Notice2025-17563

Certain New Chemicals; Receipt and Status Information for July 2025

Primary source

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Published
September 11, 2025

Issuing agencies

Environmental Protection Agency

Abstract

This document announces the Agency's receipt of new chemical submissions under the Toxic Substances Control Act (TSCA), including information about the receipt of a Premanufacture Notice (PMN), Significant New Use Notice (SNUN), Microbial Commercial Activity Notice (MCAN), and an amendment to a previously submitted notice; test information; a biotechnology exemption application; an application for a test marketing exemption (TME); and a notice of commencement of manufacture (defined by statute to include import) (NOC) for a new chemical substance. This document also provides a periodic status report on the new chemical substances that are currently under EPA review or have recently concluded review. EPA is hereby providing notice of receipt of this information, as required by TSCA, and an opportunity to comment. This document covers the period from 7/1/2025 to 7/31/2025.

Full Text

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<title>Federal Register, Volume 90 Issue 174 (Thursday, September 11, 2025)</title>
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[Federal Register Volume 90, Number 174 (Thursday, September 11, 2025)]
[Notices]
[Pages 44062-44068]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-17563]


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ENVIRONMENTAL PROTECTION AGENCY

[EPA-HQ-OPPT-2025-0067; FRL-12475-07-OCSPP]


Certain New Chemicals; Receipt and Status Information for July 
2025

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of receipt and request for comment.

-----------------------------------------------------------------------

SUMMARY: This document announces the Agency's receipt of new chemical 
submissions under the Toxic Substances Control Act (TSCA), including 
information about the receipt of a Premanufacture Notice (PMN), 
Significant New Use Notice (SNUN), Microbial Commercial Activity Notice 
(MCAN), and an amendment to a previously submitted notice; test 
information; a biotechnology exemption application; an application for 
a test marketing exemption (TME); and a notice of commencement of 
manufacture (defined by statute to include import) (NOC) for a new 
chemical substance. This document also provides a periodic status 
report on the new chemical substances that are currently under EPA 
review or have recently concluded review. EPA is hereby providing 
notice of receipt of this information, as required by TSCA, and an 
opportunity to comment. This document covers the period from 7/1/2025 
to 7/31/2025.

DATES: Comments must be received on or before October 14, 2025.

ADDRESSES: Submit your comments, identified by docket identification 
(ID) number EPA-HQ-OPPT-2025-0067 and the specific case number provided 
in this document for the chemical substance related to your comment, 
online at <a href="https://www.regulations.gov">https://www.regulations.gov</a>. Follow the online instructions 
for submitting comments. Do not submit electronically any information 
you consider to be Confidential Business Information (CBI) or other 
information whose disclosure is restricted by statute. Additional 
instructions on commenting and visiting the docket, along with more 
information about dockets generally, is

[[Page 44063]]

available at <a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>.

FOR FURTHER INFORMATION CONTACT: 
    For technical information: Jim Rahai, Project Management and 
Operations Division (7407M), Office of Pollution Prevention and Toxics, 
Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, 
DC 20460-0001; telephone number: (202) 564-8593; email address: 
<a href="/cdn-cgi/l/email-protection#0775666f666e296d6e6a4762776629606871"><span class="__cf_email__" data-cfemail="3042515851591e5a595d705540511e575f46">[email&#160;protected]</span></a>.
    For general information: The TSCA-Hotline, ABVI-Goodwill, 422 South 
Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404; 
email address: <a href="/cdn-cgi/l/email-protection#c490978785e98cabb0a8adaaa184a1b4a5eaa3abb2"><span class="__cf_email__" data-cfemail="baeee9f9fb97f2d5ced6d3d4dffadfcadb94ddd5cc">[email&#160;protected]</span></a>.

SUPPLEMENTARY INFORMATION:

I. Executive Summary

A. Does this action apply to me?

    This action provides information that is directed to the public in 
general.

B. What is the Agency's authority for taking this action?

    EPA is publishing this document in the Federal Register as required 
by sections 5 of the Toxic Substances Control Act (TSCA), 15 U.S.C. 
2601 et seq., and corresponding EPA regulations.
    Under TSCA, a chemical substance may be either an ``existing'' 
chemical substance or a ``new'' chemical substance, see <a href="https://www.epa.gov/chemicals-under-tsca">https://www.epa.gov/chemicals-under-tsca</a>. Any chemical substance that is not on 
EPA's TSCA Inventory of Chemical Substances (TSCA Inventory) is 
classified as a ``new chemical substance,'' while a chemical substance 
that is listed on the TSCA Inventory is classified as an ``existing 
chemical substance.'' See TSCA section 3(2) and (11). For more 
information about the TSCA Inventory, see <a href="https://www.epa.gov/tsca-inventory">https://www.epa.gov/tsca-inventory</a>.
    Any person who intends to manufacture (including import) a new 
chemical substance for a non-exempt commercial purpose, or to 
manufacture or process a chemical substance in a non-exempt manner for 
a use that EPA has determined is a significant new use, is required by 
TSCA section 5 to provide EPA with a PMN, MCAN, or SNUN, as 
appropriate, before initiating the activity. EPA will review the 
notice, make a risk determination on the new chemical substance or 
significant new use, and take appropriate action as described in TSCA 
section 5(a)(3).
    TSCA section 5(h)(1) authorizes EPA to allow persons, upon 
application and under appropriate restrictions, to manufacture a new 
chemical substance, or manufacture or process a chemical substance 
subject to a significant new use rule (SNUR) issued under TSCA section 
5(a)(2), for ``test marketing'' purposes, upon a showing that the 
manufacture, processing, distribution in commerce, use, and disposal of 
the chemical substances will not present an unreasonable risk of injury 
to health or the environment. This is referred to as a test marketing 
exemption, or TME.
    Premanufacture notification procedures for review of certain new 
microbial products of biotechnology are established in 40 CFR part 725. 
These pertain to MCANs and biotechnology exemptions, including TSCA 
experimental release applications (TERAs), TMEs for microorganisms, and 
Tier I and Tier II exemptions.

C. What action is the Agency taking?

    This document provides notice of receipt and status reports for the 
covered period and certain submissions under TSCA section 5 and 
provides an opportunity to comment on this information. The Agency is 
providing information about the receipt of PMNs, SNUNs, MCANs, and 
amendments to a previously submitted notice; test information; 
biotechnology exemption applications under 40 CFR part 725; TME 
applications; NOCs for new chemical substances; and a periodic status 
report on chemical substances that are currently under EPA review or 
have recently concluded review.

D. What should I consider as I prepare my comments for EPA?

    1. Submitting CBI. Do not submit CBI to EPA through <a href="https://www.regulations.gov">https://www.regulations.gov</a> or email. If you wish to include CBI in your 
comment, please follow the instructions at <a href="https://www.epa.gov/dockets/commenting-epa-dockets#rules">https://www.epa.gov/dockets/commenting-epa-dockets#rules</a> and clearly mark the information that you 
claim to be CBI. In addition to one complete version of the comment 
that includes CBI, a copy of the comment without CBI must be submitted 
for inclusion in the public docket. Information marked as CBI will not 
be disclosed except in accordance with procedures set forth in 40 CFR 
parts 2 and 703.
    2. Tips for preparing your comments. When preparing and submitting 
your comments, see the commenting tips at <a href="https://www.epa.gov/dockets/commenting-epa-dockets">https://www.epa.gov/dockets/commenting-epa-dockets</a>.

II. Background

A. What information is being provided in this document?

    The tables in this document provide the following information on 
the TSCA section 5 submissions received by EPA during this period and 
determined to be complete consistent with 40 CFR 720.70(a).
    <bullet> Case number. The EPA number assigned to the TSCA section 5 
submissions. Please note that a case number may be listed more than 
once in the table when the submission involves a subsequent amendment.
    <bullet> Chemical substance. Name of the chemical substance, or 
generic name if the specific name is claimed as CBI.
    <bullet> Manufacturer. Name of the submitting manufacturer, to the 
extent that such information is not subject to a CBI claim. The term 
``manufacturer'' is defined by statute to include importer.
    <bullet> Use(s). Potential uses identified by the manufacturer.
    <bullet> Received. Date the submission was received by EPA.
    <bullet> Commencement. Date of commencement provided by the 
submitter in the NOC.
    <bullet> Test information. For test information received, the type 
of test information submitted to EPA based on the attachment type and 
subtype data selected by the submitter.

B. What do the acronyms mean that are used in the tables?

    As used in each of the tables, the following explanations apply:
    <bullet> (S) indicates that the information in the table is the 
specific information provided by the submitter.
    <bullet> (G) indicates that the information in the table is generic 
information because the specific information provided by the submitter 
was claimed as CBI.

C. How can I access other information about TSCA section 5 submissions?

    EPA provides information on its website about cases reviewed under 
TSCA section 5, including the PMNs, SNUNs, MCANs, and exemption 
applications received; the date of receipt; the final EPA determination 
on the submission; and the effective date of EPA's determination. See 
<a href="https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices">https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices</a>. In addition, 
information EPA receives about chemical substances under TSCA, 
including non-CBI new chemical submissions, can be accessed in ChemView 
at <a href="https://chemview.epa.gov/chemview">https://chemview.epa.gov/chemview</a>.

III. Receipt Reports

    Table 1 provides non-CBI information for the PMNs, SNUNs and MCANs 
received by EPA that have passed an initial screening and determined to 
be complete consistent with 40 CFR 720.70(a) during this period.

[[Page 44064]]



                                Table 1--PMN/SNUN/MCANs Received and Under Review
----------------------------------------------------------------------------------------------------------------
           Case No.               Received date     Manufacturer             Use             Chemical substance
----------------------------------------------------------------------------------------------------------------
P-22-0071.....................  07/02/2025......  CBI.............  (G) Industrial         (S) D-Glucopyranose,
                                                                     Surfactant.            oligomeric,
                                                                                            maleates, C9-11-
                                                                                            alkyl glycosides,
                                                                                            sulfonated,
                                                                                            potassium salts.
P-22-0072.....................  07/02/2025......  CBI.............  (G) Industrial         (S) D-Glucopyranose,
                                                                     Surfactant.            oligomeric,
                                                                                            maleates, decyl
                                                                                            octyl glycosides,
                                                                                            sulfonated,
                                                                                            potassium salts.
P-22-0073.....................  07/02/2025......  CBI.............  (G) Industrial         (S) D-Glucopyranose,
                                                                     Surfactant.            oligomeric,
                                                                                            maleates, C10-16-
                                                                                            alkyl glycosides,
                                                                                            sulfonated,
                                                                                            potassium salts.
P-24-0006.....................  07/07/2025......  CBI.............  (S) Oilfield           (G) Propenoic acid,
                                                                     Production Scale       methyl-
                                                                     Inhibitor.             [phosphinicobis(oxy-
                                                                                            ethanediyl)] ester,
                                                                                            telomer with methyl-
                                                                                            methyl-propenoate,
                                                                                            (phosphonooxy) ethyl
                                                                                            methyl-propenoate,
                                                                                            propenoic acid,
                                                                                            sodium methyl-[(oxo-
                                                                                            propen-yl)amino]-
                                                                                            propanesulfonate and
                                                                                            sodium sulfite,
                                                                                            sodium salt,
                                                                                            peroxydisulfuric
                                                                                            acid sodium salt-
                                                                                            initiated.
P-24-0179.....................  07/15/2025......  CBI.............  (G) Component in       (G) Aluminum- and
                                                                     batteries.             metal-doped cobalt
                                                                                            metal nickel oxide.
P-24-0180.....................  07/15/2025......  CBI.............  (G) Component in       (G) Aluminum- and
                                                                     batteries.             metal- and metal-
                                                                                            doped cobalt metal
                                                                                            nickel oxide.
P-24-0181.....................  07/15/2025......  CBI.............  (G) Component in       (G) Metal- and metal-
                                                                     batteries.             doped cobalt metal
                                                                                            metal nickel oxide.
P-25-0025.....................  07/10/2025......  CBI.............  (G) Photolithography.  (G) Carbomonocyclic
                                                                                            alcohol, 4,4-[[6-
                                                                                            (heteroatom-
                                                                                            substituted
                                                                                            carbomonocycle)-
                                                                                            heteromonocycle-2,4-
                                                                                            diyl]heteroatom-
                                                                                            substituted] bis-.
P-25-0118.....................  07/01/2025......  CBI.............  (G) Liquid             (G) Neutral Protease.
                                                                     formulation and
                                                                     solid formulation of
                                                                     biocatalyst used in
                                                                     a variety of
                                                                     products.
P-25-0119.....................  07/03/2025......  Valerian          (S) Intermediate used  (S) -Methyl--
                                                   Materials, Inc.   for monomer            valerolactone.
                                                                     manufacturing, R&D
                                                                     chemical, Precursor
                                                                     monomer for polymers
                                                                     manufacturing.
                                                                     Industrial
                                                                     applications:
                                                                     Textiles, Coatings
                                                                     and Paints,
                                                                     Sealants, Footwear.
P-25-0120.....................  07/03/2025......  CBI.............  (G) Ink, pellet and    (G) Butanamide,
                                                                     paint component.       [(dialkoxy[biscarbom
                                                                                            onocyclic]-diyl)
                                                                                            bis(substituted)]
                                                                                            bis [(halo-dialkoxy
                                                                                            carbomonocycle)-
                                                                                            substituted.
P-25-0121.....................  07/08/2025......  CBI.............  (G) Ink component,     (G) Butanamide,
                                                                     Ingredient in ink.     [(dihalo[biscarbomon
                                                                                            ocyclic]-diyl)
                                                                                            bis(substituted)]
                                                                                            bis [substituted,
                                                                                            bis [substituted
                                                                                            carbomonocycle and
                                                                                            carbomonocyclic]
                                                                                            derivs.
P-25-0122.....................  07/09/2025......  CBI.............  (G) Ink, pellet and    (G) Butanamide,
                                                                     paint component.       [(dihalo[biscarbomon
                                                                                            ocyclic]-diyl)
                                                                                            bis(substituted)]
                                                                                            bis [substituted,
                                                                                            bis [substituted
                                                                                            carbomonocycle and
                                                                                            halo-dialkoxy
                                                                                            carbomonocyclic]
                                                                                            derivs.
P-25-0123.....................  07/18/2025......  CBI.............  (G) Ink component,     (G) Butanamide, 2,2'-
                                                                     Ingredient in ink.     [(dihalo[1,1'-
                                                                                            biphenyl]-4,4'-diyl)
                                                                                            bis(2,1-
                                                                                            diazenediyl)] bis [3-
                                                                                            oxo, N,N'-bis
                                                                                            (substituted
                                                                                            heteropolycyclic and
                                                                                            alkyl
                                                                                            carbomonocyclic)
                                                                                            derivs.
P-25-0124.....................  07/18/2025......  CBI.............  (G) Additive for use   (G) Alkyl aromatic
                                                                     in electronics         sulfonium,
                                                                     industry.              polycyclic alkyl
                                                                                            sulfamate.
P-25-0125.....................  07/18/2025......  CBI.............  (G) Substance for the  (G) Cobalt lithium
                                                                     use in manufacturing   manganese nickel
                                                                     of battery             oxide, metals.
                                                                     components.
P-25-0126.....................  07/18/2025......  CBI.............  (G) An ingredient      (G) Carbomonocyclic
                                                                     used in the            substituted
                                                                     manufacture of         heteromonocyclic,
                                                                     photoresist.           salt with
                                                                                            carbopolycyclic
                                                                                            sulfocarboxylate.
P-25-0127.....................  07/18/2025......  CBI.............  (G) An ingredient      (G) Carbomonocyclic
                                                                     used in the            sulfonium, salt with
                                                                     manufacture of         carbopolycyclic
                                                                     photoresist.           sulfocarboxylate.

[[Page 44065]]

 
P-25-0128.....................  07/21/2025......  CBI.............  (G) Photolithography.  (G) 2-Propenoic acid,
                                                                                            2-methyl-, halo
                                                                                            alkyl ester, polymer
                                                                                            with
                                                                                            ethenylcarbomonocycl
                                                                                            ic alcohol, dimethyl
                                                                                            2,2-(1,2-
                                                                                            diazenediyl) bis [2-
                                                                                            alkyl ester]-
                                                                                            initiated.
SN-25-0006....................  07/24/2025......  CBI.............  (S) Substance for use  (S) Phosphoric acid,
                                                                     in the manufacture     iron (2+) lithium
                                                                     of battery cathodes.   salt (1:1:1).
SN-25-0007....................  07/01/2025......  Essential         (G) Additive used in   (S) Propanoic acid, 3-
                                                   Industries, Inc.  commercial and         hydroxy-2-
                                                                     consumer               (hydroxymethyl)-2-
                                                                     applications.          methyl-, polymer
                                                                                            with dimethyl
                                                                                            carbonate, 1,2-
                                                                                            ethanediamine, 2-
                                                                                            ethyl-2-
                                                                                            (hydroxymethyl)-1,3-
                                                                                            propanediol, 1,6-
                                                                                            hexanediol and 1,1'-
                                                                                            methylenebis[4-
                                                                                            isocyanatocyclohexan
                                                                                            e], compd. with N,N-
                                                                                            diethylethanamine.
----------------------------------------------------------------------------------------------------------------

    Table 2 provides non-CBI information on the NOCs received by EPA 
that have passed an initial screening during this period.

                                     Table 2--NOCs Received and Under Review
----------------------------------------------------------------------------------------------------------------
              Case No.                    Received date         Commencement date         Chemical substance
----------------------------------------------------------------------------------------------------------------
P-16-0408..........................  07/09/2025............  05/31/2022............  (G) Benzyloxy)-nitrophenyl
                                                                                      diazen-1-yl]-hydroxy-
                                                                                      dimethyl-2-oxo-
                                                                                      dihydropyridine-
                                                                                      carbonitrile.
P-21-0184..........................  07/23/2025............  07/22/2025............  (S) Fatty acids, Soya,
                                                                                      reaction products with
                                                                                      ammonia-ethanolamine
                                                                                      reaction by-products.
P-23-0044..........................  07/31/2025............  07/18/2025............  (G) Monoaromatic cyclic
                                                                                      alkylene sulfonium
                                                                                      fluoroalkyl sulfonic acid
                                                                                      salt.
P-23-0080..........................  07/31/2025............  07/18/2025............  (G) Aromatic sulfonium
                                                                                      tricyclo fluoroalkyl
                                                                                      sulfonic acid salt.
P-23-0168..........................  07/29/2025............  12/20/2024............  (G) Sulfamide
                                                                                      fluorophosphate salt.
P-24-0079..........................  07/30/2025............  07/29/2025............  (G) Alkylated succinimide.
P-25-0066..........................  07/24/2025............  06/25/2025............  (G) Sulfonium, bis (dihalo
                                                                                      carbomonocycle)
                                                                                      carbomonocycle-, salt with
                                                                                      dihalo-sulfoalkyl-
                                                                                      [(alkenylcarbomonocycle)su
                                                                                      bstituted] trisubstituted
                                                                                      benzoate, polymer with
                                                                                      alkenylcarbomonocycle and
                                                                                      alkylcarbomonocycle alkyl
                                                                                      alkenoate.
P-25-0067..........................  07/24/2025............  06/25/2025............  (G) Sulfonium, bis (dihalo
                                                                                      carbomonocycle)
                                                                                      carbomonocycle-, salt with
                                                                                      trihalobenzoate.
----------------------------------------------------------------------------------------------------------------

    Table 3 provides non-CBI information on the test information that 
has been received by EPA that have passed an initial screening during 
this period.

                                       Table 3--Test Information Received
----------------------------------------------------------------------------------------------------------------
             Case No.                  Received date     Type of test information        Chemical substance
----------------------------------------------------------------------------------------------------------------
L-25-0030........................  07/25/2025..........  Supplemental information  (G) 2-Alkanone, halo-1,1,1-
                                                                                    trifluoro-.
P-14-0712........................  06/30/2025..........  Polychlorinated           (S) Waste plastics,
                                                          Dibenzodioxins and        pyrolyzed, C5-55 fraction.
                                                          Polychlorinated
                                                          Dibenzofurans Testing.
P-16-0543........................  07/23/2025..........  Monitoring Report.......  (G) Halogenophosphoric acid
                                                                                    metal salt.
P-18-0016........................  07/18/2025..........  Photo transformation of   (G) Aromatic sulfonium
                                                          Chemicals in Water--      tricyclo fluoroalkyl
                                                          Direct Photolysis (OECD   sulfonic acid salt.
                                                          Test Guideline 316).
P-19-0166........................  07/23/2025..........  Partition Coefficient (1- (G) Triaryl sulfonium,
                                                          Octanol/Water): Slow-     multicycloalkylalkoxycarbony
                                                          Stirring Method (OECD     loxymonofluoroalkylsulfonate
                                                          Test Guideline 123);      .
                                                          Photo transformation of
                                                          Chemicals in Water--
                                                          Direct Photolysis (OECD
                                                          Test Guideline 316).
P-20-0042........................  07/18/2025..........  Photo transformation of   (G) Sulfonium, trisaryl-, 7,7-
                                                          Chemicals in Water--      dialkyl-2-heteropolycyclic -
                                                          Direct Photolysis (OECD   1-alkanesulfonate (1:1).
                                                          Test Guideline 316).

[[Page 44066]]

 
P-20-0159, P-20-0147, P-20-0152,   07/28/2025..........  Test data...............  (G) Phenoxathiin ium, 10-
 P-20-0155.                                                                         phenyl, 5-alkyl-2-alkyl-4-
                                                                                    (2,4,6-substituted tri-
                                                                                    carbomonocycle, hetero-
                                                                                    acid)benzenesulfonate (1:1);
                                                                                    (G) Substituted-2H-
                                                                                    thiopyrylium, salt with
                                                                                    fluoroalkyl tricycloalkane-
                                                                                    carboxylate (1:1); (G)
                                                                                    Sulfonium, triphenyl-, salt
                                                                                    with 2,2-difluoro-2-
                                                                                    sulfoethyl-2-oxo substituted
                                                                                    -heterotricycloalkane-
                                                                                    heteropolycycle-carboxylate
                                                                                    (1:1); (G) Sulfonium,
                                                                                    triphenyl-, salt with 5-
                                                                                    alkyl- 2-alkyl- 4-(2,4,6-
                                                                                    substituted tri-
                                                                                    carbomonocycle, hetero-
                                                                                    acid)benzenesulfonate (1:1).
P-21-0202........................  07/23/2025..........  Water Solubility (Shake   (G) Sulfonium, carbomonocycle
                                                          Flask Method) (OECD       bis [(Tri haloalkyl)
                                                          Test Guideline 105);      carbomonocycle], substituted
                                                          Partition Coefficient     carbomonocyclic ester.
                                                          (n-Octanol/Water):
                                                          Shake Flask Method
                                                          (OECD Test Guideline
                                                          107); Dissociation
                                                          Constants in Water
                                                          (Conductometric Method)
                                                          (OECD Test Guideline
                                                          112).
P-22-0055........................  07/18/2025..........  Photo transformation of   (G) Aromatic sulfonium
                                                          Chemicals in Water--      tricyclo fluoroalkyl
                                                          Direct Photolysis (OECD   sulfonic acid salt.
                                                          Test Guideline 316).
P-22-0087........................  07/23/2025..........  in Vitro Skin             (S) Fatty acids, C18-unsatd.,
                                                          Irritation:               dimers, polymers with
                                                          Reconstructed Human       acrylic acid, bisphenol A,
                                                          Epidermis Test Method     epichlorohydrin, oleic acid,
                                                          (OECD Test Guideline      2,2'-[oxybis(methylene)]
                                                          439); in Vitro Skin       bis[2-ethyl-1,3-propanediol]
                                                          Corrosion:                and phthalic anhydride.
                                                          Reconstructed Human
                                                          Epidermis (RHE) Test
                                                          Method (OECD Test
                                                          Guideline 431).
P-22-0129, P-20-0140, P-20-0141,   07/28/2025..........  Determination of n-       (G) Substituted heterocyclic
 P-20-0142, P-20-0145.                                    Octanol/Water Partition   onium compound, salt with
                                                          Coefficient (Slow Stir    heteropolysubstitutedalkyl
                                                          Method).                  substitutedtricycloalkane
                                                                                    carboxylate (1:1), polymer
                                                                                    with 1-alkenyl4-[(alkyl
                                                                                    cycloalkyl)oxy]carbomonocycl
                                                                                    e, 5-ethyloctahydro-4,7-
                                                                                    methano-1H-inden-5-yl 2-
                                                                                    methyl-2-propenoate,
                                                                                    hexahydro-5-oxo-2,6-
                                                                                    methanofuro[3,2-b]furan-3-yl
                                                                                    2-methyl-2-propenoate and 4-
                                                                                    hydroxyphenyl 2-methyl-2-
                                                                                    propenoate; (G) N-
                                                                                    Substituted-beta-alanine,
                                                                                    heterosubstituted-alkyl
                                                                                    ester, ion(1-),
                                                                                    triphenylsulfonium (1:1);
                                                                                    (G) Sulfonium, [4-(1,1-
                                                                                    dimethylethyl)phenyl]dipheny
                                                                                    l-, salt with
                                                                                    heterosubstituted-alkyl Tri
                                                                                    cycloalkane-carboxylate
                                                                                    (1:1); (G) Dibenz
                                                                                    thiophenium, 5-phenyl-, salt
                                                                                    with 2,2-difluoro-2-
                                                                                    sulfoethyl substituted-
                                                                                    heterotricycloalkane-
                                                                                    carboxylate (1:1); (G)
                                                                                    Substituted heterocyclic
                                                                                    onium compound, salt with
                                                                                    fluoropoly substitutedalkyl
                                                                                    substituted Tri cycloalkane
                                                                                    carboxylate (1:1), polymer
                                                                                    with disubstituted aromatic
                                                                                    compound and 1-
                                                                                    methylcyclopentyl 2-methyl-2-
                                                                                    propenoate, di-Me 2,2'-(1,2-
                                                                                    diazenediyl)bis[2-
                                                                                    methylpropanoate]-initiated.
P-23-0037........................  07/18/2025..........  Photo transformation of   (G) Monoaromatic cyclic
                                                          Chemicals in Water--      alkylene sulfonium
                                                          Direct Photolysis (OECD   fluoroalkyl sulfonic acid
                                                          Test Guideline 316).      salt.
P-23-0044........................  07/18/2025..........  Photo transformation of   (G) Monoaromatic cyclic
                                                          Chemicals in Water--      alkylene sulfonium
                                                          Direct Photolysis (OECD   fluoroalkyl sulfonic acid
                                                          Test Guideline 316).      salt.
P-23-0050, P-19-0114, P-19-0133,   07/28/2025..........  Test data...............  (G) Substituted heterocyclic
 P-20-0122, P-20-0139.                                                              onium compound, salt with
                                                                                    heteropolysubstitutedalkylsu
                                                                                    bstitutedtricycloalkanecarbo
                                                                                    xylate (1:1), polymer with 3-
                                                                                    ethenylphenol and
                                                                                    heterosubstitutedaromaticalk
                                                                                    yl 2-methyl-2-propenoate, di-
                                                                                    Me 2,2'-(1,2-
                                                                                    diazenediyl)bis[2-
                                                                                    methylpropanoate]-initiated;
                                                                                    (G) Sulfonium, triphenyl-,
                                                                                    trifluoro-hydroxy-
                                                                                    (triheterosubstitutedalkyl)a
                                                                                    lkanoate (1:1); (G)
                                                                                    Heterodisubstituted-bile
                                                                                    acid, 1-
                                                                                    (difluorosulfomethyl)-2,2,2-
                                                                                    trifluoroethyl ester, ion(1-
                                                                                    ), (5)-, triphenylsulfonium
                                                                                    (1:1); (G) Heterocyclic
                                                                                    onium compound with fluoro
                                                                                    substitutedalkyl 2-methyl-2-
                                                                                    propenoate (1:1), polymer
                                                                                    with acenaphthylene, 4-
                                                                                    ethenyl-alpha,
                                                                                    alphadimethylbenzenemethanol
                                                                                    and 4-ethenylphenyl acetate,
                                                                                    hydrolyzed; (G) Sulfonium,
                                                                                    triphenyl-, 1,2-
                                                                                    fluoroalkyltricycloalkyl-1-
                                                                                    carboxylate (1:1).

[[Page 44067]]

 
P-23-0080........................  07/18/2025..........  Photo transformation of   (G) Aromatic sulfonium
                                                          Chemicals in Water--      tricyclo fluoroalkyl
                                                          Direct Photolysis (OECD   sulfonic acid salt.
                                                          Test Guideline 316).
P-23-0093........................  07/18/2025..........  Photo transformation of   (G) Aromatic
                                                          Chemicals in Water--      Dibenzothiophenium
                                                          Direct Photolysis (OECD   fluoroalkyl carbopolycycle
                                                          Test Guideline 316).      sulfonic acid salt.
P-24-0160........................  07/18/2025..........  Photo transformation of   (G) Iodonium, bis (dialkyl
                                                          Chemicals in Water--      carbomonocycle) salt with
                                                          Direct Photolysis (OECD   alkyl carbomonocycle hetero
                                                          Test Guideline 316).      acid.
P-24-0185, P-19-0078, P-19-0079,   07/28/2025..........  Determination of n-       (G) Sulfonium, triphenyl-,
 P-19-0111, P-19-0112.                                    Octanol/Water Partition   salt with fluoro sulfoalkyl-
                                                          Coefficient (Slow Stir    fluoroalkyl substituted-
                                                          Method).                  heterotricycloalkane-
                                                                                    carboxylate (1:1); (G)
                                                                                    Substituted heterocyclic
                                                                                    onium compound, salt with
                                                                                    2,2,2-trifluoro-1-
                                                                                    (sulfomethyl)-1-
                                                                                    (trifluoromethyl)ethyl 3-[(2-
                                                                                    methyl-1-oxo-2-propen-1-
                                                                                    yl)oxy]tricycle[3.3.1.13,7]d
                                                                                    ecane-1-carboxylate (1:1),
                                                                                    polymer with acenaphthylene,
                                                                                    1-ethenyl-4-[(1-
                                                                                    ethylcyclopentyl)oxy]benzene
                                                                                    and 4- ethenylphenol, di-Me
                                                                                    2,2'-(1,2-diazenediyl)bis[2-
                                                                                    methylpropanoate]-initiated;
                                                                                    (G) substituted heterocyclic
                                                                                    onium compound, salt with
                                                                                    2,2,2-trifluoro-1-
                                                                                    (sulfomethyl)-1-
                                                                                    (trifluoromethyl)ethyl 3-[(2-
                                                                                    methyl-1-oxo-2-propen-1-
                                                                                    yl)oxy]tricyclo[3.3.1.13,7]d
                                                                                    ecane-1-carboxylate (1:1),
                                                                                    polymer with acenaphthylene,
                                                                                    1-ethenyl-4-[[1-(1-
                                                                                    methylethyl)cyclopentyl]oxy]
                                                                                    benzene and 4-ethenylphenol,
                                                                                    di-Me 2,2'-(1,2-
                                                                                    diazenediyl)bis[2-
                                                                                    methylpropanoate]-initiated;
                                                                                    (G) Dibenzothiophenium,
                                                                                    trifluoro-hydroxy-
                                                                                    (triheterosubstitutedalkyl)a
                                                                                    lkanoate (1:1); (G)
                                                                                    Substituted heterocyclic
                                                                                    onium compound, salt with 1-
                                                                                    (difluorosulfomethyl)-2,2,2-
                                                                                    trifluoroethyl 3-[(2-methyl-
                                                                                    1-oxo-2-propen-1-
                                                                                    yl)oxy]tricyclo[3.3.1.13,7]d
                                                                                    ecane-1-carboxylate (1:1),
                                                                                    polymer with 3-etheylphenol,
                                                                                    1-(1-methylethyl)cyclopentyl
                                                                                    2-methyl-2-propenoate and 1-
                                                                                    (7- oxabicyclo[2.2.1]hept-2-
                                                                                    yl)cyclopentyl 2-methyl-2-
                                                                                    propenoate, di-Me 2,2'-(1,2-
                                                                                    diazenediyl)bis[2-
                                                                                    methylpropenoate]-initiated.
P-24-0190........................  07/18/2025..........  Photo transformation of   (G) Aromatic sulfonium
                                                          Chemicals in Water--      tricyclo salt with alkyl
                                                          Direct Photolysis (OECD   carbomonocycle hetero acid.
                                                          Test Guideline 316).
P-25-0016........................  07/18/2025..........  Photo transformation of   (G) Tri haloaromatic iodonium
                                                          Chemicals in Water--      dicyclo salt with
                                                          Direct Photolysis (OECD   polyhaloalkyl carbomonocycle
                                                          Test Guideline 316).      hetero acid.
P-25-0028, P-17-0178, P-18-0013,   07/29/2025..........  Determination of n-       (G) Heteroonium,
 P-18-0014, P-18-0037.                                    Octanol/Water Partition   tri(substitutedaromatichydro
                                                          Coefficient (Slow Stir    carbon)-, nitrate (1:1); (G)
                                                          Method).                  Sulfonium, triphenyl-, salt
                                                                                    with substituted-alkyl 4-
                                                                                    substituted-benzoate; (G)
                                                                                    Sulfonium, pheno
                                                                                    carbopolycycle, inner salt;
                                                                                    (G) Sulfonium, triphenyl-,
                                                                                    salt with disubstituted-
                                                                                    heterocyclic compound (1:1);
                                                                                    (G) Sulfonium, triphenyl-,
                                                                                    salt with 2,4,5-
                                                                                    trisubstituted-
                                                                                    benzenesulfonate (1:1).
P-25-0066........................  07/23/2025..........  Water Solubility (Shake   (G) Sulfonium, bis (dihalo
                                                          Flask Method) (OECD       carbomonocycle)
                                                          Test Guideline 105);      carbomonocycle-, salt with
                                                          Partition Coefficient     dihalo-sulfoalkyl
                                                          (n-Octanol/Water):        [(alkenylcarbomonocycle)subs
                                                          Shake Flask Method        tituted] trisubstituted
                                                          (OECD Test Guideline      benzoate, polymer with
                                                          107); Dissociation        alkenylcarbomonocycle and
                                                          Constants in Water        alkylcarbomonocycle alkyl
                                                          (Conductometric Method)   alkenoate.
                                                          (OECD Test Guideline
                                                          112).
P-25-0067........................  07/23/2025..........  Water Solubility (Shake   (G) Sulfonium, bis (dihalo
                                                          Flask Method) (OECD       carbomonocycle)
                                                          Test Guideline 105);      carbomonocycle-, salt with
                                                          Partition Coefficient     trihalobenzoate.
                                                          (n-Octanol/Water):
                                                          Shake Flask Method
                                                          (OECD Test Guideline
                                                          107); Dissociation
                                                          Constants in Water
                                                          (Conductometric Method)
                                                          (OECD Test Guideline
                                                          112).
P-25-0097........................  07/18/2025..........  Photo transformation of   (G) Aromatic sulfonium
                                                          Chemicals in Water--      tricyclo salt with
                                                          Direct Photolysis (OECD   dicycloalkyl carbomonocycle
                                                          Test Guideline 316).      hetero acid.

[[Page 44068]]

 
P-25-0100........................  07/18/2025..........  Photo transformation of   (G) Aromatic sulfonium
                                                          Chemicals in Water--      tricyclo salt with alkyl
                                                          Direct Photolysis (OECD   carbomonocycle hetero acid.
                                                          Test Guideline 316).
P-25-0102........................  07/18/2025..........  Photo transformation of   (G) Carboheterocyclo aromatic
                                                          Chemicals in Water--      sulfonium salt with
                                                          Direct Photolysis (OECD   dicycloalkyl carbomonocycle
                                                          Test Guideline 316).      hetero acid.
P-25-0110........................  07/29/2025..........  28 Day Repeated Dose
                                                          Oral Toxicity Study in
                                                          Rats, IUCLID Summaries,
                                                          Vapor Pressure Report,
                                                          Statement of
                                                          environmental
                                                          monitoring test, Acute
                                                          Dermal Toxicity in
                                                          Rats, Activated Sludge
                                                          Respiration Inhibition
                                                          Test, OECD-HT Vapor
                                                          Pressure, Adsorption
                                                          coefficient on soil and
                                                          sewage sludge, Ready
                                                          Biodegradability-CO2
                                                          evolution, Daphnia
                                                          magna reproduction
                                                          study, Fish acute
                                                          toxicity study, In
                                                          vitro mammalian cell
                                                          gene mutation study,
                                                          Prenatal developmental
                                                          toxicity study,
                                                          Physical Chemical
                                                          Properties 2, OECD HT
                                                          Adsorption coefficient,
                                                          OECD HT Hydrolysis as a
                                                          function of pH, OECD HT
                                                          Partition Coefficient,
                                                          OECD HT Water
                                                          Solubility.
P-25-0111........................  07/18/2025..........  Photo transformation of   (G) Haloaromatic iodonium
                                                          Chemicals in Water--      dicyclo salt with
                                                          Direct Photolysis (OECD   polyfluoroalkyl
                                                          Test Guideline 316).      carbomonocycle hetero acid.
P-25-0112........................  07/18/2025..........  Photo transformation of   (G) Haloaromatic iodonium
                                                          Chemicals in Water--      dicyclo salt with
                                                          Direct Photolysis (OECD   halogenated hydroxyaryl
                                                          Test Guideline 316).      carboxylic acid.
----------------------------------------------------------------------------------------------------------------

IV. Status Reports

    Information about the TSCA section 5 PMNs, SNUNs, MCANs, and 
exemption applications received, including the date of receipt, the 
status of EPA's review, the final EPA determination, and the effective 
date of EPA's determination, is available online at: <a href="https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices">https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca/status-pre-manufacture-notices</a>.
    Authority: 15 U.S.C. 2601 et seq.

    Dated: September 9, 2025.
Mary Elissa Reaves,
Director, Office of Pollution Prevention and Toxics.
[FR Doc. 2025-17563 Filed 9-10-25; 8:45 am]
BILLING CODE 6560-50-P


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Indexed from Federal Register on September 11, 2025.

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