Notice2025-18186

Agency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Tobacco Health Document Submission

Primary source

Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.

Published
September 19, 2025

Issuing agencies

Health and Human Services DepartmentFood and Drug Administration

Abstract

The Food and Drug Administration (FDA) is announcing that a proposed collection of information has been submitted to the Office of Management and Budget (OMB) for review and clearance under the Paperwork Reduction Act of 1995.

Full Text

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<title>Federal Register, Volume 90 Issue 180 (Friday, September 19, 2025)</title>
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[Federal Register Volume 90, Number 180 (Friday, September 19, 2025)]
[Notices]
[Pages 45218-45220]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-18186]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Food and Drug Administration

[Docket No. FDA-2025-N-0351]


Agency Information Collection Activities; Submission for Office 
of Management and Budget Review; Comment Request; Tobacco Health 
Document Submission

AGENCY: Food and Drug Administration, HHS.

ACTION: Notice.

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SUMMARY: The Food and Drug Administration (FDA) is announcing that a 
proposed collection of information has been submitted to the Office of 
Management and Budget (OMB) for review and clearance under the 
Paperwork Reduction Act of 1995.

DATES: Submit written comments (including recommendations) on the 
collection of information by October 20, 2025.

ADDRESSES: To ensure that comments on the information collection are 
received, OMB recommends that written comments be submitted to <a href="https://www.reginfo.gov/public/do/PRAMain">https://www.reginfo.gov/public/do/PRAMain</a>. Find this particular information 
collection by selecting ``Currently under Review--Open for Public 
Comments'' or by using the search function. The OMB control number for 
this information collection is 0910-0654. Also include the FDA docket 
number found in brackets in the heading of this document.

FOR FURTHER INFORMATION CONTACT: Amber Sanford, Office of Operations, 
Food and Drug Administration, Three White Flint North, 10A-12M, 11601 
Landsdown St., North Bethesda, MD 20852, 301-796-8867, 
<a href="/cdn-cgi/l/email-protection#603032213314010606200604014e0808134e070f16"><span class="__cf_email__" data-cfemail="08585a495b7c696e6e486e6c692660607b266f677e">[email&#160;protected]</span></a>.

SUPPLEMENTARY INFORMATION: In compliance with 44 U.S.C. 3507, FDA has 
submitted the following proposed collection of information to OMB for 
review and clearance.

[[Page 45219]]

Tobacco Health Document Submission

OMB Control Number 0910-0654--Revision

    This information collection supports FDA guidance. The Federal 
Food, Drug, and Cosmetic Act (FD&C Act) authorizes FDA to regulate the 
manufacture, marketing, and distribution of tobacco products to protect 
the public health generally and to reduce tobacco use by minors.
    Section 904(a)(4) of the FD&C Act ((21 U.S.C. 387d(a)(4)) requires 
each tobacco product manufacturer or importer, or agent thereof, to 
submit all documents developed after June 22, 2009, ``that relate to 
health, toxicological, behavioral, or physiologic effects of current or 
future tobacco products, their constituents (including smoke 
constituents), ingredients, components, and additives'' (herein 
referred to as ``tobacco health documents'' or ``health documents'').
    The guidance document ``Health Document Submission Requirements for 
Tobacco Products (Revised)'' (2023) (<a href="http://www.fda.gov/regulatory-information/search-fda-guidance-documents/tobacco-health-document-submission">www.fda.gov/regulatory-information/search-fda-guidance-documents/tobacco-health-document-submission</a>) requests tobacco health document submissions from 
manufacturers and importers of tobacco products based on statutory 
requirements and compliance dates.\1\ We updated the guidance to 
reflect revised references to current FDA websites, which we will 
publish upon OMB approval. As indicated in the guidance, all 
manufacturers and importers of tobacco products are now subject to the 
FD&C Act and are required to comply with section 904(a)(4), which 
requires immediate and ongoing submission of health documents developed 
after June 22, 2009 (the date of enactment of the Family Smoking 
Prevention and Tobacco Control Act (Pub. L. 111-31)). However, FDA 
generally does not intend to enforce the requirement at this time with 
respect to all such health documents, so long as a specified set of 
documents, those developed between June 23, 2009, and December 31, 
2009, are provided at least 90 days prior to the delivery for 
introduction of tobacco products into interstate commerce. Thereafter, 
manufacturers should preserve all health documents, including those 
that relate to products for further manufacturing and those developed 
after December 31, 2009, for future submission to FDA. All Agency 
guidance documents are issued in accordance with our good guidance 
practice regulations in 21 CFR 10.115, which provide for public comment 
at any time.
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    \1\ FDA announced the availability of a guidance on this 
collection in the Federal Register on April 20, 2010 (75 FR 20606) 
[revised December 5, 2016 (81 FR 87565), August 10, 2017 (82 FR 
37459), and March 20, 2023 (88 FR 16636)].
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    FDA has been collecting the information submitted pursuant to 
section 904(a)(4) of the FD&C Act through a facilitative electronic 
form and through a paper form (Form FDA 3743) for those individuals who 
choose not to use the electronic method. You may access the electronic 
and paper forms on our website, at <a href="http://www.fda.gov/tobacco-products/manufacturing/submit-documents-ctp-portal">www.fda.gov/tobacco-products/manufacturing/submit-documents-ctp-portal</a> and <a href="http://www.fda.gov/media/78652/download">www.fda.gov/media/78652/download</a>, respectively. In addition to the electronic and paper forms, 
FDA issued the guidance on this collection to assist persons making 
tobacco health document submissions. For further assistance, FDA has 
provided a technical guide, embedded hints, and a web tutorial on the 
electronic portal via <a href="http://www.fda.gov/media/78631/download?attachment">www.fda.gov/media/78631/download?attachment</a>, 
<a href="http://www.fda.gov/tobacco-products/manufacturing/submit-documents-ctp-portal#what%20can">www.fda.gov/tobacco-products/manufacturing/submit-documents-ctp-portal#what%20can</a>, and <a href="http://www.fda.gov/industry/fda-esubmitter/using-esubmitter-prepare-tobacco-product-submissions">www.fda.gov/industry/fda-esubmitter/using-esubmitter-prepare-tobacco-product-submissions</a>.
    In this information collection, FDA is proposing to continue its 
compliance plan and request all manufacturers and importers of tobacco 
products, if not previously submitted, at least 90 days prior to the 
delivery for introduction into interstate commerce. Thereafter, 
manufacturers should preserve all health documents, including those 
that relate to products for further manufacturing and those developed 
after December 31, 2009, for future submission to FDA.
    In the Federal Register of June 27, 2025 (90 FR 27640), FDA 
published a 60-day notice requesting public comment on the proposed 
collection of information. Although one comment was received, it was 
not responsive to the four collection of information topics solicited.
    FDA estimates the burden of this collection of information as 
follows:

                                                       Table 1--Estimated Annual Reporting Burden
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                                                                                         Number of
                              Activity                                  Number of      responses per     Total annual    Average burden    Total hours
                                                                       respondents       respondent       responses       per response
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Tobacco Health Document Submissions and Form FDA 3743..............              10              3.2               32               50            1,600
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\1\ There are no capital costs or operating and maintenance costs associated with this collection of information.

    Since the publication of the 60-day Federal Register notice, FDA 
discovered that we erroneously omitted the discussion of the removal of 
a line item from the burden chart. As such, FDA estimates that a 
tobacco health document submission as required by section 904(a)(4) of 
the FD&C Act, will take approximately 50 hours per submission based on 
FDA experience. To derive the number of respondents for this provision, 
FDA assumes that very few manufacturers or importers, or agents 
thereof, would have health documents to submit. We anticipate 32 
document submissions will be submitted on an annual basis by 10 
respondents for an average of 3.2 submissions per respondent. We 
anticipate that manufacturers without additional documents have already 
completed their notification through a single FDA Form 3743 submission. 
Conversely, our experience shows that manufacturers with additional 
documents generally make multiple submissions. FDA estimates the annual 
reporting burden for these manufacturers to be 1,600 hours.
    FDA has adjusted its burden estimate by removing estimates of 
burden associated with tobacco health document submissions for NTN 
products because the compliance period for initial submission from NTN 
manufacturers has passed. This has resulted in a decrease of 200 hours 
and 100 respondents. With this revision, all tobacco product 
manufacturers are now accounted for under the single tobacco health 
document submissions

[[Page 45220]]

information collection activity listed in Table 1.

Grace R. Graham,
Deputy Commissioner for Policy, Legislation, and International Affairs.
[FR Doc. 2025-18186 Filed 9-18-25; 8:45 am]
BILLING CODE 4164-01-P


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Indexed from Federal Register on September 19, 2025.

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