Notice2023-03194
Request for Public Nominations of Experts To Serve on a Review Panel
Primary source
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Published
February 15, 2023
Issuing agencies
Environmental Protection Agency
Abstract
The U.S. Environmental Protection Agency (EPA) is seeking nominations for technical experts to serve as Special Government Employees (SGEs) on a review panel under the authority of the Board of Scientific Counselors (BOSC), a federal advisory committee to the Office of Research and Development (ORD). Selected experts will review ORD's draft documents detailing scientific studies supporting the development of transcriptomic-based toxicity values and their implementation as a new EPA Transcriptomic Assessment Product (ETAP). The ETAP is a proposed ORD assessment product that utilizes a standardized short-term in vivo study design and data analysis procedures to develop transcriptomic-based toxicity values for data poor chemicals. The review will take place between April and July 2023. Submission of nominations should be made via the BOSC website at: https://www.epa.gov/bosc.
Full Text
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<title>Federal Register, Volume 88 Issue 31 (Wednesday, February 15, 2023)</title>
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[Federal Register Volume 88, Number 31 (Wednesday, February 15, 2023)]
[Notices]
[Pages 9880-9881]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2023-03194]
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ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-ORD-2015-0765; FRL-10670-01-ORD]
Request for Public Nominations of Experts To Serve on a Review
Panel
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice.
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SUMMARY: The U.S. Environmental Protection Agency (EPA) is seeking
nominations for technical experts to serve as Special Government
Employees (SGEs) on a review panel under the authority of the Board of
Scientific Counselors (BOSC), a federal advisory committee to the
Office of Research and Development (ORD). Selected experts will review
ORD's draft documents detailing scientific studies supporting the
development of transcriptomic-based toxicity values and their
implementation as a new EPA Transcriptomic Assessment Product (ETAP).
The ETAP is a proposed ORD assessment product that utilizes a
standardized short-term in vivo study design and data analysis
procedures to develop transcriptomic-based toxicity values for data
poor chemicals. The review will take place between April and July 2023.
Submission of nominations should be made via the BOSC website at:
<a href="https://www.epa.gov/bosc">https://www.epa.gov/bosc</a>.
DATES: Nominations should be submitted by March 3, 2023, per
instructions below.
FOR FURTHER INFORMATION CONTACT: Any member of the public needing
additional information regarding this Notice and Request for
Nominations may contact Mr. Tom Tracy, Office of Science Policy, Office
of Research and Development, Mail Code B343-01, 109 T.W. Alexander
Drive, Research
[[Page 9881]]
Triangle Park, NC 27711; via phone/voice mail at: (919) 541-4334; or
via email at: <a href="/cdn-cgi/l/email-protection#e5919784869ccb918a88a5809584cb828a93"><span class="__cf_email__" data-cfemail="54202635372d7a203b39143124357a333b22">[email protected]</span></a>. General information concerning the
BOSC can be found at the following website: <a href="https://www.epa.gov/bosc">https://www.epa.gov/bosc</a>.
SUPPLEMENTARY INFORMATION:
Background
The BOSC is a chartered Federal Advisory Committee established by
the EPA to provide independent scientific and technical peer review,
advice, consultation, and recommendations about ORD. As a Federal
Advisory Committee, the BOSC conducts business in accordance with the
Federal Advisory Committee Act (FACA) (5 U.S.C. App. 2) and related
regulations.
The BOSC is comprised of an Executive Committee and two supporting
subcommittee(s): Social and Community Science, and Climate Change.
Please visit <a href="https://www.epa.gov/aboutepa/about-office-research-and-development-ord">https://www.epa.gov/aboutepa/about-office-research-and-development-ord</a> to learn more about ORD's research programs.
Members of the BOSC constitute a distinguished body of non-EPA
scientists, engineers, and economists who are experts in their
respective fields. The chartered BOSC provides scientific advice to the
EPA Administrator on a variety of EPA science and research topics. All
the work of BOSC standing committees and ad-hoc panels is conducted
under the auspices of the chartered BOSC. The chartered BOSC members
review all BOSC standing committee and ad-hoc panel draft reports and
determine whether each meets the BOSC's criteria and high-quality
standards required to deliver them to the EPA Administrator.
The BOSC will evaluate the Office of Research and Development
(ORD)'s draft scientific studies supporting the development of
transcriptomic-based toxicity values and their use as a new EPA
Transcriptomic Assessment Product (ETAP). Draft documents will be
provided in the BOSC docket prior to the meeting for an in-depth
evaluation of:
<bullet> Literature review and scientific studies supporting the
development of transcriptomic points-of-departure from short-term in
vivo studies;
<bullet> Derivation of transcriptomic toxicity values for chronic
toxicity; and
<bullet> Incorporation of transcriptomic toxicity values into a new
standardized assessment product that is intended for data poor
chemicals.
<bullet> Example application of the ETAP to a data poor per- and
polyfluoroalkyl substance (PFAS).
The review of the draft documents detailing underlying scientific
studies and implementation of ETAP by the BOSC is being performed in
close coordination with a separate BOSC review of a value-of-
information (VOI) analysis comparing the ETAP with traditional human
health assessment practices. The VOI analysis is intended to evaluate
the public health and economic trade-offs associated with the
timeliness, uncertainty, and costs of the different toxicity evaluation
and assessment approaches.
Expertise Sought
The EPA invites nominations of individuals to serve as SGEs with
expertise or extensive experience in the following scientific
disciplines and topic areas as they relate to human health and the
environment:
<bullet> Human health chemical risk assessment
<bullet> Toxicology
<bullet> Biostatistics
<bullet> Transcriptomics, including dose response modeling of
transcriptomic data
<bullet> Systematic evidence mapping
Selection Criteria
Nominations will be evaluated on the basis of several criteria
including: (a) demonstrated scientific and/or technical credentials and
disciplinary expertise, knowledge, and experience in relevant fields;
(b) availability to serve and willingness to commit time to the
committee (approximately one to three meetings both by teleconferences
and possibly face-to-face meetings); (c) absence of financial conflicts
of interest; (d) absence of an appearance of a lack of impartiality;
(e) demonstrated ability to work constructively and effectively on
committees; and (f) background and experiences that would contribute to
the diversity of viewpoints on the Executive Committee or Subcommittee,
e.g., workforce sector, geographical location, social, cultural, and
educational backgrounds, and professional affiliations.
Process and Deadline for Submitting Nominations
Any interested person or organization may nominate qualified
persons to be considered for appointment to the advisory committee.
Nominations should be submitted via the BOSC website at: <a href="https://www.epa.gov/bosc">https://www.epa.gov/bosc</a>. Nominations should be submitted no later than March
3, 2023. To receive full consideration, nominations should include all
the information requested. EPA's nomination form requests: contact
information about the person making the nomination; contact information
about the nominee; the disciplinary and specific areas of expertise of
the nominee; the nominee's curriculum vita and/or resume; and
additional information that would be useful for considering the
nomination such as background and qualifications (e.g., current
position, educational background, expertise, research areas),
experience relevant to one or more of ORD's research programs, service
on other advisory committees and professional societies, and
availability to participate as an SGE. Persons having questions about
the nomination procedures, or who are unable to submit nominations
through the BOSC website, should contact Mr. Tom Tracy, as indicated
above under FOR FURTHER INFORMATION CONTACT section of this notice.
Mary Ross,
Director, Office of Science Advisor, Policy and Engagement.
[FR Doc. 2023-03194 Filed 2-14-23; 8:45 am]
BILLING CODE 6560-50-P
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