Notice2021-16188

Availability of Six Draft Toxicological Profiles

Primary source

Metadata and text below are from the Federal Register, a public-domain U.S. government work. Always verify the official published version before relying on it for any legal matter.

Published
July 29, 2021

Issuing agencies

Health and Human Services DepartmentAgency for Toxic Substances and Disease Registry

Abstract

The Agency for Toxic Substances and Disease Registry (ATSDR), within the Department of Health and Human Services (HHS), announces the opening of a docket to obtain comments on drafts of six updated Toxicological Profiles: Acetone, Aldrin/Dieldrin, Chlorophenols, 3,3- Dichlorobenzidine, Disulfoton, and Pentachlorophenol.

Full Text

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<title>Federal Register, Volume 86 Issue 143 (Thursday, July 29, 2021)</title>
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[Federal Register Volume 86, Number 143 (Thursday, July 29, 2021)]
[Notices]
[Pages 40844-40845]
From the Federal Register Online via the Government Publishing Office [<a href="http://www.gpo.gov">www.gpo.gov</a>]
[FR Doc No: 2021-16188]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[Docket No. ATSDR-2021-0005]


Availability of Six Draft Toxicological Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), 
Department of Health and Human Services (HHS).

ACTION: Notice with comment period.

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SUMMARY: The Agency for Toxic Substances and Disease Registry (ATSDR), 
within the Department of Health and Human Services (HHS), announces the 
opening of a docket to obtain comments on drafts of six updated 
Toxicological Profiles: Acetone, Aldrin/Dieldrin, Chlorophenols, 3,3-
Dichlorobenzidine, Disulfoton, and Pentachlorophenol.

DATES: Written comments must be received on or before October 27, 2021.

ADDRESSES: You may submit comments, identified by docket number ATSDR-
2021-0005, by any of the following methods:
    <bullet> Federal eRulemaking Portal: <a href="http://www.regulations.gov">www.regulations.gov</a>. Follow 
the instructions for submitting comments.
    <bullet> Mail: Office of Innovation and Analytics, Agency for Toxic 
Substances and Disease Registry, 1600 Clifton Rd. NE, Mail Stop S102-1, 
Atlanta, GA, 30329-4027. Attn: Docket No. ATSDR-2021-0005.
    Instructions: All submissions must include the agency name and 
Docket Number. All relevant comments received will be posted without 
change to <a href="http://regulations.gov">http://regulations.gov</a>, including any personal information 
provided. For access to the docket to read background documents or 
comments received, go to <a href="http://www.regulations.gov">http://www.regulations.gov</a>.

FOR FURTHER INFORMATION CONTACT: Kambria Haire, Agency for Toxic 
Substances and Disease Registry, Office of Innovation and Analytics, 
1600 Clifton Rd. NE, Mail Stop S102-1, Atlanta, GA, 30329-4027, Email: 
<a href="/cdn-cgi/l/email-protection#105144435442447f6840627f76797c7556425e63507374733e777f66"><span class="__cf_email__" data-cfemail="c4859097809690abbc94b6aba2ada8a182968ab784a7a0a7eaa3abb2">[email&#160;protected]</span></a>; Phone: 1-800-232-4636.

SUPPLEMENTARY INFORMATION: ATSDR has prepared drafts of six updated 
toxicological profiles based on availability of new health effects and 
other information since their initial release. All toxicological 
profiles issued as ``Drafts for Public Comment'' represent the result 
of ATSDR's evidence-based evaluations to provide important 
toxicological information on priority hazardous substances. ATSDR is 
seeking public comments and additional information or reports on 
studies about the health effects of these six substances for review and 
potential inclusion in the profiles. ATSDR considers key studies for 
these substances during the profile development process. This notice 
solicits any relevant, additional studies. ATSDR will evaluate the 
quality and relevance of such data or studies for possible inclusion in 
the profile.

Public Participation

    Interested persons or organizations are invited to participate by 
submitting written views, information, and data.
    Please note that comments received, including attachments and other 
supporting materials, are part of the public record and are subject to 
public disclosure. Comments will be posted on <a href="https://www.regulations.gov">https://www.regulations.gov</a>. Therefore, do not include any information in your 
comment or supporting materials that you consider confidential or 
inappropriate for public disclosure. If

[[Page 40845]]

you include your name, contact information, or other information that 
identifies you in the body of your comments, that information will be 
on public display. ATSDR will review all submissions and may choose to 
redact, or withhold, submissions containing private or proprietary 
information such as Social Security numbers, medical information, 
inappropriate language, or duplicate/near duplicate examples of a mass-
mail campaign. ATSDR will carefully consider all comments submitted in 
preparation of the final Toxicological Profiles and may revise the 
profiles as appropriate.

Legislative Background

    The Superfund Amendments and Reauthorization Act of 1986 (SARA) [42 
U.S.C. 9601 et seq.] amended the Comprehensive Environmental Response, 
Compensation, and Liability Act of 1980 (CERCLA or Superfund) [42 
U.S.C. 9601 et seq.] by establishing certain requirements for ATSDR and 
the U.S. Environmental Protection Agency (EPA) regarding the hazardous 
substances most commonly found at facilities on the CERCLA National 
Priorities List (NPL). Among these statutory requirements is a mandate 
for the Administrator of ATSDR to prepare toxicological profiles for 
each substance included on the priority list of hazardous substances 
[also called the Substance Priority List (SPL)]. This list identifies 
275 hazardous substances that ATSDR and EPA have determined pose the 
most significant potential threat to human health. The SPL is available 
online at <a href="http://www.atsdr.cdc.gov/spl">www.atsdr.cdc.gov/spl</a>. ATSDR is also mandated to revise and 
publish updated toxicological profiles, as necessary, to reflect 
updated health effects and other information.
    In addition, CERCLA provides ATSDR with the authority to prepare 
toxicological profiles for substances not found on the SPL. CERCLA 
authorizes ATSDR to establish and maintain an inventory of literature, 
research, and studies on the health effects of toxic substances (CERCLA 
Section 104(i)(1)(B); 42 U.S.C. 9604(i)(1)(B)); to respond to requests 
for health consultations (CERCLA Section 104(i)(4); 42 U.S.C. 
9604(i)(4)); and to support the site-specific response actions 
conducted by the agency. Public nominations for substances from the SPL 
(or other substances)for toxicological profile development were 
requested on April 18, 2018 (83FR17177-17178).
    ATSDR has now prepared drafts of six updated toxicological profiles 
based on availability of new health effects and other information since 
their initial release.

Availability

    The Draft Toxicological Profiles are available online at <a href="http://www.atsdr.cdc.gov/ToxProfiles">http://www.atsdr.cdc.gov/ToxProfiles</a> and at <a href="http://www.regulations.gov">www.regulations.gov</a>, Docket No. 
ATSDR-2021-0005.

Donata Green,
Acting Director, Office of Policy, Planning and Partnerships, Agency 
for Toxic Substances and Disease Registry.
[FR Doc. 2021-16188 Filed 7-28-21; 8:45 am]
BILLING CODE 4163-70-P


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