Notice2023-24746
Availability of the Protocol for the Nitrate and Nitrite IRIS Assessment (Oral)
Primary source
Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.
Published
November 9, 2023
Issuing agencies
Environmental Protection Agency
Abstract
The Environmental Protection Agency (EPA) is announcing a 30- day public comment period associated with release of the document Protocol for the Nitrate and Nitrite IRIS Assessment (Oral). This document communicates the rationale for conducting the human health assessment of Nitrate and Nitrite, describes screening criteria to identify relevant literature, outlines the approach for evaluating study quality, and describes the methods for dose-response analysis.
Full Text
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<title>Federal Register, Volume 88 Issue 216 (Thursday, November 9, 2023)</title>
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[Federal Register Volume 88, Number 216 (Thursday, November 9, 2023)]
[Notices]
[Page 77310]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2023-24746]
[[Page 77310]]
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ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-ORD-2017-0496; FRL-11545-01-ORD]
Availability of the Protocol for the Nitrate and Nitrite IRIS
Assessment (Oral)
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of public comment period.
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SUMMARY: The Environmental Protection Agency (EPA) is announcing a 30-
day public comment period associated with release of the document
Protocol for the Nitrate and Nitrite IRIS Assessment (Oral). This
document communicates the rationale for conducting the human health
assessment of Nitrate and Nitrite, describes screening criteria to
identify relevant literature, outlines the approach for evaluating
study quality, and describes the methods for dose-response analysis.
DATES: The 30-day public comment period begins November 9, 2023 and
ends December 11, 2023. Comments must be received on or before December
11, 2023.
ADDRESSES: The Protocol for the Nitrate and Nitrite IRIS Assessment
(Oral) will be available via the internet on the IRIS website at
<a href="https://www.epa.gov/iris">https://www.epa.gov/iris</a> and in the public docket at <a href="http://www.regulations.gov">http://www.regulations.gov</a>, Docket ID: EPA-HQ-ORD-2017-0496.
FOR FURTHER INFORMATION CONTACT: For information on the docket, contact
the ORD Docket at the EPA Headquarters Docket Center; email:
<a href="/cdn-cgi/l/email-protection#cd89a2aea6a8b992829f898da8bdace3aaa2bb"><span class="__cf_email__" data-cfemail="2b6f4448404e5f7464796f6b4e5b4a054c445d">[email protected]</span></a>.
For technical information on the protocol, contact Mr. Dahnish
Shams, Center for Public Health & Environmental Assessment; email:
<a href="/cdn-cgi/l/email-protection#5a29323b3729743e3b32343329321a3f2a3b743d352c"><span class="__cf_email__" data-cfemail="4a39222b2739642e2b22242339220a2f3a2b642d253c">[email protected]</span></a>.
SUPPLEMENTARY INFORMATION:
I. Background Information on the IRIS Program and Systematic Review
Protocols
EPA's IRIS Program is a human health assessment program that
evaluates quantitative and qualitative information on effects that may
result from exposure to chemicals found in the environment. Through the
IRIS Program, EPA provides high quality science-based human health
assessments to support the Agency's regulatory activities and decisions
to protect public health.
As part of developing a draft IRIS assessment, EPA presents a
methods document, referred to as the protocol, for conducting a
chemical-specific systematic review of the available scientific
literature. EPA is seeking public comment on components of the protocol
including the described strategies for literature searches, criteria
for study inclusion or exclusion, considerations for evaluating study
methods, information management for extracting data, approaches for
synthesis within and across lines of evidence, and methods for
derivation of toxicity values. The protocol serves to inform the
subsequent development of the draft assessment and is made available to
the public. EPA may update the protocol based on the evaluation of the
literature, and any updates will be posted to the docket and on the
IRIS website.
II. How to Submit Technical Comments to the Docket at <a href="https://www.regulations.gov">https://www.regulations.gov</a>
Submit your comments, identified by Docket ID No. EPA-HQ-ORD-2017-
0496 for Nitrate/Nitrite, by one of the following methods:
<bullet> <a href="http://www.regulations.gov">www.regulations.gov</a>: Follow the on-line instructions for
submitting comments.
<bullet> Email: <a href="/cdn-cgi/l/email-protection#03476c606866775c4c5147436673622d646c75"><span class="__cf_email__" data-cfemail="bbffd4d8d0decfe4f4e9fffbdecbda95dcd4cd">[email protected]</span></a>.
<bullet> Fax: 202-566-9744.
<bullet> Mail: U.S. Environmental Protection Agency, EPA Docket
Center (ORD Docket), Mail Code: 28221T, 1200 Pennsylvania Avenue NW,
Washington, DC 20460. The phone number is 202-566-1752.
For information on visiting the EPA Docket Center Public Reading
Room, visit <a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>. The telephone number for the
Public Reading Room is 202-566-1744. The public can submit comments via
<a href="http://www.regulations.gov">www.regulations.gov</a> or email.
Instructions: Direct your comments to docket number EPA-HQ-ORD-
2017-0496 for nitrate/nitrite. Please ensure that your comments are
submitted within the specified comment period. Comments received after
the closing date will be marked ``late,'' and may only be considered if
time permits. It is EPA's policy to include all comments it receives in
the public docket without change and to make the comments available
online at <a href="https://www.regulations.gov">https://www.regulations.gov</a>, including any personal
information provided, unless a comment includes information claimed to
be Confidential Business Information (CBI) or other information for
which disclosure is restricted by statute. Do not submit information
through <a href="https://www.regulations.gov">https://www.regulations.gov</a> or email that you consider to be
CBI or otherwise protected. The <a href="https://www.regulations.gov">https://www.regulations.gov</a> website is
an ``anonymous access'' system, which means EPA will not know your
identity or contact information unless you provide it in the body of
your comment. If you send an email comment directly to EPA without
going through <a href="https://www.regulations.gov">https://www.regulations.gov</a>, your email address will be
automatically captured and included as part of the comment that is
placed in the public docket and made available on the internet. If you
submit an electronic comment, EPA recommends that you include your name
and other contact information in the body of your comment and with any
disk or CD-ROM you submit. If EPA cannot read your comment due to
technical difficulties and cannot contact you for clarification, EPA
may not be able to consider your comment. Electronic files should avoid
the use of special characters, any form of encryption, and be free of
any defects or viruses. For additional information about EPA's public
docket, visit the EPA Docket Center homepage at <a href="https://www.epa.gov/dockets">https://www.epa.gov/dockets</a>.
Docket: Documents in the docket are listed in the <a href="https://www.regulations.gov">https://www.regulations.gov</a> index. Although listed in the index, some
information is not publicly available, e.g., CBI or other information
whose disclosure is restricted by statute. Certain other materials,
such as copyrighted material, are publicly available only in hard copy.
Publicly available docket materials are available either electronically
in <a href="https://www.regulations.gov">https://www.regulations.gov</a> or as a hard copy at the ORD Docket in
the EPA Headquarters Docket Center.
Wayne Cascio,
Director, Center for Public Health & Environmental Assessment.
[FR Doc. 2023-24746 Filed 11-8-23; 8:45 am]
BILLING CODE 6560-50-P
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