Notice2021-19632
Bulk Manufacturer of Controlled Substances Application: Cayman Chemical Company
Primary source
Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.
Published
September 13, 2021
Issuing agencies
Justice DepartmentDrug Enforcement Administration
Abstract
Cayman Chemical Company, has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.
Full Text
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<title>Federal Register, Volume 86 Issue 174 (Monday, September 13, 2021)</title>
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[Federal Register Volume 86, Number 174 (Monday, September 13, 2021)]
[Notices]
[Pages 50904-50907]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2021-19632]
[[Page 50904]]
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DEPARTMENT OF JUSTICE
Drug Enforcement Administration
[Docket No. DEA-898]
Bulk Manufacturer of Controlled Substances Application: Cayman
Chemical Company
AGENCY: Drug Enforcement Administration, Justice.
ACTION: Notice of application.
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SUMMARY: Cayman Chemical Company, has applied to be registered as a
bulk manufacturer of basic class(es) of controlled substance(s). Refer
to Supplementary Information listed below for further drug information.
DATES: Registered bulk manufacturers of the affected basic class(es),
and applicants therefore, may file written comments on or objections to
the issuance of the proposed registration on or before November 12,
2021. Such persons may also file a written request for a hearing on the
application on or before November 12, 2021.
ADDRESSES: Written comments should be sent to: Drug Enforcement
Administration, Attention: DEA Federal Register Representative/DPW,
8701 Morrissette Drive, Springfield, Virginia 22152.
SUPPLEMENTARY INFORMATION: In accordance with 21 CFR 1301.33(a), this
is notice that on July 15, 2021, Cayman Chemical Company, 1180 East
Ellsworth Road, Ann Arbor, Michigan 48108-2419, applied to be
registered as a bulk manufacturer of the following basic class(es) of
controlled substance(s):
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Controlled substance Drug code Schedule
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3-Fluoro-N-methylcathinone (3-FMC)....... 1233 I
Cathinone................................ 1235 I
Methcathinone............................ 1237 I
4-Fluoro-N-methylcathinone (4-FMC)....... 1238 I
Pentedrone ([alpha]- 1246 I
methylaminovalerophenone).
Mephedrone (4-Methyl-N-methylcathinone).. 1248 I
4-Methyl-N-ethylcathinone (4-MEC)........ 1249 I
Naphyrone................................ 1258 I
N-Ethylamphetamine....................... 1475 I
N,N-Dimethylamphetamine.................. 1480 I
Fenethylline............................. 1503 I
Aminorex................................. 1585 I
4-Methylaminorex (cis isomer)............ 1590 I
Gamma Hydroxybutyric Acid................ 2010 I
Methaqualone............................. 2565 I
Mecloqualone............................. 2572 I
JWH-250 (1-Pentyl-3-(2- 6250 I
methoxyphenylacetyl) indole).
SR-18 (Also known as RCS-8) (1- 7008 I
Cyclohexylethyl-3-(2-
methoxyphenylacetyl) indole).
ADB-FUBINACA (n-(1-amino-3,3-dimethyl-1- 7010 I
oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-
indazole-3-carboxamide).
5-Flouro-UR-144 and XLR11 [1-(5-Fluoro- 7011 I
pentyl)1H-indol-3-yl](2,2,3,3-
tetramethylcyclopropyl)methanone.
AB-FUBINACA (N-(1-amino-3-methyl-1- 7012 I
oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-
indazole-3-carboxamide).
(1-(4-Fluorobenzyl)-1H-indol-3- 7014 I
yl)(2,2,3,3tetramethylcyclopropyl)methan
one.
JWH-019 (1-Hexyl-3-(1-naphthoyl)indole).. 7019 I
MDMB-FUBINACA (Methyl 2-(1-4- 7020 I
fluorobenzyl)-1H-indazole-3-carboxamido)-
3,3-dimethylbutanoate).
2-(1-(4-fluorobenzyl)-1Hindazole-3- 7021 I
carboxamido)-3- methylbutanoate.
AB-PINACA (N-(1-amino-3-methyl-1-oxobutan- 7023 I
2-yl)-1-pentyl-1H-indazole-3-
carboxamide).
THJ-2201 [1-(5-fluoropentyl)-1H-indazol-3- 7024 I
yl](naphthalen-1-yl)methanone.
5F-AB-PINACA (N-(1-amino-3-methyl-1- 7025 I
oxobutan-2-yl)1-(5-fluoropentyl)-1 H-
indazole-3-carboxamide).
AB-CHMINACA (N-(1-amino-3-methyl-1- 7031 I
oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-
indazole-3-carboxamide.
MAB-CHMINACA (N-(1-amino-3,3dimethyl-1- 7032 I
oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-
indazole-3-carboxamide).
5F-AMB (Methyl 2-(1-(5-fluoropentyl)-1H- 7033 I
indazola-3-carboxamido)-3-
methylbutanoate).
5F-ADB; 5F-MDMB-PINACA (Methyl 2-(1- 7034 I
(5fluoropentyl)-1H-indazole-3-
carboxamido)-3,3dimethylbutanoate).
ADB-PINACA (N-(1-amino-3,3-dimethyl-1- 7035 I
oxobutan-2-yl)-1-pentyl-1H-indazole-3-
carboxamide).
Ethyl 2-(1-(5-fluoropentyl)-1H-indazole-3- 7036 I
carboxamido)3,3-dimethylbutanoate.
Methyl 2-(1-(5-fluoropentyl)-1H-indole-3- 7041 I
carboxamido)3,3-dimethylbutanoate.
MDMB-CHMICA, MMB-CHMINACA (Methyl 2-(1- 7042 I
(cyclohenxylmethyl)-1H-indole-3-
carboxamido)-3,3-dimethylbutanote)-.
MMB-CHMICA, AMB-CHMICA (methyl 2- 7044 I
(1(cyclohexylmethyl)-1 H-indole-3-
carboxamido)-3methylbutanoate).
N-(Adamantan-1-yl)-1-(4-fluorobenzyl)-1H- 7047 I
indazole-3carboxamide.
APINACA and AKB48 N-(1-Adamantyl)-1- 7048 I
pentyl-1H-indazole-3-carboxamide.
5F-APINACA, 5F-AKB48 (N-(adamantan-1-yl)- 7049 I
1-(5fluoropentyl)-1H-indazole-3-
carboxamide).
JWH-081 (1-Pentyl-3-(1-(4- 7081 I
methoxynaphthoyl) indole).
1-(5-Fluoropentyl)-N-(2-phenylpropan-2- 7083 I
yl)-1H-indazole3-carboxamide.
5F-CUMYL-P7AICA (1-(5-fluoropentyl)-N- 7085 I
(2phenylpropan-2-yl)-1 H-pyrrolo[2,3-
b]pyridine-3carboxamide).
4-CN-CUMYL-BUTINACA (1-(4-cyanobutyl)-N- 7089 I
(2phenylpropan-2-yl)-1 H-indazole-3-
carboxamide).
SR-19 (Also known as RCS-4) (1-Pentyl-3- 7104 I
[(4-methoxy)-benzoyl] indole.
JWH-018 (also known as AM678) (1-Pentyl-3- 7118 I
(1-naphthoyl)indole).
JWH-122 (1-Pentyl-3-(4-methyl-1- 7122 I
naphthoyl) indole).
UR-144 (1-Pentyl-1H-indol-3-yl)(2,2,3,3- 7144 I
tetramethylcyclopropyl)methanone.
JWH-073 (1-Butyl-3-(1-naphthoyl)indole).. 7173 I
JWH-200 (1-[2-(4-Morpholinyl)ethyl]-3-(1- 7200 I
naphthoyl)indole).
AM2201 (1-(5-Fluoropentyl)-3-(1- 7201 I
naphthoyl) indole).
JWH-203 (1-Pentyl-3-(2- 7203 I
chlorophenylacetyl) indole).
NM2201; CBL2201 (Naphthalen-1-yl 1-(5- 7221 I
fluoropentyl)1 H-indole-3-carboxylate).
PB-22 (Quinolin-8-yl 1-pentyl-1H-indole-3- 7222 I
carboxylate).
5F-PB-22 (Quinolin-8-yl 1-(5- 7225 I
fluoropentyl)-1H-indole-3-carboxylate).
4-methyl-alpha-ethylaminopentiophenone (4- 7245 I
MEAP).
[[Page 50905]]
N-ethylhexedrone......................... 7246 I
Alpha-ethyltryptamine.................... 7249 I
Ibogaine................................. 7260 I
CP-47,497 (5-(1,1-Dimethylheptyl)-2- 7297 I
[(1R,3S)-3-hydroxycyclohexyl-phenol).
CP-47,497 C8 Homologue (5-(1,1- 7298 I
Dimethyloctyl)-2-[(1R,3S)3-
hydroxycyclohexyl-phenol).
Lysergic acid diethylamide............... 7315 I
2,5-Dimethoxy-4-(n)- 7348 I
propylthiophenethylamine (2C-T-7).
Marihuana................................ 7360 I
Tetrahydrocannabinols.................... 7370 I
Mescaline................................ 7381 I
2-(4-Ethylthio-2,5-dimethoxyphenyl) 7385 I
ethanamine (2C-T-2 ).
3,4,5-Trimethoxyamphetamine.............. 7390 I
4-Bromo-2,5-dimethoxyamphetamine......... 7391 I
4-Bromo-2,5-dimethoxyphenethylamine...... 7392 I
4-Methyl-2,5-dimethoxyamphetamine........ 7395 I
2,5-Dimethoxyamphetamine................. 7396 I
JWH-398 (1-Pentyl-3-(4-chloro-1- 7398 I
naphthoyl) indole).
2,5-Dimethoxy-4-ethylamphetamine......... 7399 I
3,4-Methylenedioxyamphetamine............ 7400 I
5-Methoxy-3,4-methylenedioxyamphetamine.. 7401 I
N-Hydroxy-3,4-methylenedioxyamphetamine.. 7402 I
3,4-Methylenedioxy-N-ethylamphetamine.... 7404 I
3,4-Methylenedioxymethamphetamine........ 7405 I
4-Methoxyamphetamine..................... 7411 I
5-Methoxy-N-N-dimethyltryptamine......... 7431 I
Alpha-methyltryptamine................... 7432 I
Diethyltryptamine........................ 7434 I
Dimethyltryptamine....................... 7435 I
Psilocybin............................... 7437 I
Psilocyn................................. 7438 I
5-Methoxy-N,N-diisopropyltryptamine...... 7439 I
4-chloro-alpha-pyrrolidinovalerophenone 7443 I
(4-chloro-a-PVP).
4'-methyl-alpha-pyrrolidinohexiophenone 7446 I
(MPHP).
N-Ethyl-1-phenylcyclohexylamine.......... 7455 I
1-(1-Phenylcyclohexyl)pyrrolidine........ 7458 I
1-[1-(2-Thienyl)cyclohexyl]piperidine.... 7470 I
1-[1-(2-Thienyl)cyclohexyl]pyrrolidine... 7473 I
N-Benzylpiperazine....................... 7493 I
2-(2,5-Dimethoxy-4-methylphenyl) 7508 I
ethanamine (2C-D).
2-(2,5-Dimethoxy-4-ethylphenyl) 7509 I
ethanamine (2C-E ).
2-(2,5-Dimethoxyphenyl) ethanamine (2C-H) 7517 I
2-(4-iodo-2,5-dimethoxyphenyl) ethanamine 7518 I
(2C-I).
2-(4-Chloro-2,5-dimethoxyphenyl) 7519 I
ethanamine (2C-C).
2-(2,5-Dimethoxy-4-nitro-phenyl) 7521 I
ethanamine (2C-N).
2-(2,5-Dimethoxy-4-(n)-propylphenyl) 7524 I
ethanamine (2C-P).
2-(4-Isopropylthio)-2,5-dimethoxyphenyl) 7532 I
ethanamine (2C-T-4 ).
MDPV (3,4-Methylenedioxypyrovalerone).... 7535 I
2-(4-bromo-2,5-dimethoxyphenyl)-N-(2- 7536 I
methoxybenzyl) ethanamine (25B-NBOMe).
2-(4-chloro-2,5-dimethoxyphenyl)-N-(2- 7537 I
methoxybenzyl) ethanamine (25C-NBOMe).
2-(4-iodo-2,5-dimethoxyphenyl)-N-(2- 7538 I
methoxybenzyl) ethanamine (25I-NBOMe).
Methylone (3,4-Methylenedioxy-N- 7540 I
methylcathinone).
Butylone................................. 7541 I
Pentylone................................ 7542 I
alpha-pyrrolidinohexanophenone (a-PHP)... 7544 I
alpha-pyrrolidinopentiophenone ([alpha]- 7545 I
PVP).
alpha-pyrrolidinobutiophenone ([alpha]- 7546 I
PBP).
Ethylone................................. 7547 I
alpha-pyrrolidinoheptaphenone (PV8)...... 7548 I
AM-694 (1-(5-Fluoropentyl)-3-(2- 7694 I
iodobenzoyl) indole).
Acetyldihydrocodeine..................... 9051 I
Benzylmorphine........................... 9052 I
Codeine-N-oxide.......................... 9053 I
Desomorphine............................. 9055 I
Etorphine (except HCl)................... 9056 I
Codeine methylbromide.................... 9070 I
Brorphine................................ 9098 I
Dihydromorphine.......................... 9145 I
Difenoxin................................ 9168 I
Heroin................................... 9200 I
Hydromorphinol........................... 9301 I
Morphine-N-oxide......................... 9307 I
Normorphine.............................. 9313 I
U-47700 (3,4-dichloro-N-[2- 9547 I
(dimethylamino)cyclohexyl]-N-
methylbenzamide).
MT-45 (1-cyclohexyl-4-(1,2- 9560 I
diphenylethyl)piperazine)).
[[Page 50906]]
Clonitazene.............................. 9612 I
Isotonitazene (N,N-diethyl-2-(2-(4 9614 I
isopropoxybenzyl)-5-nitronitro-1H-
benzimidazol-1-yl)ethan-1-amine).
Etonitazene.............................. 9624 I
Ketobemidone............................. 9628 I
Trimeperidine............................ 9646 I
Tilidine................................. 9750 I
Acryl fentanyl (N-(1-phenethylpiperidin-4- 9811 I
yl)-N-phenylacrylamide).
Para-Fluorofentanyl...................... 9812 I
3-Methylfentanyl......................... 9813 I
Alpha-methylfentanyl..................... 9814 I
Acetyl-alpha-methylfentanyl.............. 9815 I
N-(2-fluorophenyl)-N-(1- 9816 I
phenethylpiperidin-4-yl)propionamide.
Para-Methylfentanyl (N-(4-methylphenyl)-N- 9817 I
(1phenethylpiperidin-4-yl)propionamide;
also known as 4methylfentanyl).
4'-Methyl acetyl fentanyl (N-(1- 9819 I
(4methylphenethyl)piperidin-4-yl)-N-
phenylacetamide).
ortho-Methyl methoxyacetyl fentanyl (2- 9820 I
methoxy-N-(2methylphenyl)-N-(1-
phenethylpiperidin-4-yl)acetamide).
Acetyl Fentanyl (N-(1-phenethylpiperidin- 9821 I
4-yl)-N-phenylacetamide).
Butyryl Fentanyl......................... 9822 I
Para-fluorobutyryl fentanyl.............. 9823 I
4-Fluoroisobutyryl fentanyl (N-(4- 9824 I
fluorophenyl)-N-(1phenethylpiperidin-4-
yl)isobutyramide).
2-methoxy-N-(1-phenethylpiperidin-4-yl)-N- 9825 I
phenylacetamide.
Para-chloroisobutyryl fentanyl........... 9826 I
Isobutyryl fentanyl...................... 9827 I
Beta-hydroxyfentanyl..................... 9830 I
Beta-hydroxy-3-methylfentanyl............ 9831 I
Alpha-methylthiofentanyl................. 9832 I
3-Methylthiofentanyl..................... 9833 I
Furanyl fentanyl (N-(1-phenethylpiperidin- 9834 I
4-yl)-N-phenylfuran-2-carboxamide).
Thiofentanyl............................. 9835 I
Beta-hydroxythiofentanyl................. 9836 I
Para-methoxybutyryl fentanyl............. 9837 I
Ocfentanil............................... 9838 I
Thiofuranyl fentanyl (N-(1- 9839 I
phenethylpiperidin-4-yl)-
Nphenylthiophene-2-carboxamide; also
known as 2thiofuranyl fentanyl;
thiophene fentanyl).
Valeryl fentanyl......................... 9840 I
Phenyl fentanyl (N-(1-phenethylpiperidin- 9841 I
4-yl)-Nphenylbenzamide; also known as
benzoyl fentanyl).
beta'-Phenyl fentanyl (N-(1- 9842 I
phenethylpiperidin-4-yl)-
N,3diphenylpropanamide; also known as
[beta]'-phenyl fentanyl; 3-
phenylpropanoyl fentanyl).
N-(1-phenethylpiperidin-4-yl)-N- 9843 I
phenyltetrahydrofuran2-carboxamide.
Crotonyl fentanyl ((E)-N-(1- 9844 I
phenethylpiperidin-4-yl)-Nphenylbut-2-
enamide).
Cyclopropyl Fentanyl..................... 9845 I
ortho-Fluorobutyryl fentanyl (N-(2- 9846 I
fluorophenyl)-N-(1phenethylpiperidin-4-
yl)butyramide; also known as
2fluorobutyryl fentanyl).
Cyclopentyl fentanyl..................... 9847 I
ortho-Methyl acetylfentanyl (N-(2- 9848 I
methylphenyl)-N-(1phenethylpiperidin-4-
yl)acetamide; also known as 2methyl
acetylfentanyl).
Fentanyl related-substances as defined in 9850 I
21 CFR 1308.11(h).
Fentanyl carbamate (ethyl (1- 9851 I
phenethylpiperidin-
4yl)(phenyl)carbamate).
ortho-Fluoroacryl fentanyl (N-(2- 9852 I
fluorophenyl)-N-(1phenethylpiperidin-4-
yl)acrylamide).
ortho-Fluoroisobutyryl fentanyl (N-(2- 9853 I
fluorophenyl)-N-(1phenethylpiperidin-4-
yl)isobutyramide).
Para-Fluoro furanyl fentanyl (N-(4- 9854 I
fluorophenyl)-N-(1phenethylpiperidin-4-
yl)furan-2-carboxamide).
2'-Fluoro ortho-fluorofentanyl (N-(1- 9855 I
(2fluorophenethyl)piperidin-4-yl)-N-
(2fluorophenyl)propionamide; also known
as 2'-fluoro 2fluorofentanyl).
beta-Methyl fentanyl (N-phenyl-N-(1- 9856 I
(2phenylpropyl)piperidin-4-
yl)propionamide; also known as [beta]-
methyl fentanyl).
Amphetamine.............................. 1100 II
Methamphetamine.......................... 1105 II
Lisdexamfetamine......................... 1205 II
Phenmetrazine............................ 1631 II
Methylphenidate.......................... 1724 II
Amobarbital.............................. 2125 II
Pentobarbital............................ 2270 II
Secobarbital............................. 2315 II
Glutethimide............................. 2550 II
1-Phenylcyclohexylamine.................. 7460 II
Phencyclidine............................ 7471 II
4-Anilino-N-phenethyl-4-piperidine (ANPP) 8333 II
Norfentanyl.............................. 8366 II
Phenylacetone............................ 8501 II
1-Piperidinocyclohexanecarbonitrile...... 8603 II
Cocaine.................................. 9041 II
Codeine.................................. 9050 II
Etorphine HCl............................ 9059 II
Dihydrocodeine........................... 9120 II
Oxycodone................................ 9143 II
Hydromorphone............................ 9150 II
[[Page 50907]]
Ecgonine................................. 9180 II
Ethylmorphine............................ 9190 II
Hydrocodone.............................. 9193 II
Levomethorphan........................... 9210 II
Levorphanol.............................. 9220 II
Isomethadone............................. 9226 II
Meperidine............................... 9230 II
Meperidine intermediate-B................ 9233 II
Oliriceridine............................ 9245 II
Methadone................................ 9250 II
Dextropropoxyphene, bulk (non-dosage 9273 II
forms).
Morphine................................. 9300 II
Thebaine................................. 9333 II
Oxymorphone.............................. 9652 II
Noroxymorphone........................... 9668 II
Thiafentanil............................. 9729 II
Alfentanil............................... 9737 II
Remifentanil............................. 9739 II
Sufentanil............................... 9740 II
Carfentanil.............................. 9743 II
Tapentadol............................... 9780 II
Fentanyl................................. 9801 II
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The company plans to bulk manufacture the listed controlled
substances for internal use or for sale to its customers. In reference
to dug codes 7360 (Marihuana), and 7370 (Tetrahydrocannabinols), the
company plans to bulk manufacture these drugs as synthetic. No other
activities for these drug codes are authorized for this registration.
Brian S. Besser,
Acting Assistant Administrator.
[FR Doc. 2021-19632 Filed 9-10-21; 8:45 am]
BILLING CODE P
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</html>Indexed from Federal Register on September 13, 2021.
This is legal information, not legal advice. Laws vary by jurisdiction and change frequently. Always verify current law with official sources and consult a licensed attorney in your jurisdiction for advice on your specific situation.