Notice2025-06312

Mariste Pharmacy; Decision and Order

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Published
April 14, 2025

Issuing agencies

Justice DepartmentDrug Enforcement Administration

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<title>Federal Register, Volume 90 Issue 70 (Monday, April 14, 2025)</title>
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[Federal Register Volume 90, Number 70 (Monday, April 14, 2025)]
[Notices]
[Pages 15583-15587]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-06312]


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DEPARTMENT OF JUSTICE

Drug Enforcement Administration


Mariste Pharmacy; Decision and Order

    On May 20, 2024, the Drug Enforcement Administration (DEA or 
Government) issued an Order to Show Cause and Immediate Suspension of 
Registration (OSC/ISO) to Mariste Pharmacy (Registrant) of Richmond, 
Texas. Request for Final Agency Action (RFAA), Exhibit (RFAAX) 1, at 1. 
The OSC/ISO informed Registrant of the immediate suspension of its DEA 
Certificate of Registration, Control No. FM2279431, pursuant to 21 
U.S.C. 824(d), alleging that Registrant's continued registration 
constitutes `` `an imminent danger to the public health or safety.' '' 
Id. (quoting 21 U.S.C. 824(d)). The OSC/ISO also proposed the 
revocation of Registrant's registration, alleging that Registrant's 
continued registration is inconsistent with the public interest. Id. 
(citing 21 U.S.C. 823(g)(1), 824(a)(4)).
    Specifically, the OSC/ISO alleged that Registrant ``repeatedly 
filled Schedule II-V controlled substance prescriptions that contained 
red flags indicative of diversion and/or abuse, without appropriately 
addressing or resolving those red flags, . . . [in] violation of both 
federal and Texas law, including 21 CFR 1306.04(a) and 1306.06; and 
Texas Health & Safety Code Ann. Sec.  481.074(a).'' RFAAX 1, at 5. The 
OSC/ISO also alleged that Registrant ``had numerous record keeping 
violations and improperly stored controlled substances at a non-
registered location,'' in violation of 21 CFR 1304.11(a)-(c) and 
1304.21(a), (d). Id. at 5-6.
    The OSC/ISO notified Registrant of its right to file with DEA a 
written request for hearing within 30 days after the date of receipt of 
the OSC/ISO. Id. at 10-11 (citing 21 CFR 1301.43(a)). The OSC/ISO also 
notified Registrant that if it failed to file such a request, it would 
be deemed to have waived its right to a hearing and be in default. Id. 
(citing 21 CFR 1301.43(c), (d), (e)).

[[Page 15584]]

    To date, Registrant has not filed a hearing request with the OALJ 
Hearing Clerk,\1\ has not provided good cause for its failure to timely 
request a hearing, and has not filed a motion to excuse the default 
with the Office of the Administrator.\2\ 21 CFR 1301.43(c)(1). 
Accordingly, the Agency finds that Registrant is in default.
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    \1\ According to the Government's representations in the RFAA, 
Registrant filed a letter on June 19, 2024, in which it ``admitted, 
denied and/or further expounded on the allegations charged in the 
[OSC/ISO].'' RFAA, at 2. The Government represented that ``absent in 
this letter was a request for hearing'' and that ``DEA has not 
received any other correspondence from Registrant, or any attorney 
acting on her behalf, concerning the [OSC/ISO].'' Id.
    \2\ A party found in default may file a motion showing good 
cause to set aside the default no later than 30 days from the date 
of issuance of a final order. 21 CFR 1301.43(f)(3). Such motion must 
be filed with the Office of the Administrator, Drug Enforcement 
Administration, at <a href="/cdn-cgi/l/email-protection#5c38393d723d383833723d2828332e3239252f1c38393d723b332a"><span class="__cf_email__" data-cfemail="fa9e9f9bd49b9e9e95d49b8e8e9588949f8389ba9e9f9bd49d958c">[email&#160;protected]</span></a>.
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    ``A default, unless excused, shall be deemed to constitute a waiver 
of the [registrant's] right to a hearing and an admission of the 
factual allegations of the [OSC/ISO].'' 21 CFR 1301.43(e). Further, 
``[i]n the event that a registrant . . . is deemed to be in default . . 
. DEA may then file a request for final agency action with the 
Administrator, along with a record to support its request. In such 
circumstances, the Administrator may enter a default final order 
pursuant to [21 CFR] Sec.  1316.67.'' Id. Sec.  1301.43(f)(1). Here, 
the Government has requested final agency action based on Registrant's 
default pursuant to 21 CFR 1301.43(c), (f), 1301.46. RFAA, at 3; see 
also 21 CFR 1316.67.

I. Applicable Law

    As already discussed, the OSC/ISO alleges that Registrant violated 
multiple provisions of the Controlled Substances Act (CSA) and its 
implementing regulations. As the Supreme Court stated in Gonzales v. 
Raich, ``the main objectives of the CSA were to conquer drug abuse and 
to control the legitimate and illegitimate traffic in controlled 
substances. . . . To effectuate these goals, Congress devised a closed 
regulatory system making it unlawful to . . . dispense[ ] or possess 
any controlled substance except in a manner authorized by the CSA.'' 
545 U.S. 1, at 12-13 (2005). In maintaining this closed regulatory 
system, ``[t]he CSA and its implementing regulations set forth strict 
requirements regarding registration, . . . drug security, and 
recordkeeping.'' Id. at 14.
    The OSC/ISO's allegations concern the CSA's ``statutory and 
regulatory provisions . . . mandating . . . compliance with . . . 
security controls to guard against diversion, recordkeeping and 
reporting obligations, and prescription requirements'' and, therefore, 
go to the heart of the CSA's ``closed regulatory system'' specifically 
designed ``to conquer drug abuse and to control the legitimate and 
illegitimate traffic in controlled substances,'' and ``to prevent the 
diversion of drugs from legitimate to illicit channels.'' Id. at 12-14, 
27.

The Allegation That Registrant Filled Prescriptions Without Addressing 
or Resolving Red Flags of Abuse and/or Diversion

    According to the CSA's implementing regulations, a lawful 
prescription for controlled substances is one that is ``issued for a 
legitimate medical purpose by an individual practitioner acting in the 
usual course of his professional practice.'' 21 CFR 1306.04(a); see 
Gonzales v. Oregon, 546 U.S. 243, 274 (2006), United States v. Hayes, 
595 F.2d 258 (5th Cir. 1979), rehearing den., 598 F.2d 620 (5th Cir. 
1979), cert. denied, 444 U.S. 866 (1979); RFAAX 1, at 2. Although 
``[t]he responsibility for the proper prescribing and dispensing of 
controlled substances is upon the prescribing practitioner . . . a 
corresponding responsibility rests with the pharmacist who fills the 
prescription.'' 21 CFR 1306.04(a); United States v. Moore, 423 U.S. 
122, 136 n.12 (1975); United States v. Armstrong, 550 F.3d 382, 387 n.6 
(5th Cir. 2008); RFAAX 1, at 2. The corresponding responsibility 
requires ``pharmacists to identify and resolve suspicions that a 
prescription is illegitimate . . . before `knowingly filling such a 
purported prescription.' '' Trinity Pharmacy II, 83 FR 7304, 7331 
(2018); see also Suntree Pharmacy and Suntree Medical Equipment, LLC v. 
Drug Enf't Agency, 2022 WL 444,357, *6 (11th Cir.) (upholding the 
Agency's revocation order, which was ``[b]ased on [the] finding that 
Suntree violated its corresponding responsibility by filling 
prescriptions for controlled substances without resolving obvious red 
flags that the prescriptions lacked a legitimate medical purpose''); 
RFAAX 1, at 2. A respondent pharmacy ``fail[s] to comply with its 
corresponding responsibility not to fill prescriptions written for 
illegitimate purposes'' when it fails to ``tak[e] and document[ ] steps 
to resolve . . . red flags or refus[e] to fill prescriptions with 
unresolvable red flags.'' Pharmacy Doctors Enterprises Inc., d.b.a. 
Zion Clinic Pharmacy, 789 F. App'x 724, 731 (11th Cir. 2020). DEA 
regulations further require that a ``prescription for a controlled 
substance may only be filled by a pharmacist, acting in the usual 
course of his [or her] professional practice.'' 21 CFR 1306.06; RFAAX 
1, at 2.
    As for state law, Texas regulations have a similar requirement that 
pharmacists ensure that controlled substance prescriptions are ``issued 
for a legitimate medical purpose by a practitioner in the course of 
medical practice.'' 22 Tex. Admin. Code section 291.29(b); see also 
Tex. Health & Safety Code sections 481.074(a), 481.128(a)(1); RFAAX 1, 
at 3. Texas regulations also specify that ``[a] pharmacist may not 
dispense . . . a controlled substance . . . except under a valid 
prescription and in the course of professional practice.'' Tex. Health 
& Safety Code section 481.074(a); RFAAX 1, at 3.
    Texas regulations set forth various ``red flag factors'' that a 
pharmacist must consider in preventing the non-therapeutic dispensing 
of controlled substances. 22 Tex. Admin. Code section 291.29(f); RFAAX 
1, at 4. Pharmacists should consider these red flags ``by evaluating 
the totality of the circumstances rather than any single factor.'' 22 
Tex. Admin. Code section 291.29(f). These red flags include instances 
where: (f)(11) multiple persons with the same address present 
substantially similar controlled substance prescriptions from the same 
practitioner; and (f)(12) persons consistently pay for controlled 
substance prescriptions with cash or cash equivalents more often than 
through insurance. RFAAX 1, at 4. Texas regulations also identify ``the 
geographical distance between the practitioner and the patient'' as a 
``reason[ ] to suspect that a prescription may have been authorized in 
the absence of a valid patient-practitioner relationship or in 
violation of the practitioner's standard of practice.'' 22 Tex. Admin. 
Code section 291.29(c)(4); RFAAX 1, at 8. Further, under Texas 
regulations, ``[a] pharmacist shall not dispense a prescription drug if 
the pharmacist knows or should know the prescription drug order is 
fraudulent or forged.'' 22 Tex. Admin. Code section 291.29(f). Texas 
regulations further require pharmacists to ``review the patient's 
medication record'' to ensure the ``therapeutic appropriateness'' of 
the prescription, and if a problem is observed, the pharmacist must 
``avoid or resolve the problem including consultation with the 
prescribing practitioner.'' 22 Tex. Admin. Code sections 
291.33(c)(2)(A)(i)-(ii); RFAAX 1, at 3. A pharmacist must resolve all 
problems raised by a prescription before dispensing it and must 
document how the problem was resolved. 22 Tex. Admin. Code section 
291.33(c)(2)(A)(iv);

[[Page 15585]]

see also id. section 291.33(c)(2)(C) (outlining the information that 
such documentation must include); RFAAX 1, at 3-4.

The Allegation That Registrant Failed to Adequately Maintain Complete 
and Accurate Records

    Federal law also imposes recordkeeping and security requirements on 
pharmacies. For example, the CSA requires pharmacies to keep accurate 
and timely records of inventory and dispensing. 21 CFR 1304.11(a)-(c); 
RFAAX 1, at 5. This includes conducting and maintaining an ``initial 
inventory . . . of all stocks of controlled substances on hand on the 
date [the pharmacy] first engages in the . . . dispensing of controlled 
substances,'' as well as conducting and maintaining a ``biennial 
inventory . . . of all stocks of controlled substances on hand.'' 21 
CFR 1304.11(a)-(c); RFAAX 1, at 5. Pharmacies must retain these 
inventories ``for at least 2 years from the date of such inventory or 
records, for inspection and copying.'' 21 CFR 1304.04; RFAAX 1, at 3. 
The CSA also requires pharmacies to ``maintain, on a current basis, a 
complete and accurate record of each substance . . . received,'' and 
the pharmacy must ``record[ ] . . . the date on which the controlled 
substances are actually received.'' 21 CFR 1304.21(a); RFAAX 1, at 3.

II. Findings of Fact

The Allegation That Registrant Filled Prescriptions Without Addressing 
or Resolving Red Flags of Abuse and/or Diversion

    The Agency finds that, in light of Registrant's default, the 
factual allegations in the OSC/ISO are deemed admitted.\3\ 21 CFR 
1301.43(e). Accordingly, Registrant is deemed to have admitted and the 
Agency finds that Registrant repeatedly dispensed prescriptions in 
violation of the minimum practice standards that govern pharmacy 
practice in Texas. RFAAX 1, at 6-9. Specifically, from at least 
February 2021 through March 2024, Registrant repeatedly filled 
controlled substance prescriptions that contained multiple red flags of 
abuse and/or diversion without addressing or resolving the red flags. 
Id.
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    \3\ The Agency need not adjudicate the criminal violations 
alleged in the instant OSC/ISO. Ruan v. United States, 142 S. Ct. 
2,370 (2022) (decided in the context of criminal proceedings).
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Cash Payments

    As discussed above, see supra Section I, Texas regulations identify 
the following prescribing pattern as a red flag factor: ``[P]ersons 
consistently pay for controlled substance prescriptions with cash or 
cash equivalents more often than through insurance.'' 22 Tex. Admin. 
Code section 291.29(f)(12); RFAAX 1, at 6. Registrant is deemed to have 
admitted that it failed to identify and resolve the red flag of cash 
payments. RFAAX 1, at 6. Specifically, between February 2021 and March 
2024, Registrant filled 1,273 prescriptions for oxycodone 30 mg (a 
Schedule II opioid), and approximately 1,272 of those prescriptions 
were paid for in cash or cash equivalents. Id.
    Accordingly, the Agency finds substantial record evidence that 
Registrant filled approximately 1,272 controlled substance 
prescriptions without first resolving the red flag arising from cash 
payments.

Shared Addresses

    Texas regulations identify the following prescribing pattern as a 
red flag factor: ``[M]ultiple persons with the same address present 
substantially similar controlled substance prescriptions from the same 
practitioner.'' 22 Tex. Admin. Code section 291.29(f)(11); RFAAX 1, at 
7. Registrant is deemed to have admitted that it failed to identify and 
resolve the red flag of multiple persons with the same address 
presenting the same prescriptions from the same practitioner. RFAAX 1, 
at 7-8. Specifically, between February 2021 and August 2023, Registrant 
filled controlled substance prescriptions for two groups of patients 
who shared the same address \4\ and presented prescriptions for the 
same controlled substance (oxycodone 30 mg) from the same practitioner 
(Dr. V.M.). Id. at 8.\5\
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    \4\ These patients included T.C., R.L.C., and T.G., who shared 
the same address, and H.E., Z.J., and Di.P. who shared the same 
address.
    \5\ The OSC/ISO contains additional allegations of patients with 
a shared address presenting prescriptions for the same controlled 
substance from the same prescriber. RFAAX 1, at 7-8. However, each 
of these allegations identifies multiple prescribers and multiple 
patients, and it is unclear which prescribers issued prescriptions 
to which patients. Thus, it is not clear from substantial record 
evidence or an admission that patients sharing the same address were 
receiving the same controlled substance from the same prescriber. 
Accordingly, the remaining allegations regarding the red flag of 
pattern prescribing are not sustained. The Agency finds that the 
founded allegations in this decision are more than sufficient to 
support the Government's requested sanction of revocation under 
these circumstances.
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    Accordingly, the Agency finds substantial record evidence that 
Registrant filled numerous controlled substance prescriptions without 
first resolving the red flag of shared addresses.

Long Distances

    Texas regulations identify ``the geographical distance between the 
practitioner and the patient'' as a ``reason[ ] to suspect that a 
prescription may have been authorized in the absence of a valid 
patient-practitioner relationship or in violation of the practitioner's 
standard of practice.'' 22 Tex. Admin. Code section 291.29(c)(4); RFAAX 
1, at 8. Registrant is deemed to have admitted that it repeatedly 
filled prescriptions without identifying and resolving the red flag of 
patients traveling long distances to obtain controlled substance 
prescriptions. RFAAX 1, at 8-9. Specifically, Registrant is deemed to 
have admitted that between February 2021 and June 2022, it filled 
numerous prescriptions for four individuals (A.S.W., De.D.G., J.G., and 
C.R.) who traveled more than 45 miles one way to obtain their 
controlled substance prescriptions, and for three individuals (D.A., 
F.G., and R.D.) who traveled more than 70 miles one way to obtain their 
prescriptions. Id. at 9.
    Accordingly, the Agency finds substantial record evidence that 
Registrant filled numerous controlled substance prescriptions without 
first resolving the red flag arising from long distances traveled.\6\
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    \6\ The OSC/ISO additionally alleged that Registrant filled 
numerous prescriptions for controlled substances for certain 
patients that were issued by practitioners engaging in ``pattern 
prescribing.'' RFAAX 1, 6-7. For example, the OSC/ISO alleges, and 
it is therefore admitted, that ``Between February 1, 2021, and until 
at least March 6, 2024, the Pharmacy filled prescriptions for 
Patients V.R., B.A.C., R.B., V.S., R.J.H., B.R., L.K., K.K., C.D.G., 
R.F., H.W, and De.G. who presented prescriptions for oxycodone 30 mg 
from multiple practitioners, in violation of Texas law.'' Id. at 7. 
The OSC/ISO implies that this conduct violates 22 Texas 
Administrative Code section 291.29(f)(10), which identifies as a 
potential red flag factor that ``the Texas Prescription Monitoring 
Program indicates the person presenting the prescriptions is 
obtaining similar drugs from multiple practitioners.'' It is not 
clear from substantial record evidence or an admission whether each 
of the 12 patients listed was receiving prescriptions from multiple 
practitioners, or if there were multiple prescribers who issued 
prescriptions to this group of 12 patients. Accordingly, this 
allegation is not sustained.
    The OSC/ISO also alleged, and it is therefore admitted, that 
``Between February 1, 2021, and until at least March 6, 2024, the 
Pharmacy filled oxycodone 30 mg prescriptions for Patients B.A.C., 
D.Y., K.M.K., Z.J., S.D.W., R.B., V.R., and H.W. which were for only 
the highest strength and in high quantities, in violation of Texas 
law.'' RFAAX 1, at 6-7. The OSC/ISO implies that this conduct 
violates 22 Texas Administrative Code section 291.29(f)(5), which 
identifies as a potential red flag factor that ``prescriptions for 
controlled substances are commonly for the highest strength of the 
drug and/or for large quantities (e.g., monthly supply), indicating 
a lack of individual drug therapy in prescriptions issued by the 
practitioner.'' Id. at 7. It is not clear from substantial record 
evidence or an admission that any of these patients shared the same 
practitioner. Accordingly, this allegation is not sustained. The 
Agency finds that the founded allegations in this decision are more 
than sufficient to support the Government's requested sanction of 
revocation under these circumstances.

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[[Page 15586]]

Expert Review

    DEA retained an independent pharmacy expert who concluded that the 
above prescription data presented multiple red flags that were highly 
indicative of abuse and diversion. Id. The expert further concluded, 
and Registrant admits that, ``[t]hese red flags were not adequately 
resolved by a pharmacist acting in the usual course of professional 
practice prior to dispensing, and therefore, each prescription was 
filled outside the standard of care of pharmacy practice in Texas.'' 
Id. Registrant further admitted that none of the above-referenced 
controlled substance prescriptions was filled for a legitimate medical 
purpose. Id.
    Accordingly, the Agency finds substantial record evidence that 
Registrant dispensed the above-referenced prescriptions without first 
resolving the red flags of cash payments, long distances, and/or shared 
addresses, and that Registrant's dispensing of these prescriptions was 
outside the usual course of professional practice. Additionally, the 
Agency finds substantial record evidence that none of the above-
referenced controlled substance prescriptions was filled for a 
legitimate medical purpose.

The Allegation That Registrant Failed to Adequately Maintain Complete 
and Accurate Records

    Registrant is deemed to have admitted that it failed to adequately 
maintain an initial inventory and a biennial inventory, which prevented 
DEA from conducting an audit. RFAAX 1, at 5. Accordingly, the Agency 
finds substantial evidence that Registrant failed to adequately 
maintain an initial and biennial inventory.
    Further, Registrant is deemed to have admitted that between 
February 2021 and February 2023, it failed to adequately maintain 
complete and accurate continuing records regarding its inventory of 
controlled substances. Id. at 6. Specifically, Registrant admits that 
it failed to adequately maintain a record of the receipt of controlled 
substances, and that it was unable to provide DEA with even the most 
basic required documentation concerning its on-hand controlled 
substance inventory. Id.
    Accordingly, the Agency finds substantial evidence that Registrant 
failed to maintain a complete and accurate record of each substance 
received.\7\
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    \7\ The OSC/ISO additionally alleged, and it is therefore 
admitted, that ``on or about February 14, 2023, [Registrant's] owner 
was discovered to be storing large amounts of controlled substances 
at a personal residence that is not a registered location,'' and 
that ``DEA discovered that the controlled substances were being 
transported back and forth between the registered pharmacy location 
and the unregistered personal residence.'' RFAAX 1, at 6. The OSC/
ISO implies that this conduct violates 21 CFR 1301.75(b), which 
states that ``Controlled substances listed in Schedules II, III, IV, 
and V shall be stored in a securely locked, substantially 
constructed cabinet.'' It is not clear from substantial record 
evidence or an admission that Registrant's transporting of 
controlled substances means that Registrant was not storing 
controlled substances in a ``securely locked, substantially 
constructed cabinet.'' Further, 21 CFR 1301.75(b) does not state 
that controlled substances must be stored at a ``registered 
location,'' and the OSC/ISO does not identify additional statutory 
support for this requirement. Accordingly, this allegation regarding 
the failure to adequately store controlled substances is not 
sustained. The Agency finds that the founded allegations in this 
decision are more than sufficient to support the Government's 
requested sanction of revocation under these circumstances.
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I. Discussion

A. The Five Public Interest Factors

    Under Section 304 of the CSA, ``[a] registration . . . to . . . 
distribute[ ] or dispense a controlled substance . . . may be suspended 
or revoked by the Attorney General upon a finding that the registrant . 
. . has committed such acts as would render his registration under . . 
. [21 U.S.C. 823] inconsistent with the public interest as determined 
by such section.'' 21 U.S.C. 824(a)(4). In the case of a 
``practitioner,'' which is defined in 21 U.S.C. 802(21) to include a 
``pharmacy,'' Congress directed the Attorney General to consider five 
factors in making the public interest determination. 21 U.S.C. 
823(g)(1)(A-E).\8\ The five factors are considered in the disjunctive. 
Gonzales v. Oregon, 546 U.S. at 292-93 (2006) (Scalia, J., dissenting) 
(``It is well established that these factors are to be considered in 
the disjunctive,'' citing In re Arora, 60 FR 4447, 4448 (1995)); Robert 
A. Leslie, M.D., 68 FR 15227, 15230 (2003). Each factor is weighed on a 
case-by-case basis. Morall v. Drug Enf't Admin., 412 F.3d 165, 173-74 
(D.C. Cir. 2005). Any one factor, or combination of factors, may be 
decisive. Penick Corp. v. Drug Enf't Admin., 491 F.3d 483, 490 (D.C. 
Cir. 2007); Morall, 412 F.3d. at n.2; David H. Gillis, M.D., 58 FR 
37507, 37508 (1993).
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    \8\ The five factors of 21 U.S.C. 823(g)(1)(A-E) are: (a) The 
recommendation of the appropriate State licensing board or 
professional disciplinary authority. (b) The applicant's experience 
in dispensing, or conducting research with respect to controlled 
substances. (c) The applicant's conviction record under Federal or 
State laws relating to the manufacture, distribution, or dispensing 
of controlled substances. (d) Compliance with applicable State, 
Federal, or local laws relating to controlled substances. (e) Such 
other conduct which may threaten the public health and safety.
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    In this matter, while all of the 21 U.S.C. 823(g)(1) factors have 
been considered, the Agency finds that the Government's evidence in 
support of its prima facie case is confined to Factors B and D. See 
RFAAX 1, at 6. Moreover, the Government has the burden of proof in this 
proceeding. 21 CFR 1301.44.
    Here, the Agency finds that the Government's evidence satisfies its 
prima facie burden of showing that Registrant's continued registration 
would be ``inconsistent with the public interest.'' 21 U.S.C. 
823(g)(1).

B. Allegation That Registrant's Registration Is Inconsistent With the 
Public Interest

Factors B and/or D--Registrant's Experience in Dispensing Controlled 
Substances and Compliance With Applicable Laws Related to Controlled 
Substances
    Evidence is considered under Public Interest Factors B and D when 
it reflects compliance or non-compliance with federal and local laws 
related to controlled substances and experience dispensing controlled 
substances. 21 U.S.C. 823(g)(1)(B) and (D); see also Kareem Hubbard, 
M.D., 87 FR 21156, 21162 (2022).
    Here, as found above, Registrant is deemed to have admitted and the 
Agency finds that Registrant repeatedly filled prescriptions for 
controlled substances that contained red flags of abuse and/or 
diversion without addressing or resolving those red flags. RFAAX 1, at 
5-9. Registrant has further admitted and the Agency finds that none of 
the above-referenced controlled substance prescriptions were filled for 
a legitimate medical purpose in the usual course of professional 
practice. Id. As such, the Agency finds substantial record evidence 
that Registrant violated 21 CFR 1306.04, 1306.06, Texas Health & Safety 
Code section 481.074, and 22 Texas Administrative Code sections 291.29, 
291.33.
    Additionally, as found above, Registrant is deemed to have admitted 
and the Agency finds that Registrant failed to maintain an initial and 
biennial inventory. As such, the Agency finds substantial record 
evidence that Registrant violated 21 CFR 1304.11(a)-(c) and 1304.04.\9\ 
Finally, Registrant has

[[Page 15587]]

admitted and the Agency finds that it failed to maintain complete and 
accurate records of each controlled substance received. As such, the 
Agency finds substantial record evidence that Registrant violated 21 
CFR 1304.21(a).
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    \9\ The OSC/ISO alleges that Registrant's failure to maintain an 
initial and biennial inventory and its failure to maintain records 
of receipt of controlled substances also violated 22 Texas 
Administrative Code section 291.75(a)(l), (c)(4)-(5). RFAAX 1, at 5. 
However, the OSC/ISO does not contain sufficient factual or legal 
analysis to enable to Agency to assess the relevance or 
applicability of these statutes. Section (a)(1)(A) pertains to 
institutional pharmacies, and the OSC/ISO does not allege that 
Registrant is an institutional pharmacy. Section (c)(4) outlines 
requirements for patient records of Schedule II controlled 
substances to be maintained separately from patient records of 
controlled substances in other schedules, and it outlines additional 
requirements related to distribution records and institutional 
pharmacies. Finally, Section (c)(5) pertains to floor stock records.
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    The Agency further finds that Factors B and D weigh in favor of 
denial of Registrant's application and that Registrant's registration 
would be inconsistent with the public interest in balancing the factors 
of 21 U.S.C. 823(g)(1). Accordingly, the Agency finds that the 
Government established a prima facie case, that Registrant did not 
rebut that prima facie case, and that there is substantial record 
evidence supporting the revocation of Registrant's registration. 21 
U.S.C. 823(g)(1).

II. Sanction

    Where, as here, the Government has met its prima facie burden of 
showing that Registrant's registration is inconsistent with the public 
interest due to its numerous violations pertaining to controlled 
substances, the burden shifts to Registrant to show why it can be 
entrusted with a registration. Morall, 412 F.3d. at 174; Jones Total 
Health Care Pharmacy, 881 F.3d 823, 830 (11th Cir. 2018); Garrett 
Howard Smith, M.D., 83 FR 18882 (2018). The issue of trust is 
necessarily a fact-dependent determination based on the circumstances 
presented by the individual registrant. Jeffrey Stein, M.D., 84 FR 
46968, 46972 (2019); see also Jones Total Health Care Pharmacy, 881 
F.3d at 833. Moreover, as past performance is the best predictor of 
future performance, DEA Administrators have required that a registrant 
who has committed acts inconsistent with the public interest must 
accept responsibility for those acts and demonstrate that it will not 
engage in future misconduct. Jones Total Health Care Pharmacy, 881 F.3d 
at 833. A registrant's acceptance of responsibility must be 
unequivocal. Id. at 830-31. In addition, a registrant's candor during 
the investigation and hearing has been an important factor in 
determining acceptance of responsibility and the appropriate sanction. 
Id. Further, DEA Administrators have found that the egregiousness and 
extent of the misconduct are significant factors in determining the 
appropriate sanction. Id. at 834 and n.4. DEA Administrators have also 
considered the need to deter similar acts by the specific registrant 
and by the community of registrants. Jeffrey Stein, M.D., 84 FR 46972-
73.
    Here, Registrant did not timely or properly request a hearing and 
was deemed to be in default. 21 CFR 1301.43(c)(1), (e), (f)(1); RFAA, 
at 1-9. To date, Registrant has not filed a motion with the Office of 
the Administrator to excuse the default. 21 CFR 1301.43(c)(1). 
Registrant has thus failed to answer the allegations contained in the 
OSC and has not otherwise availed itself of the opportunity to refute 
the Government's case. As such, Registrant has made no representations 
as to its future compliance with the CSA nor made any demonstration 
that it can be entrusted with registration. Moreover, the evidence 
presented by the Government shows that Registrant violated the CSA, 
further indicating that Registrant cannot be entrusted.
    Accordingly, the Agency will order the revocation of Registrant's 
application.

Order

    Pursuant to 28 CFR 0.100(b) and the authority vested in me by 21 
U.S.C. 824(a), I hereby revoke DEA Certificate of Registration No. 
FM2279431 issued to Mariste Pharmacy. Further, pursuant to 28 CFR 
0.100(b) and the authority vested in me by 21 U.S.C. 823(g)(1), I 
hereby deny any pending applications of Mariste Pharmacy to renew or 
modify this registration, as well as any other pending application of 
Mariste Pharmacy for additional registration in Texas. This Order is 
effective May 14, 2025.

Signing Authority

    This document of the Drug Enforcement Administration was signed on 
April 8, 2025, by Acting Administrator Derek Maltz. That document with 
the original signature and date is maintained by DEA. For 
administrative purposes only, and in compliance with requirements of 
the Office of the Federal Register, the undersigned DEA Federal 
Register Liaison Officer has been authorized to sign and submit the 
document in electronic format for publication, as an official document 
of DEA. This administrative process in no way alters the legal effect 
of this document upon publication in the Federal Register.

Heather Achbach,
Federal Register Liaison Officer, Drug Enforcement Administration.
[FR Doc. 2025-06312 Filed 4-11-25; 8:45 am]
BILLING CODE 4410-09-P


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Indexed from Federal Register on April 14, 2025.

This is legal information, not legal advice. Laws vary by jurisdiction and change frequently. Always verify current law with official sources and consult a licensed attorney in your jurisdiction for advice on your specific situation.