Notice2025-16245

Prescription Drug User Fee Act and Biosimilar User Fee Amendments Hiring and Retention Assessment; Public Meeting; Request for Comments

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Published
August 25, 2025

Issuing agencies

Health and Human Services DepartmentFood and Drug Administration

Abstract

The Food and Drug Administration (FDA, the Agency, or we) is announcing the following public meeting entitled "Prescription Drug User Fee Act and Biosimilar User Fee Amendments Hiring and Retention Assessment." The topic to be discussed is a hiring and retention assessment which was performed by an independent contractor.

Full Text

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<title>Federal Register, Volume 90 Issue 162 (Monday, August 25, 2025)</title>
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[Federal Register Volume 90, Number 162 (Monday, August 25, 2025)]
[Notices]
[Pages 41395-41397]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-16245]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Food and Drug Administration

[Docket No. FDA-2025-N-2962]


Prescription Drug User Fee Act and Biosimilar User Fee Amendments 
Hiring and Retention Assessment; Public Meeting; Request for Comments

AGENCY: Food and Drug Administration, HHS.

ACTION: Notice of public meeting; request for comments.

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SUMMARY: The Food and Drug Administration (FDA, the Agency, or we) is 
announcing the following public meeting entitled ``Prescription Drug 
User Fee Act and Biosimilar User Fee Amendments Hiring and Retention 
Assessment.'' The topic to be discussed is a hiring and retention 
assessment

[[Page 41396]]

which was performed by an independent contractor.

DATES: The public meeting will be held in person and virtually on 
September 24, 2025, from 9 a.m. to 12 p.m. Eastern Time. Either 
electronic or written comments on this public meeting must be submitted 
by October 24, 2025. See the SUPPLEMENTARY INFORMATION section for 
registration date and information.

ADDRESSES: The public meeting will be held in person at the FDA White 
Oak Campus, 10903 New Hampshire Ave., Bldg. 31 Conference Center, the 
Great Room, Silver Spring, MD 20993-0002 and virtually using the 
Microsoft Teams platform. Participants must be REAL ID compliant to 
access federal facilities. For additional information regarding REAL 
ID, refer to <a href="https://www.dhs.gov/real-id/real-id-faqs">https://www.dhs.gov/real-id/real-id-faqs</a>. Entrance for the 
public meeting participants (non-FDA employees) is through Building 1 
where routine security check procedures will be performed. For parking 
and security information, please refer to <a href="https://www.fda.gov/about-fda/visitor-information">https://www.fda.gov/about-fda/visitor-information</a>. Any changes to the public meeting location and 
remote information, as appropriate, will be posted to <a href="https://www.fda.gov/drugs/news-events-human-drugs/prescription-drug-user-fee-act-and-biosimilar-user-fee-amendments-hiring-and-retention-assessment">https://www.fda.gov/drugs/news-events-human-drugs/prescription-drug-user-fee-act-and-biosimilar-user-fee-amendments-hiring-and-retention-assessment</a> 
in advance of the meeting.
    You may submit comments as follows. Please note that late, untimely 
filed comments will not be considered. The <a href="https://www.regulations.gov">https://www.regulations.gov</a> 
electronic filing system will accept comments until 11:59 p.m. Eastern 
Time at the end of October 24, 2025. Comments received by mail/hand 
delivery/courier (for written/paper submissions) will be considered 
timely if they are received on or before that date.

Electronic Submissions

    Submit electronic comments in the following way:
    <bullet> Federal eRulemaking Portal: <a href="https://www.regulations.gov">https://www.regulations.gov</a>. 
Follow the instructions for submitting comments. Comments submitted 
electronically, including attachments, to <a href="https://www.regulations.gov">https://www.regulations.gov</a> 
will be posted to the docket unchanged. Because your comment will be 
made public, you are solely responsible for ensuring that your comment 
does not include any confidential information that you or a third party 
may not wish to be posted, such as medical information, your or anyone 
else's Social Security number, or confidential business information, 
such as a manufacturing process. Please note that if you include your 
name, contact information, or other information that identifies you in 
the body of your comments, that information will be posted on <a href="https://www.regulations.gov">https://www.regulations.gov</a>.
    <bullet> If you want to submit a comment with confidential 
information that you do not wish to be made available to the public, 
submit the comment as a written/paper submission and in the manner 
detailed (see ``Written/Paper Submissions'' and ``Instructions'').

Written/Paper Submissions

    Submit written/paper submissions as follows:
    <bullet> Mail/Hand Delivery/Courier (for written/paper 
submissions): Dockets Management Staff (HFA-305), Food and Drug 
Administration, 5630 Fishers Lane, Rm. 1061, Rockville, MD 20852.
    <bullet> For written/paper comments submitted to the Dockets 
Management Staff, FDA will post your comment, as well as any 
attachments, except for information submitted, marked and identified, 
as confidential, if submitted as detailed in ``Instructions.''
    Instructions: All submissions received must include the Docket No. 
FDA-2025-N-2962 for ``Prescription Drug User Fee Act and Biosimilar 
User Fee Amendments Hiring and Retention Assessment; Public Meeting; 
Request for Comments.'' Received comments, those filed in a timely 
manner (see ADDRESSES), will be placed in the docket and, except for 
those submitted as ``Confidential Submissions,'' publicly viewable at 
<a href="https://www.regulations.gov">https://www.regulations.gov</a> or at the Dockets Management Staff between 
9 a.m. and 4 p.m., Monday through Friday, 240-402-7500.
    <bullet> Confidential Submissions--To submit a comment with 
confidential information that you do not wish to be made publicly 
available, submit your comments only as a written/paper submission. You 
should submit two copies total. One copy will include the information 
you claim to be confidential with a heading or cover note that states 
``THIS DOCUMENT CONTAINS CONFIDENTIAL INFORMATION.'' The Agency will 
review this copy, including the claimed confidential information, in 
its consideration of comments. The second copy, which will have the 
claimed confidential information redacted/blacked out, will be 
available for public viewing and posted on <a href="https://www.regulations.gov">https://www.regulations.gov</a>. 
Submit both copies to the Dockets Management Staff. If you do not wish 
your name and contact information to be made publicly available, you 
can provide this information on the cover sheet and not in the body of 
your comments and you must identify this information as 
``confidential.'' Any information marked as ``confidential'' will not 
be disclosed except in accordance with 21 CFR 10.20 and other 
applicable disclosure law. For more information about FDA's posting of 
comments to public dockets, see 80 FR 56469, September 18, 2015, or 
access the information at: <a href="https://www.govinfo.gov/content/pkg/FR-2015-09-18/pdf/2015-23389.pdf">https://www.govinfo.gov/content/pkg/FR-2015-09-18/pdf/2015-23389.pdf</a>.
    Docket: For access to the docket to read background documents or 
the electronic and written/paper comments received, go to <a href="https://www.regulations.gov">https://www.regulations.gov</a> and insert the docket number, found in brackets in 
the heading of this document, into the ``Search'' box and follow the 
prompts and/or go to the Dockets Management Staff, 5630 Fishers Lane, 
Rm. 1061, Rockville, MD 20852, 240-402-7500.

FOR FURTHER INFORMATION CONTACT: Thamar Bailey, Center for Drug 
Evaluation and Research, Food and Drug Administration, 10903 New 
Hampshire Ave., Bldg. 32, Rm. 4103, Silver Spring, MD 20993-0002, 301-
796-6645, <a href="/cdn-cgi/l/email-protection#c68582839496b4a9a1b4a7ab83b0a7aab3a7b2afa9a886a0a2a7e8aeaeb5e8a1a9b0"><span class="__cf_email__" data-cfemail="bbf8fffee9ebc9d4dcc9dad6fecddad7cedacfd2d4d5fbdddfda95d3d3c895dcd4cd">[email&#160;protected]</span></a>.

SUPPLEMENTARY INFORMATION:

I. Background

    FDA is holding a public meeting to meet performance commitments 
included in the Prescription Drug User Fee Act (PDUFA VII) and the 
Biosimilar User Fee Amendments (BsUFA III). These user fee programs 
were reauthorized for fiscal years 2023-2027 as part of the FDA User 
Fee Reauthorization Act of 2022 (Pub. L. 117-180) enacted on September 
30, 2022. The complete set of performance goals for each program is 
available at:

<bullet> PDUFA VII program: <a href="https://www.fda.gov/media/151712/download">https://www.fda.gov/media/151712/download</a>
<bullet> BsUFA III program: <a href="https://www.fda.gov/media/152279/download">https://www.fda.gov/media/152279/download</a>

    During the public meeting, FDA will share high-level findings from 
a recently completed assessment of FDA's hiring and retention of staff 
for the human drug review program. This assessment was conducted by a 
qualified, independent contractor with expertise in assessing Human 
Resource (HR) and Human Capital (HC) operations as agreed to in the 
PDUFA VII and BsUFA III commitment letters. Previously, as part of 
PDUFA VI and BsUFA II, independent contractors conducted a series of 
three assessments that aimed to capture the status of FDA's HR and HC 
operations, identify challenges, and provide actionable 
recommendations. The previous reports are available at:


[[Page 41397]]


<bullet> Initial assessment report: <a href="https://www.fda.gov/media/108866/download">https://www.fda.gov/media/108866/download</a>
<bullet> Interim assessment report: <a href="https://www.fda.gov/media/138662/download">https://www.fda.gov/media/138662/download</a>
<bullet> Final assessment report: <a href="https://www.fda.gov/media/154873/download">https://www.fda.gov/media/154873/download</a>

    The initial assessment served as a baseline, evaluated the state of 
FDA human resource operations, identified root causes of challenges, 
and provided recommendations related to recruitment and hiring. Unlike 
the subsequent evaluations, the initial assessment did not evaluate 
employee retention efforts. The interim and final assessments 
documented progress from the previous assessment(s) related to 
recommendations from the initial assessment, program milestones, 
metrics, and other aggregated feedback from internal HR/HC customers 
and participants and provided additional recommendations. The current 
assessment builds upon the findings from the three previous assessments 
with a focus on changes that have improved FDA's hiring and retention 
outcomes and challenges that remain. The current assessment also 
expands beyond the scope of the previous assessments to include the 
pre-employment onboarding process. This assessment report includes 
metrics related to recruiting and retention in the human drug review 
program, including specific targeted scientific disciplines, attrition, 
and utilization of pay authorities. The report also includes the 
contractor's findings and recommendations on further enhancements to 
hiring and retention of staff for the human drug review program. To 
view the assessment report, please visit: <a href="https://www.fda.gov/media/188083">https://www.fda.gov/media/188083</a>.

II. Topics for Discussion at the Public Meeting

    This public meeting will provide FDA the opportunity to update 
interested public stakeholders on topics related to hiring and 
retention in the FDA human drug review program. The independent 
contractor will present their findings and recommendations that are 
outlined in the hiring and retention assessment report, and FDA will 
provide its perspective on the independent contractor's findings and 
recommendations. To view the assessment report, please visit: <a href="https://www.fda.gov/media/188083">https://www.fda.gov/media/188083</a>.

III. Participating in the Public Meeting

    Registration: To register for this hybrid public meeting, please 
visit the following website: <a href="https://FDAPublicMeeting_PDUFAVII_BsUFAIII_HiringandRetention.eventbrite.com">https://FDAPublicMeeting_PDUFAVII_BsUFAIII_HiringandRetention.eventbrite.com</a>. 
Please provide complete contact information for each attendee, 
including attendance format (in-person or virtual), name, title, 
affiliation, and email.
    Registration is free and based on space availability, with priority 
given to early registrants. Persons interested in attending the public 
meeting must register by September 15, 2025, 11:59 p.m. Eastern Time. 
Early registration is recommended because seating is limited; 
therefore, FDA may limit the number of participants from each 
organization. Registrants will receive confirmation when they have been 
accepted. If time and space permit, onsite registration on the day of 
the public meeting will be provided beginning at 8 a.m.
    If you need special accommodations due to a disability, please 
contact Thamar Bailey, 301-796-6645, <a href="/cdn-cgi/l/email-protection#1d5e59584f4d6f727a6f7c70586b7c71687c697472735d7b797c3375756e337a726b"><span class="__cf_email__" data-cfemail="581b1c1d0a082a373f2a39351d2e39342d392c313736183e3c397630302b763f372e">[email&#160;protected]</span></a> 
no later than September 15, 2025, 11:59 p.m. Eastern Time.
    Opportunity for Public Comment: During online registration, you may 
indicate if you wish to present during a public comment session, and 
which topic(s) you wish to address. We will do our best to accommodate 
requests to make public comments. Individuals and organizations with 
common interests are urged to consolidate or coordinate their 
presentations and request time for a joint presentation. All requests 
to make oral presentations during the meeting must be received via 
registration by September 15, 11:59 p.m. Eastern Time. Onsite 
registration for public comments on the day of the public meeting will 
not be provided. Following the close of registration, we will determine 
the amount of time allotted to each presenter and the approximate time 
each oral presentation is to begin, and will select and notify 
participants by September 17, 2025. If selected to present at the 
public comment session, any presentation materials must be emailed to 
<a href="/cdn-cgi/l/email-protection#e9aaadacbbb99b868e9b8884ac9f88859c889d808687a98f8d88c781819ac78e869f"><span class="__cf_email__" data-cfemail="400304051210322f2732212d0536212c352134292f2e002624216e2828336e272f36">[email&#160;protected]</span></a> by September 19, 11:59 p.m. Eastern 
Time. No commercial or promotional material will be permitted to be 
presented or distributed at the public meeting.
    Streaming Webcast of the Public Meeting: This public meeting will 
also be webcast to registered attendees. To view the webcast of this 
public meeting, please register at <a href="https://FDAPublicMeeting_PDUFAVII_BsUFAIII_HiringandRetention.eventbrite.com">https://FDAPublicMeeting_PDUFAVII_BsUFAIII_HiringandRetention.eventbrite.com</a> 
(see ``Registration''). Please provide complete contact information for 
each attendee, including, name, title, affiliation, and email.
    Transcripts: Please be advised that as soon as a transcript of the 
public meeting is available, it will be accessible at <a href="https://www.regulations.gov">https://www.regulations.gov</a>. It may be viewed at the Dockets Management Staff 
(see ADDRESSES). A link to the transcript will also be available on the 
internet at <a href="https://www.fda.gov/drugs/news-events-human-drugs/prescription-drug-user-fee-act-and-biosimilar-user-fee-amendments-hiring-and-retention-assessment">https://www.fda.gov/drugs/news-events-human-drugs/prescription-drug-user-fee-act-and-biosimilar-user-fee-amendments-hiring-and-retention-assessment</a>.
    Notice of this meeting is given pursuant to 21 CFR 10.65.

Grace R. Graham,
Deputy Commissioner for Policy, Legislation, and International Affairs.
[FR Doc. 2025-16245 Filed 8-22-25; 8:45 am]
BILLING CODE 4164-01-P


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