Rule2025-03872
Metamitron; Pesticide Tolerances
Primary source
Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.
Published
March 11, 2025
Effective
March 11, 2025
Issuing agencies
Environmental Protection Agency
Abstract
This regulation establishes tolerances for residues of metamitron in or on apple and pear. ADAMA AGAN c/o Makhteshim Agan of North America, Inc. (d/b/a ADAMA) requested these tolerances under the Federal Food, Drug, and Cosmetic Act (FFDCA).
Full Text
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<title>Federal Register, Volume 90 Issue 46 (Tuesday, March 11, 2025)</title>
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[Federal Register Volume 90, Number 46 (Tuesday, March 11, 2025)]
[Rules and Regulations]
[Pages 11670-11674]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2025-03872]
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ENVIRONMENTAL PROTECTION AGENCY
40 CFR Part 180
[EPA-HQ-OPP-2022-0575; FRL-12591-01-OCSPP]
Metamitron; Pesticide Tolerances
AGENCY: Environmental Protection Agency (EPA).
ACTION: Final rule.
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SUMMARY: This regulation establishes tolerances for residues of
metamitron in or on apple and pear. ADAMA AGAN c/o Makhteshim Agan of
North America, Inc. (d/b/a ADAMA) requested these tolerances under the
Federal Food, Drug, and Cosmetic Act (FFDCA).
DATES: This regulation is effective March 11, 2025. Objections and
requests for hearings must be received on or before May 12, 2025 and
must be filed in accordance with the instructions provided in 40 CFR
part 178 (see also Unit I.C. of the SUPPLEMENTARY INFORMATION).
ADDRESSES: The docket for this action, identified by docket
identification (ID) number EPA-HQ-OPP-2022-0575, is available online at
<a href="https://www.regulations.gov">https://www.regulations.gov</a>. Additional information about dockets
generally, along with instructions for visiting the docket in-person,
is available at <a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>.
FOR FURTHER INFORMATION CONTACT: Charles Smith, Director, Registration
Division (7505T), Office of Pesticide Programs, Environmental
Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-
0001; main telephone number: (202) 566-1030; email address:
<a href="/cdn-cgi/l/email-protection#f9abbdbfabb7968d909a9c8ab99c8998d79e968f"><span class="__cf_email__" data-cfemail="40120406120e2f3429232533002530216e272f36">[email protected]</span></a>.
SUPPLEMENTARY INFORMATION:
I. Executive Summary
A. Does this action apply to me?
You may be potentially affected by this action if you are an
agricultural producer, food manufacturer, or pesticide manufacturer.
The following list of North American Industrial Classification System
(NAICS) codes is not intended to be exhaustive, but rather provides a
guide to help readers determine whether this document applies to them.
Potentially affected entities may include:
<bullet> Crop production (NAICS code 111).
<bullet> Animal production (NAICS code 112).
<bullet> Food manufacturing (NAICS code 311).
<bullet> Pesticide manufacturing (NAICS code 32532).
If you have any questions regarding the applicability of this
proposed action to a particular entity, consult the person listed under
FOR FURTHER INFORMATION CONTACT.
B. What is EPA's authority for taking this action?
This tolerance action is issued pursuant to section 408 of the
Federal Food, Drug, and Cosmetic Act (FFDCA), 21 U.S.C. 346a et seq.,
and EPA regulations in 40 CFR part 180. FFDCA section 408(b)(2)(A)(i)
allows EPA to establish a tolerance (the legal limit for a pesticide
chemical residue in or on a food) only if EPA determines that the
[[Page 11671]]
tolerance is ``safe.'' Section 408(b)(2)(A)(ii) of FFDCA defines
``safe'' to mean that ``there is a reasonable certainty that no harm
will result from aggregate exposure to the pesticide chemical residue,
including all anticipated dietary exposures and all other exposures for
which there is reliable information.'' This includes exposure through
drinking water and in residential settings but does not include
occupational exposure. Section 408(b)(2)(C) of FFDCA requires EPA to
give special consideration to exposure of infants and children to the
pesticide chemical residue in establishing a tolerance and to ``ensure
that there is a reasonable certainty that no harm will result to
infants and children from aggregate exposure to the pesticide chemical
residue. . . .''
C. How can I file an objection or hearing request?
Under FFDCA section 408(g), 21 U.S.C. 346a(g), any person may file
an objection to any aspect of this regulation and may also request a
hearing on those objections. If you fail to file an objection to the
final rule within the time period specified in the final rule, you will
have waived the right to raise any issues resolved in the final rule.
You must file your objection or request a hearing on this regulation in
accordance with the instructions provided in 40 CFR part 178. To ensure
proper receipt by EPA, you must identify docket ID number EPA-HQ-OPP-
2022-0575 in the subject line on the first page of your submission. All
objections and requests for a hearing must be in writing and must be
received by the Hearing Clerk on or before May 12, 2025.
The EPA's Office of Administrative Law Judges (OALJ), in which the
Hearing Clerk is housed, urges parties to file and serve documents by
electronic means only, notwithstanding any other particular
requirements set forth in other procedural rules governing those
proceedings. See ``Revised Order Urging Electronic Filing and
Service,'' dated June 22, 2023, which can be found at <a href="https://www.epa.gov/system/files/documents/2023-06/2023-06-22%20-%20revised%20order%20urging%20electronic%20filing%20and%20service.pdf">https://www.epa.gov/system/files/documents/2023-06/2023-06-22%20-%20revised%20order%20urging%20electronic%20filing%20and%20service.pdf</a>.
Although the EPA's regulations require submission via U.S. Mail or hand
delivery, the EPA intends to treat submissions filed via electronic
means as properly filed submissions; therefore, the EPA believes the
preference for submission via electronic means will not be prejudicial.
When submitting documents to the OALJ electronically, a person should
utilize the OALJ e-filing system at <a href="https://yosemite.epa.gov/oa/eab/eab-alj_upload.nsf">https://yosemite.epa.gov/oa/eab/eab-alj_upload.nsf</a>.
II. Summary of Petitioned-For Tolerance
In the Federal Register of August 30, 2022 (87 FR 52868) (FRL-9410-
04-OCSPP), EPA issued a document pursuant to FFDCA section 408(d)(3),
21 U.S.C. 346a(d)(3), announcing the filing of a pesticide petition (PP
1F8977) by ADAMA AGAN c/o Makhteshim Agan of North America, Inc. (d/b/a
ADAMA), 8601 Six Forks Road, Suite 300, Raleigh, NC 27615. The petition
requested that 40 CFR part 180 be amended by establishing tolerances
for residues of the herbicide metamitron, including its metabolites and
degradates, in or on pome fruit (crop group 11-10) at 0.01 parts per
million (ppm). That document referenced a summary of the petition
prepared by ADAMA, the registrant, which is available in the docket.
There were no comments received in response to the request for comments
on the petition that published on August 30, 2022.
On August 5, 2024, following conversations with EPA, ADAMA informed
the Agency that they wish to modify their petition to instead establish
tolerances on apple and pear at 0.01 ppm. Because the tolerance
petition originally published for public comment contains both of these
commodities in crop group 11-10, EPA did not request additional comment
after that change.
III. Aggregate Risk Assessment and Determination of Safety
Consistent with FFDCA section 408(b)(2)(D), and the factors
specified therein, EPA has reviewed the available scientific data and
other relevant information in support of this action. EPA has
sufficient data to assess the hazards of and to make a determination on
aggregate exposure for metamitron including exposure resulting from the
tolerances established by this action. EPA's assessment of exposures
and risks associated with metamitron follows.
A. Toxicological Profile
EPA has evaluated the available toxicity data and considered its
validity, completeness, and reliability as well as the relationship of
the results of the studies to human risk. EPA has also considered
available information concerning the variability of the sensitivities
of major identifiable subgroups of consumers, including infants and
children.
The liver is the main target organ in both subchronic and chronic
toxicity studies in all three species tested (rat, mouse, dog) with
gall bladder toxicity only observed in the dog. Neurotoxicity (clinical
signs and functional observational battery (FOB) findings) was also
observed following an acute exposure (single dose) in both mice and
rats. In addition to target organ toxicity, decreased body weights were
observed in rats and dogs. Across all three species tested, the
severity of the adverse liver and body weight effects progressed across
time and dose, with the rat and dog being more sensitive (i.e., effects
were seen at lower doses) as compared to the mouse when allometric
scaling is not considered. Females tended to be slightly more sensitive
as compared to males and this sex difference may be due to the longer
half-life and slower decline of metamitron in vivo in females.
Metamitron is classified as ``Not Likely to Be Carcinogenic to
Humans'' based on a lack of treatment-related tumors in acceptable rat
and mouse carcinogenicity studies and low concern for mutagenic
potential.
Specific information on the studies received and the nature of the
adverse effects caused by metamitron as well as the no-observed-
adverse-effect-level (NOAEL) and the lowest-observed-adverse-effect-
level (LOAEL) from the toxicity studies can be found on pages 12-20 in
the document ``Metamitron. Human Health Risk Assessment for First Food
Use Petition for the Establishment of Permanent Tolerances and
Registration for Uses on Apple and Pear. New Active Ingredient''
hereinafter referred to as ``Metamitron Human Health Risk Assessment''
that is available in docket ID number EPA-HQ-OPP-2022-0575.
B. Toxicological Points of Departure/Levels of Concern
Once a pesticide's toxicological profile is determined, EPA
identifies toxicological points of departure (POD) and levels of
concern to use in evaluating the risk posed by human exposure to the
pesticide. For hazards that have a threshold below which there is no
appreciable risk, the toxicological POD is used as the basis for
derivation of reference values for risk assessment. PODs are developed
based on a careful analysis of the doses in each toxicological study to
determine the dose at which no adverse effects are observed (the NOAEL)
and the lowest dose at which adverse effects of concern are identified
(the LOAEL). Uncertainty/safety factors are used in conjunction with
the POD to calculate a safe exposure level--generally referred to as a
population-adjusted dose (PAD) or a reference dose (RfD)--and a safe
margin
[[Page 11672]]
of exposure (MOE). For non-threshold risks, the Agency assumes that any
amount of exposure will lead to some degree of risk. Thus, the Agency
estimates risk in terms of the probability of an occurrence of the
adverse effect expected in a lifetime. For more information on the
general principles EPA uses in risk characterization and a complete
description of the risk assessment process, see <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/assessing-human-health-risk-pesticides">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/assessing-human-health-risk-pesticides</a>.
A summary of the toxicological endpoints for metamitron used for
human risk assessment can be found on pages 24-25 in the ``Metamitron
Human Health Risk Assessment.''
C. Exposure Assessment
1. Dietary exposure from food and feed uses. In evaluating dietary
exposure to metamitron, EPA considered exposure under the petitioned-
for tolerances. EPA assessed dietary exposures from metamitron in food
as follows:
i. Acute and chronic exposure. Quantitative acute dietary exposure
and risk assessments are performed for a food-use pesticide, if a
toxicological study has indicated the possibility of an effect of
concern occurring as a result of a 1-day or single exposure. Such
effects were identified for metamitron. In estimating the acute and
chronic dietary exposure, EPA used food consumption information from
the United States Department of Agriculture (USDA) 2005-2010 National
Health and Nutrition Examination Survey, What We Eat in America
(NHANES/WWEIA). As to residue levels in food, EPA conducted unrefined
acute and chronic dietary exposure assessments for the proposed new
uses on apples and pears, based on combined level of quantification
(LOQ) field trial residues from parent compound metamitron and the
metabolite desamino-metamitron, default processing factors, and assumed
100 percent crop treated (PCT).
ii. Cancer. Based on the data summarized in Unit III.A., EPA has
concluded that metamitron does not pose a cancer risk to humans.
Therefore, a dietary exposure assessment for the purpose of assessing
cancer risk is unnecessary.
iii. Anticipated residue and percent crop treated (PCT)
information. EPA did not use anticipated residue and/or PCT information
in the dietary assessment for metamitron. Tolerance level residues and/
or 100% CT were assumed for all food commodities.
2. Dietary exposure from drinking water. The Agency used screening
level water exposure models in the dietary exposure analysis and risk
assessment for metamitron in drinking water. These simulation models
take into account data on the physical, chemical, and fate/transport
characteristics of metamitron. Further information regarding EPA
drinking water models used in pesticide exposure assessment can be
found at <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/models-pesticide-risk-assessment">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/models-pesticide-risk-assessment</a>.
Based on the Pesticide Water Calculator (PWC) model (ver. 2.001)
and new drinking water scenarios, the estimated drinking water
concentrations (EDWCs) of metamitron for acute exposures from
applications to apples and pears are estimated to be 17 parts per
billion (ppb) for surface water and 19 ppb for ground water, and for
chronic exposures for non-cancer assessments are estimated to be 5.3
ppb for surface water and 5.2 ppb for ground water. EPA used EDWCs for
sugar beet from a previously issued Section 18 Emergency Exemption to
represent protective high-end estimates for the proposed use on apples
and pears as well as sugar beet. The sugar beet surface water EDWCs of
91 ppb for acute and 61 ppb for chronic drinking water exposure were
directly incorporated into the assessments since surface water models
for sugar beet gave ~1.6 times higher water concentrations than those
from ground water models for sugar beet, and ~5 times higher water
concentrations than surface water and groundwater EDWCs from apples and
pears.
3. From non-dietary exposure. The term ``residential exposure'' is
used in this document to refer to non-occupational, non-dietary
exposure (e.g., for lawn and garden pest control, indoor pest control,
termiticides, and flea and tick control on pets). Metamitron is not
registered for any specific residential use patterns that would result
in residential exposure.
4. Cumulative effects from substances with a common mechanism of
toxicity. Section 408(b)(2)(D)(v) of FFDCA requires that, when
considering whether to establish, modify, or revoke a tolerance, the
Agency consider ``available information'' concerning the cumulative
effects of a particular pesticide's residues and ``other substances
that have a common mechanism of toxicity.''
EPA has not found metamitron to share a common mechanism of
toxicity with any other substances, and metamitron does not appear to
produce a toxic metabolite produced by other substances. For the
purposes of this tolerance action, therefore, EPA has assumed that
metamitron does not have a common mechanism of toxicity with other
substances. For information regarding EPA's efforts to determine which
chemicals have a common mechanism of toxicity and to evaluate the
cumulative effects of such chemicals, see EPA's website at <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/cumulative-assessment-risk-pesticides">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/cumulative-assessment-risk-pesticides</a>. As part of the ongoing process to review
registered pesticides, the Agency intends to apply this framework to
determine if the available toxicological data for metamitron suggests a
candidate common mechanism group (CMG) may be established with other
pesticides. If a CMG is established, a screening-level toxicology and
exposure analysis may be conducted to provide an initial screen for
multiple pesticide exposure.
D. Safety Factor for Infants and Children
1. In general. Section 408(b)(2)(C) of FFDCA provides that EPA
shall apply an additional tenfold (10X) margin of safety for infants
and children in the case of threshold effects to account for prenatal
and postnatal toxicity and the completeness of the database on toxicity
and exposure unless EPA determines based on reliable data that a
different margin of safety will be safe for infants and children. This
additional margin of safety is commonly referred to as the Food Quality
Protection Act (FQPA) Safety Factor (SF). In applying this provision,
EPA either retains the default value of 10X, or uses a different
additional safety factor when reliable data available to EPA support
the choice of a different factor.
2. Prenatal and postnatal sensitivity. There is no evidence of
increased susceptibility following in utero exposure to metamitron in
either the rat or rabbit developmental toxicity studies up to the
highest doses tested, and there is no evidence of increased
quantitative susceptibility following in utero and/or pre-/post-natal
exposure in the multi-generation reproduction studies in rats. All
offspring effects were observed at the same or higher dose level than
maternal toxicity. Evidence of qualitative sensitivity was demonstrated
in a multigeneration reproductive toxicity study, as decreased
offspring survival was observed in the absence of comparable parental
toxicity. However, the concern is low as the sensitivity was observed
at a higher dose level than the established LOAEL/NOAEL for the
parental generation, a clear NOAEL/LOAEL has been established for the
offspring generation, and all selected
[[Page 11673]]
endpoints are protective of the qualitative sensitivity.
3. Conclusion. EPA has determined that reliable data show the
safety of infants and children would be adequately protected if the
FQPA SF were reduced to 1X. That decision is based on the following
findings:
i. The toxicity database for metamitron is complete and adequate to
characterize potential pre- and postnatal toxicity to infants and
children.
ii. Neurotoxicity (clinical signs and functional observational
battery (FOB) findings) was observed following an acute exposure
(single dose) in both mice and rats. In a metabolism study, reduced
mobility and piloerection were observed after a single oral dose, but
the effects resolved within 24 hours post-dosage. No additional
potentially neurotoxic effects were observed across the metamitron
database, including the rat subchronic neurotoxicity study (SCN), at
the doses tested. The concern for neurotoxicity is low, as all selected
PODs are protective of the adverse effects identified in the non-
guideline studies and the metabolism study.
iii. There is no evidence that metamitron results in increased
quantitative susceptibility in rats or rabbits in the prenatal
developmental studies. Evidence of qualitative sensitivity was
demonstrated in a multigeneration reproductive toxicity study, as
decreased offspring survival was observed in the absence of comparable
parental toxicity. However, the concern is low as the sensitivity was
observed at a higher dose level than the established LOAEL/NOAEL for
the parental generation, a clear NOAEL/LOAEL has been established for
the offspring generation, and all selected endpoints are protective of
the qualitative sensitivity.
iv. There are no residual uncertainties identified in the exposure
databases. The dietary food exposure assessments were performed based
on 100 PCT, field trial level residues, and upper-bound estimates of
potential exposure through drinking water. EPA made conservative
(protective) assumptions in the ground and surface water modeling used
to assess exposure to metamitron in drinking water. These assessments
will not underestimate the exposure and risks posed by metamitron.
E. Aggregate Risks and Determination of Safety
EPA determines whether acute and chronic dietary pesticide
exposures are safe by comparing aggregate exposure estimates to the
acute PAD (aPAD) and chronic PAD (cPAD). For linear cancer risks, EPA
calculates the lifetime probability of acquiring cancer given the
estimated aggregate exposure. Short-, intermediate-, and chronic-term
risks are evaluated by comparing the estimated aggregate food, water,
and residential exposure to the appropriate PODs to ensure that an
adequate MOE exists.
1. Acute risk. Using the exposure assumptions discussed in this
unit for acute exposure, the acute dietary exposure from food and water
to metamitron will occupy 5.6% of the aPAD for all infants (<1 year
old), the population group receiving the greatest exposure.
2. Chronic risk. Using the exposure assumptions described in this
unit for chronic exposure, EPA has concluded that chronic exposure to
metamitron from food and water will utilize 5.3% of the cPAD for all
infants (<1 year old), the population group receiving the greatest
exposure. There are no residential uses for metamitron.
3. Short-term and intermediate-term risk. Short-term aggregate
exposure takes into account short-term residential exposure plus
chronic exposure to food and water (considered to be a background
exposure level). Intermediate-term aggregate exposure takes into
account intermediate-term residential exposure plus chronic exposure to
food and water (considered to be a background exposure level). Since
there are no proposed residential uses for metamitron that would result
in short- or intermediate-term residential exposures, and chronic
dietary exposure has already been assessed under the appropriately
protective cPAD (which is at least as protective as the POD used to
assess short- and intermediate-term risk), no further assessment of
short- or intermediate-term risk is necessary, and EPA relies on the
chronic dietary risk assessment for evaluating short- and intermediate-
term risk for metamitron.
4. Aggregate cancer risk for U.S. population. Based on the lack of
evidence of carcinogenicity in two adequate rodent carcinogenicity
studies and the low concern for mutagenic potential, metamitron is not
expected to pose a cancer risk to humans; therefore, a separate cancer
assessment was not conducted.
5. Determination of safety. Based on these risk assessments, EPA
concludes that there is a reasonable certainty that no harm will result
to the general population, or to infants and children from aggregate
exposure to metamitron residues.
IV. Other Considerations
A. Analytical Enforcement Methodology
Adequate enforcement methodology (high-performance liquid
chromatography with tandem mass spectrometry detection (LC/MS/MS)
(Method SGS-17-01-03)) is available to enforce the tolerance
expression. The method may be requested from: Chief, Analytical
Chemistry Branch, Environmental Science Center, 701 Mapes Rd., Ft.
Meade, MD 20755-5350; telephone number: (410) 305-2905; email address:
<a href="/cdn-cgi/l/email-protection#493b2c3a202d3c2c242c3d21262d3a092c3928672e263f"><span class="__cf_email__" data-cfemail="6f1d0a1c060b1a0a020a1b07000b1c2f0a1f0e41080019">[email protected]</span></a>.
B. International Residue Limits
In making its tolerance decisions, EPA seeks to harmonize U.S.
tolerances with international standards whenever possible, consistent
with U.S. food safety standards and agricultural practices. EPA
considers the international maximum residue limits (MRLs) established
by the Codex Alimentarius Commission (Codex), as required by FFDCA
section 408(b)(4). The Codex Alimentarius is a joint United Nations
Food and Agriculture Organization/World Health Organization food
standards program, and it is recognized as an international food safety
standards-setting organization in trade agreements to which the United
States is a party. EPA may establish a tolerance that is different from
a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain
the reasons for departing from the Codex level.
The Codex has not established a MRL for metamitron.
V. Conclusion
Therefore, tolerances are established for residues of metamitron,
including its metabolites and degradates, in or on apple and pear at
0.01 ppm.
VI. Statutory and Executive Order Reviews
This action establishes tolerances under FFDCA section 408(d) in
response to a petition submitted to the Agency. The Office of
Management and Budget (OMB) has exempted these types of actions from
review under Executive Order 12866, entitled ``Regulatory Planning and
Review'' (58 FR 51735, October 4, 1993). Because this action has been
exempted from review under Executive Order 12866, this action is not
subject to Executive Order 13211, entitled ``Actions Concerning
Regulations That Significantly Affect Energy Supply, Distribution, or
Use'' (66 FR 28355, May 22, 2001) or Executive Order 13045, entitled
``Protection of
[[Page 11674]]
Children from Environmental Health Risks and Safety Risks'' (62 FR
19885, April 23, 1997). This action does not contain any information
collections subject to OMB approval under the Paperwork Reduction Act
(PRA) (44 U.S.C. 3501 et seq.).
Since tolerances and exemptions that are established on the basis
of a petition under FFDCA section 408(d), such as the tolerance in this
final rule, do not require the issuance of a proposed rule, the
requirements of the Regulatory Flexibility Act (RFA) (5 U.S.C. 601 et
seq.), do not apply.
This action directly regulates growers, food processors, food
handlers, and food retailers, not States or tribes, nor does this
action alter the relationships or distribution of power and
responsibilities established by Congress in the preemption provisions
of FFDCA section 408(n)(4). As such, the Agency has determined that
this action will not have a substantial direct effect on States or
Tribal governments, on the relationship between the national government
and the States or Tribal governments, or on the distribution of power
and responsibilities among the various levels of government or between
the Federal Government and Indian tribes. Thus, the Agency has
determined that Executive Order 13132, entitled ``Federalism'' (64 FR
43255, August 10, 1999) and Executive Order 13175, entitled
``Consultation and Coordination with Indian Tribal Governments'' (65 FR
67249, November 9, 2000) do not apply to this action. In addition, this
action does not impose any enforceable duty or contain any unfunded
mandate as described under Title II of the Unfunded Mandates Reform Act
(UMRA) (2 U.S.C. 1501 et seq.).
This action does not involve any technical standards that would
require Agency consideration of voluntary consensus standards pursuant
to section 12(d) of the National Technology Transfer and Advancement
Act (NTTAA) (15 U.S.C. 272 note).
VII. Congressional Review Act (CRA)
This action is subject to the CRA (5 U.S.C. 801 et seq.), and EPA
will submit a rule report to each House of the Congress and to the
Comptroller General of the United States. This action is not a ``major
rule'' as defined by 5 U.S.C. 804(2).
List of Subjects in 40 CFR Part 180
Environmental protection, Administrative practice and procedure,
Agricultural commodities, Pesticides and pests, Reporting and
recordkeeping requirements.
Dated: March 3, 2025.
Edward Messina,
Director, Office of Pesticide Programs.
Therefore, for the reasons stated in the preamble, EPA is amending
40 CFR chapter I as follows:
PART 180--TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES
IN FOOD
0
1. The authority citation for part 180 continues to read as follows:
Authority: 21 U.S.C. 321(q), 346a and 371.
0
2. In Sec. 180.726, add paragraph (a) to read as follows:
Sec. 180.726 Metamitron; tolerances for residues.
(a) General. Tolerances are established for residues of the
herbicide metamitron, including its metabolites and degradates, in or
on the commodities in table 1 to this paragraph (a). Compliance with
the tolerance levels specified in table 1 to this paragraph (a) is to
be determined by measuring residues of metamitron (4-amino-3-methyl-6-
phenyl-1,2,4-triazin-5(4H)-one) in or on the following commodities:
Table 1 to Paragraph (a)
------------------------------------------------------------------------
Parts per
Commodity million
------------------------------------------------------------------------
Apple....................................................... 0.01
Pear........................................................ 0.01
------------------------------------------------------------------------
* * * * *
[FR Doc. 2025-03872 Filed 3-10-25; 8:45 am]
BILLING CODE 6560-50-P
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