Notice2024-00758
Interagency Coordinating Committee on the Validation of Alternative Methods Communities of Practice Webinar on Implementing Computational Approaches for Regulatory Safety Assessments; Notice of Public Webinar; Registration Information
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Published
January 17, 2024
Issuing agencies
Health and Human Services DepartmentNational Institutes of Health
Abstract
The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) announces the public webinar "Implementing Computational Approaches for Regulatory Safety Assessments." The webinar is organized on behalf of ICCVAM by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM). Interested persons may participate via the web meeting platform. Time will be allotted for questions from the audience. Information about the webinar and registration are available at https://ntp.niehs.nih.gov/go/commprac- 2024.
Full Text
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<title>Federal Register, Volume 89 Issue 11 (Wednesday, January 17, 2024)</title>
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[Federal Register Volume 89, Number 11 (Wednesday, January 17, 2024)]
[Notices]
[Pages 2963-2964]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2024-00758]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
Interagency Coordinating Committee on the Validation of
Alternative Methods Communities of Practice Webinar on Implementing
Computational Approaches for Regulatory Safety Assessments; Notice of
Public Webinar; Registration Information
AGENCY: National Institutes of Health, HHS.
ACTION: Notice.
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SUMMARY: The Interagency Coordinating Committee on the Validation of
Alternative Methods (ICCVAM) announces the public webinar
``Implementing Computational Approaches for Regulatory Safety
Assessments.'' The webinar is organized on behalf of ICCVAM by the
National Toxicology Program Interagency Center for the Evaluation of
Alternative Toxicological Methods (NICEATM). Interested persons may
participate via the web meeting platform. Time will be allotted for
questions from the audience. Information about the webinar and
registration are available at <a href="https://ntp.niehs.nih.gov/go/commprac-2024">https://ntp.niehs.nih.gov/go/commprac-2024</a>.
DATES:
Webinar: January 29, 2024, 10 a.m. to approximately 12 noon EST.
Registration for Webinar: January 10, 2024, until 12:00 noon EST
January 29, 2024. Registration to view the webinar is required.
ADDRESSES: Webinar web page: <a href="https://ntp.niehs.nih.gov/go/commprac-2024">https://ntp.niehs.nih.gov/go/commprac-2024</a>.
FOR FURTHER INFORMATION CONTACT: Dr. Helena Hogberg, Staff Scientist,
NICEATM, email: <a href="/cdn-cgi/l/email-protection#29414c454c47480741464e4b4c5b4e044d5c5b4d464a4269474041074e465f"><span class="__cf_email__" data-cfemail="6008050c050e014e080f07020512074d041512040f030b200e09084e070f16">[email protected]</span></a>, telephone: (984) 287-
3150.
SUPPLEMENTARY INFORMATION:
Background: ICCVAM promotes the development and validation of
toxicity testing methods that protect human health and the environment
while replacing, reducing, or refining animal use. ICCVAM also provides
guidance to test method developers and facilitates collaborations that
promote the development of new test methods. To address these goals,
ICCVAM will hold a Communities of Practice webinar on ``Implementing
Computational Approaches for Regulatory Safety Assessments.''
Computational toxicology methods can be useful for generating
bioactivity predictions for chemicals for which limited toxicity data
are available. They can also help users understand and interpret large,
diverse bioactivity data sets, or predict how a chemical might behave
in the body. However, users with limited experience with such methods
may find it difficult to use them or interpret their outputs, or even
understand how the methods could be applied in a specific context.
This webinar will discuss how to establish confidence in
computational approaches for regulatory applications. Ongoing
activities and key insights will be described in three presentations by
speakers from the U.S. government and the private sector focusing on
applications of tools such as structure-based models to predict
chemical bioactivity and pharmacokinetic models to support
understanding of chemical metabolism and disposition. The preliminary
agenda and additional information about presentations will be posted at
<a href="https://ntp.niehs.nih.gov/go/commprac-2024">https://ntp.niehs.nih.gov/go/commprac-2024</a> as they become available.
Webinar and Registration: This webinar is open to the public with
time scheduled for questions by participants following each
presentation. Registration for the webinar is required. Registration
will open on or before January 10, 2024, and remain open through 12
noon EST on January 29, 2024. Registration is available at <a href="https://ntp.niehs.nih.gov/go/commprac-2024">https://ntp.niehs.nih.gov/go/commprac-2024</a>. Interested individuals are
encouraged to visit this web page to stay abreast of the most current
webinar information. Registrants will receive instructions on how to
access and participate in the webinar in the email confirming their
registration. TTY users should contact the Federal TTY Relay Service at
800-877-8339. Requests should be made at least five business days in
advance of the event.
Background Information on ICCVAM and NICEATM: ICCVAM is an
interagency committee composed of representatives from 17 Federal
regulatory and research agencies that require, use, generate, or
disseminate toxicological and safety testing information. ICCVAM
conducts technical evaluations of new, revised, and alternative safety
testing methods and integrated testing strategies with regulatory
applicability. ICCVAM also promotes the scientific validation and
regulatory acceptance of testing methods that more accurately assess
the safety and hazards of chemicals and products and replace, reduce,
or refine animal use.
The ICCVAM Authorization Act of 2000 (42 U.S.C. 285l-3) establishes
ICCVAM as a permanent interagency committee of the National Institute
of Environmental Health Sciences and provides the authority for ICCVAM
involvement in activities relevant to the development of alternative
test methods. Additional information about ICCVAM can be found at
<a href="https://ntp.niehs.nih.gov/go/iccvam">https://ntp.niehs.nih.gov/go/iccvam</a>.
NICEATM administers ICCVAM, provides support for ICCVAM-related
activities, and conducts and publishes analyses and evaluations of data
from new, revised, and alternative testing approaches. NICEATM and
ICCVAM work collaboratively to evaluate new and improved testing
approaches applicable to the needs of U.S. Federal agencies. NICEATM
and ICCVAM welcome the public nomination of new,
[[Page 2964]]
revised, and alternative test methods and strategies for validation
studies and technical evaluations. Additional information about NICEATM
can be found at <a href="https://ntp.niehs.nih.gov/go/niceatm">https://ntp.niehs.nih.gov/go/niceatm</a>.
Dated: January 10, 2024.
Richard P. Woychik,
Director, National Institute of Environmental Health Sciences and
National Toxicology Program, National Institutes of Health.
[FR Doc. 2024-00758 Filed 1-16-24; 8:45 am]
BILLING CODE 4140-01-P
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