Notice2024-24514

NIST Consortium for Advancement of Genome Editing

Primary source

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Published
October 23, 2024

Issuing agencies

Commerce DepartmentNational Institute of Standards and Technology

Abstract

The National Institute of Standards and Technology (NIST) extends the duration of the NIST Consortium for Advancement of Genome Editing (Genome Editing Consortium or Consortium). The Consortium duration was previously through December 1, 2025. NIST is taking this action to provide additional time for interested parties to join the Consortium to further pursue the implementation and achievement of outcomes of the current Consortium activities, as well as to address additional standards needs as defined by the Consortium in qualification of off-target assays and quality of genome editing components. Beginning January 1, 2026 participation fees will increase to $25,000 annually or in-kind contributions of equivalent value. Participants will be required to sign a Cooperative Research and Development Agreement (CRADA).

Full Text

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<title>Federal Register, Volume 89 Issue 205 (Wednesday, October 23, 2024)</title>
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[Federal Register Volume 89, Number 205 (Wednesday, October 23, 2024)]
[Notices]
[Page 84534]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2024-24514]



[[Page 84534]]

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DEPARTMENT OF COMMERCE

National Institute of Standards and Technology


NIST Consortium for Advancement of Genome Editing

AGENCY: National Institute of Standards and Technology, Department of 
Commerce.

ACTION: Notice of Research Consortium; Extension of Research 
Consortium.

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SUMMARY: The National Institute of Standards and Technology (NIST) 
extends the duration of the NIST Consortium for Advancement of Genome 
Editing (Genome Editing Consortium or Consortium). The Consortium 
duration was previously through December 1, 2025. NIST is taking this 
action to provide additional time for interested parties to join the 
Consortium to further pursue the implementation and achievement of 
outcomes of the current Consortium activities, as well as to address 
additional standards needs as defined by the Consortium in 
qualification of off-target assays and quality of genome editing 
components. Beginning January 1, 2026 participation fees will increase 
to $25,000 annually or in-kind contributions of equivalent value. 
Participants will be required to sign a Cooperative Research and 
Development Agreement (CRADA).

DATES: The Consortium's activities will continue as needed to complete 
the updated research plan. NIST will accept letters of interest to 
participate in this Consortium on an ongoing basis. Acceptance of 
participants into the Consortium will depend on the availability of 
resources.

ADDRESSES: Information in response to this notice, including completed 
letters of interest or requests for additional information about the 
Consortium, can be directed via mail to the Consortium Manager, Dr. 
Samantha Maragh, Biosystems and Biomaterials Division of NIST's 
Material Measurement Laboratory, 100 Bureau Drive, Mail Stop 8312, 
Gaithersburg, Maryland 20899 or via electronic mail to 
<a href="/cdn-cgi/l/email-protection#0271636f636c766a63426c6b71762c656d74"><span class="__cf_email__" data-cfemail="74071519151a001c15341a1d07005a131b02">[email&#160;protected]</span></a>, or by telephone at (301) 975-4947.

SUPPLEMENTARY INFORMATION: On January 11, 2018, NIST published a notice 
in the Federal Register (83 FR 1335), establishing the Consortium, and 
on February 2, 2021, NIST published a notice in the Federal Register 
(86 FR 7859) extending the duration of the Consortium until December 1, 
2025. To provide additional time for interested parties to join the 
Consortium to further pursue the implementation and achievement of the 
Consortium objectives, NIST extends the term to continue as needed to 
complete the updated research plan and will accept letters of interest 
on an ongoing basis. Previously submitted letters of interest do not 
need to be resubmitted.
    The Consortium's current activities (as described in the original 
notice, 83 FR 1335) will continue, and the Consortium research plan is 
amended to include the following new activities:
    Qualification of Off-Target Assays: Identify sources of variability 
and develop consensus approaches to qualifying off-target assays 
(including potential interlaboratory studies or control materials).
    Quality of Genome Editing Components: Identify concepts/
information, approaches/assays, and potential controls for assessing 
quality of genome editing components.

Alicia Chambers,
NIST Executive Secretariat.
[FR Doc. 2024-24514 Filed 10-22-24; 8:45 am]
BILLING CODE 3510-13-P


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Indexed from Federal Register on October 23, 2024.

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