Notice2025-15157

Bulk Manufacturer of Controlled Substances Application: Cambrex Charles City

Primary source

Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.

Published
August 11, 2025

Issuing agencies

Justice DepartmentDrug Enforcement Administration

Abstract

Cambrex Charles City has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

Full Text

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<title>Federal Register, Volume 90 Issue 152 (Monday, August 11, 2025)</title>
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[Federal Register Volume 90, Number 152 (Monday, August 11, 2025)]
[Notices]
[Pages 38665-38666]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-15157]


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DEPARTMENT OF JUSTICE

Drug Enforcement Administration

[Docket No. DEA-1575]


Bulk Manufacturer of Controlled Substances Application: Cambrex 
Charles City

AGENCY: Drug Enforcement Administration, Justice.

ACTION: Notice of application.

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SUMMARY: Cambrex Charles City has applied to be registered as a bulk 
manufacturer of basic class(es) of controlled substance(s). Refer to 
SUPPLEMENTARY INFORMATION listed below for further drug information.

DATES: Registered bulk manufacturers of the affected basic class(es), 
and applicants, therefore, may submit electronic comments on or 
objections to the issuance of the proposed registration on or before 
October 10, 2025. Such persons may also file a written request for a 
hearing on the application on or before October 10, 2025.

ADDRESSES: The Drug Enforcement Administration requires that all 
comments be submitted electronically through the Federal eRulemaking 
Portal, which provides the ability to type short comments directly into 
the comment field on the web page or attach a file for lengthier 
comments. Please go to <a href="https://www.regulations.gov">https://www.regulations.gov</a> and follow the 
online instructions at that site for submitting comments. Upon 
submission of your comment, you will receive a Comment Tracking Number. 
Please be aware that submitted comments are not instantaneously 
available for public view on <a href="https://www.regulations.gov">https://www.regulations.gov</a>. If you have 
received a Comment Tracking Number, your comment has been successfully 
submitted and there is no need to resubmit the same comment.

SUPPLEMENTARY INFORMATION: In accordance with 21 CFR 1301.33(a), this 
is notice that on June 23, 2025, Cambrex Charles City, 1205 11th 
Street, Charles City, Iowa 50616-3466, applied to be registered as a 
bulk manufacturer of the following basic class(es) of controlled 
substance(s):

[[Page 38666]]



------------------------------------------------------------------------
        Controlled substance            Drug code          Schedule
------------------------------------------------------------------------
Gamma Hydroxybutyric Acid..........            2010  I
Tetrahydrocannabinols..............            7370  I
Amphetamine........................            1100  II
Lisdexamfetamine...................            1205  II
Methylphenidate....................            1724  II
ANPP (4-Anilino-N-phenethyl-4-                 8333  II
 piperidine).
Phenylacetone......................            8501  II
Codeine............................            9050  II
Oxycodone..........................            9143  II
Hydromorphone......................            9150  II
Hydrocodone........................            9193  II
Methadone..........................            9250  II
Morphine...........................            9300  II
Oripavine..........................            9330  II
Thebaine...........................            9333  II
Opium extracts.....................            9610  II
Opium fluid extract................            9620  II
Opium tincture.....................            9630  II
Opium, powdered....................            9639  II
Oxymorphone........................            9652  II
Noroxymorphone.....................            9668  II
Fentanyl...........................            9801  II
------------------------------------------------------------------------

    The company plans to manufacture the listed controlled substances 
in bulk for conversion to other controlled substances and sales to its 
customers for dosage form development, clinical trials and use in 
stability qualification studies. In reference to drug code 7370 
(Tetrahydrocannabinols), the company plans to bulk manufacture this 
drug as synthetic. No other activities for these drug codes are 
authorized for this registration.

Justin Wood,
Acting Deputy Assistant Administrator.
[FR Doc. 2025-15157 Filed 8-8-25; 8:45 am]
BILLING CODE P


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Indexed from Federal Register on August 11, 2025.

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