Notice2025-18131

Foreign-Trade Zone (FTZ) 189, Notification of Proposed Production Activity; Grand River Aseptic Manufacturing; (Pharmaceutical Products); Caledonia and Grand Rapids, Michigan

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Published
September 19, 2025

Issuing agencies

Commerce DepartmentForeign-Trade Zones Board

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<title>Federal Register, Volume 90 Issue 180 (Friday, September 19, 2025)</title>
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[Federal Register Volume 90, Number 180 (Friday, September 19, 2025)]
[Notices]
[Page 45172]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-18131]


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Federal Register / Vol. 90, No. 180 / Friday, September 19, 2025 / 
Notices

[[Page 45172]]



DEPARTMENT OF COMMERCE

Foreign-Trade Zones Board

[B-44-2025]


Foreign-Trade Zone (FTZ) 189, Notification of Proposed Production 
Activity; Grand River Aseptic Manufacturing; (Pharmaceutical Products); 
Caledonia and Grand Rapids, Michigan

    Kent-Ottawa-Muskegon Foreign-Trade Zone Authority, grantee of FTZ 
189, submitted a notification of proposed production activity to the 
FTZ Board (the Board) on behalf of Grand River Aseptic Manufacturing 
(GRAM) for GRAM's facilities in Caledonia and Grand Rapids within 
Subzone 189H. The notification conforming to the requirements of the 
Board's regulations (15 CFR 400.22) was received on September 12, 2025.
    Pursuant to 15 CFR 400.14(b), FTZ production activity would be 
limited to the specific foreign-status material(s)/component(s) and 
specific finished product(s) described in the submitted notification 
(summarized below) and subsequently authorized by the Board. The 
benefits that may stem from conducting production activity under FTZ 
procedures are explained in the background section of the Board's 
website--accessible via <a href="http://www.trade.gov/ftz">www.trade.gov/ftz</a>.
    The proposed finished products are atigotatug--nivolumab 420mg and 
360mg/vials (70mg and 60mg/mL) and atigotatug--nivolumab 560mg and 
480mg/vials (70mg and 60mg/mL) (duty-free).
    The proposed foreign-status material is nivolumab (180mg/mL) active 
pharmaceutical ingredient (duty-free).
    Public comment is invited from interested parties. Submissions 
shall be addressed to the Board's Executive Secretary and sent to: 
<a href="/cdn-cgi/l/email-protection#99ffede3d9edebf8fdfcb7fef6ef"><span class="__cf_email__" data-cfemail="086e7c72487c7a696c6d266f677e">[email&#160;protected]</span></a>. The closing period for their receipt is October 27, 
2025.
    A copy of the notification will be available for public inspection 
in the ``Online FTZ Information System'' section of the Board's 
website.
    For further information, contact Christopher Wedderburn at 
<a href="/cdn-cgi/l/email-protection#bffcd7cdd6cc91e8dadbdbdacdddcacdd1ffcbcddedbda91d8d0c9"><span class="__cf_email__" data-cfemail="094a617b607a275e6c6d6d6c7b6b7c7b67497d7b686d6c276e667f">[email&#160;protected]</span></a>.

    Dated: September 15, 2025.
Elizabeth Whiteman,
Executive Secretary.
[FR Doc. 2025-18131 Filed 9-18-25; 8:45 am]
BILLING CODE 3510-DS-P


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Indexed from Federal Register on September 19, 2025.

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