
initiated,- and substituted bis
alkylalkanenitrile-initiated.
P-25-0016................................. 08/06/2025 07/20/2025 (G) Trihaloaromatic iodonium dicyclo
salt with polyhaloalkyl carbomonocycle
hetero acid.
----------------------------------------------------------------------------------------------------------------
Table 3 provides non-CBI information on the test information that
has been received by EPA that have passed an initial screening during
this period.
Table 3--Test Information Received
------------------------------------------------------------------------
Received Type of test Chemical
Case No. date information Substance
------------------------------------------------------------------------
P-14-0712.............. 08/15/2025 Polychlorinated (S) Waste
Dibenzodioxins plastics,
and pyrolyzed, C5-
Polychlorinated 55 fraction.
Dibenzofurans
Testing.
P-18-0016.............. 07/29/2025 Partition (G) Aromatic
Coefficient (1- sulfonium
Octanol/Water): tricyclo
Slow-Stirring fluoroalkyl
Method (OECD sulfonic acid
Test Guideline salt.
123).
P-20-0042.............. 07/29/2025 Partition (G) Sulfonium,
Coefficient (1- trisaryl-, 7,7-
Octanol/Water): dialkyl-2-
Slow-Stirring heteropolycycli
Method (OECD c -1-
Test Guideline alkanesulfonate
123). (1:1).
[[Page 55107]]
P-21-0165.............. 08/12/2025 96-hr Fish (S)
Imbalance Test Glucopyranose,
using larvae of oligomeric,
the Eastern C1016alkyl
Rainbowfish glycosides,
Melanotaenia 3(3,4dicarboxy3
splendida (ESA hydroxy1oxobuto
SOP 117). xy)
2hydroxypropyl
ethers, sodium
salts.
P-22-0055.............. 07/29/2025 Partition (G) Aromatic
Coefficient (1- sulfonium
Octanol/Water): tricyclo
Slow-Stirring fluoroalkyl
Method (OECD sulfonic acid
Test Guideline salt.
123).
P-23-0037.............. 07/29/2025 Partition (G) Monoaromatic
Coefficient (1- cyclic alkylene
Octanol/Water): sulfonium
Slow-Stirring fluoroalkyl
Method (OECD sulfonic acid
Test Guideline salt.
123).
P-23-0044.............. 07/29/2025 Partition (G) Monoaromatic
Coefficient (1- cyclic alkylene
Octanol/Water): sulfonium
Slow-Stirring fluoroalkyl
Method (OECD sulfonic acid
Test Guideline salt.
123).
P-23-0080.............. 07/29/2025 Partition (G) Aromatic
Coefficient (1- sulfonium
Octanol/Water): tricyclo
Slow-Stirring fluoroalkyl
Method (OECD sulfonic acid
Test Guideline salt.
123).
P-23-0093.............. 07/29/2025 Partition (G) Aromatic
Coefficient (1- Dibenz
Octanol/Water): thiophenium
Slow-Stirring fluoroalkyl
Method (OECD carbopolycycle
Test Guideline sulfonic acid
123). salt.
P-24-0160.............. 07/29/2025 Partition (G) Iodonium,
Coefficient (1- bis (dialkyl
Octanol/Water): carbomonocycle)
Slow-Stirring salt with alkyl
Method (OECD carbomonocycle
Test Guideline hetero acid.
123).
P-24-0190.............. 07/29/2025 Partition (G) Aromatic
Coefficient (1- sulfonium
Octanol/Water): tricyclo salt
Slow-Stirring with alkyl
Method (OECD carbomonocycle
Test Guideline hetero acid.
123).
P-25-0016.............. 07/29/2025 Partition (G) Tri
Coefficient (1- haloaromatic
Octanol/Water): iodonium
Slow-Stirring dicyclo salt
Method (OECD with
Test Guideline polyhaloalkyl
123). carbomonocycle
hetero acid.
P-25-0097.............. 07/29/2025 Partition (G) Aromatic
Coefficient (1- sulfonium
Octanol/Water): tricyclo salt
Slow-Stirring with
Method (OECD dicycloalkyl
Test Guideline carbomonocycle
123). hetero acid.
P-25-0100.............. 07/29/2025 Partition (G) Aromatic
Coefficient (1- sulfonium
Octanol/Water): tricyclo salt
Slow-Stirring with alkyl
Method (OECD carbomonocycle
Test Guideline hetero acid.
123).
P-25-0102.............. 07/29/2025 Partition (G)
Coefficient (1- Carboheterocycl
Octanol/Water): ic aromatic
Slow-Stirring sulfonium salt
Method (OECD with
Test Guideline dicycloalkyl
123). carbomonocycle
hetero acid.
P-25-0111.............. 07/29/2025 Partition (G) Haloaromatic
Coefficient (1- iodonium
Octanol/Water): dicyclo salt
Slow-Stirring with
Method (OECD polyfluoroalkyl
Test Guideline carbomonocycle
123). hetero acid.
P-25-0112.............. 07/29/2025 Partition (G) Haloaromatic
Coefficient (1- iodonium
Octanol/Water): dicyclo salt
Slow-Stirring with
Method (OECD halogenated
Test Guideline hydroxyaryl
123). carboxylic
acid.
------------------------------------------------------------------------
IV. Status Reports
Information about the TSCA section 5 PMNs, SNUNs, MCANs, and
exemption applications received, including the date of receipt, the
status of EPA's review, the final EPA determination, and the effective
date of EPA's determination, is available online at: <a href="https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices">https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices</a>.
Authority: 15 U.S.C. 2601 et seq.
Dated: November 25, 2025.
Mary Elissa Reaves,
Director, Office of Pollution Prevention and Toxics.
[FR Doc. 2025-21674 Filed 11-28-25; 8:45 am]
BILLING CODE 6560-50-P
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