Notice2025-14222

Agency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Notification Procedures for Statements of Dietary Supplements

Primary source

Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.

Published
July 29, 2025

Issuing agencies

Health and Human Services DepartmentFood and Drug Administration

Abstract

The Food and Drug Administration (FDA) is announcing that a proposed collection of information has been submitted to the Office of Management and Budget (OMB) for review and clearance under the Paperwork Reduction Act of 1995.

Full Text

<html>
<head>
<title>Federal Register, Volume 90 Issue 143 (Tuesday, July 29, 2025)</title>
</head>
<body><pre>
[Federal Register Volume 90, Number 143 (Tuesday, July 29, 2025)]
[Notices]
[Pages 35694-35695]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-14222]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Food and Drug Administration

[Docket No. FDA-2024-N-5234]


Agency Information Collection Activities; Submission for Office 
of Management and Budget Review; Comment Request; Notification 
Procedures for Statements of Dietary Supplements

AGENCY: Food and Drug Administration, HHS.

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: The Food and Drug Administration (FDA) is announcing that a 
proposed collection of information has been submitted to the Office of 
Management and Budget (OMB) for review and clearance under the 
Paperwork Reduction Act of 1995.

DATES: Submit written comments (including recommendations) on the 
collection of information by August 28, 2025.

ADDRESSES: To ensure that comments on the information collection are 
received, OMB recommends that written comments be submitted to <a href="https://www.reginfo.gov/public/do/PRAMain">https://www.reginfo.gov/public/do/PRAMain</a>. Find this particular information

[[Page 35695]]

collection by selecting ``Currently under Review--Open for Public 
Comments'' or by using the search function. The OMB control number for 
this information collection is 0910-0331. Also include the FDA docket 
number found in brackets in the heading of this document.

FOR FURTHER INFORMATION CONTACT: Domini Bean, Office of Operations, 
Food and Drug Administration, Three White Flint North, 10A-12M, 11601 
Landsdown St., North Bethesda, MD 20852, 301-796-5733, 
<a href="/cdn-cgi/l/email-protection#b6e6e4f7e5c2d7d0d0f6d0d2d798dedec598d1d9c0"><span class="__cf_email__" data-cfemail="f5a5a7b4a681949393b5939194db9d9d86db929a83">[email&#160;protected]</span></a>.

SUPPLEMENTARY INFORMATION: In compliance with 44 U.S.C. 3507, FDA has 
submitted the following proposed collection of information to OMB for 
review and clearance.

Food Labeling: Notification Procedures for Statements on Dietary 
Supplements--21 CFR 101.93

OMB Control Number 0910-0331--Extension

    Section 403(r)(6) of the FD&C Act (21 U.S.C. 343(r)(6)) and Sec.  
101.93 (21 CFR 101.93) require that, no later than 30 days after the 
first marketing, we be notified by the manufacturer, packer, or 
distributor of a dietary supplement that it is marketing a dietary 
supplement product that bears on its label or in its labeling a 
statement provided for in section 403(r)(6) of the FD&C Act. In 
accordance with these requirements, submissions must include: (1) the 
name and address of the manufacturer, packer, or distributor of the 
dietary supplement product; (2) the text of the statement that is being 
made; (3) the name of the dietary ingredient or supplement that is the 
subject of the statement; (4) the name of the dietary supplement 
(including the brand name); and (5) the signature of a responsible 
individual or the person who can certify the accuracy of the 
information presented, and who must certify that the information 
contained in the notice is complete and accurate, and that the 
notifying firm has substantiation that the statement is truthful and 
not misleading.
    Our electronic form (Form FDA 3955) allows respondents to the 
information collection to electronically submit notifications to FDA 
via the Food Applications Regulatory Management (FARM) system. Firms 
that prefer to submit a paper notification in an alternative format may 
opt to do so; however, Form FDA 3955 prompts respondents to include 
certain data elements in their structure/function claim notification 
(SFCN), as described in Sec.  101.93, in a standard electronic format 
and helps respondents organize their SFCN to include only the 
information needed for our review of the claim. Note that the SFCN, 
whether electronic or paper, is used for all claims made pursuant to 
section 403(r)(6) of the FD&C Act, including nutrient deficiency claims 
and general well-being claims in addition to structure/function claims. 
The electronic form, and any optional elements prepared as attachments 
to the form (e.g., label), can be submitted in electronic format via 
FARM. Submissions of SFCNs will continue to be allowed in paper format. 
We use this information to evaluate whether statements made for dietary 
ingredients or dietary supplements are permissible under section 
403(r)(6) of the FD&C Act. We also provide information on our website 
at <a href="https://www.fda.gov/food/information-industry-dietary-supplements/notifications-structurefunction-and-related-claims-dietary-supplement-labeling">https://www.fda.gov/food/information-industry-dietary-supplements/notifications-structurefunction-and-related-claims-dietary-supplement-labeling</a>, which may serve as a helpful resource to respondents.
    Description of Respondents: Respondents to this collection of 
information include manufacturers, packers, or distributors of dietary 
supplements that bear section 403(r)(6) of the FD&C Act statements on 
their labels or labeling.
    In the Federal Register of December 19, 2024 (89 FR 103835), we 
published a 60-day notice soliciting comment on the proposed collection 
of information. No comments were received.
    We estimate the burden of this collection of information as 
follows:

                                 Table 1--Estimated Annual Reporting Burden \1\
----------------------------------------------------------------------------------------------------------------
                                                               Number of       Total       Average
      21 CFR section; activity; Form No.        Number of    responses per     annual     burden per     Total
                                               respondents    respondent     responses     response      hours
----------------------------------------------------------------------------------------------------------------
101.93; Statements for Dietary Supplements;          3,690               1        3,690         0.75       2,768
 Form FDA 3955...............................                                                    (45
                                                                                            minutes)
----------------------------------------------------------------------------------------------------------------
\1\ There are no capital costs or operating and maintenance costs associated with this collection of
  information.

    Based on a review of the information collection since our last 
request for OMB approval, we have made no adjustments to our burden 
estimate. This estimate is based on our experience with this 
information collection and the number of notifications received in the 
past 3 years, which has remained constant.

    Dated: July 23, 2025.
Grace R. Graham,
Deputy Commissioner for Policy, Legislation, and International Affairs.
[FR Doc. 2025-14222 Filed 7-28-25; 8:45 am]
BILLING CODE 4164-01-P


</pre><script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script></body>
</html>
Indexed from Federal Register on July 29, 2025.

This is legal information, not legal advice. Laws vary by jurisdiction and change frequently. Always verify current law with official sources and consult a licensed attorney in your jurisdiction for advice on your specific situation.