Notice2023-00147
Interagency Coordinating Committee on the Validation of Alternative Methods Communities of Practice Webinar on Emerging Approaches for Anchoring Biological Relevance of New Approach Methodologies; Notice of Public Webinar; Registration Information
Primary source
Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.
Published
January 9, 2023
Issuing agencies
Health and Human Services DepartmentNational Institutes of Health
Abstract
The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) announces a public webinar "Emerging Approaches for Anchoring Biological Relevance of New Approach Methodologies." The webinar is organized on behalf of ICCVAM by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM). Interested persons may participate via the web meeting platform. Time will be allotted for questions from the audience. Information about the webinar and registration are available at https://ntp.niehs.nih.gov/go/commprac- 2023.
Full Text
<html>
<head>
<title>Federal Register, Volume 88 Issue 5 (Monday, January 9, 2023)</title>
</head>
<body><pre>
[Federal Register Volume 88, Number 5 (Monday, January 9, 2023)]
[Notices]
[Pages 1240-1241]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2023-00147]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
Interagency Coordinating Committee on the Validation of
Alternative Methods Communities of Practice Webinar on Emerging
Approaches for Anchoring Biological Relevance of New Approach
Methodologies; Notice of Public Webinar; Registration Information
AGENCY: National Institutes of Health, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The Interagency Coordinating Committee on the Validation of
Alternative Methods (ICCVAM) announces a public webinar ``Emerging
Approaches for Anchoring Biological Relevance of New Approach
Methodologies.'' The webinar is organized on behalf of ICCVAM by the
National Toxicology Program Interagency Center for the Evaluation of
Alternative Toxicological Methods (NICEATM). Interested persons may
participate via the web meeting platform. Time will be allotted for
questions from the audience. Information about the webinar and
registration are available at <a href="https://ntp.niehs.nih.gov/go/commprac-2023">https://ntp.niehs.nih.gov/go/commprac-2023</a>.
DATES:
Webinar: January 30, 2023, 10:00 a.m. to approximately 12:00 noon
EST.
Registration for Webinar: January 10, 2023, until 12:00 noon EST
January 30, 2023. Registration to view the webinar is required.
ADDRESSES: Webinar web page: <a href="https://ntp.niehs.nih.gov/go/commprac-2023">https://ntp.niehs.nih.gov/go/commprac-2023</a>.
FOR FURTHER INFORMATION CONTACT: Dr. Nicole Kleinstreuer, Director,
NICEATM, email: <a href="/cdn-cgi/l/email-protection#d8b6b1bbb7b4bdf6b3b4bdb1b6abacaabdadbdaa98b6b1b0f6bfb7ae"><span class="__cf_email__" data-cfemail="335d5a505c5f561d585f565a5d40474156465641735d5a5b1d545c45">[email protected]</span></a>, telephone: (984) 287-3150.
SUPPLEMENTARY INFORMATION:
Background: ICCVAM promotes the development and validation of
toxicity testing methods that protect human health and the environment
while replacing, reducing, or refining animal use. ICCVAM also provides
guidance to test method developers and facilitates collaborations that
promote the development of new test methods. To address these goals,
ICCVAM will hold a Communities of Practice webinar on ``Emerging
Approaches for Anchoring Biological Relevance of New Approach
Methodologies.''
``New approach methodologies'' (NAMs) refers to approaches that can
be used alone or in combination to provide information on chemical
hazard and risk assessment without traditional animal tests.
Traditional approaches to evaluating NAMs consider how well the results
of chemical tests using NAMs correspond with the results of animal
tests of the same chemicals. However, the usefulness of this approach
is limited, especially when the animal results are variable, or the
animal model does not adequately represent the species or effect of
regulatory interest.
This webinar will discuss approaches to build confidence in NAMs
that are based on evaluating the biological relevance of the NAM to the
species of regulatory interest. Ongoing activities and key insights
will be described in three presentations by speakers from the academic
and private sector focusing on applications of small model organisms,
organs-on-chips, and models of absorption, distribution, metabolism,
and excretion. The preliminary agenda and additional information about
presentations will be posted at <a href="https://ntp.niehs.nih.gov/go/commprac-2023">https://ntp.niehs.nih.gov/go/commprac-2023</a> as available.
Webinar and Registration: This webinar is open to the public with
time scheduled for questions by participants following each
presentation. Registration for the webinar is required. Registration
will open on or before January 10, 2023 and remain open through 12:00
noon EST on January 30, 2023. Registration is available at <a href="https://ntp.niehs.nih.gov/go/commprac-2023">https://ntp.niehs.nih.gov/go/commprac-2023</a>. Interested individuals are
encouraged to visit this web page to stay abreast of the most current
webinar information. Registrants will receive instructions on how to
access and participate in the webinar in the email confirming their
registration.
Background Information on ICCVAM and NICEATM: ICCVAM is an
interagency committee composed of representatives from 17 federal
regulatory and research agencies that require, use, generate, or
disseminate toxicological and safety testing information. ICCVAM
conducts technical evaluations of new, revised, and alternative safety
testing methods and integrated testing strategies with regulatory
applicability. ICCVAM also promotes the scientific validation and
regulatory acceptance of testing methods that more accurately assess
the safety and hazards of chemicals and products and replace, reduce,
or refine animal use.
[[Page 1241]]
The ICCVAM Authorization Act of 2000 (42 U.S.C. 285l-3) establishes
ICCVAM as a permanent interagency committee of the National Institute
of Environmental Health Sciences and provides the authority for ICCVAM
involvement in activities relevant to the development of alternative
test methods. Additional information about ICCVAM can be found at
<a href="https://ntp.niehs.nih.gov/go/iccvam">https://ntp.niehs.nih.gov/go/iccvam</a>.
NICEATM administers ICCVAM, provides support for ICCVAM-related
activities, and conducts and publishes analyses and evaluations of data
from new, revised, and alternative testing approaches. NICEATM and
ICCVAM work collaboratively to evaluate new and improved testing
approaches applicable to the needs of U.S. federal agencies. NICEATM
and ICCVAM welcome the public nomination of new, revised, and
alternative test methods and strategies for validation studies and
technical evaluations. Additional information about NICEATM can be
found at <a href="https://ntp.niehs.nih.gov/go/niceatm">https://ntp.niehs.nih.gov/go/niceatm</a>.
Dated: January 3, 2023.
Brian R. Berridge,
Associate Director, National Toxicology Program, National Institutes of
Health.
[FR Doc. 2023-00147 Filed 1-6-23; 8:45 am]
BILLING CODE 4140-01-P
</pre><script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script></body>
</html>Indexed from Federal Register on January 9, 2023.
This is legal information, not legal advice. Laws vary by jurisdiction and change frequently. Always verify current law with official sources and consult a licensed attorney in your jurisdiction for advice on your specific situation.