Notice2025-14653

Pesticide Product Registration; Receipt of Applications for New Active Ingredients (March-May 2025)

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Published
August 4, 2025

Issuing agencies

Environmental Protection Agency

Abstract

This document announces the Agency's receipt of and solicits comment on applications to register pesticide products containing active ingredients not included in any currently registered pesticide products. The Agency is providing this notice in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). EPA uses the month and year in the title to identify when the Agency compiled the applications identified in this notice of receipt. Unit II. of this document identifies certain applications received in 2023 and 2024 that are currently being evaluated by EPA, along with information about each application, including when it was received, who submitted the application, and the purpose of the application.

Full Text

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<title>Federal Register, Volume 90 Issue 147 (Monday, August 4, 2025)</title>
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[Federal Register Volume 90, Number 147 (Monday, August 4, 2025)]
[Notices]
[Pages 36433-36435]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-14653]


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ENVIRONMENTAL PROTECTION AGENCY

[EPA-HQ-OPP-2025-0024; FRL-12473-05-OCSPP]


Pesticide Product Registration; Receipt of Applications for New 
Active Ingredients (March-May 2025)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of receipt and request for comment.

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SUMMARY: This document announces the Agency's receipt of and solicits 
comment on applications to register pesticide products containing 
active ingredients not included in any currently registered pesticide 
products. The Agency is providing this notice in accordance with the 
Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). EPA uses 
the month and year in the title to identify when the Agency compiled 
the applications identified in this notice of receipt. Unit II. of this 
document identifies certain applications received in 2023 and 2024 that 
are currently being evaluated by EPA, along with information about each 
application, including when it was

[[Page 36434]]

received, who submitted the application, and the purpose of the 
application.

DATES: Comments must be received on or before September 3, 2025.

ADDRESSES: Submit your comments, identified by the docket 
identification (ID) number and the EPA File Symbol or the EPA 
Registration Number of interest as shown in Unit II. of this document, 
online at <a href="https://www.regulations.gov">https://www.regulations.gov</a>. Follow the online instructions 
for submitting comments. Do not submit electronically any information 
you consider to be Confidential Business Information (CBI) or other 
information whose disclosure is restricted by statute. Additional 
instructions on commenting and visiting the docket, along with more 
information about dockets generally, is available at <a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>.

FOR FURTHER INFORMATION CONTACT: Each application summary in Unit II. 
specifies a contact division. The appropriate division contacts are 
identified as follows:
    <bullet> BPPD (Biopesticides and Pollution Prevention Division) 
(Mail Code 7511M); Shannon Borges; main telephone number: (202) 566-
1400; or
    <bullet> RD (Registration Division) (Mail Code 7505T); Charles 
Smith; main telephone number: (202) 566-1030; email address: 
<a href="/cdn-cgi/l/email-protection#acfee8eafee2c3d8c5cfc9dfecc9dccd82cbc3da"><span class="__cf_email__" data-cfemail="b4e6f0f2e6fadbc0ddd7d1c7f4d1c4d59ad3dbc2">[email&#160;protected]</span></a>.

SUPPLEMENTARY INFORMATION:

I. Executive Summary

A. Does this action apply to me?

    This action provides information that is directed to the public in 
general.

B. What is the Agency's authority for taking this action?

    EPA is taking this action pursuant to section 3(c)(4) of the 
Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), 7 U.S.C. 
136a(c)(4), and 40 CFR 152.102.

C. What action is the Agency taking?

    EPA is hereby providing notice of receipt and an opportunity to 
comment on the applications identified in Unit II. of this document 
that seek to register pesticide products containing active ingredients 
not included in any currently registered pesticide products in 
accordance with FIFRA. Unit II. identifies and provides basic 
information about applications that are currently being evaluated by 
EPA. Notice of receipt of these applications does not imply a decision 
by the Agency on these applications. For actions being evaluated under 
EPA's public participation process for registration actions, there will 
be an additional opportunity for public comment on the proposed 
decisions. Please see EPA's public participation website for additional 
information on this process (<a href="https://www.epa.gov/pesticide-registration/public-participation-process-registration-actions">https://www.epa.gov/pesticide-registration/public-participation-process-registration-actions</a>).

D. What should I consider as I prepare my comments for EPA?

    1. Submitting CBI. Do not submit CBI to EPA through <a href="https://www.regulations.gov">https://www.regulations.gov</a> or email. If you wish to include CBI in your 
comment, please follow the applicable instructions at <a href="https://www.epa.gov/dockets/commenting-epa-dockets#rules">https://www.epa.gov/dockets/commenting-epa-dockets#rules</a> and clearly mark the 
information that you claim to be CBI. In addition to one complete 
version of the comment that includes CBI, a copy of the comment without 
CBI must be submitted for inclusion in the public docket. Information 
marked as CBI will not be disclosed except in accordance with 
procedures set forth in 40 CFR part 2.
    2. Tips for preparing your comments. When preparing and submitting 
your comments, see the commenting tips at <a href="https://www.epa.gov/dockets/commenting-epa-dockets">https://www.epa.gov/dockets/commenting-epa-dockets</a>.

II. Applications To Register New Active Ingredients

A. What information is being provided in this document?

    The following information is provided for the applications 
identified in Unit II.B.:
    <bullet> EPA File Symbol or Registration number(s);
    <bullet> EPA docket ID number for the application;
    <bullet> Name and address of the applicant;
    <bullet> Name of the active ingredient;
    <bullet> Product type;
    <bullet> Proposed uses;
    <bullet> Date received; and
    <bullet> Division to contact for that application.
    Additional information about the application may also be available 
in the docket identified for the application.

B. What applications are identified in this document?

    EPA received and is providing a public comment opportunity for the 
following applications:
    <bullet> EPA File Symbol: 5905-AAG. Docket ID number: EPA-HQ-OPP-
2024-0053. Applicant: Helena Agri-Enterprises, LLC., 225 Schilling 
Blvd., Suite 300, Collierville, TN 38017. Active ingredient: Cumyluron. 
Product type: Herbicide. Proposed use: Formulation of herbicide 
products intended for use on golf course turf grass. Received: 03/06/
2023. Contact: RD.
    <bullet> EPA File Symbol: 5905-AAU. Docket ID number: EPA-HQ-OPP-
2024-0053. Applicant: Helena Agri-Enterprises, LLC., 225 Schilling 
Blvd., Suite 300, Collierville, TN 38017. Active ingredient: Cumyluron. 
Product type: Herbicide. Proposed use: Golf course turf grass. 
Received: 03/06/2023. Contact: RD.
    <bullet> EPA File Symbol: 94430-R. Docket ID number: (EPA-HQ-OPP-
2024-0283). Applicant: WeedOUT, Ltd., c/o Ephi Gur Regulatory 
Consulting Inc. 2736 S. Evenfall Dr. Yuma, AZ 85635. Active ingredient: 
Herbicide, WDT-1, an irradiated pollen derived from non-glyphosate 
resistant varieties of Palmer Amaranth (Amaranthus palmeri) at 95%. 
Product type: WeedOUT Proposed use: Control of Palmer amaranth. 
Received: 12/20/2023. Contact: BPPD.
    <bullet> File Symbols: 102588-R, 102588-U, and 102588-G. Docket ID 
number: EPA-HQ-OPP-2025-0177. Applicant: Silvec Biologics Inc. 200 
Girard Street, Suite 200, Gaithersburg, MD 20877. Product names: 
Construct CTV-SoD2, Construct CTV-SoD2*, and Construct CTV-SoD2-1. 
Active ingredients: Citrus tristeza virus Expressing Spinach Defensin 
Protein 2, Citrus tristeza virus Expressing Spinach Defensin Protein 
2*, and Citrus tristeza virus Expressing Spinach Defensin Protein 2-1. 
Proposed use: Plant Protectant. Received: 01/08/2024. Contact: BPPD.
    <bullet> File Symbol: 103312-R. Docket ID number: EPA-HQ-OPP-2025-
0211. Applicant: Soil Culture Solutions, LLC (d/b/a Soilcea), 3802 
Spectrum Blvd., Suite 157, Tampa, FL 33612 Product name: CarriCea T1. 
Active ingredient: Loss of function gene ACD2 (Accelerated Cell Death 
2) and associated Cas9 protein and gRNA sequence, Loss of function gene 
Lls1 (Lethal Leaf Spot 1) and associated Cas9 protein and gRNA 
sequence, and Loss of function gene PLCP (Papain-Like Cysteine 
Protease) and associated Cas9 protein and gRNA sequence in CRISPR-
edited Carrizo rootstock. Proposed use: Plant-Incorporated Protectant. 
Received: 11/13/2024. Contact: BPPD.
    <bullet> File Symbol: 29964-GA. Docket ID number: EPA-HQ-OPP-2025-
0074. Applicant: Pioneer Hi-Bred International, Inc. 7300 NW 62nd 
Avenue, P.O. Box 1000, Johnston, IA 50131. Product name: COR23134 
Soybean. Active ingredients: Insecticide; Bacillus thuringiensis 
Cry1B.34.1 protein and the genetic material necessary (PHP90315 T-DNA) 
for its production, Bacillus thuringiensis Cry1B.61.1 protein and the 
genetic material necessary (PHP90315 T-DNA)

[[Page 36435]]

for its production, and Adiantum trapeziforme var. braziliense IPD083Cb 
protein and the genetic material necessary (PHP9035 T-DNA) for its 
production. Proposed classification/Use: Plant-Incorporated-Protectant 
(PIP) for use in soybean. Received: 2/1/2024. Contact: BPPD.
    <bullet> File Symbol: 524-AAO. Docket ID number: EPA-HQ-OPP-2025-
0297. Applicant: Bayer CropScience LP. Product name: MON 89151. Active 
ingredients: Insecticide--Bacillus thuringiensis Cry1Da_7 protein and 
the genetic material (Vector PV-GHIR529967) necessary for its 
production, Bacillus thuringiensis Cry1B.3 protein and the genetic 
material (Vector PV-GHIR529967) necessary for its production, and 
Paenibacillus spp. Vip3Cb1.1 protein and the genetic material (Vector 
PV-GHIR529967) necessary for its production. Proposed use: Plant-
Incorporated-Protectant (PIP) for use in cotton. Received: 12/10/2024. 
Contact: BPPD.
    <bullet> EPA Registration Number: 52991-UO. Docket ID number: EPA-
HQ-OPP-2025-0209. Applicant: Bedoukian Research, Inc., 6 Commerce 
Drive, Danbury, CT 06810. Product name: Bedoukian z-13-Octadecenal 
Technical Pheromone. Active ingredient: MP pheromone--z-13-Octadecenal 
at 96%. Proposed use: MP pheromone that acts as a behavior modifying 
biochemical pesticide which functions by mating disruption. Received: 
7/30/2024. Contact: BPPD.
    Authority: 7 U.S.C. 136 et seq.

    Dated: July 28, 2025.
Kimberly Smith,
Acting Director, Information Technology and Resources Management 
Division, Office of Program Support.
[FR Doc. 2025-14653 Filed 8-1-25; 8:45 am]
BILLING CODE 6560-50-P


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