Rule2025-20460
Isocycloseram; Pesticide Tolerances
Primary source
Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.
Published
November 20, 2025
Effective
November 20, 2025
Issuing agencies
Environmental Protection Agency
Abstract
This regulation establishes tolerances for residues of isocycloseram (CASRN 2061933-85-3) in or on multiple commodities which are identified and discussed later in this document. Under the Federal Food, Drug, and Cosmetic Act (FFDCA), Syngenta Crop Protection, LLC submitted a petition to EPA requesting that EPA establish a maximum permissible level for residues of this pesticide in or on the identified commodities.
Full Text
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<title>Federal Register, Volume 90 Issue 222 (Thursday, November 20, 2025)</title>
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[Federal Register Volume 90, Number 222 (Thursday, November 20, 2025)]
[Rules and Regulations]
[Pages 52256-52263]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-20460]
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ENVIRONMENTAL PROTECTION AGENCY
40 CFR Part 180
[EPA-HQ-OPP-2021-0641; FRL-13015-01-OCSPP]
Isocycloseram; Pesticide Tolerances
AGENCY: Environmental Protection Agency (EPA).
[[Page 52257]]
ACTION: Final rule.
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SUMMARY: This regulation establishes tolerances for residues of
isocycloseram (CASRN 2061933-85-3) in or on multiple commodities which
are identified and discussed later in this document. Under the Federal
Food, Drug, and Cosmetic Act (FFDCA), Syngenta Crop Protection, LLC
submitted a petition to EPA requesting that EPA establish a maximum
permissible level for residues of this pesticide in or on the
identified commodities.
DATES: This regulation is effective November 20, 2025. Objections and
requests for hearings must be received on or before January 20, 2026
and must be filed in accordance with the instructions provided in 40
CFR part 178 (see also Unit I.C. of this document).
ADDRESSES: The docket for this action, identified by docket
identification (ID) number EPA-HQ-OPP-2021-0641, is available online at
<a href="https://www.regulations.gov">https://www.regulations.gov</a>. Additional information about dockets
generally, along with instructions for visiting the docket in person,
is available at <a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>.
FOR FURTHER INFORMATION CONTACT: Charles Smith, Director, Registration
Division (7505T), Office of Pesticide Programs, Environmental
Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-
0001; main telephone number: (202) 566-2427; email address:
<a href="/cdn-cgi/l/email-protection#04564042564a6b706d676177446174652a636b72"><span class="__cf_email__" data-cfemail="b7e5f3f1e5f9d8c3ded4d2c4f7d2c7d699d0d8c1">[email protected]</span></a>.
SUPPLEMENTARY INFORMATION:
I. Executive Summary
A. Does this action apply to me?
You may be potentially affected by this action if you are an
agricultural producer, food manufacturer, or pesticide manufacturer.
The following list of North American Industrial Classification System
(NAICS) codes is not intended to be exhaustive but rather provides a
guide to help readers determine whether this document applies to them.
Potentially affected entities may include:
<bullet> Crop production (NAICS code 111).
<bullet> Animal production (NAICS code 112).
<bullet> Food manufacturing (NAICS code 311).
<bullet> Pesticide manufacturing (NAICS code 32532).
B. What is EPA's authority for taking this action?
EPA is issuing this rulemaking under section 408 of the Federal
Food, Drug, and Cosmetic Act (FFDCA), 21 U.S.C. 346a. FFDCA section
408(b)(2)(A)(i) allows EPA to establish a tolerance (the legal limit
for a pesticide chemical residue in or on a food) only if EPA
determines that the tolerance is ``safe.'' FFDCA section
408(b)(2)(A)(ii) defines ``safe'' to mean that ``there is a reasonable
certainty that no harm will result from aggregate exposure to the
pesticide chemical residue, including all anticipated dietary exposures
and all other exposures for which there is reliable information.'' This
includes exposure through drinking water and in residential settings
but does not include occupational exposure. FFDCA section 408(b)(2)(C)
requires EPA to give special consideration to exposure of infants and
children to the pesticide chemical residue in establishing a tolerance
and to ``ensure that there is a reasonable certainty that no harm will
result to infants and children from aggregate exposure to the pesticide
chemical residue . . .''
C. How can I file an objection or hearing request?
Under FFDCA section 408(g), 21 U.S.C. 346a(g), any person may file
an objection to any aspect of this regulation and may also request a
hearing on those objections. If you fail to file an objection to the
final rule within the time period specified in the final rule, you will
have waived the right to raise any issues resolved in the final rule.
You must file your objection or request a hearing on this regulation in
accordance with the instructions provided in 40 CFR part 178. To ensure
proper receipt by EPA, you must identify the docket ID number EPA-HQ-
OPP-2021-0641 in the subject line on the first page of your submission.
All objections and requests for a hearing must be in writing and must
be received by the Hearing Clerk on or before January 20, 2026.
The EPA's Office of Administrative Law Judges (OALJ), in which the
Hearing Clerk is housed, urges parties to file and serve documents by
electronic means only, notwithstanding any other particular
requirements set forth in other procedural rules governing those
proceedings. See ``Revised Order Urging Electronic Filing and
Service,'' dated June 22, 2023, which can be found at <a href="https://www.epa.gov/system/files/documents/2023-06/2023-06-22%20-%20revised%20order%20urging%20electronic%20filing%20and%20service.pdf">https://www.epa.gov/system/files/documents/2023-06/2023-06-22%20-%20revised%20order%20urging%20electronic%20filing%20and%20service.pdf</a>.
Although the EPA's regulations require submission via U.S. Mail or hand
delivery, the EPA intends to treat submissions filed via electronic
means as properly filed submissions; therefore, the EPA believes the
preference for submission via electronic means will not be prejudicial.
When submitting documents to the OALJ electronically, a person should
utilize the OALJ e-filing system at <a href="https://yosemite.epa.gov/oa/eab/eab-alj_upload.nsf">https://yosemite.epa.gov/oa/eab/eab-alj_upload.nsf</a>.
In addition to filing an objection or hearing request with the
Hearing Clerk as described in 40 CFR part 178, please submit a copy of
the filing (excluding any Confidential Business Information (CBI)) for
inclusion in the public docket at <a href="https://www.regulations.gov">https://www.regulations.gov</a>. Follow
the online instructions for submitting comments. Do not submit
electronically any information you consider to be CBI or other
information whose disclosure is restricted by statute. If you wish to
include CBI in your request, please follow the applicable instructions
at <a href="https://www.epa.gov/dockets/commenting-epa-dockets#rules">https://www.epa.gov/dockets/commenting-epa-dockets#rules</a> and clearly
mark the information that you claim to be CBI. Information not marked
confidential pursuant to 40 CFR part 2 may be disclosed publicly by EPA
without prior notice.
II. Petitioned-For Tolerance
In the Federal Register of March 22, 2022 (87 FR 16133) (FRL-9410-
11-OCSPP), EPA issued a document pursuant to FFDCA section 408(d)(3),
21 U.S.C. 346a(d)(3), announcing the filing of a pesticide petition (PP
1F8934) by Syngenta Crop Protection, LLC, P.O. Box 18300, Greensboro,
NC 27419-8300. The petition requested that 40 CFR part 180 be amended
by establishing tolerances for residues of the insecticide
isocycloseram, in or on almond, hulls at 6 ppm; almond, oil at 1 ppm;
almond, roasted at 0.5 ppm; apple, wet pomace at 1 ppm; barley, grain
at 0.01 ppm; barley, hay at 0.01 ppm; barley, straw at 0.01 ppm;
buckwheat, grain at 0.01 ppm; buckwheat, forage at 0.01 ppm; buckwheat,
hay at 0.01 ppm; buckwheat, straw at 0.01 ppm; corn, field, grain at
0.01 ppm; corn, field, forage at 2 ppm; corn, field, stover at 1.5 ppm;
corn, pop, grain at 0.01 ppm; corn, pop, stover at 1.5 ppm; cotton, gin
byproducts at 10 ppm; cottonseed, subgroup 20C at 0.5 ppm; fruit,
citrus, group 10-10 at 0.4 ppm; fruit, pome, group 11-10 at 0.4 ppm;
fruit, stone, group 12-12 at 1 ppm; grain, cereal, forage, fodder and
straw, group 16 at 0.01 ppm; nut, tree, group 14-12 at 0.15 ppm; oat,
grain at 0.01 ppm; oat, forage at 0.01 ppm; oat, hay at 0.01 ppm; oat,
straw at 0.01 ppm; onion, bulb, subgroup 3-07A at 0.01 ppm; onion,
green, subgroup 3-07B at 0.9 ppm; orange, citrus oil at 190 ppm;
orange, dried pulp at 9 ppm; orange, peel at 5 ppm; orange, wet pulp at
3 ppm; peas and bean, dried shelled, except soybean,
[[Page 52258]]
subgroup 6C at 0.01 ppm; peanut, nutmeat at 0.01 ppm; pearl millet,
grain at 0.01 ppm; pearl millet, forage at 0.01 ppm; pearl millet, hay
at 0.01 ppm; pearl millet, straw at 0.01 ppm; peas, hay at 0.01 ppm;
peas, vine at 0.01 ppm; plum, prunes at 4 ppm; proso millet, grain at
0.01 ppm; proso millet, forage at 0.01 ppm; proso millet, hay at 0.01
ppm; proso millet, straw at 0.01 ppm; rapeseed, subgroup 20A at 0.01
ppm; rye, grain at 0.01 ppm; rye, forage at 0.01 ppm; rye, hay at 0.01
ppm; rye, straw at 0.01 ppm; soybean, seed at 0.15 ppm; soybean, hulls
at 0.5 ppm; teosinte, grain at 0.01 ppm; teosinte, forage at 0.01 ppm;
teosinte, hay at 0.01 ppm; teosinte, straw at 0.01 ppm; tomato, dried
pomace at 35 ppm; tomato, sun-dried at 3 ppm; tomato, wet pomace at 10
ppm; triticale, grain at 0.01 ppm; triticale, forage at 0.01 ppm;
triticale, straw at 0.01 ppm; vegetables, brassica, head and stem,
group 5-16 at 4 ppm; vegetables, cucurbit, group 9 at 0.1 ppm;
vegetables, fruiting, subgroup 8-10A at 0.5 ppm; vegetables, fruiting,
subgroup 8-10B at 0.6 ppm; vegetables, leafy, group 4-16 at 9 ppm;
vegetables, tuberous and corm, subgroup 1C at 0.01 ppm; wheat, grain at
0.01 ppm; wheat, forage at 0.01 ppm; wheat, hay at 0.01 ppm; wheat,
straw at 0.01 ppm; cattle, fat at 0.03 ppm; cattle, kidney at 0.03 ppm;
cattle, liver at 0.05 ppm; cattle, meat at 0.01 ppm; cattle, meat
byproducts at 0.05 ppm; milk at 0.01 ppm; milk, cream at 0.01 ppm;
goat, fat at 0.03 ppm; goat, kidney at 0.03 ppm; goat, liver at 0.05
ppm; goat, meat at 0.01 ppm; goat, meat byproducts at 0.05 ppm; horse,
fat at 0.03 ppm; horse, kidney at 0.03 ppm; horse, liver at 0.05 ppm;
horse, meat at 0.01 ppm; horse, meat byproducts at 0.05 ppm; sheep, fat
at 0.03 ppm; sheep, kidney at 0.03 ppm; sheep, liver at 0.05 ppm;
sheep, meat at 0.01 ppm; sheep, meat byproducts at 0.05 ppm; poultry
(muscle, fat, offal) at 0.01 ppm; birds' egg at 0.01 ppm. That document
referenced a summary of the petition prepared by Syngenta Crop
Protection, LLC, the in the docket, <a href="https://www.regulations.gov">https://www.regulations.gov</a>. No
substantive public comments were received in response to the notice of
filing.
Based upon review of the data supporting the petition, EPA has
modified the petitioned-for tolerance levels and commodity definitions
for several commodities. The reasons for these changes are explained in
Unit IV.C.
III. Final Tolerance Action
A. Aggregate Risk Assessment and Determination of Safety
Consistent with FFDCA section 408(b)(2)(D), and the factors
specified in FFDCA section 408(b)(2)(D), EPA has reviewed the available
scientific data and other relevant information in support of this
action. EPA has sufficient data to assess the hazards of and to make a
determination on aggregate exposure for isocycloseram including
exposure resulting from the tolerances established by this action.
EPA's assessment of exposures and risks associated with isocycloseram
is summarized in this unit.
B. Toxicological Profile
EPA has evaluated the available toxicity data and considered its
validity, completeness, and reliability as well as the relationship of
the results of the studies to human risk. EPA has also considered
available information concerning the variability of the sensitivities
of major identifiable subgroups of consumers, including infants and
children.
Isocycloseram is a new broad-spectrum insecticide. It belongs to
the isoxazolines chemical class, which have an insecticidal mode of
action based on allosteric modulation of the gamma aminobutyric acid
(GABA) receptor. The toxicology database for isocycloseram is adequate
for hazard characterization, toxicity endpoint selection, and Food
Quality Protection Act Safety Factor (FQPA SF) consideration for
registration in the U.S.
Rats are the most sensitive species in the database, and male rats
are more sensitive than female rats. The testes, epididymides, and
liver were the target organs of isocycloseram in oral toxicity studies
in rats. Tubular degeneration of testes, and cellular debris and
reduced sperm in the epididymides were observed in subchronic, chronic/
carcinogenicity, and one-generation reproduction studies in rats.
Additionally, hepatocyte vacuolation and/or inflammatory cell
infiltrate were noted in the chronic/carcinogenicity and one-generation
reproduction studies in rats. Toxicity in the rat was observed at lower
dose levels with increased duration of exposure. In the 28-day dermal
toxicity study in rats, no adverse effects were observed up to the
limit dose. No adverse effects were observed in mice following
subchronic and chronic exposure. Decreased body weight and poor
clinical conditions (vomiting and slight body tremors) were observed in
dogs after subchronic exposure.
There was no evidence of qualitative or quantitative life-stage
susceptibility in the rat and rabbit developmental toxicity studies
tested up to 15 mg/kg/day, and in one- and two-generation rat
reproduction studies tested up to 15 and 12 mg/kg/day respectively.
There was no evidence of neurotoxicity in the acute and subchronic
neurotoxicity studies up to the highest dose tested (1,000 mg/kg for
acute and 33 mg/kg/day for subchronic).
Isocycloseram is classified as ``Not Likely to be Carcinogenic to
Humans.'' No treatment-related increase in tumors was observed in the
carcinogenicity studies in rats and/or mice at doses that were
considered adequate to assess carcinogenicity. Additionally, there was
no evidence of mutagenicity in vivo or in vitro.
Isocycloseram and 26 metabolites/degradates were run through Derek
Nexus (v6.1.0), and many of the metabolites produced similar alerts to
the parent compound and expected to be equal or lesser mammalian
toxicity to the parent. EPA conservatively assumed comparable toxicity
for isocycloseram and relevant metabolites/degradates in the risk
assessment.
Specific information on the studies received and the nature of the
adverse effects caused by isocycloseram as well as the no-observed-
adverse-effect-level (NOAEL) and the lowest-observed-adverse-effect-
level (LOAEL) from the toxicity studies can be found at <a href="https://www.regulations.gov">https://www.regulations.gov</a> in document Isocycloseram. Human Health Risk
Assessment for the Section 3 Registration of the New Active Ingredient
Isocycloseram on Treated Seeds, Agricultural Field Crops, Indoor/
Outdoor Residential Areas, Residential/Commercial Turf, Greenhouse,
Commercial/Industrial Areas, Industrial Structures, and Agricultural
Structures (Isocycloseram Human Health Risk Assessment) can be found in
docket ID number EPA-HQ-OPP-2021-0641.
C. Toxicological Points of Departure/Levels of Concern
Once a pesticide's toxicological profile is determined, EPA
identifies toxicological points of departure (PODs) and levels of
concern to use in evaluating the risk posed by human exposure to the
pesticide. For hazards that have a threshold below which there is no
appreciable risk, the toxicological POD is used as the basis for
derivation of reference values for risk assessment. PODs are developed
based on a careful analysis of the doses in each toxicological study to
determine the dose at which no adverse effects are observed (the NOAEL)
and the lowest
[[Page 52259]]
dose at which adverse effects of concern are identified (the LOAEL).
Uncertainty/safety factors are used in conjunction with the POD to
calculate a safe exposure level--generally referred to as a population-
adjusted dose (PAD) or a reference dose (RfD)--and a safe margin of
exposure (MOE). For non-threshold risks, the Agency assumes that any
amount of exposure will lead to some degree of risk. Thus, the Agency
estimates risk in terms of the probability of an occurrence of the
adverse effect expected in a lifetime. For more information on the
general principles EPA uses in risk characterization and a complete
description of the risk assessment process visit <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/assessing-human-health-risk-pesticides">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/assessing-human-health-risk-pesticides</a>.
Acute and cancer dietary risk assessments are not required since no
appropriate toxicological effects attributable to a single exposure
(dose) and no treatment-related increase in tumors, respectively, were
observed in the available toxicity studies. The combined chronic
toxicity/carcinogenicity study in the rat was selected for the chronic
dietary endpoint for all populations with a NOAEL of 2 mg/kg/day. More
detailed information on the toxicological endpoints for isocycloseram
used for human risk assessment can be found in the Isocycloseram Human
Health Risk Assessment in docket ID number EPA-HQ-OPP-2021-0641.
D. Exposure Assessment
1. Dietary exposure from food and feed uses. In evaluating dietary
exposure to isocycloseram, EPA considered exposure under the
petitioned-for tolerances to be established in 40 CFR part 180. EPA
incorporated exposure from isocycloseram's residues of concern in food
and drinking water. EPA assessed dietary exposures from isocycloseram
in food as follows:
i. Acute exposure. Quantitative acute dietary exposure and risk
assessments are performed for a food-use pesticide, if a toxicological
study has indicated the possibility of an effect of concern occurring
as a result of a 1-day or single exposure. No such effects were
identified in the toxicological studies for isocycloseram; therefore, a
quantitative acute dietary exposure assessment is unnecessary.
ii. Chronic exposure. In conducting the chronic dietary exposure
assessment EPA used the Dietary Exposure Evaluation Model--Food
Commodity Intake Database (DEEM-FCID), Version 4.02, which incorporates
2005-2010 consumption data from United States Department of
Agriculture's (USDA's) National Health and Nutrition Examination
Survey/What We Eat in America (NHANES/WWEIA). As to residue levels in
food, EPA used tolerance-level residues (primary crops), calculated
residues (livestock), and 100% crop treated (PCT) assumptions.
iii. Cancer. Based on the data summarized in Unit III.A., EPA has
concluded that isocycloseram does not pose a cancer risk to humans.
Therefore, a dietary exposure assessment for the purpose of assessing
cancer risk is unnecessary.
iv. Anticipated residue and percent crop treated (PCT) information.
EPA did not use anticipated residue and/or PCT information in the
dietary assessment for isocycloseram. Tolerance-level residues for
primary crops, calculated residues for livestock and 100 PCT were
assumed for all food commodities.
2. Dietary exposure from drinking water. The Agency used screening
level water exposure models in the dietary exposure analysis and risk
assessment for isocycloseram in drinking water. These simulation models
take into account data on the physical, chemical, and fate/transport
characteristics of isocycloseram. Further information regarding EPA
drinking water models used in pesticide exposure assessment can be
found at <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/models-pesticide-risk-assessment">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/models-pesticide-risk-assessment</a>.
Based on the Pesticide Water Calculator (PWC Version 2.001), the
estimated drinking water concentrations (EDWCs) of isocycloseram for
chronic non-cancer assessments are estimated to be 9.9 ppb for surface
water and 0.48 ppb for ground water.
Modeled estimates of drinking water concentrations were directly
entered into the dietary exposure model. For chronic dietary risk
assessment, the water concentration of value of 9.9 ppb was used to
assess the contribution from drinking water.
3. From non-dietary exposure. The term ``residential exposure'' is
used in this document to refer to non-occupational, non-dietary
exposure (e.g., products registered for direct application to lawn and
for garden pest control, indoor pest control, termiticides, and flea
and tick control on pets). Isocycloseram is proposed for the following
uses that could result in residential exposures: lawns, indoor
environments, gardens, and trees. EPA assessed the following
residential exposure scenarios: Short term residential post-application
exposure in children 1 to less than 2 years old (1 to <2) from
incidental oral exposures resulting from indoor and lawns/turf
applications. Further information regarding EPA standard assumptions
and generic inputs for residential exposures may be found at <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedures-residential-pesticide">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedures-residential-pesticide</a>.
4. Cumulative effects from substances with a common mechanism of
toxicity. Section 408(b)(2)(D)(v) of FFDCA requires that, when
considering whether to establish, modify, or revoke a tolerance, the
Agency consider ``available information'' concerning the cumulative
effects of a particular pesticide's residues and ``other substances
that have a common mechanism of toxicity.''
Unlike other pesticides for which EPA has followed a cumulative
risk approach based on a common mechanism of toxicity, EPA has not made
a common mechanism of toxicity finding as to isocycloseram and any
other substances. For the purposes of this action, therefore, EPA has
not assumed that isocycloseram has a common mechanism of toxicity with
other substances. For information regarding EPA's efforts to determine
which chemicals have a common mechanism of toxicity and to evaluate the
cumulative effects of such chemicals, see EPA's website at <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/pesticide-cumulative-risk-assessment-framework">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/pesticide-cumulative-risk-assessment-framework</a>.
E. Safety Factor for Infants and Children
1. In general. FFDCA Section 408(b)(2)(C) provides that EPA shall
apply an additional tenfold (10X) margin of safety for infants and
children in the case of threshold effects to account for prenatal and
postnatal toxicity and the completeness of the database on toxicity and
exposure unless EPA determines based on reliable data that a different
margin of safety will be safe for infants and children. This additional
margin of safety is commonly referred to as the FQPA Safety Factor
(SF). In applying this provision, EPA either retains the default value
of 10X, or uses a different additional safety factor when reliable data
available to EPA support the choice of a different factor.
2. Prenatal and postnatal sensitivity. No evidence of qualitative
or quantitative life-stage susceptibility in the rat and rabbit
developmental toxicity studies and one- and two-generation rat
reproduction studies up to the highest doses tested.
[[Page 52260]]
3. Conclusion. EPA has determined that reliable data show the
safety of infants and children would be adequately protected if the
FQPA SF were reduced to 1X. That decision is based on the following
findings:
i. The toxicity database for isocycloseram is adequate for hazard
characterization, toxicity endpoint selection, and FQPA SF
consideration. EPA concluded that immunotoxicity and developmental
neurotoxicity (DNT) studies could be waived and that dosing in the
subchronic neurotoxicity (SCN) and rat and rabbit developmental
toxicity and two-generation reproduction toxicity studies is adequate
and additional studies are not required.
ii. There is no indication that isocycloseram is a neurotoxic
chemical and there is no need for a DNT study or additional uncertainty
factors (UFs) to account for neurotoxicity.
iii. There is no evidence that isocycloseram results in increased
quantitative or qualitative lifestage susceptibility in rats and
rabbits up to the highest dose tested. Although the rabbit and rat
definitive developmental studies did not test up to the limit dose and
there is a potential for susceptibility at higher doses, the concern is
low based on the weight-of-evidence (WOE) determination. The WOE
indicates an overall low level of concern for lifestage sensitivity
with no adverse effects observed in fetal compartments and that the
animals were adequately challenged in dosing for all lifestages, and
the selected PODs are protective of any potential effects that would be
observed at a higher dose.
iv. There are no residual uncertainties identified in the exposure
databases. The chronic dietary analysis incorporated 100 PCT and
tolerance-level residues for primary crops and calculated residues for
livestock and protective modeled water concentration estimates for
potential exposure through drinking water. Residential post-application
exposures are anticipated and were based on the 2012 Residential
Standard Operating Procedures (SOPs) and chemical-specific turf
transferrable residue (TTR) data. EPA does not believe that the non-
dietary occupational exposures are underestimated because they are also
based on conservative assumptions, including maximum application rates,
and protective standard values for unit exposures and acreage treated/
amount handled. Therefore, the dietary and residential exposure
assessments do not underestimate exposures.
F. Aggregate Risks and Determination of Safety
EPA determines whether acute and chronic dietary pesticide
exposures are safe by comparing aggregate exposure estimates to the
acute PAD (aPAD) and chronic PAD (cPAD). For linear cancer risks, EPA
calculates the lifetime probability of acquiring cancer given the
estimated aggregate exposure. Short-, intermediate-, and chronic-term
risks are evaluated by comparing the estimated aggregate food, water,
and residential exposure to the appropriate PODs to ensure that an
adequate MOE exists.
1. Acute risk. An acute aggregate risk assessment takes into
account acute exposure estimates from dietary consumption of food and
drinking water. No adverse effect resulting from a single oral exposure
was identified and no acute dietary endpoint was selected. Therefore,
isocycloseram is not expected to pose an acute risk.
2. Chronic risk. Using the exposure assumptions described in this
unit for chronic exposure, EPA has concluded that chronic exposure to
isocycloseram from food and water will utilize 67% of the cPAD for
children 1 to 2 years old, the population group receiving the greatest
exposure, and not of risk concern. Based on the explanation in Unit
III.C.3., regarding residential use patterns, chronic residential
exposure to residues of isocycloseram is not expected.
3. Short-term risk. Short-term aggregate exposure takes into
account short-term residential exposure plus chronic exposure to food
and water (considered to be a background exposure level).
Isocycloseram is currently registered for uses that could result in
short-term residential exposure, and the Agency has determined that it
is appropriate to aggregate chronic exposure through food and water
with short-term residential exposures to isocycloseram.
Using the exposure assumptions described in this unit for short-
term exposures, EPA has concluded the combined short-term food, water,
and residential exposures result in an aggregate MOE of 300 for food,
water, and residential exposure to children 1-2 years old. Because
EPA's level of concern for isocycloseram is an MOE below 100, these
MOEs are not of concern.
4. Intermediate-term risk. Intermediate-term aggregate exposure
takes into account intermediate-term residential exposure plus chronic
exposure to food and water (considered to be a background exposure
level). Because no intermediate-term residential exposure is expected,
an intermediate-term aggregate assessment was not conducted.
5. Aggregate cancer risk for U.S. population. Based on the lack of
any treatment-related increase in tumors in two adequate rodent
carcinogenicity studies, isocycloseram is not expected to pose a cancer
risk to humans.
6. Determination of safety. Based on these risk assessments, EPA
concludes that there is a reasonable certainty that no harm will result
to the general population, or to infants and children from aggregate
exposure to isocycloseram residues.
IV. Other Considerations
A. Analytical Enforcement Methodology
Adequate enforcement methodology (quick, easy, cheap, effective,
rugged, and safe (QuEChERS)-based high-performance liquid
chromatography with mass-spectrometric detection (HPLC-MS/MS) multi-
residue method (EN 15662:2009)) are available to enforce the tolerance
expression.
The method may be requested from: Chief, Analytical Chemistry
Branch, Environmental Science Center, 701 Mapes Rd., Ft. Meade, MD
20755-5350; telephone number: (410) 305-2905; email address:
<a href="/cdn-cgi/l/email-protection#661403150f0213030b03120e0902152603160748010910"><span class="__cf_email__" data-cfemail="493b2c3a202d3c2c242c3d21262d3a092c3928672e263f">[email protected]</span></a>.
B. International Residue Limits
In making its tolerance decisions, EPA seeks to harmonize U.S.
tolerances with international standards whenever possible, consistent
with U.S. food safety standards and agricultural practices. EPA
considers the international maximum residue limits (MRLs) established
by the Codex Alimentarius Commission (Codex), as required by FFDCA
section 408(b)(4). The Codex Alimentarius is a joint United Nations
Food and Agriculture Organization/World Health Organization food
standards program, and it is recognized as an international food safety
standards-setting organization in trade agreements to which the United
States is a party. EPA may establish a tolerance that is different from
a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain
the reasons for departing from the Codex level.
The Codex has established MRLs for residues of isocycloseram in or
on apple, wet pomace at 1 ppm; fruit, citrus, group 10-10, oil at 80
ppm; fruit, citrus, group 10-10, dried pulp at 3 ppm; and plum, prune,
dried at 1.5 ppm. These MRLs are the same level as the tolerances being
established for
[[Page 52261]]
residues of isocycloseram in the United States.
The Codex has also established MRLs for residues of isocycloseram
in or on cattle, meat at 0.02 ppm; goat, meat at 0.02 ppm; horse, meat
at 0.02 ppm; milk at 0.05 ppm; poultry, meat at 0.02 ppm and sheep,
meat at 0.02 ppm. These MRL levels are different than the tolerance
levels being established for isocycloseram in the United States. The
United Sates has established tolerances for each of the above-listed
commodities at 0.01 ppm to ensure no potential trade barriers with key
importing partners of U.S. meat (Korea) and milk (Mexico, Indonesia,
Vietnam) products.
C. Revisions to Petitioned-For Tolerances
The petitioner-requested commodity definitions for cattle, kidney;
cattle, liver (cattle, meat byproducts); goat, kidney; goat liver
(goat, meat byproducts); horse, kidney; horse, liver (horse, meat
byproducts); sheep, kidney; and sheep, liver (sheep, meat byproducts);
birds' eggs (egg); orange, citrus oil (fruit, citrus, group 10-10,
oil); orange, peel (fruit, citrus, group 10-10, dried pulp); cream
(milk, fat); pearl millet, forage (millet, pearl, forage); pearl
millet, grain (millet, pearl, grain); pearl millet, hay (millet, pearl,
hay); pearl millet, straw (millet, pearl, straw); proso millet, forage
(millet, proso, forage); proso millet, grain (millet, proso, grain);
proso millet, hay (millet, proso, hay); proso millet, straw (millet,
proso, straw); peanut, nutmeat (peanut); poultry (muscle, fat, offal)
(poultry, fat; poultry, meat; poultry, meat byproducts); plum, prunes
(plum, prune, dried); tomato, sun dried (tomato, dried); Vegetables,
Brassica, head and stem, group 5-16 (vegetable, brassica, head and
stem, group 5-16); vegetables, fruiting, subgroup 8-10A; pea, hay and
pea, vines (vegetable, legume, forage and hay, except soybean, subgroup
7-22A); vegetables, cucurbit, group 9 (vegetable, cucurbit, group 9);
vegetables, fruiting, subgroup 8-10A and vegetables, fruiting subgroup
8-10B (vegetable, fruiting, group 8-10); vegetables, leafy, group 4-16
(vegetable, leafy, group 4-16); peas and bean, dried shelled, except
soybean, subgroup 6C (vegetable, legume, pulse, bean, dried shelled,
except soybean, subgroup 6-22E and vegetable, legume, pulse, pea, dried
shelled, subgroup 6-22F); vegetables, tuberous and corm, subgroup 1C
(vegetable, tuberous and corm, subgroup 1C) are updated to Agency-
preferred vocabulary (in parentheses, above) for consistency across
chemicals.
Pursuant to 40 CFR 180.40(g), because there is a greater than 5x
difference in residues for the representative crops, pecan and almond,
the petitioner-requested tolerance for residues on nut, tree, group 14-
12, will not be established. Rather, EPA is establishing tolerances for
residues on individual nut commodities that are based on translation
from the available residue data on almond or pecan and their shared
taxonomic classification, plant morphology, growing season, and
agricultural practices. Using the residue data on almond, which shows
residues at 0.2 ppm, EPA is establishing tolerances at 0.2 ppm on
almond; almond, tropical; beechnut; bunya; candlenut; chestnut;
chinquapin; ginkgo; nut, pine; pequi; pine, brazilian; pistachio; and
yellowhorn. Using the residue data on pecan, which shows residues at
0.01 ppm, EPA is establishing tolerances at 0.01 ppm on African nut-
tree; bur oak; butternut; cashew; chestnut, guiana; coconut; hazelnut;
heartnut; monkey-pot; nut, brazil; nut, cajou;nut, coquito; nut, dika;
nut, hickory; nut, macadamia; nut, mongongo; nut, pachira; nut,
sapucaia; peanut; pecan; walnut, black; and walnut, English.
The petitioner-requested tolerance levels for cattle, fat; goat,
fat; horse, fat; and sheep, fat are modified from 0.03 ppm to 0.05 ppm
based on anticipated residues in ruminant commodities derived from the
Langmuir model. The petitioner-requested tolerance levels for cattle,
meat byproducts; goat, meat byproducts; horse, meat byproducts; and
sheep, meat byproducts are modified from 0.05 ppm to 0.02 ppm based on
the Langmuir model. The petitioner-requested tolerance levels were also
modified for fruit, citrus, group 10-10 from 0.4 ppm to 0.5 ppm;
vegetable, cucurbit, group 9 from 0.1 ppm to 0.15 ppm and for
vegetable, leafy, group 4-16 from 9 ppm to 10 ppm based on the
Organization for Economic Co-operation and Development (OECD) tolerance
calculator. The petitioner-requested tolerance levels were also
modified for tomato, dried from 3 ppm to 2 ppm; plum, prune, dried from
4 ppm to 1.5 ppm and fruit, citrus, group 10-10, oil from 190 ppm to 80
ppm to harmonize with Codex. Tolerances are established for grain,
aspirated fractions at 15 ppm and milk, fat at 0.3 ppm based on
calculated residues.
The petitioner-requested tolerances for residues on almond, oil;
almond, roasted; orange, peel; are not established since anticipated
residues are covered by the raw agricultural commodity or crop group
tolerances. The petitioner requested tolerances for residues on tomato,
dried pomace; and tomato, wet pomace, which are not significant
livestock feed items. These tolerances are not established since the
aforementioned commodities are not routinely traded on the commodities
exchange markets, and anticipated residues will not significantly
increase livestock dietary exposure.
Additionally, although the petition requested that EPA establish a
crop subgroup tolerance for rapeseed, subgroup 20A, after submission,
the petitioner requested that EPA establish a tolerance just for
rapeseed, seed at 0.01 ppm, instead of subgroup 20A. Accordingly, EPA
is establishing only the individual commodity tolerance at this time
because the label will be limited to the single crop, rather than
allowing use on all commodities in the subgroup. As a result, the
broader subgroup is unnecessary at this time.
V. Conclusion
Therefore, tolerances are established for residues of isocycloseram
in or on African nut-tree at 0.01 ppm; almond at 0.2 ppm; almond, hulls
at 6 ppm; almond, tropical at 0.2 ppm; apple, wet pomace at 1 ppm;
barley, grain at 0.01 ppm; barley, hay at 0.01 ppm; barley, straw at
0.01 ppm; beechnut at 0.2 ppm; buckwheat, forage at 0.01 ppm;
buckwheat, grain at 0.01 ppm; buckwheat, hay at 0.01 ppm; buckwheat,
straw at 0.01 ppm; bunya at 0.2 ppm; bur oak at 0.01 ppm; butternut at
0.01 ppm; candlenut at 0.2 ppm; cashew at 0.01 ppm; cattle, fat at 0.05
ppm; cattle, meat at 0.01 ppm; cattle, meat byproducts at 0.02 ppm;
chestnut at 0.2 ppm; chestnut, guiana at 0.01 ppm; chinquapin at 0.2
ppm; coconut at 0.01 ppm; corn, field, forage at 2 ppm; corn, field,
grain at 0.01 ppm; corn, field, stover at 1.5 ppm; corn, pop, grain at
0.01 ppm; corn, pop, stover at 1.5 ppm; cotton, gin byproducts at 10
ppm; cottonseed, subgroup 20C at 0.5 ppm; egg at 0.01 ppm; fruit,
citrus, group 10-10 at 0.5 ppm; fruit, citrus, group 10-10, dried pulp
at 3 ppm; fruit, citrus, group 10-10, oil at 80 ppm; fruit, pome, group
11-10 at 0.4 ppm; fruit, stone, group 12-12 at 1 ppm; ginkgo at 0.2
ppm; goat, fat at 0.05 ppm; goat, meat at 0.01 ppm; goat, meat
byproducts at 0.02 ppm; grain, aspirated fractions at 15 ppm; hazelnut
at 0.01 ppm; heartnut at 0.01; horse, fat at 0.05 ppm; horse, meat at
0.01 ppm; horse, meat byproducts at 0.02 ppm; horse-chestnut, Japanese
at 0.01 ppm; milk at 0.01 ppm; milk, fat at 0.3 ppm; millet, pearl,
forage at 0.01 ppm; millet, pearl, grain at 0.01 ppm; millet, pearl,
hay at 0.01 ppm; millet, pearl, straw at 0.01 ppm; millet, proso,
forage at 0.01 ppm; millet, proso,
[[Page 52262]]
grain at 0.01 ppm; millet, proso, hay at 0.01 ppm; millet, proso, straw
at 0.01 ppm; monkey-pot at 0.01 ppm; nut, brazil at 0.01 ppm; nut,
cajou at 0.01 ppm; nut, coquito at 0.01 ppm; nut, dika at 0.01 ppm;
nut, hickory at 0.01 ppm; nut, macadamia at 0.01 ppm; nut, mongongo at
0.01 ppm; nut, monkey puzzle at 0.2 ppm; nut, okari at 0.2 ppm; nut,
pachira at 0.01 ppm; nut, peach palm at 0.2 ppm; nut, pili at 0.2 ppm;
nut, pine at 0.2 ppm; nut, sapucaia at 0.01 ppm; oat, forage at 0.01
ppm; oat, grain at 0.01 ppm; oat, hay at 0.01 ppm; oat, straw at 0.01
ppm; onion, bulb, subgroup 3-07A at 0.01 ppm; onion, green, subgroup 3-
07B at 0.9 ppm; peanut at 0.01 ppm; pecan at 0.01 ppm; pequi at 0.2
ppm; pine, brazilian at 0.2 ppm; pistachio at 0.2 ppm; plum, prune,
dried at 1.5 ppm; poultry, fat at 0.01 ppm; poultry, meat at 0.01 ppm;
poultry, meat byproducts at 0.01 ppm; rapeseed, seed at 0.01 ppm; rye,
forage at 0.01 ppm; rye, grain at 0.01 ppm; rye, hay at 0.01 ppm; rye,
straw at 0.01 ppm; sheep, fat at 0.05 ppm; sheep, meat at 0.01 ppm;
sheep, meat byproducts at 0.02 ppm; soybean, hulls at 0.5 ppm; soybean,
seed at 0.15 ppm; teosinte, forage at 0.01 ppm; teosinte, grain at 0.01
ppm; teosinte, hay at 0.01 ppm; teosinte, straw at 0.01 ppm; tomato,
dried at 2 ppm; triticale, forage at 0.01 ppm; triticale, grain at 0.01
ppm; triticale, straw at 0.01 ppm; vegetables, brassica, head and stem,
group 5-16 at 4 ppm; vegetable, cucurbit, group 9 at 0.15 ppm;
vegetable, foliage of legume, except soybean subgroup 7-22A at 0.01
ppm; vegetable, fruiting, group 8-10 at 0.6 ppm; vegetable, leafy,
group 4-16 at 10 ppm; vegetable, legume, pulse, bean, dried shelled,
except soybean, subgroup 6-22E at 0.01 ppm; vegetable, legume, pulse,
pea, dried shelled, subgroup 6-22F at 0.01 ppm; vegetable, tuberous and
corm, subgroup 1C at 0.01 ppm; walnut, black at 0.01 ppm; walnut,
English at 0.01 ppm, wheat, forage at 0.01 ppm; wheat, grain at 0.01
ppm; wheat, hay at 0.01 ppm; wheat, straw at 0.01 ppm; and yellowhorn
at 0.2 ppm.
VI. Statutory and Executive Order Reviews
Additional information about these statutes and Executive Orders
can be found at <a href="https://www.epa.gov/laws-regulations/laws-and-executive-orders">https://www.epa.gov/laws-regulations/laws-and-executive-orders</a>.
A. Executive Order 12866: Regulatory Planning and Review
This action is exempt from review under Executive Order 12866 (58
FR 51735, October 4, 1993), because it establishes or modifies a
pesticide tolerance or a tolerance exemption under FFDCA section 408 in
response to a petition submitted to the Agency. The Office of
Management and Budget (OMB) has exempted these types of actions from
review under Executive Order 12866.
B. Executive Order 14192: Unleashing Prosperity Through Deregulation
Executive Order 14192 (90 FR 9065, February 6, 2025) does not apply
because actions that establish a tolerance under FFDCA section 408 are
exempted from review under Executive Order 12866.
C. Paperwork Reduction Act (PRA)
This action does not impose an information collection burden under
the PRA 44 U.S.C. 3501 et seq., because it does not contain any
information collection activities.
D. Regulatory Flexibility Act (RFA)
Since tolerance actions that are established on the basis of a
petition under FFDCA section 408(d), such as the tolerance in this
final rule, do not require the issuance of a proposed rule, the
requirements of the RFA, 5 U.S.C. 601 et seq., do not apply to this
action.
E. Unfunded Mandates Reform Act (UMRA)
This action does not contain an unfunded mandate of $100 million or
more (in 1995 dollars and adjusted annually for inflation) as described
in UMRA, 2 U.S.C. 1531-1538, and does not significantly or uniquely
affect small governments. The action imposes no enforceable duty on any
State, local, or Tribal governments or on the private sector.
F. Executive Order 13132: Federalism
This action does not have federalism implications as specified in
Executive Order 13132 (64 FR 43255, August 10, 1999), because it will
not have substantial direct effects on the states, on the relationship
between the National Government and the States, or on the distribution
of power and responsibilities among the various levels of government.
G. Executive Order 13175: Consultation and Coordination With Indian
Tribal Governments
This action does not have Tribal implications as specified in
Executive Order 13175 (65 FR 67249, November 9, 2000), because it will
not have substantial direct effects on Tribal governments, on the
relationship between the Federal Government and the Indian Tribes, or
on the distribution of power and responsibilities between the Federal
Government and Indian Tribes.
H. Executive Order 13045: Protection of Children From Environmental
Health Risks and Safety Risks
This action is not subject to Executive Order 13045 (62 FR 19885,
April 23, 1997) because tolerance actions like this one are exempt from
review under Executive Order 12866. However, EPA's 2021 Policy on
Children's Health applies to this action. This rule finalizes tolerance
actions under the FFDCA, which requires EPA to give special
consideration to exposure of infants and children to the pesticide
chemical residue in establishing a tolerance and to ``ensure that there
is a reasonable certainty that no harm will result to infants and
children from aggregate exposure to the pesticide chemical residue . .
.'' (FFDCA 408(b)(2)(C)). The Agency's consideration is summarized in
Unit III.E.
I. Executive Order 13211: Actions Concerning Regulations That
Significantly Affect Energy Supply, Distribution or Use
This action is not subject to Executive Order 13211 (66 FR 28355)
(May 22, 2001) because it is not a significant regulatory action under
Executive Order 12866.
J. National Technology Transfer Advancement Act (NTTAA)
This action does not involve technical standards that would require
Agency consideration under NTTAA section 12(d), 15 U.S.C. 272.
K. Congressional Review Act (CRA)
This action is subject to the CRA, 5 U.S.C. 801 et seq., and EPA
will submit a rule report to each House of the Congress and to the
Comptroller General of the United States. This action is not a ``major
rule'' as defined by 5 U.S.C. 804(2).
List of Subjects in 40 CFR Part 180
Environmental protection, Administrative practice and procedure,
Agricultural commodities, Pesticides and pests, Reporting and
recordkeeping requirements.
Dated: November 18, 2025.
Edward Messina,
Director, Office of Pesticide Programs.
For the reasons set forth in the preamble, 40 CFR chapter I is
amended as follows:
[[Page 52263]]
PART 180--TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES
IN FOOD
0
1. The authority citation for part 180 continues to read as follows:
Authority: 21 U.S.C. 321(q), 346a and 371.
0
2. Add Sec. 180.730 to subpart C to read as follows:
Sec. 180.730 Isocycloseram; tolerances for residues.
(a) General. (1) Tolerances are established for residues of the
insecticide isocycloseram, including its metabolites and degradates, in
or on the commodities in the table below. Compliance with the tolerance
levels specified below is to be determined by measuring only
isocycloseram, 4-[5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-
4,5-dihydro-1,2-oxazol-3-yl]-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-
methylbenzamide, in or on the following commodities:
Table 1 to Paragraph (a)
------------------------------------------------------------------------
Parts per
Commodity million
------------------------------------------------------------------------
African nut-tree............................................. 0.01
Almond....................................................... 0.2
Almond, hulls................................................ 6
Almond, tropical............................................. 0.2
Apple, wet pomace............................................ 1
Barley, grain................................................ 0.01
Barley, hay.................................................. 0.01
Barley, straw................................................ 0.01
Beechnut..................................................... 0.2
Buckwheat, forage............................................ 0.01
Buckwheat, grain............................................. 0.01
Buckwheat, hay............................................... 0.01
Buckwheat, straw............................................. 0.01
Bunya........................................................ 0.2
Bur oak...................................................... 0.01
Butternut.................................................... 0.01
Candlenut.................................................... 0.2
Cashew....................................................... 0.01
Cattle, fat.................................................. 0.05
Cattle, meat................................................. 0.01
Cattle, meat byproducts...................................... 0.02
Chestnut..................................................... 0.2
Chestnut, guiana............................................. 0.01
Chinquapin................................................... 0.2
Coconut...................................................... 0.01
Corn, field, forage.......................................... 2
Corn, field, grain........................................... 0.01
Corn, field, stover.......................................... 1.5
Corn, pop, grain............................................. 0.01
Corn, pop, stover............................................ 1.5
Cotton, gin byproducts....................................... 10
Cottonseed subgroup 20C...................................... 0.5
Egg.......................................................... 0.01
Fruit, citrus, group 10-10................................... 0.5
Fruit, citrus, group 10-10, dried pulp....................... 3
Fruit, citrus, group 10-10, oil.............................. 80
Fruit, pome, group 11-10..................................... 0.4
Fruit, stone, group 12-12.................................... 1
Ginkgo....................................................... 0.2
Goat, fat.................................................... 0.05
Goat, meat................................................... 0.01
Goat, meat byproducts........................................ 0.02
Grain, aspirated fractions................................... 15
Hazelnut..................................................... 0.01
Heartnut..................................................... 0.01
Horse, fat................................................... 0.05
Horse, meat.................................................. 0.01
Horse, meat byproducts....................................... 0.02
Horse-chestnut, japanese..................................... 0.01
Milk......................................................... 0.01
Milk, fat.................................................... 0.3
Millet, pearl, forage........................................ 0.01
Millet, pearl, grain......................................... 0.01
Millet, pearl, hay........................................... 0.01
Millet, pearl, straw......................................... 0.01
Millet, proso, forage........................................ 0.01
Millet, proso, grain......................................... 0.01
Millet, proso, hay........................................... 0.01
Millet, proso, straw......................................... 0.01
Monkey-pot................................................... 0.01
Nut, brazil.................................................. 0.01
Nut, cajou................................................... 0.01
Nut, coquito................................................. 0.01
Nut, dika.................................................... 0.01
Nut, hickory................................................. 0.01
Nut, macadamia............................................... 0.01
Nut, mongongo................................................ 0.01
Nut, monkey puzzle........................................... 0.2
Nut, okari................................................... 0.2
Nut, pachira................................................. 0.01
Nut, peach palm.............................................. 0.2
Nut, pili.................................................... 0.2
Nut, pine.................................................... 0.2
Nut, sapucaia................................................ 0.01
Oat, forage.................................................. 0.01
Oat, grain................................................... 0.01
Oat, hay..................................................... 0.01
Oat, straw................................................... 0.01
Onion, bulb, subgroup 3-07A.................................. 0.01
Onion, green, subgroup 3-07B................................. 0.9
Peanut....................................................... 0.01
Pecan........................................................ 0.01
Pequi........................................................ 0.2
Pine, brazilian.............................................. 0.2
Pistachio.................................................... 0.2
Plum, prune, dried........................................... 1.5
Poultry, fat................................................. 0.01
Poultry, meat................................................ 0.01
Poultry, meat byproducts..................................... 0.01
Rapeseed, seed............................................... 0.01
Rye, forage.................................................. 0.01
Rye, grain................................................... 0.01
Rye, hay..................................................... 0.01
Rye, straw................................................... 0.01
Sheep, fat................................................... 0.05
Sheep, meat.................................................. 0.01
Sheep, meat byproducts....................................... 0.02
Soybean, hulls............................................... 0.5
Soybean, seed................................................ 0.15
Teosinte, forage............................................. 0.01
Teosinte, grain.............................................. 0.01
Teosinte, hay................................................ 0.01
Teosinte, straw.............................................. 0.01
Tomato, dried................................................ 2
Triticale, forage............................................ 0.01
Triticale, grain............................................. 0.01
Triticale, straw............................................. 0.01
Vegetable, brassica, head and stem, group 5-16............... 4
Vegetable, cucurbit, group 9................................. 0.15
Vegetable, foliage of legume, except soybean, subgroup 7-22A. 0.01
Vegetable, fruiting, group 8-10.............................. 0.6
Vegetable, leafy, group 4-16................................. 10
Vegetable, legume, pulse, bean, dried shelled, except 0.01
soybean, subgroup 6-22E.....................................
Vegetable, legume, pulse, pea, dried shelled, subgroup 6-22F. 0.01
Vegetable, tuberous and corm, subgroup 1C.................... 0.01
Walnut, black................................................ 0.01
Walnut, english.............................................. 0.01
Wheat, forage................................................ 0.01
Wheat, grain................................................. 0.01
Wheat, hay................................................... 0.01
Wheat, straw................................................. 0.01
Yellowhorn................................................... 0.2
------------------------------------------------------------------------
(b) [Reserved]
[FR Doc. 2025-20460 Filed 11-19-25; 8:45 am]
BILLING CODE 6560-50-P
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